Lagopus muta (rock ptarmigan): 125689581
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Entry
125689581 CDS
T09141
Symbol
GCLC
Name
(RefSeq) glutamate--cysteine ligase catalytic subunit isoform X1
KO
K11204
glutamate---cysteine ligase catalytic subunit [EC:
6.3.2.2
]
Organism
lmut
Lagopus muta (rock ptarmigan)
Pathway
lmut00270
Cysteine and methionine metabolism
lmut00480
Glutathione metabolism
lmut01100
Metabolic pathways
lmut01240
Biosynthesis of cofactors
lmut04216
Ferroptosis
Module
lmut_M00118
Glutathione biosynthesis, glutamate => glutathione
Brite
KEGG Orthology (KO) [BR:
lmut00001
]
09100 Metabolism
09105 Amino acid metabolism
00270 Cysteine and methionine metabolism
125689581 (GCLC)
09106 Metabolism of other amino acids
00480 Glutathione metabolism
125689581 (GCLC)
09140 Cellular Processes
09143 Cell growth and death
04216 Ferroptosis
125689581 (GCLC)
Enzymes [BR:
lmut01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.2 glutamate---cysteine ligase
125689581 (GCLC)
SSDB
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Paralog
GFIT
Motif
Pfam:
GCS
GCS2
SANT_DAMP1_like
Motif
Other DBs
NCBI-GeneID:
125689581
NCBI-ProteinID:
XP_048792907
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All DBs
Position
2:complement(22790888..22822992)
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AA seq
635 aa
AA seq
DB search
MGLLSQGSPLSWEETRRYAEHVRKHGILQFLHIYRALRDRHKDVLKWGDEVEYMLVKFDH
ENKKVRLVLSGEEVLQTLQDKGEKINPNHPTLWRPEYGSYMIEGTPGQPYGGTMSEFNTV
QDNMRKRRQEAASVLKENEAICTVTSFPRLGCPGFTLPEYKPTPVEGGASKSLFFPDEAI
NKHPRFSTLTRNIRHRRGEKVVINVPIFKDKNTPSPFIETFPNDDGEAAKAAKPDFIYMD
AMGFGMGNCCLQVTFQACSISEARYLYDQLATICPIVMALSAASPFYRGYVSDIDCRWGV
ISASVDDRTREERGLEPLKNNHYRISKSRYDSIDSYLSECGEKYNDIDLTIDKDIYEHLI
KEGIDHLLAQHIAHLFIRDPLTLFEEKIHLDDANESDHFENIQSTNWQTMRFKPPPPNSD
IGWRVEFRPMEVQLTDFENSAYVVFVVLLTRVILSYKLDFLIPLSKVDENMKMAQKRDAV
RQGMFYFRKDICKGGNVVDGCGSAQNGTGTDTEEYTLMSIDTIINGKEGVFPGLIPILNS
YLENMEVDVDTRCTILNYLKLIKKRASGELMTVARWMREFIAQHPDYKQDSVITDEMNYS
LIWKCNQIALGQAECPELLGVGFNKKPSGNKTDPL
NT seq
1908 nt
NT seq
+upstream
nt +downstream
nt
atggggctgctgtcgcagggctcgccgctgagctgggaggagacgcggcggtacgcggag
cacgtgcggaagcacggcatcctccagttcctccacatctaccgcgcgctgcgcgaccgc
cacaaggacgtcctcaagtggggcgacgaggtggagtatatgttagtaaaatttgaccat
gagaataagaaagtacgcttagtgctgagtggtgaagaagttcttcagacgctgcaagac
aagggggagaagataaaccccaaccacccaacactctggcgaccagaatacggaagctat
atgattgaaggcacacctgggcagccatacgggggaaccatgtctgaattcaacactgtt
caagacaacatgaggaaaaggaggcaagaggccgcttctgtgctgaaagaaaatgaggct
atttgcactgtgacatcttttccaaggttagggtgtcctggatttacgctgccagaatat
aagccaacaccagtagaaggaggagcttcaaaatccctcttctttccagatgaagccatc
aataaacatcctagatttagtacgctgaccagaaacattcggcaccgaagaggagagaag
gttgtcataaatgtaccgatctttaaagataagaatacaccatcaccgtttatagaaaca
tttcctaatgatgatggagaagcagcaaaagcagcgaaaccagactttatatatatggac
gctatggggtttggaatgggcaactgctgtcttcaggtaacattccaggcttgcagcatt
tctgaagcaagatatctctatgatcaactagctacaatctgtcccattgtgatggccttg
agtgctgcatctccattctacagaggctatgtgtccgatattgattgtcgctggggagtc
atatctgcatctgtggatgatcgaacgcgagaagagagggggctggagccactgaagaac
aaccattatagaatcagtaaatccagatatgattccatagacagttatctatctgaatgt
ggtgagaaatacaatgacattgatttgacaatagacaaagatatctacgagcacctaata
aaggaaggtattgaccaccttttggcacagcatattgcacacttgtttattcgagaccca
ttgactttgtttgaggagaaaatacatctagatgatgcaaatgaatccgaccattttgag
aacattcagtctacaaactggcagacaatgagatttaaaccaccccctccaaattcagat
ataggatggagagtggaattcaggcctatggaggtccagttaacagactttgaaaactct
gcgtatgttgtgtttgtggtactgctaactcgagtgattctgtcatacaaactggatttt
ctcattcctttgtctaaggtggatgaaaatatgaagatggcccagaaaagagatgctgtt
cggcagggaatgttttacttcagaaaggatatttgcaaaggtggaaatgtcgtggatgga
tgtggctctgcacaaaatgggacgggcacagacacggaagagtacaccttaatgagcatt
gatacaattataaacgggaaggaaggagtcttccctggtttgatcccaattttgaattct
taccttgaaaacatggaggtggatgtggacacaagatgcaccatcctaaactacctgaag
ttaataaaaaagagagcatctggagaactaatgacagtcgcccggtggatgagggaattc
atcgcacagcacccagactacaagcaggatagtgtgataacagatgaaatgaattacagc
cttatttggaaatgcaaccaaatcgcgctaggccaagcagaatgtccagaactgttgggg
gtaggatttaacaagaaaccaagtggaaacaaaactgaccctttgtaa
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