Listeria monocytogenes CFSAN006122: Y193_01725
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Entry
Y193_01725 CDS
T03478
Symbol
gshAB
Name
(GenBank) bifunctional glutamate--cysteine ligase GshA/glutathione synthetase GshB
KO
K01919
glutamate--cysteine ligase [EC:
6.3.2.2
]
Organism
lmv
Listeria monocytogenes CFSAN006122
Pathway
lmv00270
Cysteine and methionine metabolism
lmv00480
Glutathione metabolism
lmv01100
Metabolic pathways
lmv01240
Biosynthesis of cofactors
Brite
KEGG Orthology (KO) [BR:
lmv00001
]
09100 Metabolism
09105 Amino acid metabolism
00270 Cysteine and methionine metabolism
Y193_01725 (gshAB)
09106 Metabolism of other amino acids
00480 Glutathione metabolism
Y193_01725 (gshAB)
Enzymes [BR:
lmv01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.2 glutamate---cysteine ligase
Y193_01725 (gshAB)
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Gene cluster
GFIT
Motif
Pfam:
Glu_cys_ligase
ATP-grasp_6
RimK
Dala_Dala_lig_C
GARS_A
ATP-grasp_3
ATPgrasp_ST
ATP-grasp
Motif
Other DBs
NCBI-ProteinID:
AHY97088
UniProt:
A0A3A2NA43
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Position
2817430..2819760
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AA seq
776 aa
AA seq
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MIKLDMTMLDSFKEDPKLRKLLFSGHFGLEKENIRVTSDGKLALTPHPAIFGPKEDNPYI
KTDFSESQIEMITPVTDSIDSVYEWLENLHNIVSLRSENELLWPSSNPPILPAEEDIPIA
EYKTPDSPDRKYREHLAKGYGKKIQLLSGIHYNFSFPEALIDGLYDKISLPEESKQDFKN
RLYLKVAKYFMKNRWLLIYLTGASPVYLADFSKTKHDESLPDGSSALRDGISLRNSNAGY
KNKEALYVDYNSFDAYISSISNYIEAGKIESMREFYNPIRLKNAHTDQTVESLAEHGVEY
LEIRSIDLNPLESNGISKDELAFIHLFLIKGLLSEDRELCSNNQQLADENENNIALNGLA
QPALKNCDNEEISVVEAGLLELNKMSDFIQSLRPEDTKLQAIIEKQKERLLHPEKTIAAQ
VKQQVTKEGYVDFHLNQAKTYMEETEALAYKLIGAEDMELSTQIIWKDAIARGIKVDVLD
RAENFLRFQKGDHVEYVKQASKTSKDNYVSVLMMENKVVTKLVLAEHDIRVPFGDSFSDQ
ALALEAFSLFEDKQIVVKPKSTNYGWGISIFKNKFTLEDYQEALNIAFSYDSSVIIEEFI
PGDEFRFLVINDKVEAVLKRVPANVTGDGIHTVRELVEEKNTDPLRGTDHLKPLEKIRTG
PEETLMLSMQNLSWDSIPKAEEIIYLRENSNVSTGGDSIDYTEEMDDYFKEIAIRATQVL
DAKICGVDIIVPRETIDRDKHAIIELNFNPAMHMHCFPYQGEKKKIGDKILDFLFE
NT seq
2331 nt
NT seq
+upstream
nt +downstream
nt
atgataaaacttgatatgaccatgcttgattcttttaaagaagaccctaagctccggaag
cttttattttctggacattttggtttagaaaaagaaaatattcgcgtaacttctgatgga
aaattggctcttacgccacatcccgctatttttggtccaaaagaggataacccatatatt
aaaaccgatttttcggaaagtcagattgaaatgattaccccggtaacggactcgattgac
tctgtatatgaatggcttgaaaatcttcataatatcgtttcgttgcgctcagaaaacgaa
ctactttggccgtctagcaatccacccattttaccagccgaagaagatattccaattgct
gaatataaaacgcctgatagcccggacagaaaataccgcgaacatttagcaaaaggctac
ggtaaaaaaatccaattattatctggcattcattataacttctcattcccagaagcttta
attgacgggctttatgacaaaattagtcttccagaagaatcaaagcaagattttaaaaat
cggctatatttaaaagtcgcaaaatactttatgaaaaatcgctggttgcttatttattta
actggcgcaagtccggtttaccttgctgatttctcgaaaacgaagcacgatgaatccctt
ccggacggtagtagcgcgcttcgtgatggaatttctcttcgaaatagtaatgctggttat
aaaaacaaagaagctctttacgttgattacaattctttcgacgcttatatttctagcatc
tctaactatatcgaagcagggaaaatcgagagtatgcgtgaattttacaacccgattcgt
ttgaaaaatgcgcataccgaccaaacagtcgaaagtttagcggagcacggcgtggaatat
ttagaaattcgctctattgatctgaatccattagagtcgaatggtatttctaaagacgag
cttgcttttattcacctatttttaattaaaggtttgctttcagaagatcgcgaattatgc
tccaacaaccaacaattagccgatgaaaatgaaaataatattgcgctaaatggtctcgcg
caacctgcccttaaaaattgtgataatgaagaaatatctgtcgtagaggccgggctttta
gagcttaataagatgagcgatttcatccaaagcttgcgaccagaagacaccaaactccaa
gcaatcatcgaaaaacaaaaagaacgtctgctacaccctgaaaaaacgattgctgcacaa
gtgaaacaacaagtaacaaaagaaggctacgttgacttccatttaaaccaagccaaaact
tacatggaagaaaccgaagctttagcctacaaattgattggcgcagaagacatggagctt
tccacccaaatcatttggaaagacgccatcgcgcgcggcatcaaagtcgatgtattagac
cgggccgaaaacttccttcgcttccaaaaaggcgaccatgtggagtatgtaaaacaagcg
agcaaaacatccaaagacaactacgtttccgttttaatgatggaaaataaagtagttact
aaacttgtacttgcagaacatgatattcgcgttccatttggcgacagttttagcgaccaa
gcccttgcactagaagctttctccctatttgaggataaacaaattgtcgttaaaccaaaa
tccaccaactacgggtggggtatcagtatttttaaaaataaattcacgctggaagattac
caagaagctttaaatatcgcatttagctatgatagctccgttattatcgaagagttcatt
cctggcgacgaattccgcttcttagttattaacgacaaagttgaagctgtactaaaacgt
gtccccgctaacgtaaccggcgacggaatccatacagtgcgcgagctggttgaagaaaag
aacactgatcctttgcgcggaacagaccatttgaaaccacttgaaaaaatccgtactggt
ccagaagaaacgctcatgctctctatgcaaaacctttcttgggacagcatacctaaagca
gaagagattatctaccttcgcgaaaactccaacgtcagcacaggtggagacagcattgac
tatactgaagagatggacgattacttcaaagagatagctattcgtgcgacacaagtactt
gacgccaaaatttgcggcgtagacataattgttccacgtgaaacaatcgaccgtgataag
catgctatcatcgagcttaatttcaatcccgcgatgcacatgcactgcttcccttatcaa
ggggagaagaaaaaaattggtgataagattttagatttcttatttgaataa
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