Lagopus muta (rock ptarmigan): 125689502 Help Entry 125689502         CDS       T09141                                  Symbol RYR2 Name (RefSeq) ryanodine receptor 2 isoform X1   KO K04962   ryanodine receptor 2 Organism lmut  Lagopus muta (rock ptarmigan) Pathway lmut04020   Calcium signaling pathway lmut04260   Cardiac muscle contraction lmut04261   Adrenergic signaling in cardiomyocytes lmut04371   Apelin signaling pathway Brite KEGG Orthology (KO) [BR:lmut00001]  09130 Environmental Information Processing   09132 Signal transduction    04371 Apelin signaling pathway     125689502 (RYR2)    04020 Calcium signaling pathway     125689502 (RYR2)  09150 Organismal Systems   09153 Circulatory system    04260 Cardiac muscle contraction     125689502 (RYR2)    04261 Adrenergic signaling in cardiomyocytes     125689502 (RYR2)  09180 Brite Hierarchies   09183 Protein families: signaling and cellular processes    04040 Ion channels [BR:lmut04040]     125689502 (RYR2)    04990 Domain-containing proteins not elsewhere classified [BR:lmut04990]     125689502 (RYR2) Ion channels [BR:lmut04040]  Voltage-gated cation channels   Ryanodine receptor    125689502 (RYR2) Domain-containing proteins not elsewhere classified [BR:lmut04990]  EF-hand domain-containing proteins   Other EF-hand domain-containing proteins    125689502 (RYR2) BRITE hierarchy SSDB OrthologParalogGene clusterGFIT Motif Pfam:  RYDR_Jsol RYDR_ITPR RyR RR_TM4-6 SPRY MIR Ins145_P3_rec RIH_assoc Ion_trans EF-hand_7 EF-hand_1 EF-hand_8 EF-hand_6 Motif Other DBs NCBI-GeneID:  125689502 NCBI-ProteinID:  XP_048792668 LinkDB All DBs Position 2:72903168..73245395 Genome browser AA seq 4994 aa AA seqDB search MAEGGEGEDEIQFLRTSYSLTIGTTSRAWEAHFVVDDEVVLQCTATVHKEQQKLCLAAEG FGNRLCFLESTSNSKNVPPDLSICTFVLEQSLSVRALQEMLANTEEKAEGLVDVEKWKFM MKSAQGGGHRTLLYGHAILLRHSYSGMYLCCLSTSRSSMDKLAFDVGLQEDTTGEACWWT IHPASKQRSEGEKVRVGDDLILVSVSSERYLHLSYGNGSLHVDAAFQQTLWSVAPISSGS EFAQGYLIGGDVLRLLHGHMDECLTVPSGEHGEEQRRTVHYEGGAVSIHARSLWRLETLR VAWSGSHIRWGQPFRLRHITTGKYLSLLDDKSLLLTDKEKADVKSTAFCFRSSKEKLDVG VRKEVDGMGAPEIKYGDSICFIQHVDTGLWLSYQSADAKSVRMGSVQRKAIMHHEGHMDD GLTLSRSQHEESRTARVIRSTVFLFNRFIRGLDALSKKMKSSAVDLPIESVSLSLQDLIG YFHPPDEHLEHEDKQNRLRALKNRQNLFQEEGMINLVLECIDRLNVYSSAAHFADVAGKE AGEAWKSILNSLYELLAALIRGNRKNCAQFSGSLDWLISRLERLEASSGILEVLHCVLVE SPEALNIIKEGHIKSIICLLDKHGRNHKVLDVLCSLCVCHGVAVRSNQHLICDNLLPGRD LLLQTRLVNHVSSMRPNIFLGISEGSAQYRKWYYELMVDHLEPFVTAESTHLRVGWASTE GYSPYPGGGAEWGGNGVGDDLYSYGFDGLHLWSGCVARTVNSPNQHLLRTEDVISCCLDL SAPSISFRINGQPVQGMFENFNIDGLFFPVVSFSAGIKVRFLLGGRHGEFKFLPPPGYAP CFEAVLPKEKLKVEHSREYKQDRSYTRDLLGPTLNLSQAAFTPVPVDTSQIVLPPHLERI REKLAENIHELWVMNKIELGWQYGPVRDDNKRQHPCLVEFSKLPEQERNYNLQMSLETLK TLLALGCHVGIADERAEEKVKKMKLPKNYQLLSGYKPAPMDLSFIKLTPSQEAMVDKLAE NAHNVWARDRIRQGWTYGIQQDVKNRRNPRLVPYALLDDRTKKSNKDSLREAVRTLLGYG YNLEAPDQDHATRLDVSNGIMEKFRIFRTEKTYAVKSGKWYFEFEAVTAGDMRVGWTRPG CLPDQELGSDEEAFVFDGFKAQRWHQGNEHFGRSWLAGDVVGCMVDMNEHTMMFTLNGEI LLDDSGSELAFKDFEVGDGFLPVCSLGSSQVGRMNFGKDVSTLKYFTICGLQEGYEPFAV NTNRDITIWLSKRLPQFLPVPQNHEHIEVMRIDGTIDTCPCLKVTQKSFGSQNSKTEVMF FRLSMPIECAEVFSRTAAGGLPGTGLFGPKNDLEDYDADSDFEVLMKTAHGHLAADRTER EKDATKPELNNHKDFVQEKPSRLKQRFMLRRTKPDYSTSHSARLTEDVLADDRDDYDYLM QTSTYYYSVRIFPGQEPANVWVGWITSDFHQYDTNFDLDRVRTVTVTLGDEKGKVHESIK RSNCYMVCAGESMSPGQGRNNNGLEIGCLVDAASGLLTFTANGKELGTYYQVEPSTKLFP AVFAQATSPNVFQFELGRIKNVMPLSAGLFKSEHKNPVSQCPPRLHVQFLTHVLWSRVPN HFLKVDVSRISERQGWMIQCLNPLQFMALHIPEENRTIDILELTEQEELLKFHYHTLRLY SAVCALGNNRVAHAMCSHVDESQLLYAIENKYMPGLLRAGYYDLLIDIHLNTYATARLMM NNEFIVPMTDETKSITLFPDENKKHGLPGIGLSTSLRPRMQFSSPSFVSINSECFQFSPE FPLEILKAKTIEMLTEAVQEGSLHVRDPVGGSTEFLFVPLIKLFYTLLIMGIFHNGDLKH ILQLIEPRVFKEAVNLEDERDLSEKELSSDDLKSEGEEETRGEQVPKEGLLQMKLPEPVK LQMCHLLQYLCDCQVRHRIEAIVAFSDDFVAKLQENQRFRYNEVMQALNMSAALTARKTK EFRSPPQEQINMLLNFKDDKTDCPCPEEIRDQLLDFHEDLMTHCGIELDEDGTLDGNSDL TIRGRLLYLMEKVTYLKKKQAEKPIDDDAKTSSTLQQLISDTMVRWAQESVIEDPELVRA MFVLLHRQYDGIGGLVRALPKTYTINSVSVEDTINLLASLGQIRSLLSVRMGKEEEKLMI RGLGDIMNNKVFYQHPNLMRALGMHETVMEVMVNVLGGGESKEITFPKMVANCCRFLCYF CRISRQNQKAMFDHLSYLLENSSVGLASPSMRGSTPLDVAAASVMDNNELALALREPDLE KVVRYLAGCGLQSCPLLISKGYPDIGWNPVEGERYLDFLRFAVFCNGESVEENANVVVRL LIRRPECFGPALRGEGGNGLLAAMEEAIQISEDPTRDGPSPINGSSRTLEIEEQEDDTIH MGNAIMTFYAALIDLLGRCAPEMHLIHAGKGEAIRIRSILRSLIPLEDLVGVISIPFHMP TIAKDGTVVEPDMSAGFCPDHKAAMVLFLDRVYGIEDQDFLLHLLEVGFLPDLRAAASLD TAALSATDMALALNRYLCTAVLPLLTRCAPLFAGTEHHASLIDSLLHTVYRLSKGCSLTK AQRDSIEECLLSICGQLRPSMMQHLLRRLVFDVPLLNEHAKMPLKLLTNHYERCWKYYCL PGGWGNFGAASEEELHLSRKLFWGIFDALSQKKYEQELFKLALPCLSAVAGALPPDYMES NYVNMMEKQSSMDSDGNFNPQPVDTSNITIPEKLEYFINKYAEHSHDKWSMEKFANGWTY GETYSESAKVQPLMKQYKLLSEKEKEIYRWPIKESLKTMLAWGWRIERTREGDSMALYNR TRRISQTSQISVDAAHGYSPRAIDMSNVTLSRDVHAMAEMMAENYHNIWAKKKKMELEAK VGGGNHPLLVPYDTLTAKEKAKDREKAQDILKFLQINGYVVSRGLKDLELDTPSIEKRFA YSFLQQLIRYVDEAHQYILEFDGGSRGKGEHFPYEQEIKFFAKVVLPLIDQYFKNHRLYF LSAASRPLSSGGHASNKEKEMVTSLFCKLGVLVRHRISLFGNDATSIVNCLHILGQTLDA RTVMKTGLESVKMALRAFLDNAAEDLEKTMENLKQGQFTHSRNQPKGVTQIINYTTVALL PVLSSLFEHIGQHQFGEDLILEDVQVSCYRILSSLYALGTSKSIYVERQRSALGECLAAF SGAFPVAFLETHLNKHNIYSIYNTKNARDRAVLNLPTSVEEVCPNIPSLVKLMEEIVELA ESGIRYTQMPHIMEVILPMLCSYMSHWWEHGPENNPDKAEVCCTALTSEHMNTLLGNILK IIYNNLGIDEGAWMKRLAVFSQPIISKAKPQLLKTHFLPLMDKLKKKAAVVVSDEEHLRA EGRGDMSEAELLILDEFTTLARDLYAFYPLLIRFVDYNRAKWLKEPNPEAEELFRMVAEV FIYWSKSHNFKREEQNFVVQNEINNMSFLISDTKSKMSKAAVSDQERKKMKRKGDRYSMQ TSLIVAALKRLLPIGLNICAPGDQDLIALAKNRFSMKDTEDEVRDIIRSNLHLQGKLEDP AIRWQMALYKDLPNRTEDSSDPEKTVERVLDIANVLFHLEQRSACVGRGYFFWVEHPQRS KKAVWHKLLSKQRKRAVVACFRMAPLYNLPRHRAVNLFLQGYDKSWIETEEHYFEDKLIE DLAKPGEEPPEEDESLKRVDPLHQLILLFSRTALTEKCKLDEDFLYMAYADIMAKSCHDE EDDDCEEEVKSFEVTGSQRSKEKEMEKQKLLYQQARLHDRGAAEMVLQTISASKGEMGPM VAATLKLGIAILNGGNSTVQQKMLDYLKDKKDVGFFQSLAGLMQSCSVLDLNAFERQNKA EGLGMVTEEGSGEKVMQDDEFTCDLFRFLQLLCEGHNSDFQNYLRTQTGNNTTVNIIIST VDYLLRVQESISDFYWYYSGKDVIDEQGQRNFSKAIQVAKQVFNTLTEYIQGPCTGNQQS LAHSRLWDAVVGFLHVFAHMQMKLSQDSSQIELLKELMDLQKDMVVMLLSMLEGNVVNGT IGKQMVDMLVESSNNVEMILKFFDMFLKLKDLTSSDAFKEYDPDGKGIISKRDFHKAMES HKHYTQSETEFLLSCAETDENETLDYEEFVKRFHEPAKDIGFNVAVLLTNLSEHMPHDTR LQTFLELSESVLNYFQPFLGRIEIMGSAKRIERVYFEISESSRTQWEKPQVKESKRQFIF DVVNEGGEKEKMELFVNFCEDTIFEMQLAAQISESDLNERSANKEDNEKDKPEEQDPGMG FFSLVTMKSALVALKYNLMTLMKMLSMKSLKKQMKKVKKMTMKDMVMALFSSYWSILMGL LHFACSVFRGFFRIICSLLLGGSLVEGAKKIKVAELLANMPDPTQDEVRGEGEEGERKPA ETALPAEDLTDLRTLSEESDLLSDIFGLDLKREGGQYKLIPHNPNAGLSDLLSTPSIAPM PEAQEKVQEQVKEDEKEEKEETKSEPEKAEGEDGEKEEKAKEDKAKQKLRQLHTHRYGEQ EIQESAFWKKIIAYQQKLLNYFARNFYNMRMLALFVAFAINFILLFYKVSTSAVIEEKEI PVVSTGENMKLDSLESDSQRVIAVHYVLEESSGYMEPTLRILAILHTVISFFCIIGYYCL KVPLVIFKREKEVARKLEFDGLYITEQPSEDDIKGQWDRLVINTQSFPNNYWDKFVKRKV MDKYGEFYGRDRISELLGMDKAALDFSDAREKKKPKKDSSLSAVLNSIDVKYQMWKLGVV FTDNSFLYLAWYMTMSVLGHYNNFFFAAHLLDIAMGFKTLRTILSSVTHNGKQLVLTVGL LAVVVYLYTVVAFNFFRKFYNKSEDGDMPDMKCDDMLTCYMFHMYVGVRAGGGIGDEIED PAGDEYEIYRIIFDITFFFFVIVILLAIIQGLIIDAFGELRDQQEQVKEDMETKCFICGI GNDYFDTVPHGFETHTLQEHNLANYLFFLMYLINKDETEHTGQESYVWKMYQERCWEFFP AGDCFRKQYEDQLN NT seq 14985 nt NT seq  +upstreamnt  +downstreamnt atggccgaggggggcgagggcgaggacgagatccagttcttgagaactagttacagtttg acaattggaaccacatctagagcttgggaagcacactttgttgtagatgatgaagtggtt ctgcagtgcactgcaactgttcacaaggagcaacagaaattgtgtcttgctgcagaagga tttggcaacaggctttgctttttggaatccacgtcaaattctaagaatgtgccacctgac ttgtccatctgcacctttgtgcttgagcagtctctgtcagtacgagccctgcaggaaatg ctggctaacacagaggagaaggcagaagggctagttgatgtggaaaaatggaaatttatg atgaagtctgcacagggtggtggtcatcgaacgcttctctatggacatgcaatcctgctg cgccattcctacagtggtatgtatctgtgctgcctctcaacatctcgatcttcaatggat aagctggcatttgatgtaggattgcaagaggacaccacaggtgaggcatgctggtggact attcatcctgcttctaagcagcgatcagaaggagaaaaagtgcgtgttggagatgacctt attttagtcagtgtctcttctgaaagatacttgcatctctcctatggcaatggtagctta catgttgatgcagctttccaacagactctttggagtgtagcaccaatcagttcaggaagt gaatttgcccaaggatatctgataggtggggatgttctgaggttgttgcatggtcatatg gatgaatgcttgacagtcccttcgggtgaacatggagaagaacaaaggagaactgtccat tatgaaggtggtgcagtgtcaattcatgctcgttccctttggcgattagaaactctgaga gttgcgtggagtggcagccacataagatggggacagccattcagactaagacatataaca acaggaaaatatttaagtctactggatgacaagagtcttctccttactgacaaagagaaa gcagatgtaaaatctacagcattctgttttcggtcctccaaggaaaaactggatgttggt gtgagaaaagaggtagatggaatgggagcacctgaaataaaatatggagattcaatatgc ttcatacaacatgtagacacaggcttgtggctgtcataccagtctgcagatgcaaagtct gtaagaatgggttctgtgcaacgcaaggcaataatgcaccatgaaggtcacatggatgat ggtttaacattgtccagatctcagcacgaagaatcccgtacagcacgtgtcatccgtagt acagtcttccttttcaacaggtttataaggggccttgatgctctcagcaaaaaaatgaag tcttccgcagtagatttacctattgagtctgtcagtctgagccttcaagacttgattgga tactttcaccctcctgatgaacatttagagcatgaagacaagcaaaacaggctccgtgca ctgaagaatcgccagaatctcttccaggaagagggcatgatcaacctcgttcttgaatgt attgatcgcttgaatgtatacagcagtgcagctcattttgcagatgtagctgggaaggaa gctggagaagcatggaaatcaattctgaattccttgtatgaattactagcggctcttatt cgagggaatcgtaaaaactgtgctcagttttctggatctcttgattggctgatcagcaga ttagaaagactagaagcctcttctggaatactagaagttttacactgtgtattggtggaa agccctgaagctctaaacattattaaggaaggacatattaaatcaatcatctgtcttttg gacaaacatggaagaaaccataaggttttggatgtcttatgttctctctgtgtatgtcat ggagtggctgtgcggtccaatcaacatctcatctgtgataatctcctgccaggaagagat ctgctcttacagacccgccttgtcaaccatgtgagcagcatgcgacctaatattttcttg ggaattagtgaaggctctgcccagtacagaaaatggtactatgaacttatggtggaccat ctagagccttttgtgactgcagaatcaactcacctacgagtaggctgggcttcaacagag ggctactcaccttatccagggggaggagcagaatggggaggaaatggtgttggtgatgac ttgtattcttatggctttgatggtctgcatctgtggtcaggctgtgtagctcgaacagta aattctccaaaccaacatctgttaagaactgaagatgttattagttgttgtttggatctg agtgcccccagcatctcttttcgtataaatggacagccagttcaaggaatgtttgagaat ttcaatatagatggccttttcttcccagttgtcagcttctctgcaggaataaaggtacgc ttcttgcttggaggtcgtcatggagaattcaagttccttcctccacctggatatgcccct tgctttgaagctgttctaccaaaagagaaactgaaagtggagcatagccgagaatacaag caggatcgaagctatacgagagatcttctgggtcccactctcaatctgtcacaagcagct ttcaccccagttcctgtagatactagccagattgttttgcctccccacttggaaagaatt agagaaaagttagcagagaacatccatgaactttgggttatgaataagattgaactgggc tggcagtatggaccagttagagatgacaacaaaagacagcacccatgcttagtggagttc tcaaaattgccggagcaggaaagaaattataacttacaaatgtctcttgaaacactaaaa accctgctggcgttaggctgccatgttggaattgctgatgaacgtgctgaagaaaaagtg aaaaaaatgaaacttccaaagaactaccagttgttgagtggatataagcctgctcccatg gatctgagcttcatcaaactgaccccctctcaagaagctatggtggataaactagcggag aatgctcacaatgtatgggcaagagaccgaatcaggcaaggctggacctatggtatccag caggatgtgaaaaatcgacgaaatcctcgccttgtaccttatgcccttttggatgatcga acaaagaagtcaaacaaagacagccttcgggaagcagtccgcacccttctaggctatggg tacaacctggaagctcctgaccaagatcatgcaacaagactggatgtcagcaatgggata atggaaaaattccggatcttccgcacagagaaaacttacgcagtgaaatctggaaagtgg tactttgagtttgaggcagttacagcaggagacatgagagttggctggacgaggcctggt tgtctgccagatcaggaacttggctcagatgaagaagcttttgtttttgatggctttaag gcacagcggtggcatcaaggtaatgagcattttggccgctcctggttggcaggagatgtt gttggatgcatggttgacatgaatgaacacactatgatgttcaccttaaatggtgaaatc ctgcttgatgactcaggttcagaacttgcatttaaggattttgaggttggtgatggattt ttacctgtgtgcagcctgggttcatctcaagtgggaagaatgaactttggaaaagatgtc agcactctaaaatatttcactatctgtggattacaggaagggtatgaaccctttgctgtt aatacaaacagagacattaccatttggctgagtaaaaggctccctcagtttcttccagtg ccacaaaatcatgaacatattgaggtgatgagaattgatggaaccatagacacttgtcct tgcctgaaggttacacagaagtcctttggttcacagaacagtaaaacagaagtcatgttt tttcggttaagtatgcccattgaatgtgctgaggtgttctccagaacagctgcaggaggg ctaccaggcactggtctttttggcccaaagaatgatttggaggattacgatgctgattct gattttgaagttttaatgaaaactgctcatggtcatctagcagctgaccggacagagaga gaaaaggatgccacaaaaccagagttaaataaccataaagattttgttcaagaaaagcct tcacgtcttaaacaaagatttatgcttaggaggacaaaaccagattatagcacgagccat tccgcaaggcttactgaggatgtactagcagatgatagggatgactatgattatttgatg caaacttccacgtactattactcagtgagaatatttcctggtcaagaacctgctaatgtt tgggtaggctggattacgtctgactttcatcagtatgacacaaactttgacttggacaga gtgcgtactgttacagtaacactgggagatgaaaaaggaaaggtccatgagagtataaaa cgcagcaactgctatatggtatgcgcaggagagagcatgagtcctgggcaaggacgtaat aataatggtctggagattggttgcttagttgatgctgccagcggcctgctgaccttcacg gctaatggcaaagaactgggcacatactatcaggttgaaccaagtacaaagttatttcct gctgtatttgctcaggctacaagcccaaatgttttccagtttgagttgggtagaattaag aatgtaatgccattatctgctggcttattcaaaagtgaacacaaaaacccagtctcccag tgtcctccacgtctccatgtccaatttctgactcacgtgctttggagtagagtgccaaac cacttcttgaaagttgatgtctctaggatcagtgaacgtcagggctggatgatacaatgc ctgaatcctttgcagttcatggcccttcacattcctgaagaaaacagaacaattgatatt ttagagctgacagaacaagaagaactgctgaaatttcactaccatactctccgattatat tcagctgtatgtgctttagggaacaaccgagtggcccatgctatgtgtagccatgtggat gaatctcagcttctgtatgctattgagaataaatatatgccaggattattgcgtgcagga tattatgacttactcatagacatccatctcaatacctatgcaactgccaggttaatgatg aataatgaatttattgttccaatgactgatgagaccaagagtattaccttgtttcctgat gagaacaagaaacatggcctgcctggtataggactcagcacttccttaaggccaagaatg cagttctcctcaccgagttttgtaagcattaacagtgaatgctttcagtttagtcctgaa ttcccgctagaaatcttgaaggccaaaacaatagagatgctgactgaagctgttcaggag ggcagcctccatgtcagagacccagttggaggttctacagaatttctgtttgtccccctc atcaagctcttttacaccctcctaattatgggaatcttccacaacggggatctgaaacac attttacagttaattgagccacgggttttcaaagaagctgtgaatctggaggatgaaagg gatctctcagagaaggagctgagttcagatgatctcaagtcagaaggagaggaagaaacc agaggagagcaagtgccaaaggaaggactccttcaaatgaaacttcctgagcctgttaaa ctacagatgtgtcatctactccagtacctgtgtgattgccaggtacgacaccgaatagaa gccattgtagcattttcagatgattttgtggccaagcttcaagagaatcagcgcttccgg tacaatgaagtgatgcaggccttaaacatgtctgctgccttgacagctagaaaaacaaag gaatttcgatccccacctcaggagcagattaacatgctgctgaactttaaagatgataaa actgattgtccttgccctgaagaaattagggatcaactcttggatttccatgaagaccta atgacacactgtggaattgaactggatgaagatggaactttggatggaaatagtgattta actattaggggtcgcctcctatacctaatggaaaaagttacatatctgaagaagaagcaa gctgagaagccaattgatgatgatgctaagacatcctctactcttcagcaattgatttca gatacaatggtgcgctgggcccaggaatcagtaatagaagacccagagttagtcagggcc atgtttgtactgctccatcgccagtatgatggtatcggtggcttggttcgagccctacca aagacttacaccataaatagtgtgtccgtggaagatacaatcaatctcctggcatccctt ggccaaatccgttcattgctcagtgtcaggatggggaaggaggaagagaaacttatgatt cgtggattaggagacatcatgaataataaagtattttatcaacatcccaatctcatgaga gctttaggcatgcatgagaccgtcatggaagtgatggtaaatgtacttggtggaggagaa tccaaggaaatcactttcccaaaaatggtggcaaactgctgtcgtttcctatgttatttt tgccgcattagtaggcagaatcaaaaagctatgtttgatcatcttagctatttattggaa aatagcagtgttggccttgcctctccttctatgcgaggatcaactcctttagatgttgca gcagcatctgtaatggataacaatgaacttgcattagctttaagggagcctgatctggag aaggtggttcgatacttggctggatgtggattgcagagttgtcctttgttgatttctaaa ggctatccagacattggatggaatccagttgaaggagagagatatttggattttcttcgt tttgctgtattttgcaatggagagagtgtggaggaaaatgctaatgttgtagtcagactg cttattcgtcgaccggaatgttttggtccagctctaagaggagaaggaggcaatggtcta cttgctgccatggaggaagcaatacaaatatcagaagatccaacaagagatggaccttcc ccaattaatggatctagtagaacccttgaaatagaagaacaagaagatgatactattcat atggggaatgcaatcatgacgttttatgctgctttgattgatctcttaggacgttgtgcg cctgaaatgcatctaatacatgctggtaaaggggaggccataagaatccggtcaattcta aggtctttgattccactggaagatttggtgggcgtaattagcattccattccacatgcca accatagctaaagatggtactgtggtggaacctgacatgtctgcggggttttgcccagat cacaaggcagccatggttttgttccttgacagggtctatggaattgaggatcaggatttt cttctacatcttcttgaagttggctttctgccagatctccgtgccgctgcttctttagat acagctgcattaagtgctacagatatggctttagctctgaatcgatacctttgcacagca gtcttgcctctgttgaccagatgcgctcctctttttgctggcacagagcaccatgcttcc cttattgattccttactacatactgtgtacagactttcaaagggctgctctcttaccaaa gctcagcgagattccattgaggagtgtttactttctatctgtgggcagttgagaccttct atgatgcagcacttgctgagaagattagtatttgatgttcccctattaaatgaacatgca aagatgcctctcaagttgctgacaaatcattatgaaagatgctggaagtattattgttta ccaggtggatggggtaactttggtgctgcctcagaagaagaacttcatttatccagaaag ttgttctggggtatttttgatgctttgtctcaaaagaagtatgaacaagaactgttcaag ctggctttgccttgtttgagtgcagttgcaggggcattacctccagattatatggaatca aattatgtcaatatgatggaaaaacaatcttcaatggattcagatggaaacttcaatccc caacctgttgatacttcaaacattacaatccccgaaaaactagaatatttcattaacaaa tatgcggaacactctcatgataagtggtcgatggaaaagtttgccaatggatggacatat ggtgaaacgtattctgaatctgcaaaagtgcaaccattaatgaaacagtataaattactc tctgaaaaggagaaagaaatttatcgatggccaatcaaagaatcactaaagaccatgctg gcatggggatggcggattgaaaggacacgggagggagattccatggcattgtataatcgg acgcgtcgcatatctcaaaccagtcaaatctctgtggatgcagcccatggttacagtcct cgagcaattgacatgagcaatgttaccctctccagagatgtgcacgctatggcagagatg atggctgaaaactaccataacatatgggcaaagaaaaagaaaatggagcttgaagcaaaa gtaggaggaggaaaccatccccttcttgttccttatgatacactcacagccaaggaaaaa gctaaggacagagaaaaagcacaggatattctgaaatttctacagattaatggatatgta gtctccagaggacttaaggacctggaattggacacaccttccattgagaaacgctttgcc tacagtttcctccagcagcttataagatatgtagatgaagctcatcagtacattttggaa tttgatggtggcagcagaggcaaaggagagcatttcccatatgaacaagaaatcaagttt tttgccaaagttgtgctccctttgattgatcagtatttcaaaaatcatcgcttgtatttc ttatctgcagcaagtaggcctctcagcagtggaggccatgcctctaataaggagaaagaa atggtgacgagcctgttctgcaaacttggagttcttgtcaggcataggatttcactgttt ggaaatgatgcaacatcaatagtcaactgtcttcacatattgggccagaccttggatgcc agaactgtgatgaaaactggtctggagtctgttaagatggcattgagagcatttttggac aatgctgctgaggatctggagaaaacaatggaaaatcttaagcaaggccagtttacacac agcagaaaccagcccaagggagttacacaaatcattaattataccacagtggctctcctt ccagtgctatcttcattatttgaacatattggacagcaccagtttggggaagatttgata ttggaagatgttcaagtgtcttgttacagaatattgtccagtttgtatgcactgggaacc agcaaaagtatatacgtagagcggcaacgatcagcattaggagaatgcttggctgctttc tcaggtgcctttccagtggcttttttggaaactcacttgaacaaacataatatctactca atttacaataccaagaatgcaagagacagagcagttcttaatttacctactagcgtagaa gaagtttgcccaaatattccttccttggtgaagctaatggaagaaattgtggaactggca gaatctggtattcgctacacacaaatgccacacataatggaagttatactgcctatgctt tgtagttacatgtcacactggtgggagcatgggccagaaaacaatcctgacaaagctgaa gtgtgttgtacagccttgacatcagagcacatgaacactcttttgggtaacatattgaaa atcatctataacaaccttggtattgatgaaggagcctggatgaagaggttagcagtgttt tcccagcccatcataagcaaagcgaagccacagctcttaaagacacacttcctgccactg atggataagctaaagaaaaaagcagcagtggttgtatcggatgaagagcatctaagagca gaaggcagaggtgacatgtcggaggctgaactgctcatcctagatgagttcaccactttg gcacgggacctctatgccttctaccctttgttgattagatttgtggactataacagggca aaatggctgaaagaacccaaccctgaagctgaagaattgttccgcatggtggctgaagtc tttatttactggtcaaagtctcataatttcaaaagggaagaacagaactttgtggtacaa aatgaaatcaacaacatgtccttccttattagtgacaccaaatctaagatgtccaaggca gcagtttctgatcaagagaggaagaagatgaagcggaaaggtgaccggtactctatgcag acctctctcattgtggcagcactgaagagattacttcctattggtctaaatatttgtgct cctggagaccaagatctaattgcactggccaaaaaccgattcagcatgaaagatactgag gatgaggtacgagatatcattcgcagtaatcttcatctccagggcaagctcgaggatccc gccattagatggcagatggcactttacaaagatttacctaacaggactgaagattcatca gatccagagaagactgtggaaagagttcttgatatagctaatgtactgtttcatctggaa cagagatctgcttgtgtaggccgaggctatttcttctgggttgaacatcctcagcgttcc aaaaaagcagtttggcataaactgctgtctaaacagaggaaaagagcagtagttgcttgc tttagaatggcaccattgtataacttgccaaggcaccgagctgtcaatctctttcttcaa ggatatgacaaatcttggattgaaacagaagaacactattttgaagacaaactgatagaa gatttagcaaaacctggagaggaaccaccagaagaagatgaaagccttaaaagagttgat ccattgcatcaactgattctactgttcagtcgaacagccttaacagaaaaatgcaaattg gatgaagattttctgtatatggcttacgctgacataatggcaaagagttgccatgatgaa gaagatgatgattgtgaagaagaagtgaagagctttgaagtcacaggatcccaacgcagc aaggaaaaagaaatggaaaagcaaaaacttctgtatcagcaagccagactgcatgaccgg ggtgctgctgagatggttcttcagacaatcagtgctagtaaaggtgagatgggaccaatg gttgcagctaccctgaaacttgggattgccatcttaaatggaggaaattctactgttcag cagaaaatgcttgactacctcaaggataagaaagacgtgggtttctttcagagtcttgct ggtcttatgcagtcctgtagtgttcttgatctaaatgcatttgaacgtcaaaacaaagca gaaggccttggcatggtgactgaagagggatcaggagaaaaggtgatgcaggatgatgag ttcacctgtgacctctttcgctttcttcaattgctttgtgaaggacacaattcagatttt cagaattacctgagaactcagactggtaacaacacaactgttaatattatcatttccact gtggattacttattgagagttcaggagtcaattagtgatttctactggtattattctggg aaggatgttattgatgaacaagggcaacgaaatttttccaaagccatccaggttgcaaaa caagttttcaatactctcacggagtacatccaggggccatgtactgggaatcagcaaagt ctggcacacagcaggctatgggatgctgtagttggttttcttcatgtatttgctcacatg cagatgaagctgtctcaggattccagtcaaattgaattactgaaagaattaatggatctt cagaaggatatggttgtcatgttgctgtctatgctggaaggtaatgttgtgaatggaact atcggcaagcaaatggttgatatgcttgtggaatcgtccaacaatgtggagatgattctg aagttttttgatatgttcttaaaactgaaggatttgacttcttctgatgcattcaaagag tatgatcctgatggcaaaggcataatttcaaaaagagattttcacaaggcaatggaaagc cataagcattacacccagtctgaaactgaatttctactatcatgtgctgaaacagatgag aatgagactctggactatgaggagtttgtgaaacgattccatgagcctgccaaagacatt ggtttcaatgtcgctgttctcctgaccaacctctccgaacacatgccccatgatactcgc ttgcaaacttttcttgaactgtcagaaagtgtgctgaactactttcagcctttccttgga cgtatagaaatcatgggcagtgcaaagcgcattgaacgagtgtattttgaaataagtgaa tcaagtcggactcagtgggaaaaacctcaggtaaaagagtcaaagagacagttcatattt gatgttgtaaatgaaggtggggagaaagaaaagatggagctttttgttaatttctgtgaa gacaccatctttgaaatgcaactggctgcccaaatctctgagtcagatctgaatgaaagg tcagcaaataaagaggacaatgagaaagataagcctgaggaacaggatcctggaatgggt ttcttctcacttgtaactatgaagtcagcattagtagcgcttaagtataatttaatgact cttatgaaaatgctcagcatgaagagcttaaaaaaacagatgaaaaaagtgaagaaaatg accatgaaggacatggttatggctttattttcttcctactggagcattttaatgggctta ctgcattttgcctgtagtgtcttccggggcttctttcgcatcatttgcagtttgctgctt ggaggaagcctagtagaaggagcaaagaaaatcaaggtggctgagctattagccaatatg ccagatcccactcaggatgaggtgcgtggtgaaggagaagagggggagaggaagccagca gaaactgcattgcctgctgaagacttgactgatttgagaactttatcagaggagagtgat ctactctcagatatatttggtttggatttgaaacgagaaggtggacagtataaattgatt cctcacaacccaaatgctggtttgagtgatttactgagcactccttccatagcgccaatg cctgaggcacaggaaaaagtccaggaacaggtgaaagaagatgaaaaggaagagaaggaa gaaacaaaatctgaacctgaaaaagcagaaggagaggatggagaaaaagaagagaaagca aaggaagacaaagcaaaacagaaattaagacagcttcatactcacagatatggagaacaa gaaattcaggaatcagctttctggaagaaaatcattgcatatcaacagaagcttcttaac tattttgctcgaaacttttataacatgaggatgttggcattgtttgttgcctttgccatc aacttcatcctgcttttctataaggtctccacctctgctgtgatagaagaaaaggaaatt cctgtagtgtctactggagaaaatatgaagttggacagcttagagagcgacagccagagg gtcattgcagtgcattatgtcctggaagaaagcagtggctacatggaacccacgctgcgg attttggccatcttacatacggtcatctccttcttctgcatcattgggtattactgtttg aaagtcccactagtaatttttaagagagaaaaggaagtagcaaggaagttggaatttgat gggctgtatatcactgaacagccctcagaagatgatattaaagggcaatgggatagactt gtaatcaacacacagtcttttccaaacaactactgggacaaatttgtgaaaagaaaggtc atggataaatatggtgagttctatggccgtgacagaatcagtgagttactaggaatggac aaagctgctctggattttagtgatgctcgagaaaagaagaaaccaaagaaggatagctcc ttatctgctgtgctaaactccattgacgttaagtatcagatgtggaaattaggagttgtt ttcactgataattctttcctttacctagcttggtacatgaccatgtcagtccttggccac tacaacaattttttctttgctgctcatctccttgacattgcaatgggattcaagacatta cgaactatactctcatcagtcacccacaatggcaaacagcttgtcctaacagtgggatta ctggcagtagtggtatacttgtacacagtagtggcattcaattttttccgaaagttctac aacaaaagtgaagatggtgatatgccagatatgaaatgcgatgatatgctaacatgctac atgtttcacatgtatgttggagtgcgtgcaggtggaggcattggtgatgaaatagaggat ccagcaggagatgaatatgaaatctatcgaattatctttgacatcactttcttctttttt gtgattgttatcctgcttgccattattcaagggttaattattgatgcttttggtgagtta agagatcaacaagaacaagttaaggaagacatggagacaaagtgctttatctgtggaata ggaaatgactactttgatacagtgccccatggctttgaaactcatacactgcaggagcac aacttggccaattatttgttttttctgatgtatcttattaacaaagatgaaacggaacat acaggacaggaatcttatgtatggaaaatgtatcaagaacgatgctgggagttttttcct gctggtgattgtttccgaaaacagtatgaagaccagcttaattaa

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