Loa loa (eye worm): LOAG_16448 Help Entry LOAG_16448        CDS       T02664                                  Name (RefSeq) WWE domain-containing protein   KO K10592   E3 ubiquitin-protein ligase HUWE1 [EC:2.3.2.26] Organism loa  Loa loa (eye worm) Pathway loa04120   Ubiquitin mediated proteolysis loa04137   Mitophagy - animal Brite KEGG Orthology (KO) [BR:loa00001]  09120 Genetic Information Processing   09123 Folding, sorting and degradation    04120 Ubiquitin mediated proteolysis     LOAG_16448  09140 Cellular Processes   09141 Transport and catabolism    04137 Mitophagy - animal     LOAG_16448  09180 Brite Hierarchies   09182 Protein families: genetic information processing    04121 Ubiquitin system [BR:loa04121]     LOAG_16448 Enzymes [BR:loa01000]  2. Transferases   2.3  Acyltransferases    2.3.2  Aminoacyltransferases     2.3.2.26  HECT-type E3 ubiquitin transferase      LOAG_16448 Ubiquitin system [BR:loa04121]  Ubiquitin ligases (E3)   HECT type E3    LOAG_16448 BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  HECT DUF913 UBM DUF908 WWE UBA WWE_5 Arm_2 Motif Other DBs NCBI-GeneID:  9943563 NCBI-ProteinID:  XP_020307475 UniProt:  A0A1S0UMG1 LinkDB All DBs AA seq 3651 aa AA seqDB search MKIDSKTLRPCSAEIFPRCMQLIEHIKSASDRRTFLERLTEVHEWQPQFGKSEMARWSDV LNMCDDVLKDAVTCSSSPGAPMAIDEDQTLLADVTSVLSFTAMLFENTFTRSVYSSTDRL LNLLDSGNVEVVVETLRLLLVISKRSRFLSQHLNEVQQKKLTVRLSAIAQCWNGKLRSIK MDECCTANVQPTTLLPIGFQTDTNNLVRSIHLDKSFAAELEHLLFGKKIEEDERASFIAR LRLVRSFNTSRGRRLSIIARLLSLSILVYTRSLIEEWAMTTMLYDGLIEEITRLLLINNT SESIIDAVKTEALRTLTSIVSLGRPAKLNVVVESLGVNSYHGFLARMTRQCVDDLRCGRI GNGYTTVPFCTALFSLLYHLAGFENGGEALVSCALTETLLGVVSCETLPLELITFVTRAV RVIDIMTSLDANGFTSCNGMSIIVHRLIFDVNICMKHLAELSITGPTAEQCHQQRAALIK SLLNFIKRAVQDAQFADSTRHIMDGALPAALVNILTNCGFFGASLFHNAVCLITNFIYQE PSLLTSLQEKGVTSAILRAIFRQELPTSRDVIAALPNTFTALCLNDRGLKAFMNENPFDH FCDIFVSTKYIYAMKCRRNEMNEVALNLGTSFDAFLRHHPTLRESFLNSFAKMLNKLLDV ASTDSPRCVMSLASCRSAQTTSASSSNLAVSSASPSQEDETIMAGNVSSDDDDDDPTSAV ANMEEMHTTENESPQLDLGLSLSIVCDGNPLVPLGEYLLNIGKFLETLLTHNASPEQADV FIQSGAADKLLSLLFVRQIPLELSQSLFPQLVTNIMRFLFQHTRSNDVMDMVANRLNKFC LDMLSSCSTNDDSSKLSLLAMSSSDASLANICAISVFCSVLGSLSKAALGSNTATKTAVL RFWTNEGCRLLASCNQAQRIVVWECAVLQIYNATNKCAASTQTDDVQTDEQIEDANVTLK QGSVGTDSVPQRIGRPKYLLDDYWLRSKSGTSALSRCNRHCTELMTMLVKISIGGMTRTR RIQENEGGTPCENAVQLALQIMKGFQQALEWKPHDETDPAIMLPYLAVWINNLSNILFDE RKSPYHLMLSAFYRTGTHDTFFNIISNYFAPDQDQNYCEVGQLLQAWLSLAERLVNAHAF RHSRYKMSERFAEAKRFPTEKYLAKCQQDAFRQANVVFGVLSALPLSEAVSFNICDMIVS IYREIVKGIVPLTEKQKQAVVTTSEDRKKMEAELDGASIGLLVDMGFDRDAAVDALLEYS TVPEAAEYLIATDGLGRLRQSSTDERIDADDIDAEEGSGGQNGDLNVEFEDVLLKEPISL NEVPPLDTRLVLSSLCKDVIPILLNLMEQGTELVFSTSEIMLAILNEVDDDWRKNVLIGE YLVQDILLMVDELRCDETDEKAVISLSTRLHFVCLLWPGIATTYMDIFTKYCLHSVLISV LDMVVIHCLRRPAFIRLIAPICLWLDLYDKMLKLLDSKDKVEKAVESYAWKYWDTDERGG VFTWINYPPAASHALTNAFLSGRRNCNVSVGGRQYTVDFPSMSHRNVESHIERPITISGR LKDGIILSEILAESNEHKEWNEVVRDGLVPAIIGLLGLSNIDATSIHAIFILAARITRDF KIAKEFLQQGGVQTVINVSGSAVPSSAVLAALIIRHCLDDEIAVRQIFEKTVRTIAAGGY TINPPFTRWNHIRTPRTTRDWLHAIRALSPLCARHPQIFADTMERVTRKQKDQITVLPMT PVDPSCKQWAACSPIKQVLTHLLNHTLDFSWEDSNRVINRASLVRLIAELAKSYSIVATL VAESHDPNGQLFMVSLLSKCVVPSGSSATDGNLCMAVKTFVAAIASCSHSPKAQEALISS IISCLHIVFSEADSKATCTKLRLLSDMFLLARDACPAGPQDMRNSTNSNAILRLIIKKRV CIELSRVPWYLNLSAKEGIETLNYILRVLEELTRAINSNHAAQNSMENASEALTTTQNAS ASVTLVATSENDASATVTAREGEHSQDNQHVEDGNSTADEHRFETHEFQVTVERNRPDDD YCADDDEDRGHARHPDAVEDSSESEEDEDDADDDDDDEGAGLNEMDVDDESDDEHDDVME EEGRVSVEEEDDFGMVEMEPGALSRFALVDSVDDSGPVDRFEDGDSEENFVNTNIFVENL DDIDALTSGAFTGARLFVNTSLEAAHADRSSATVSSVHPLLQRSSQTSGSDSIIGQRPTS YRLLVGQRRGAGNVNPTGLHRQNAVRRWTTFGTQSEFIERLFDGSAAANGTHLFDIAPSR QRFLNVVMQDHGLDNTTTVTSEERRQTSVPLPLERFSDAARMIDGHAHLYLWVMVASHVT GVMDAIEKDENVKKAEEEIMKTQKDFTEDSSKRTLDDAASNESTSTTRLFIDEEDNGGVG NPNGIADTQPEHSSESIDITVQMHNVPEPMDQSGTLYYDASEIFENQIQQISEQEQGQSN VASNGSSNILTGASMHALPITVDQTEGQGNMEQLSTLEATAGTPHANQDDFREILGDIEI PDGVDPAFLAALPEDIRMEVIRDHMRQQRSQRLIQTSANLEAAGQANGEVPAVEPLDQEF LNALPPDLQEEILAQHERTVRLAQERAESNSAPPADTPVAADDAAALIESLPPTLRAQVL ADADDTVLQVLPQNVAAEARRLRASYEAQQVMRFARMLAPAQRFRPANGRSVPGTSGNST PVGALAGVTTLASKNATQLLDRDAIVTLLLLFLIDPVRLNTQRLQKLIKSLCAQNVTCDF IIWCLIALLDKVDEDAVQYEDFAGTVSGWLDQICIHSGIGQHEQAVKFFKSTHIVALHPA ILATVCRLVLDTLISLAKSYPGHFLPAKLRESGSPSNAGLHTPPFSQFWAIVHSLSKADM SSRSTHRHGSSLETALGPGGVNASMAALSLEDSAVGVLMEHIRRPVILSSSILQDKLLRL ICTIVQTLPDETVTKMSIDSIAERPPLTQQLEHIVLALTEGECSEEGLADGRTLLLELIR ALTPSTKAFIMSLLINAAERLGARLLQHIERLEEELKELRNEGNRSSSLEQQPSGSKVAV NRYDESVIVISGILNSRAVMNASGCYELQLPAMRALTDKNGIQNIFLRTLQTIIKIREVL QLHARCTEVDVSIDTAGEQDDEHVPGEDDENAIEENERKRLAEKEESMSVLLNTLEPLWE LVSRCLKRLTNADAHAALALQPSAEAFFLVYGSELSSIDPSKLHEHPDAQKLLHFAEKHR NMLNQVLRQSGGSLTDGPFAVLTQMPKLLDFDVKRIYFRKQMQKIDERVRGEDVAVRIRR SHLFSDSFRELFRLRGPEWKARFYIIFEGEEGQDAGGLLREWFSIITREIFNPNYALFIT SPGDRVTYMINKTSYINPEHLEYFKFVGRIIAKAIYENKLLECYFTRAFYKHILSVPVRA QDLESEDPSFYKSLEFLLNNPIEDLGTELTFSLEVEEFGVRKMRMLKENGSSIPVTDENK EEYVKLVCQMKMTGSINQQLKAFLEGFYEIIPKHLISIFNEQELELLISGLPNVDIDDLY ANTEYKTYTKSSSQIQWFWKALRSFEQEDRAKFLQFVTGTSKVPLQGFAALEGMNGTQKF SIHLDSRSSDRLPTAHTCFNQLDLPQYETYDKLRDMLLLAVRECTEGFGFA NT seq 10956 nt NT seq  +upstreamnt  +downstreamnt atgaaaatcgattctaaaacgttacggccgtgtagtgcagaaatttttccccgatgtatg caacttattgaacatatcaaatcagcttcggatcggcgaacatttctggagcggttaact gaagttcatgaatggcagccacagtttgggaagtccgaaatggcgaggtggtcagacgtt ttgaatatgtgcgatgatgtattgaaagatgccgtaacgtgtagttcgtcaccgggtgca ccgatggctatcgacgaagatcagactttattagcagacgtcacatctgttctttctttt accgccatgcttttcgagaatactttcacccgttcagtctacagttctaccgaccgactg ttaaacttgctagattctggtaatgtggaggttgttgtggagacgttgagattattattg gttatcagtaagcgctctagatttctttcacaacacctcaatgaagtccaacaaaaaaaa ctcactgtccgactttctgctattgctcagtgttggaatggtaaactcagaagtattaag atggatgaatgttgtactgcgaatgttcagcctaccactttgttaccaatcggatttcag acggatacgaataatcttgttcgttctatacatttagataaaagttttgcggccgagctg gaacacttgttatttggtaaaaaaattgaagaagatgaacgtgcatctttcatagctcgc ttacgtctggtgcggtcatttaacacttctcgtggtcgacgtctaagtattattgcgcgt cttctttcgttgtctatattagtttacactcgtagtttgatagaagaatgggcaatgact acaatgctttatgatggacttattgaagaaataactcgtttattactgattaataatact tcggaatcaattattgatgctgttaaaacggaagcacttcgtacactaaccagtattgtt tcacttggaagacctgcaaaattgaacgtagtagtagaatccctcggagtgaattcatat cacggtttcttggctcgaatgacccgccagtgtgtcgacgacttgcggtgcggaagaatt ggaaatgggtatacaaccgtaccattctgtaccgccttgttttctttgctttatcatctt gctggctttgaaaacggcggtgaagcattagtttcgtgcgctttaacggagacattactg ggtgtggtatcatgcgaaacgctgcctttagaactgattacctttgtgacacgcgctgtg cgcgttatcgatatcatgacttcgttagatgctaatggttttacatcttgcaatgggatg agcattattgttcaccgcttaatttttgatgtcaatatatgtatgaaacatttggcagaa ctgagtatcactggacctacagcagaacagtgtcatcagcagcgtgctgcattgattaaa tcattactaaatttcatcaaaagagctgttcaggatgcacagtttgctgatagtactcga catattatggacggtgccttaccggctgctttagtgaacatcttgacaaactgcggattt tttggagcttcactgttccataatgctgtttgcttgattacaaatttcatctaccaggaa ccttcgttacttacgtccttgcaagagaaaggtgttacgagtgctattctaagggcaata ttccgtcaagaattgcccacttctcgagatgtcattgctgcattaccaaacacatttact gctctttgtttaaacgatcgtggactgaaagcttttatgaatgaaaatcctttcgatcac ttctgtgacattttcgtgtcaacaaaatacatatacgccatgaaatgtcgtcgcaacgaa atgaatgaggtggccttaaatctgggcacgtcgttcgatgcctttttgcgccatcacccg accttgcgagaaagttttctcaattcgtttgctaagatgttgaacaaattgctggatgtt gcatctacggattctccacgctgtgtcatgtctcttgcatcatgtcgcagtgctcaaaca acctcagcaagttcttcgaatttagccgtttcatcggcttctcctagccaagaagacgag actatcatggcaggcaatgtttcttcggatgatgacgatgatgatccaacttcagctgtt gcaaatatggaagaaatgcatacaaccgaaaatgaatcacctcagctcgatcttggtctg tcgttgtcgattgtgtgcgatggaaatccacttgttcctcttggcgagtatctgttgaat atcggaaaatttctggaaacgcttttaactcataatgcatcacctgagcaggctgatgtt tttatacagtctggcgctgctgataaattgctttctttactttttgttcggcagattcct ttagaattatcgcaatcactgtttccgcaattggtcacgaacataatgcggtttctcttt caacatacaaggagtaatgatgtgatggacatggttgcgaatcggctgaacaaattttgt ctggatatgttaagttcatgtagcacgaatgatgattcatcgaagttatcattgcttgcg atgagctcgtcagacgcttcgttggcaaacatttgtgcgatttcagttttctgttctgtt ctcggcagcttatcaaaagctgctctaggaagtaacacagcaactaaaacagcagttctc agattttggacaaatgaaggttgtagacttctcgcttcctgtaatcaggctcagagaata gttgtttgggaatgtgcagttttacaaatatataatgcaacgaataaatgcgccgcttct acacaaacagatgatgttcaaacagatgaacaaatagaagacgctaatgtaactctgaag cagggttcagttgggacggatagtgtaccacagcgcattggtcgaccgaaatatctgctt gatgactactggcttcgttcaaaatcaggaaccagtgcactgagccgctgcaatcggcat tgtacggagttgatgacaatgcttgtcaagatatctatcggtgggatgaccagaacgaga agaattcaggaaaatgagggtggcactccatgcgaaaatgctgtgcagctagcacttcaa ataatgaaaggtttccaacaagctctggagtggaaaccgcacgatgaaactgacccagct ataatgttgccatatttggcagtctggatcaacaatctcagcaacattctatttgatgag cggaagagtccttatcatttaatgctttctgctttttatcgtaccggcactcatgataca tttttcaacattatctcgaattacttcgcaccagatcaggatcaaaattattgtgaagtg ggacagttgttacaagcctggctatctctagcggaacgactggttaatgcgcacgcattc cgccattcacgctataaaatgtcggaaagatttgcggaagccaagcgttttccaaccgag aaatatctcgcaaaatgccaacaggatgcttttcgacaggccaatgttgtatttggagtg ttatcggcattacccttaagcgaagccgttagttttaacatctgtgacatgattgtttcg atatatcgtgaaatagtcaaaggaatagtgcctttaactgaaaaacaaaagcaagctgtg gtcacaacgtctgaagatcgcaagaaaatggaagcagaacttgatggggcgagtattggt ctcttagttgacatgggattcgatcgtgacgctgctgttgatgcactgctggagtattcg accgttccagaggctgccgaatatctgatcgcaactgacggcttaggcagacttcgccag tcgtcaactgatgaaagaatagatgctgatgatatcgatgcggaagaaggaagtggtggc caaaatggtgatttgaatgtagaatttgaagatgtccttttgaaagagccaatttccttg aacgaagtacctcctctcgacacccgtctagtattatctagcctatgcaaagatgttatt ccaattcttttgaatttgatggaacagggtacagagttggtgttcagtacatcggaaatt atgctggcaatcttaaatgaagtagacgatgattggagaaaaaatgtgcttattggtgaa tatttggtgcaagatattctattgatggtggacgaattacgctgtgacgagactgacgag aaggcagttatatcgctttcaactcgtttgcacttcgtatgtttgctatggcctggtatt gctactacttatatggatatctttacaaagtattgtcttcatagtgtgttgatttctgtg cttgacatggttgtcatacactgtttaagaagacctgcatttattagacttatcgcaccg atatgtttgtggcttgatctgtatgataaaatgttgaagttattggatagcaaggataaa gttgaaaaggctgttgaatcatatgcatggaaatactgggataccgatgaaagaggtggt gtatttacttggattaattatcctcctgcggcctcgcatgcactcacaaacgcatttctt tctggtcgaagaaactgtaacgtaagcgtaggaggccgtcaatacactgttgattttccg tcaatgagccatcgtaacgttgagtctcacattgaacgaccgattacaatttctggccgc ctgaaggatgggattatattatccgaaatacttgctgagagtaacgagcataaagaatgg aatgaggtagtacgtgatggacttgtaccagctatcattggccttcttggcttatcaaat atcgatgcaacctcgatccatgcaatttttattttggctgcacgtattacgagagatttc aaaattgctaaggaatttttacagcaaggaggtgtgcaaacagtgataaatgtatcgggt tccgcagtaccgtcatcagctgttcttgcggcccttatcattcgtcactgtcttgatgat gaaattgcggtaagacagattttcgaaaaaacagtgcgtacaattgccgctggtggttat actatcaatcccccttttacaagatggaatcatattaggacaccgcgaacaactcgtgac tggctacatgctatacgtgccctttctccgctatgtgcacgccatccacaaattttcgct gatactatggaacgcgttacacggaaacagaaggatcagataaccgttttaccgatgact ccagttgatccttcttgtaagcagtgggctgcgtgctcacctattaaacaggtattgacg catttactgaatcacacgttggacttttcatgggaagactcgaatagagtgattaatcgt gcatcacttgtgcgactgattgctgagttggcgaagagttacagtatcgtagcaacatta gttgctgaatcgcatgatcctaatgggcaactttttatggtttcgctccttagtaaatgt gttgtcccaagcggttcttctgctactgatggtaatctttgtatggctgtgaagactttt gtagctgcaatcgcttcatgcagtcattcaccaaaagctcaggaagcgttgatttccagt attatttcttgtcttcatattgttttctctgaagctgattcaaaagcaacatgtaccaag ctgagattattatcggatatgtttctgttggcacgtgatgcatgtcctgcaggaccgcaa gatatgcgcaacagcacaaattcaaatgcgattttacgcttgattataaagaaacgtgtt tgtatcgagctgagtagagtgccatggtatttgaatttatcagcgaaggagggtatcgag acattgaactacattctgcgagttttggaagagttgacgcgtgcaatcaatagtaaccat gctgcacagaattcaatggaaaatgcatcagaagcgctaacaacgactcagaacgcttca gcatctgtaacactagttgcaacatcagaaaacgatgcatcagccacggtaacagcgaga gagggtgaacattcccaggataatcaacatgtcgaagacggcaatagtactgccgatgaa catcgttttgagacccatgagttccaggtaacggttgaacgaaatagacctgatgatgat tactgtgcggacgatgatgaggatcgtggtcacgctagacatccggatgctgttgaagat tcaagtgaaagtgaagaggacgaggatgatgcagatgacgacgatgatgatgaaggtgct ggtcttaatgaaatggatgtggatgatgaatcggatgatgaacatgatgatgtaatggaa gaagaaggacgtgtgagcgttgaagaagaagacgattttggaatggtagaaatggagcca ggagcattaagtcgttttgccttagttgatagtgtggatgattctggacccgtagatcga tttgaagacggcgattccgaggaaaattttgtcaacacaaatatatttgttgaaaatttg gatgatattgatgctcttacaagcggtgcttttacgggtgcccgcctttttgtaaatact agtttggaagctgcgcatgctgatcgatcgtcggctacagttagttcggtgcatccctta ttgcagagatcatcacagaccagtggcagtgatagcattataggtcaaagacctacgagt tatcgccttctggttggtcagcgtcgtggagctggaaatgtaaatccaacaggcttacat cgacaaaatgcagtacgacgttggacgacatttggtacacaaagtgaatttatcgaacga ctatttgatggctctgcagcagctaatggcactcatcttttcgatatcgctccgtcacgt caacgcttcttgaatgtcgttatgcaagaccatggattggataatacaactacagttact agtgaagaacgacggcaaacatctgttccacttccacttgaacgattttcagatgctgca aggatgattgatggtcatgctcatttgtacttgtgggtgatggttgcatctcatgtcacc ggtgttatggatgctattgagaaggacgaaaatgtgaagaaagcagaagaagaaataatg aaaacgcagaaggattttacggaagattcttcgaagagaacgctggatgatgctgcatca aatgaaagtaccagtacaacacgattatttattgatgaggaagacaatggaggtgttgga aaccctaatggtattgctgatacacagccagaacattcatcagaatctattgatataaca gttcaaatgcataacgtcccagaacccatggaccagtccggaactttgtattacgatgct tcggagatttttgaaaatcaaatccagcaaatttctgaacaagagcaggggcaaagcaat gttgcttcaaatggaagcagtaatattttaacaggcgcatcaatgcatgcactaccaatt actgtagatcaaactgaaggacaaggaaatatggagcaactaagcactctcgaagctacg gcgggaacgccgcatgctaatcaagatgatttcagggaaatattaggagatattgaaatt cccgatggtgtagaccctgcgtttttggcggccttaccggaagacatacgtatggaagtg attcgcgatcatatgaggcagcaacgttcacagcgtttgatacaaacttctgcaaaccta gaggcagccgggcaggcaaatggtgaagtgcctgcagttgaaccacttgatcaagaattc ctaaacgcactcccacctgatctgcaggaagaaatcttggcgcagcatgagaggactgtg cgattagctcaggaaagagcggaaagtaatagtgcaccgccggcagacactccggttgct gctgatgatgcagctgcattgattgaatcacttccgccaactctgcgagcacaagtgctc gctgatgcggatgacacagtcttacaagttctaccccagaatgttgcagccgaagcacgg cgtttgcgagcatcttatgaggcacaacaagttatgcgttttgcccgtatgttagcacca gctcaacgctttcgccctgcaaatggtcgatcggtgcctggaacaagcggaaacagtact cctgtaggtgcacttgctggagttactacacttgcttcaaagaatgctacacagttattg gatcgagatgccattgtcacattattacttcttttcctcatcgatccagtccgtcttaat actcagcgcttacagaagctcatcaaaagtctttgcgcacaaaatgtaacatgtgatttt ataatctggtgcttaattgctctacttgacaaagtagacgaagatgctgttcagtatgaa gactttgcgggcactgtatccggttggttagatcagatatgcatacacagcggtattgga caacatgaacaagcggtcaaattcttcaaaagtactcatatagttgctttacatccggca atcctagcaacagtttgtcgtcttgtactggatacactaatcagtcttgcaaaaagttat ccgggtcattttcttcctgcgaaactacgtgagtcaggttctccttctaatgctggatta catacgccaccattctcacagttttgggctatcgttcatagcctgtcgaaagctgatatg tcatctcgttctacgcatcgtcacggttcatcattagaaacagctttgggaccaggtggc gttaatgcaagtatggctgctttatctcttgaagatagtgctgttggcgtacttatggag cacattaggcgtccagttattctctcatcttcgatattgcaggataagttgcttcgcctt atatgtacgatcgtccagactttgccggatgaaaccgtcacgaaaatgtcgattgattcg atagcagaaagacctccacttactcaacaactcgagcacattgttttggccttgacggaa ggtgaatgttcggaagaaggattagcagatggacgaactttactgctagaattgatccgt gctctcactccatccacgaaagcttttataatgtctcttctcataaatgctgctgaacgc ctaggagctcgacttctgcaacacattgagagacttgaagaagagctgaaagagctgcgc aatgaaggaaaccgttcatcatcgcttgagcagcaaccatcaggctcgaaagttgcagtt aatcgttatgatgaatcagtcattgtgatcagtggaatattgaattcacgggcagtcatg aatgcatctggttgttatgaactacagttaccagcaatgagagcacttactgacaaaaat ggcatccaaaatatatttctgagaacgctgcaaacaattatcaaaataagagaagtactg caattacatgcaaggtgtactgaggttgacgtgagtattgacaccgcaggtgagcaggat gatgaacatgtacctggagaggatgacgaaaatgcaatcgaagaaaatgaaaggaaaaga cttgcagagaaagaagaaagcatgagcgtattattgaatacgttagaaccgttatgggaa cttgtatcaagatgtctgaaacgtcttacaaatgcagatgcacatgcagctttagctctt cagccaagcgccgaagctttttttctggtatatggatcggaattgtcttctattgatcca agcaaactacacgagcacccagatgctcaaaaacttcttcatttcgcagaaaaacaccgg aatatgttgaatcaggttttgaggcagagtggtggtagtttaacggatgggccattcgca gtactaactcagatgccgaaattgttggactttgatgtcaaacgtatctacttccggaaa cagatgcagaaaatcgatgaacgtgttagaggcgaagacgttgcggtgcggattcgtcgc agtcacttattcagcgatagttttcgggaattattcagactacgtggtccggaatggaaa gcgagattttacatcatcttcgaaggcgaagaaggacaagatgctggtggattattgcgt gaatggttttcaatcatcacacgggaaattttcaatccgaactatgcactctttataact tctccaggagatcgtgtaacatatatgatcaataagacttcatatattaatccagaacat ttggaatatttcaagtttgttggaagaataatagcgaaggcaatatatgagaacaaatta ttggaatgttattttactcgagcattttataaacacattttaagtgttcctgtacgagca caagacttagaatcggaggatccgagtttctacaagtcattggaattcttgctcaataat ccaatcgaagatcttggtactgaacttacatttagtttggaggttgaagaatttggagtt aggaaaatgcgcatgctgaaagaaaatggatcatctattccagttactgatgaaaataag gaagaatatgtgaagctggtttgtcaaatgaaaatgactggctccattaatcagcagttg aaagcgtttttggagggcttttacgaaataattccgaagcatttaatatcaattttcaat gagcaagaattggagttgttgataagtgggcttccaaatgttgatatcgatgatctctat gccaatacagagtacaagacttacactaaatcctcgtctcagatacaatggttctggaaa gcattgcgttcatttgaacaggaagatcgtgcaaagtttctgcagttcgttactggtaca agcaaagtacccctgcaaggttttgctgctcttgagggtatgaacggtacacagaaattt tccattcatttggattcgcgatcttcagatcggctaccaacagcacatacatgcttcaat cagttggatcttccgcaatatgaaacatatgataaacttcgggatatgttattgctagcc gtacgtgaatgcaccgaaggatttggttttgcttaa

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