KEGG   Lacticaseibacillus parahuelsenbergensis: LACPH_001363
Entry
LACPH_001363      CDS       T10275                                 
Symbol
nrdE
Name
(GenBank) class 1b ribonucleoside-diphosphate reductase subunit alpha
  KO
K00525  ribonucleoside-diphosphate reductase alpha chain [EC:1.17.4.1]
Organism
lpah  Lacticaseibacillus parahuelsenbergensis
Pathway
lpah00230  Purine metabolism
lpah00240  Pyrimidine metabolism
lpah01100  Metabolic pathways
lpah01232  Nucleotide metabolism
Module
lpah_M00053  Deoxyribonucleotide biosynthesis, ADP/GDP/CDP/UDP => dATP/dGTP/dCTP/dUTP
lpah_M00938  Pyrimidine deoxyribonucleotide biosynthesis, UDP => dTTP
Brite
KEGG Orthology (KO) [BR:lpah00001]
 09100 Metabolism
  09104 Nucleotide metabolism
   00230 Purine metabolism
    LACPH_001363 (nrdE)
   00240 Pyrimidine metabolism
    LACPH_001363 (nrdE)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   03400 DNA repair and recombination proteins [BR:lpah03400]
    LACPH_001363 (nrdE)
Enzymes [BR:lpah01000]
 1. Oxidoreductases
  1.17  Acting on CH or CH2 groups
   1.17.4  With a disulfide as acceptor
    1.17.4.1  ribonucleoside-diphosphate reductase
     LACPH_001363 (nrdE)
DNA repair and recombination proteins [BR:lpah03400]
 Prokaryotic type
  Other factors with a suspected DNA repair function
   Modulation of nucleotide pools
    LACPH_001363 (nrdE)
SSDB
Motif
Pfam: Ribonuc_red_lgC RNR_N Ribonuc_red_lgN RNR-II_ins_dom
Other DBs
NCBI-ProteinID: WLV79315
UniProt: A0ABY9L6Q2
LinkDB
Position
1455085..1457256
AA seq 723 aa
MSLKTISPDEVTYYALNNEINIPVNDQIPLNKDKEALQAFLTENVAPNTMKFSSLQERLK
YLVDHHYYEADFLKKYQPAFLEKLDQFLTAQHFQFKSFMAAYKYYAQYALKTDDGTQYLE
DYKDRVFANALFFADGNEQLAVDLADEMIHQRYQPATPSFLNAGRQRRGELVSCFLLQIT
DDMNSIGRAINSALELSRIGGGVGLTLSNLREAGAPIKGIDGAASGVLPVMKLLEDSFSY
SNQLGQRQGAGVVYLNVFHPDIISFLGAKKENADEKYRVKTLSLGVIVPDKYYELIKDNA
DMYLFSPYSVERAYGKPFSYVDITKEYDNMVANPDIKKYKIKARDLENEISKLQQESGYP
YIINIDTANNASPIDGKIIMSNLCSEIMQVQVPSKLNNKQEYEVLGTDVSCNLGSTNIPN
LMRSRDFGHSVEAMVRALTYVTDHSNIDVVPSVQHGNHMAHSIGLGAMGLHTYFAKNHMY
YGSPESLDFTNIYFLLLNYYTLKASNKIAKERGESFHNFENSKYADGSYFDKYIQQSWAP
KYDKVCDLFKDVHIPTQADWEALKESVMKDGLYHQNRMAVAPNGSISYINDTSASLQPIV
NRIEDRQEKKIGTIYYPAPGLSNDTMPYYQSAYDIDMRKVIDVYAAAQQHVDQGMAMTLF
MRSTIPAGLYPWKDGRTDKMTTRDLNILRNYAHHKGLKSIYYIRTYTDDQEEIGSNACES
CSI
NT seq 2172 nt   +upstreamnt  +downstreamnt
atgtcattaaaaacaatcagtccggacgaggttacttattacgcccttaacaacgagatc
aatattcccgttaacgaccaaattccgctcaataaggacaaggaagccttacaagccttt
ttgactgaaaatgtggcgccaaatacgatgaagttttcgtcgctacaagagcgcttgaag
tatttggttgaccatcactattatgaagccgactttttaaaaaagtatcagccggccttc
ctggaaaagctggatcaatttctgacggcccagcattttcagtttaagtcctttatggcg
gcctataagtattacgctcagtatgcgttaaagacggacgacggcactcaatatcttgaa
gactacaaagatcgggtgtttgccaatgccctcttctttgcggatggtaatgagcagctg
gcggttgacttagcggatgaaatgatccatcagcggtatcaaccggctaccccttcgttc
ctgaacgctggtcggcaacgccgtggtgaattggtctcctgttttctactgcaaattacc
gacgacatgaattcgattggccgcgcgattaactctgctcttgagttgtcacgaattggt
ggcggggttggcctgacgctgtcgaacctgcgtgaagccggtgcaccaatcaaaggcatt
gacggtgctgcaagtggtgtattgccggtcatgaagttgttggaagattctttttcctat
agcaatcaactgggccaacgtcaaggtgccggtgtggtttatttgaatgtcttccatcct
gatatcatcagtttcctgggtgccaagaaggaaaatgcggatgaaaagtatcgggtaaag
acccttagtctcggcgtcattgtgcctgataagtattacgagcttattaaggacaacgcc
gatatgtatctgttctccccttattcggttgaacgggcttatggcaagccattttcgtat
gtggacattaccaaggaatacgataatatggtggccaatccggacattaagaaatacaag
atcaaggctcgcgatctggaaaatgaaatttccaaattgcagcaggaatctggctatcct
tacatcatcaacatcgacactgccaacaatgcgagtccgatcgatggcaaaatcatcatg
agcaacttgtgctcggaaatcatgcaggtgcaggtaccatccaagcttaacaacaaacag
gaatatgaagtcttagggacagatgtttcctgcaacctaggcagcacgaatattcctaat
ttgatgcgtagtcgcgattttggtcacagcgttgaagccatggttcgggcattgacctat
gtcaccgatcacagcaatatcgacgttgtgccatctgttcagcacggtaatcacatggcg
cacagcatcggccttggtgcgatgggcttgcacacgtactttgctaagaaccatatgtat
tatggttcaccggaaagccttgatttcaccaacatttatttcttgttgctgaattattac
acgttgaaggcatccaacaagattgctaaagaacgtggcgagtccttccataattttgaa
aacagcaaatacgctgatggcagttattttgacaagtatatccaacaatcatgggcacct
aagtacgacaaggtgtgtgatttgttcaaggatgttcacattccgacccaggcggactgg
gaagcgctcaaagagagtgttatgaaggacggcttgtatcatcaaaaccggatggctgtg
gcccctaatggctcgatcagctatattaacgataccagtgcctccttgcagccaattgtt
aaccggatcgaggatcgccaggaaaagaagatcggcaccatttactacccggcgcctggt
ttatcgaatgacaccatgccttactatcaaagtgcctacgacatcgacatgcgtaaagtc
attgatgtttatgccgctgcccaacagcacgttgatcaagggatggcgatgaccttgttc
atgcgtagtaccattcctgctggcctttatccgtggaaagacggccgaaccgacaagatg
acgacgcgtgatttgaatattttgcggaactacgcacatcacaaaggtctgaagtcgatt
tactacatccggacttacaccgatgaccaggaagaaatcggcagcaacgcttgtgaaagt
tgctcaatttga

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