Lagopus muta (rock ptarmigan): 125689219 Help Entry 125689219         CDS       T09141                                  Symbol SYNE1 Name (RefSeq) nesprin-1 isoform X1   KO K19326   nesprin-1 Organism lmut  Lagopus muta (rock ptarmigan) Pathway lmut04820   Cytoskeleton in muscle cells Brite KEGG Orthology (KO) [BR:lmut00001]  09140 Cellular Processes   09142 Cell motility    04820 Cytoskeleton in muscle cells     125689219 (SYNE1)  09180 Brite Hierarchies   09182 Protein families: genetic information processing    03036 Chromosome and associated proteins [BR:lmut03036]     125689219 (SYNE1) Chromosome and associated proteins [BR:lmut03036]  Eukaryotic type   Centrosome formation proteins    LINC complex     125689219 (SYNE1) BRITE hierarchy SSDB OrthologParalogGene clusterGFIT Motif Pfam:  Spectrin Spectrin_SYNE1 SYNE1 CH KASH Motif Other DBs NCBI-GeneID:  125689219 NCBI-ProteinID:  XP_048792073 LinkDB All DBs Position 2:61089753..61375780 Genome browser AA seq 8818 aa AA seqDB search MAHYKGASGRNVTSLHLFSGTFQHRQDEQELVQKRTFTKWINTHLAKRNPPMMVSDLFED IKDGIMLIALLEVLSGQKLPCEQGRHLKRIHWVANIGTALKFLEGRRSVYRGSPIKLVNI NSTDIADGRPSIVLGLVWTIILYFQIEELTSNLPQLQSLSSSASSVESVVSSETASPPSK RKVVTKVQGSAKKALLKWIQYTAARQVGIEIKDFGQSWRSGVAFHSIIHAIRPDLVDMEK VKGRSNRENLEEAFTLAETELGIPRLLDPEDVNVDKPDEKSIMTYVAQFLKYYPDPHHTM ADVQENDKEDKLMLRDLRVWAEQFERDLARAQVAETSLQEKYQSFKHFRIQYEMKRKPIE LVTQSLRKDGKLSLDQAIVKQAWDRVSSRLFDWHILLDKSLPAPLGTIGAWLYRAEAALR EEVSIQQAHEETANIIHRKLEQLKDLLKNIEGHKKTFHEIHGARSVNGVPVPSDQLEDMA ERFNFVVSSSELHLLKMEFLELKYRLLSLLVLAESKLKSWIIKYGRRDSVELLLQNYISV IENSKFFEQYEVTYQILKRAAEMYAKANGSVEEVESVMKFMSETTAQWRNLSVEVRSVRS MLEEVIANWDRYSSTVAGLQAWLEDAEKMLNQTEQSKKDFFRHLPHWIQQHTAMNDAGNF LIETCDETISRDLKQQLLLLNGRWRELFMQVKQYARADELDKMQKDYLDGVANLTAFVDE SNRKFSAPVEVSFLDVKMFVQDLENIKQKLPAMEAQYKMVARTAQLVMKEVSQEEINEML ATLTKMKEQLSKVKENSCALLYECQHLLSPLEEQEKQITNFYESLEKVNEIISILDPEAQ PTTVLKQKAQDLVAYQENCKKALSLIERNSQNILQCVASSEVVKHFHHSTFQKKVTQVQI TFQNMVRKAGDWRKNIEVNSRLMKKFEESRAELEKVIQIANCCLKEKGNPEELLRKHSEF FNQLDQRVLNAFLKACDELTDILPEQEQHSLQEAVRKLHRQWKDLQMEAPYHLIHLKIEV QKIKLLVTVEECKAELARQNKVLTREGKERMIEDHKLFFGDKGSYHLCEKRLQRIEELCH KLPVSDPVRATLESSQRILKELKSQIDSTYTKLTEHSDIWKSYTNRFSELANWISSTERE LKRIKESVNDTAKYEQFKSSVGEIRQHINKEGENHSWLKSRLAVITKICTDVEAKKTEDE LCKLSSDFKGLLDLLAEIERTLGTVGDCVQYKEEVKSAIEELINNSKEAQAEAEKILDTE SLLQAQQLLFHHQQRTRRLRAKRQGVQQQIFQAKQLQIEGGLPSAMQEDLLKLEGTLENM QQTMEKREEQLQVTINKWEQFERDKETVVKYLNQASCALERILNFSSLESLSSELDQTKE LSKHNEAMAVQAENLVKNSSEIQLGSKRKQALQQQAKSIQEQVKKVDVTLEEDLKRMEMM KNKWDHFGKNFEALSTWIAEKEKELETLETLSSPLDTQISQIKVINTEIDSKINGISKLE EEAKSFTQFVTSGECAHIKAKLTHIKRYWEELREHAQRLEGTIAGNASAQKIYEESLKQV QQSVSEIETKLAEPLTSCTSSSATYGDLQDCTDLCHTVEKLSNTLASLSVCARKAANKEK AAQEVTALQQRYEKVLENAKEKQMLLETLLARWQKQEKELCAFQIWLEGCEAAARPSEQY VSADRVKLEGELQSLQDLRADFESHASVYVSLLQLNESLFPTASKQCVKAIKEKCKELDE RWKALPQTIDKRINFLQSLVAEHGQFDELLCSFSEWIKQFLAELQSTSEINTADQELAAS HNKNHSTEIESKKQQLQSLKDLVDKLCVFSCPEDQQTLQGKTEDCFQIFQEANQITNQRK EALDQLQVFLELHNAASKKLHQLRQTVEKTGNMDKAKSELLEKDLHDVIQSLNKLESIAI SLDGSLTKAQYHLKHGISEQRTSCRAVVDHLYLELEAVQNLLGTKQSEAEALATLRRSFM ERKEELLKNVEDTEEKADKEGLREATLQALQQRLRIFNQLDEELSSHQHELQWLMDKAKQ IAQKDITLAPEIDKEINHLASLWEDTKKVIQEKKEQSCILIDLIKEYHGLKSTVMKVIDS ADSASVIKSIWKDREDIKRTLSKHEAAKNDLSDKQKDLDIFTNKGKHLLAELKKVQNCDC TMVKTDMNSTVDKWLDVSERIEDNIHQLSLGVSLWDDILKIADEMDGWCTNCISHLNEGI SNLSNSLRMEVILKDFQSQVKDKEQKLEQLSSKISELKELSHSQEPPADLQFIESDLRQK LEHAKEMSQTAKETLKDFSSQKMQLQKFIDKMTHWLIETEETLLRCSRNLDPEALNLVKE TQKDLQLQQSSIDSTRENLNRLCRKYHSVELETLGGTVTSLIKKYEAVNQLCSRTQANIQ ECLEKHFLYTMQEFQEWFSDVKAAVKELSDRSGDSKAIEAKLHDLQSVLDSLSEGQNKLD AASKEGENLYTCLPQPAVIHIQEQVAKSNQNFKEFLSQCLNDKQALEACASYLGSFEEQH KKFSLWIHNMEERMSTEALGEIKELIPEKKKEVQKVEKFLEELLASRESCEKLAQIAQAL NEEGHGAGREVRLASQHLTNYQNMVKTVKEKLQTCQLALQEHLTLEEALQSMWSWVKEVQ EKLALAESTVGSKATLERRLTQIQEILLLKGDGEVKLNMAIGKGEQALRSSNEEGQKVIQ TELQKLKDVWNDIISTSMSWQSCLESLISQWNEYLEKKSQLEQWLEKLDHKVEQPLEPQI GLKEKFAQLDYFQAIVSEIEDHSGDFQQLAEKTAELYKKTEDDSFGAAAQEELETQFNDI TTVAKEKMKKVEDIVKDHLLYLDAVHEFTDWLHSAKEELHRWSDATGDTSVIQKKLAKIN ELVDSRQIGAGRLGRVETLAPAAKRSTSAGGCQLLAAEMQALQLDWKQWEESAFQSQRSL RDVLSQMAVSEQEFATEVARLEEAVQRFGGLLAAWSQSLTPLDSRHTDAEIVESWRKEKE TSDALIKSEHVIDEIKTQLNDLCRFSRDLSTHSSKVSGLIKEYNSLCLQASKGCQSKEQI LQQRFRMSFRDFQQWLVNAKVTTAKCFDVPQDISEASASLQKAQEFLSESENGQQKLNLV ASKGELLCSILPKEKAKVILDKCAMAKEDWKNFISALRQKESALENLKIQMKDFEATAEP LTEWLSTTEKMVQGSSSRLHDLPSKRREQQKLQSVLEEISCHEHQLNRLKEKAQQLLEEQ AVSKSFMRRVSQLSSQYLTLTNLTKEKVSKMDRIVAEHQQFSHDFKDLQDWVADAIHMLE SYCHPTADKNVLDSRMLKLEGLLTLKQEKEIQMKIILTRGESVLQNTSLEGVQVIEQQLH TLKDSWASLLSACIRCKSQLEGALSKWTSYQDDVRQFTSWMDKVEASMNSSQRQCAELRE KAAALSKAKLLSEEVLSHSSLLETIEVKGSGMAEHYVTQLELQELQERYKLLKDRTREAV KKAEELLNLHQGYQRNLKAFETWLEEEQEKLSCLSHLEGDAQKQEATLRDLQELQVCCAE GQALLNAAVRAREEVIPWGMPQIEDRALESIRQDWQVYQHNLCEARSQLNATVSRLRLME KKFQKVNDWITELEEKVDIRTGRQSGRATKEMQLQQMKKWHEEITIYKDDVEEVGILAQQ ILEEGLTTSGMGSQATQLTSRYQTLLLRILEQTKFLEEEIRSMEESELAFSAYKNWYGAT NKDFRNVITKFDVLDKTAMEKKVQKLELLLSDMDIGHSLLKSAREKGERAIKYMEENDVD CLRKEIGDHVEQLEDLAGSIRKEHVTSEKCLQLAKEFSDKYRAQTQWLTEYQVMLHTPVE PKCELYEKKAQLSKYKSIQQTILSHEPSIKSVIEKGEALFDLVNDVTLKSNIQDLQSNYH ELCSATKACVETLEVRVKEHEDYNSDLQEGEKWLLHMSSKLVSSDLMESNSLEIITQQLA NHKAIMEEIAGFEDCLNKLKSKGDYLISQCTEHLQAKFKQNIQSHLQGTRDSYSAICSTA QRVYQSLEHELQKHVNHQDTLQQCQTWLSTVQSELKPSTWTPFSLADAVKQVKHFRALQE QANTYLDLLCSMCDLSDATVKSTATDIQQTKQMIEQQIMHSQYLAQGWEEIKQMKAELWM YFQDADQQLQNLKRRRAELELSVAQNMVLQIKEFSQKLQSKQSALTSVTEKINKLTQGQE SPEHKEIGQLSNQWLDLCLQAHSLLIQREEDLQRTVDYHDRMNVVEVFLEKLTKEWDNLA RSDAESTNVHLEALQKLALTLQERRFALEDLKDQKQKMVEHLNLDDKELVKEQFGHFEQR WTQLEELVKRKIQISVSTLEELSLVHSKLQELMEWAEEQQPSISEALKHSPPPDLAQSLL MDHLTISSELEAKQLVLKTLLKDAERVMTSLGLNERQELQKALSDAQHHVDCLSDLVVQR RKHLNKALSEKTQFLMAVFQATNQIHQHEKKVTFPEHICLLPEDVNKQIRTCKNAQASLK AYQNEVTGLWAQGRDLMKEATEQEKSEVLGKLQELQNIYDTVLQKCTQRLLELEKNIVSR KYFKEDLDKACHWLKQADIVTFPEVNVMNSNSELYTQLSKYQQILEQSPEYENLLLTLQR HGQEILPSLNEVDHSYLDEKLNILPQQFNTVSALAKDKFYKVQEAIYARKEYTSLIELTT KALTELDDQFISMDKAPAAVLAKEALALQQAYKDLLGEVMSLGAAVDELNQKKEAFRSTG QPWQPDEMLKLVTLYHKLKRQIEQKINLLEDTIEACQEHEKMCSQLEAQLEAVKNEQIKV NEEMLPIEEKLKIYHSLVGSLQDSGSLLKRITEHIETLSPQLDPSARETTNHQVLSWQDK LKNLHAAIGDIVMDCENRLVQSIDFQTEICRSLDWLRWVKTELNGKLSLDLKLQSIQEEI RKVQIHQEEVQSSLRVMNALSNKEKERYMKAKELIPADLENTFAELTELDGEVQEAIRIR QATLDKLYSLCQRHYQVIQTTNDWLEDAQEFLHLTRNGLDVENSEGNLRNHIEFFSTESQ FSNNLKELQDLVPELEPFIHATAREQLMQNLASLEEKGRGTKQEANNQQELLQRCASEWQ EYQTARQKVIEVMNEAEKKLSDFSVAKAASFHEAEEKLQTHKTLVSVVNSFHEKITTLEE KVSQLEEVSNDASKAAVSRSMTTVWQRWTRLRNVAQEQEKILEDAIQEWNGFNDKIQKAT VVIDQLQDRLPESSVEKASKTELLELLDYHSSFLLEVEHQLSSLGLLKQHALNMLQDVEI KPLSQEEIPVMQEVKAMQDRCHNMQQKVKNSVKLVKQELKEREEVEAQINVVKTWIQETK EYLLSPDVEVDTQLQELKSLLCEATTHRQAVEKMAEQQQNKYLGLYTILPSELSLHLAEV GLALVTVQDQIQAKEKETGHIKTLNQEFQQRIQGIANELNVILSKLKRKTDDIVQAKLEQ KILGEELDSCNLKLLELDASVQEFSEQNIPLAKQLANRIGKLTALHQQTIRQAEYRATKL SQATSHLEEYNEMLEFILKWIEKANILVHGNITWNSSSQLRDQFKAYQTMLEESGEIHDD LEVMSERIEYLASVYLTEGMSHQVLELGRRTEELQQIIKVRLPNLQDAAKDMKKFEVELR ALQAALEQAQATLTSPELGRLSLKEQLSHRQHLLSEMESLKPKVHAVQVCQSALRIPEEV VTSLPICHSALQLQEEASRLQHTAIQQCNIMQEAVVQYEQYEQEMKHLQQMIESAHREIQ DKPVATSNIQELQNQISRHEELAQKIKGYQEQIASLNSKCKMLTMKAKHATMLLTVTEVE GLSEGMEELDSDLLPAHPAHPSVVMMTAGRCHTLLSPVTEESGEEGTNSEISSPPACRSP SPVANTDASVNQDIAYYQALSAEQLQTEAAKIQPSTSATQEFYEPGLESAASAKLDDLQR SWETLKNVISEKQRTLYEALERQQKYQDTLQSISTKMETTEMKLNESLEPAKSPESQMAE HQALMDEILMLQEEITELQTSLAQELVSESLDAEAADQLALQSTLTVLAERMATIRMKAS GKRQLLEEKLSEQLEEQRQEQTLQRYRCEADELDHWLLNTRATLDNTLLTAEEPMDMEAQ LVDCQNMLVEIEQKVVALSELSVHNENLLMEGKAHTKDEAEQLALKLRTLKGSLLELQKV LHDKQINIQQGSLQEKEENNLDLVSSQSPSVQEWLAQARTTRSQQQQSTLQQQKELEQEL EEQKNLLRSVACRGEEILTQHGIPEGLCISENPEKLSEELCLEGEKSSPEQQLKVKWESL NHKFSTKQKLLQKTLEQEQLQIYSRPNRLISGLPLYKENGQDEEKSSVSPVLVELNQAFE DVSSETGQVEKESLHLEQKLYDGVASTSLWLDGVEEQVFVATALLPEEETETYLCKQESL AKEIKDITEEVDKNKNLFTQIFPENGDNREVIEDTLDCLLRRLTLLESVVNQRSHQMKER LQEIMAFKNDLKLLYTSLADSKYLVLQKLSEAVEKPETEQIQVIMQAEESLKELDAGISE LKKSVDKLQIDQPSVQELSKLQDMYDEVMMIIGSRRSNLNQNLALKRQYERALQDLADLV ETGQEKMDGDQKMIVASKEEVQSLLNKHKEYFQGLESHMILTETLFRKMSCFALLKETRS HSELMTQASTVLKLAHKRGVELEYILETWMHLDEDYQELTRQLESVEGNIPTVGLVEETE DKLTERIKLFQHLRSNLTEYQPKLYQVLDDGKRLLFSVSCSDLESQLNQLGEHWLSNTSK VNKELHRLETILKHWTRYQSESTELTHWLQSAKERLEFWSQQSLTVPQELETVRDHLNSF LEFSKEVDAKSSQKSSVLSTGNQLLRLKKVDTAALRAGLSHIDSQWTELLSQIPTVQEKL HQLQMDKIPSRHAITEVMSWISLMENVIYKDEESIKNIIGQKAIQDYIQKYKGFKIDLNC KQLTVDFVNQSVLQISSQDVESKRSDKTDFAEQLGAMNRRWQILQGLVTEKIQLLESLQE SWTEYENNVQCLKSWFEAQEKKLKKQQRIGDQASVQNALKDCQELEESIRAKEKELESIE KSGLSLIQNKKEEASSAVLNTLQEINHSWASLDHMVSQLKILLQSVLDQWSIYKVTYEEL NSYLMEARYSLSRYYLLTGSLEAVKVQVDNLQSLQDELEKQENSLQKFGSMTNQLLKECH PPVTETLTNTLKEVNMRWNNLIQEIAERLHSSKGLLQLWQRYKDCYQQCSSTVHLREDQT NELLKSATSKEIADDEVTTWIQDCNDLLADIKTAQDSLIVLQELGEELKSRVEASAAAAI QSDQLSLNQNLLALEQALCKQQTVLQAGVLNYQTFAKNLQDLETWVTEAEAKLKGQDPGH ASDLSAIQSRMEELKSQMLKFSSMTPDLDRLNELGYRLPLNDKEIKRIQNLNRQWSLISS QATERFSKLQSFLLQQQTFLEKCETWMDLLVQTEQKLAAEISGNYQSLLEQQRAHELFQA EMFSRQQILHSIISDGQHLLEQGQVDDRDEFNLKLTLLSNQWQGVIRRAQQRRGIIDSQI HQWQRYREMAEKLRKWLVETSCQPVSGLGNAPIPLQQARALLDEVQLKEKVLLRQQGSYI LTVEAGKQLLLSADSGAEAALQAELTEIQEQWKKVSTQLEEQKKQVALLLKDWERSEKGI ADSLEKLRSFKKKLSQPLPEHHDELNAEQIRCKELENAVDGWTDDLAHLSLLKESLSTYI SADDTSVLSERIELLHRQWEELCHQVSLRRQQVSEKLNEWAVFSEKNKELCEWLTQMESK VSQNGDIVIEEMIEKLRKDYQEEIAVAQESKIQLQQMGERLAKASHESKASEIEYKLGKI NDRWQHLLDLIAARVKKLKETLVAVQQLDKNMSSLRSWLAHIESELSKPIVYETCDSEEI QRKLNEQQELQRDIEKHSTGVASVLNLCEVLLHDCDACATETECDSIQQATRNLDRRWRN ICAMSMERRLKIEETWRLWQKFLDDYSRFEDWLKNSERTAAFPSSSGVLYTVAKEELKKF EAFQRQVHESLTQLELINKQYRRLARENRTDSDCSLKQMVHEGNQRWDNLQKRVTSILRR LKHFIGQREEFETARDSILVWLTEMDLQLTNIEHFSECDVQAKIKQLKAFQQEISLNNNK IHQIIVQGEQLIEKSEPMDAAVIEEELDELRRYCQEVFGRVERYHKKLIHLPLTDDEHDL SDREVDLDESADLSDIHWHDKSADSVLSPHPSSNISLPLAQPVRSERSGRDTPASVDSIP LEWDHDYDLSRDLETAVSRALHSEEEDGEQEKDFYLRGATSIADVEIPETLEAYVTLTEN ALKNISGEPGALEAHIRQLDKALDTSRFQIQQTENIIRSKTPTGPELDATYKGYMKLLSE CSGSIDSVKRLGYKLKEEEEKLSGLINLNSTETQTAGVIDRWELIQAQALSKELRMKQNL QQWQQFNSDLNSIWAWLGETEEELEKLRRLDLSTDIQTIELRIRKLKELQKAIDNRKAII LSINLCSSEFTQSDSEESKKLQERLSQMNICWDHVCSMIEDWRCSLQDALMQCQDFHEMS HGLLLWLENIDRRKNEIVPINPNLDSEILQDHHRLLMQIRRELLESQLKVASLQDMSCQL LVNAEGKDCLEAKEKVHVIGNRLKLLLKEVIRHIKDLEKALDISSSQLDLSSWSSADELD TSGSVSPVSGQSTPSRQRTPRGKCSLSQPGPSVSSPHSRSIRDGSGSSPSEAGPAWQHPS FFLRVLRAALPLQLLLLLLIGLACLVPMTEEDYSCTMANNFARSFHPMLKYMNGPPPL NT seq 26457 nt NT seq  +upstreamnt  +downstreamnt atggctcattacaaaggtgccagtggcagaaatgttacatcgttacatctgttttctggg acctttcaacatcggcaggatgagcaagagttggtacaaaagaggacttttacaaaatgg atcaatactcatctggctaagcgcaatcctcccatgatggtcagtgatttgtttgaagac atcaaggatgggataatgctgatagcccttttggaggttctttcagggcagaagctgcct tgtgagcaaggacgtcatctgaagagaattcactgggttgccaacattggcacagcactt aagtttctagaaggaagacggtctgtataccgaggatctccgataaagcttgtcaacata aactcaactgatattgctgatggtcggccttctattgtgcttggcttggtgtggaccata attttatattttcagattgaagagctcaccagcaatcttccacagctgcagtcattgtct agcagcgcgtcctctgtagagagtgttgtcagttcagaaactgcaagtcccccaagcaaa cggaaggtggtaaccaaggtccaaggaagtgccaagaaggctttgttaaaatggatccag tatacagctgcaaggcaagttggaattgaaatcaaagactttggacaaagttggaggagt ggtgttgcatttcattccattattcatgctatccgtccggatttagtagacatggagaaa gtaaaaggaagatcaaacagggaaaacctggaagaagccttcacacttgcagaaacagag ctagggattccgaggctccttgatccagaggatgtgaatgttgacaagccagatgaaaag tctatcatgacctacgtagcccagtttttgaagtactatcctgatcctcatcatacaatg gctgatgtgcaggagaatgataaggaagacaagttgatgctgagagacctaagagtgtgg gcagaacagtttgaaagagatttagcacgggcacaggtggcagaaacaagcttacaggag aaatatcagtcatttaagcatttcagaatccagtatgagatgaaaaggaaacctattgaa cttgtaactcagtccttaaggaaagatggtaaattatcacttgatcaagctatagtgaag caagcgtgggacagagtctcttccaggctgtttgactggcacatactccttgataaatct cttcctgcacctttgggtaccataggtgcttggctctatagagcagaggctgctctaaga gaagaagtaagcattcagcaagctcatgaggagacagcaaatattatacaccggaagctt gaacaacttaaggatctattgaaaaacatagaaggtcacaaaaagacattccatgagatc cacggggcaaggtctgttaatggagtgcctgttccatctgaccaattagaggatatggca gagaggtttaattttgttgtctcttcgtctgagctccatctgttgaaaatggagttcctg gaactgaagtaccgtctactgtcactcttagtccttgcagaatcaaagttaaaatcatgg attattaaatacggaagaagagactcagtggaactacttctgcaaaattacatatctgtt attgaaaacagtaagttctttgagcaatacgaggttacataccagatcttgaaaagagca gctgaaatgtatgccaaagcaaatggctcagtggaagaagttgagagtgtgatgaaattc atgagtgaaacaacagcacagtggaggaacctctcggtagaggtgagaagtgtaagaagt atgttggaagaagtaattgctaactgggacaggtacagcagcactgtggcaggtctgcaa gcctggttggaggatgctgaaaaaatgcttaatcagactgaacagtctaaaaaggatttc ttcaggcacttaccccattggatccaacagcacacagccatgaatgatgctggtaatttt ctgattgaaacatgtgatgagaccatttccagagaccttaaacagcaacttctgttacta aatggaagatggagagaattgtttatgcaagtgaagcaatatgctcgggcagatgaattg gacaagatgcagaaagattacctggacggcgtggctaatttgacagcttttgttgatgaa agtaatagaaaattttcagcacccgtagaagtgtccttcttagatgtgaagatgtttgta caagatctagaaaatattaagcagaagttgcctgccatggaagctcagtacaaaatggtt gcaagaacagcacaactggttatgaaagaagtttcccaagaagaaataaacgaaatgctt gcaactttgacaaagatgaaagagcaactaagcaaggtcaaggagaattcctgtgcccta ctgtatgaatgtcagcatctgctgtccccacttgaagaacaggagaaacaaatcacgaat ttctatgaatctcttgaaaaggtcaatgaaataatttctatcttggatcctgaagcacag cctacaactgttctgaagcaaaaagctcaagatttggtagcttatcaagaaaactgcaag aaagctttgtccctcattgagagaaatagtcagaatattctgcagtgtgtggcttctagt gaagtggtaaagcatttccatcactcaacgtttcagaagaaagttacacaagttcagatt acttttcagaatatggtcaggaaagctggtgactggaggaaaaacatagaagtaaatagc cgtttgatgaagaaatttgaggagtctagagcagaactggagaaagtaatacagattgcc aattgttgcttaaaagaaaaaggaaatcctgaagagcttctcagaaagcatagcgaattt tttaaccagttggaccagagagtcctaaatgccttcctgaaagcttgtgatgaacttact gacatccttcctgaacaagagcaacacagcctgcaggaagctgtgaggaaactccatagg cagtggaaggatcttcaaatggaagccccatatcatctgatccatttgaagattgaagtg cagaaaattaagctcctggtcacagtggaggagtgcaaagctgaactagctcgacagaat aaggtgctcaccagagaaggcaaagaaaggatgattgaagaccacaagttgttctttggt gacaagggatcttaccatctctgtgagaaaagattacaacggattgaagaactgtgccat aaacttccagtttctgatccagtgagggctacgttggaaagtagccaacgaatcctgaag gagctcaaatctcagatagacagtacatacacaaaactaacagagcattcagacatctgg aagagctatacaaacagattttctgaattggcaaattggatttcatctacagaaagagag ctaaagaggataaaggaaagtgtcaatgatactgctaaatatgagcaatttaaatcatct gttggggaaatcaggcagcatattaacaaggagggagaaaatcatagctggctgaaatct agacttgcagttattactaaaatatgtaccgatgtggaggccaagaaaacagaagatgag ctttgtaaactttccagtgacttcaaaggacttctagatttgctggctgagattgaaagg acattaggtactgttggagattgtgtccagtataaagaagaggttaaaagtgcaatcgaa gagttaatcaacaactctaaggaagcccaagcagaagctgaaaagatcctggatacggaa agtttattgcaagctcagcaactactgtttcatcatcagcaaaggacaaggagactccgt gcaaagagacaaggtgtgcaacagcagattttccaggctaaacagttgcagattgaaggt ggactgccaagtgcaatgcaggaagatttactaaagctagaaggaacactggagaacatg cagcagactatggagaaacgtgaagagcaattgcaagtcacaataaataaatgggagcag tttgaaagagacaaagaaacagtagtaaaatatttaaatcaagcaagctgtgcgcttgaa cgtatcttaaactttagcagtttagagagcctctcctcagaactggatcagacaaaggaa ctttctaaacacaatgaagccatggcagtacaagctgaaaacttggtgaagaattcttct gagatacagcttggttcaaagagaaaacaagccctgcagcagcaggcaaaatctatccaa gaacaagtaaaaaaagtggatgttactctagaagaagatcttaaaagaatggaaatgatg aaaaacaagtgggatcattttggcaaaaattttgaagctctatccacctggatagctgaa aaagaaaaagaactggaaactttggaaacactctcatctcctttggacacacagatcagc caaatcaaggttattaatacagaaatagacagtaaaataaatggaatctcaaaactagaa gaagaagccaaatcatttacccagtttgttacttctggagaatgtgcacatattaaagcc 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cagatctacagcagaccaaatagactgatttctggactgcctttgtataaggagaatgga caggatgaggagaaatcatctgtgtcaccagtattggttgaactaaatcaggcctttgaa gatgtgtcatctgagactggacaggtggagaaggaaagtctacatcttgaacagaagctg tatgatggagttgcatctacctccttatggctagatggtgtggaagaacaggtatttgtt gctacagctctgctgccagaggaagaaacagaaacatacctctgcaaacaggagtctctt gccaaagaaatcaaagacataacagaagaagtggataagaacaagaatttatttactcag atatttcctgagaatggtgataatagggaggttatagaagacactttggattgtctcctg agaagactgaccttactggagtctgtagtaaaccagagaagccatcagatgaaagaaagg ctacaggaaataatggccttcaagaacgacctgaaactcctgtatacttcactggctgat agcaaatacttggttctacagaaactgtcagaggcagttgagaaaccggaaacagaacaa attcaggtcataatgcaggcagaagaaagtttgaaggaattagatgctggaatcagtgaa ttaaagaagagtgtagataagctacaaatagaccagccttctgtacaagagctatctaag ttacaggatatgtatgatgaggtgatgatgataattggatccagacggagtaacctgaac cagaatctggctcttaagaggcagtatgagcgggctttgcaagacctggctgatctggta gaaacaggccaagaaaagatggatggtgaccagaaaatgatagttgcttctaaggaagag gttcaatcactacttaacaagcataaggaatattttcaggggttggagtctcacatgatc ctgacagagacactcttcagaaagatgagttgttttgcccttttgaaggaaactcgatca cattcagaactaatgacacaagcttcaactgtattaaagctggcacataaacgaggtgtg gaactggaatacattctagagacttggatgcatcttgacgaagattaccaggaacttacc agacaactggagtctgtcgaaggtaacattcccactgttggtttggtagaagagacggaa gacaagctcacagaacggattaaactttttcagcatctgagatctaacctgactgaatat cagcctaaattatatcaggtgctggatgatgggaaaaggctacttttttctgttagttgc tcagatcttgaaagtcagctgaaccaactgggagagcactggctaagtaacaccagcaag gttaacaaggaactgcacaggctggagacaatactgaagcactggacaaggtaccaaagt gaatcaactgaactgacacactggttacaatctgcaaaagagcgacttgagttctggagt cagcagtctctgacagttcctcaggaactggaaactgttcgagaccacctgaattccttt ttggagttttcaaaagaagtggatgctaaatcgtcacagaaatcttctgtactgagcact gggaaccagctcctcagactgaagaaggtagatacagcagcgttgcgtgcaggattgtcc cacattgacagtcagtggacagagctgctctcacaaatcccaacagtacaagagaaattg caccagctgcagatggacaaaattccttctcgccatgctatcactgaagttatgagctgg atttccctgatggaaaatgttatttataaagatgaagagagtataaaaaacataataggg caaaaagccattcaggattatatccaaaaatacaagggtttcaagatagatttaaattgc aaacaattgactgtagactttgtgaaccaatctgtgctacaaattagcagccaagatgtt gaaagtaaacgtagtgacaaaactgattttgcagaacagctcggagcaatgaatagacgt tggcagattctacaaggcttggtaacagaaaagatccagctgttggaaagtctgcaagaa tcctggacagaatatgaaaataatgtgcagtgcctaaaatcttggtttgaagcccaagag aagaagctgaaaaaacaacagagaattggagaccaggcttcagtacagaatgctttgaaa gattgtcaggaattagaagaatcaataagagcaaaggaaaaagaattagaaagcatagaa aaaagcggtctgtctttgatacaaaacaagaaggaggaagcctcttctgctgttttgaat acactgcaagaaatcaatcattcctgggccagcttggatcacatggttagccaactaaag atactgttgcagtctgttcttgatcagtggagcatttacaaagtaacttatgaagaacta aatagttacctgatggaagccagatattctttgtcccgctattatcttcttactggttct ttggaagctgtgaaagtccaagttgataacttacagagcctacaagatgaactggaaaaa caagaaaatagcttacagaaatttggttcaatgaccaatcagctattgaaagaatgtcac ccaccagtgactgaaacccttaccaacactttgaaggaagtgaatatgagatggaataac cttatacaagagattgcagagcgactacattccagtaaaggtctccttcagctgtggcag aggtacaaggactgttaccagcagtgctcttctactgtccatttacgagaagatcagacc aatgaattgttgaagagtgccactagtaaagaaattgctgatgatgaagtaaccacctgg attcaagactgcaatgaccttcttgctgatataaagacagcacaggattcactgattgtt cttcaggaactgggagaggagttaaaaagccgggtggaggcctcagcagcagcagctata cagtctgatcagctgtctctaaaccagaatctattagccctagaacaagctctatgcaag caacaaactgtacttcaggctggtgtattgaactatcaaacgtttgctaagaacctgcaa gatcttgagacctgggtaacagaagcagaagcaaaactgaaaggacaggatcctggtcat gcatctgatctctcagcaatacagagcaggatggaggaactcaaaagtcagatgttgaag ttcagcagcatgaccccagatttggaccgtcttaatgagctgggttacaggcttcctctg aatgataaagaaatcaaaagaatccagaacctgaacaggcagtggtctctgatctcgtct caggctacagagagattcagtaagctgcagtctttcttgctacagcagcagacattcttg gagaaatgtgaaacttggatggatttattagttcagactgaacagaagctggcagcagag atttcaggaaactaccagagtcttttagagcaacagagagcacatgagctattccaggca gagatgttcagccgtcagcagattttgcattcaatcatctctgatggacagcacctccta gaacaaggacaagtagatgacagggatgaatttaatctgaagctgacacttctgagtaat cagtggcaaggagtaattcgccgggcacagcagaggagagggattattgacagccagatc catcagtggcagcgctacagggagatggcagagaaactacgcaagtggctggtggaaaca tcctgtcagccagtgagtggtctgggaaatgctcctatcccattgcagcaggccagagca ttgctggatgaagtgcagcttaaagagaaagttctcctaaggcaacaaggcagttatatc ctgactgtggaagctgggaagcaattgctgctctctgctgacagtggagctgaagcagcc ctgcaggcagagcttacagaaattcaggagcaatggaagaaagttagcacccaactggaa gaacagaagaagcaggttgctttattactgaaagactgggaaagatctgaaaagggtata gcagactccctggagaagctaagatcattcaaaaaaaagctttctcagcctttgccagaa caccatgatgagctgaatgcagaacagattcgttgcaaggaattagagaatgctgttgat ggatggacagatgaccttgcacacctctctctgctgaaggagtccttgtctacctatata agtgcagatgatacttcagtcctcagtgagcgtatagagcttctgcacagacagtgggag gagctgtgccatcaggtctctttacgtcgacagcaagttagtgagaaactgaatgagtgg gctgtcttcagcgagaagaacaaggagctctgtgagtggctgacacaaatggaaagtaaa gtttctcaaaatggtgacatcgtcatagaagaaatgatcgagaaacttagaaaggattat caagaggaaattgctgtagcccaagagagcaaaatccagctccagcaaatgggagagcga cttgctaaagccagccatgagagtaaagcatcagagattgagtacaaacttggcaagatc aatgacagatggcaacatcttctggatcttattgcagccagggtaaagaagttgaaagaa acactagttgcagtgcagcagctggataagaacatgagtagcctgagatcttggcttgct cacattgaatcagagctgtccaaaccaattgtctatgaaacttgtgactctgaggagata caaaggaagctaaatgaacagcaggaacttcagagagacatagagaaacacagcactgga gtggcatctgttctcaatttgtgtgaagttcttcttcacgactgtgatgcctgtgccaca gaaacagagtgtgactctatccagcaggctacacgcaatctggacagaaggtggagaaac atttgtgcaatgtcaatggaaaggcgacttaaaattgaagagacgtggcggttatggcaa aagtttttggatgactactctagatttgaagactggctaaaaaactcagagagaacagct gctttcccaagctcctccggtgtgctttacacagttgctaaggaagaactgaagaaattt gaggccttccagagacaggtgcatgaaagtctgactcagctggaactgattaacaaacag tatcgccgactggcccgggagaaccgcactgattccgactgcagcctcaagcagatggtc catgaggggaaccagagatgggacaatttacaaaagcgagttacctccatcctgcgaagg ctaaaacattttattggccagcgtgaggagtttgagacagcacgtgatagcatcctggta tggctaacagagatggacttgcagctgaccaacatagagcatttctcagagtgtgatgtc caagcaaagataaagcaacttaaggctttccaacaagaaatttcactgaacaacaacaaa attcaccagataattgttcagggtgagcaactcattgagaaaagtgaaccgatggatgca gctgtcattgaagaagaactagatgagttacgtcgttactgtcaagaggtctttggacgt gtggaacgctatcacaagaaactgatccatcttcctctgacagatgatgaacatgacctg tctgacagagaggtggatctggatgaatcagcagatctctctgacatacactggcatgac aaatctgcagacagtgttctctccccacatccctcttccaacatctcactgcctcttgca cagccagtgagaagtgagcgatcagggcgggatacccctgcaagtgtggactctatccct ctggagtgggatcatgattatgacctaagcagagacctggagacagctgtttcacgggca ctacactctgaggaggaagatggagaacaagagaaggatttctatctgagaggagcaact agtatagcagatgtagagatccctgaaactcttgaggcctatgtaacacttacagaaaac gcactcaaaaacatttctggagaacctggtgccctagaagcacatatacgacagctggac aaagctttagataccagtcgtttccaaatacagcaaacagaaaacatcatccgcagcaaa acacctacaggaccagagctggatgccacttacaaaggatatatgaagctactaagtgaa tgcagtggaagcatagactcagtaaaaaggcttggatataagctgaaagaagaagaggaa aaattatcaggacttattaatctgaacagtactgaaacacaaacagctggtgtaattgac cgatgggaattaatccaggctcaagctctaagcaaggagctaaggatgaagcagaacctt cagcaatggcagcagttcaattctgaccttaacagcatttgggcttggttaggagaaaca gaggaagaactggagaagctccgccgccttgatctcagtactgacatacaaactatcgag ctcaggattagaaaattgaaagagctgcagaaggcaattgataaccgcaaagctatcatc ttatccatcaacttgtgcagctcagaatttactcaatctgacagtgaagaaagcaaaaaa ctccaagagcgcctgtctcagatgaacatctgctgggatcacgtatgcagtatgatcgaa gattggcgctgctcactgcaagatgcattaatgcagtgccaggatttccatgaaatgagc catggtttgctgctctggttagagaatattgacagaagaaaaaatgagattgtgcccatc aatccaaacctggattcagaaatcctacaggatcatcacagacttctaatgcaaatcaga cgtgaactgctggaatctcagttgaaagtggcgtcactgcaagatatgtcctgccaattg ttagtcaatgctgaaggcaaggactgccttgaagccaaagaaaaggtgcatgtcattgga aacagactaaagctcctcttgaaagaagtcatacgtcacataaaagacctagagaaagct ctagacatttcaagtagtcagttggatttgtcctcttggtcctctgctgatgaactagac acatcaggctctgtgagtcctgtatctggacaaagcacaccaagcagacagagaacgcca cggggcaaatgtagtctctcacagcctggaccctctgtcagcagtccacatagcaggtcc ataagagatggctcaggttcctccccttctgaggctgggccagcatggcagcacccatcc ttcttcctccgagtcctcagagctgctctgccactacagctccttttgctgctcctgatc gggctggcttgcctggttccaatgactgaagaggactacagctgtacaatggccaacaac tttgcccgctctttccatcccatgttaaaatacatgaatggtccacccccgttatga

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