Lysinibacillus pakistanensis: GDS87_09450
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Entry
GDS87_09450 CDS
T06280
Name
(GenBank) UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase
KO
K01929
UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase [EC:
6.3.2.10
]
Organism
lpak
Lysinibacillus pakistanensis
Pathway
lpak00300
Lysine biosynthesis
lpak00550
Peptidoglycan biosynthesis
lpak01100
Metabolic pathways
lpak01502
Vancomycin resistance
Brite
KEGG Orthology (KO) [BR:
lpak00001
]
09100 Metabolism
09105 Amino acid metabolism
00300 Lysine biosynthesis
GDS87_09450
09107 Glycan biosynthesis and metabolism
00550 Peptidoglycan biosynthesis
GDS87_09450
09160 Human Diseases
09175 Drug resistance: antimicrobial
01502 Vancomycin resistance
GDS87_09450
Enzymes [BR:
lpak01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.10 UDP-N-acetylmuramoyl-tripeptide---D-alanyl-D-alanine ligase
GDS87_09450
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Gene cluster
GFIT
Motif
Pfam:
ATPgrasp_YheCD
Mur_ligase_M
Mur_ligase_C
ATPgrasp_ST
GSH-S_ATP
ATP-grasp_3
Birna_VP1_thumb
Motif
Other DBs
NCBI-ProteinID:
QGG51174
LinkDB
All DBs
Position
2027977..2030148
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AA seq
723 aa
AA seq
DB search
MTIIGMLHHRLDPTTVIKSYAYAAVAKAEGAQFFYFTPKSVDFNKRSIRGKVYENGEWLE
KIMPFPDVVYNAGSPEKLSVSKEIIDKLKDEIPFTTHSIGNKWNVMKRLKEAKEFDKYLI
PTEIVKNAELFHKFFSYYKKVVFKPIDGRKGKGIYFITKADSTNFEVRKDSENRVYSKHQ
LDELIKGQLATGTFIMQPYIQSKTKAGQVYDFRLHVQKNGEGKWVITTIYPRIAPAGSII
PNINNGGFTNYLDPFLEQEFKEEAFDIRRMLEHFSLTLAQHLDEIQMVQFGEVIDEIGID
VGLDEQQKIWMYEVNWRPGCPPAFYLELDVVINSIRYAMYLAKNQKQMKKGINQQKQKPQ
PKEQQKPIIAITGSAGKTTSKAFLGSILSRKWKIFESKDYWNTTEHTKKHAEEINASHEA
VVLEYGMAYPGIITNHCSIIQPNISVITNIGLAHVGNFDGDIKGVAKAKSELIHGMDQSG
LLILNKDDDNSRFLETQQFKGKIITVGIHRPADYKAYDIQYKDVGMTFKIKLQGQEITMY
IPILGEHHVYNALNAIAVADTLGFSPIDIQAGLNFKKPPRRLTIYNCRDSITVIDDTVHS
HPQGVRAAIDVLTNIAKKRKIAIIGQMRELGDLREEEYRKLGEYVYEQDIDLFITYGFRT
EEMGAAAKAIGMDPAKVYHFLNKDELHALLEKIIEPHDTILVKGASKTNMFETVKFLDDT
YKV
NT seq
2172 nt
NT seq
+upstream
nt +downstream
nt
atgacaattatcggaatgttgcatcatcgacttgacccaacaaccgttattaagtcatat
gcatatgcagccgttgcaaaagcggaaggggctcaatttttttattttacaccaaaaagc
gtagattttaacaaacggtccataagaggaaaggtatatgaaaatggtgaatggctcgaa
aaaataatgcctttcccagatgtagtttataatgcaggtagtccagaaaaattatcagtt
tcaaaggaaattattgataaattaaaagatgaaatcccatttacaacgcattctataggg
aataaatggaacgtaatgaagcgtctaaaggaagcaaaggaatttgataaatatttaatt
ccaacagaaattgtaaaaaatgctgagttatttcataaatttttttcttactataaaaaa
gtcgtatttaagccgatagatggtcgcaagggaaaaggcatttattttataacgaaagca
gatagtacgaattttgaggtaagaaaggatagtgaaaaccgagtatattccaagcaccag
ctagatgaattaattaaagggcaacttgctacaggaacctttatcatgcagccgtatatc
caatctaaaacgaaggcaggtcaggtttatgatttccgtcttcatgtgcaaaaaaatggc
gagggtaaatgggttatcactactatttatccgagaattgcccctgctggttcgattatt
ccgaatatcaataatggaggatttacgaattatttagatcctttcttggagcaggaattc
aaggaagaggcctttgatattcgacgtatgctagagcatttctccttaacattagctcaa
cacctagatgaaattcagatggtgcaatttggagaggtgattgatgaaattgggattgat
gtgggcttagatgagcaacaaaaaatttggatgtatgaagtaaactggcgaccaggttgt
cctcctgctttttatttagaactagatgttgtgattaattctattcgctatgcaatgtat
cttgcgaaaaatcaaaaacaaatgaaaaaaggaattaatcaacaaaaacaaaaaccacaa
ccaaaagagcagcagaaaccgattattgctattacgggaagtgctgggaaaacaacatct
aaagcttttctaggctcaatattatcgagaaaatggaaaattttcgagtcgaaagattat
tggaatacgactgagcatacaaaaaaacatgctgaggaaattaacgcttctcatgaggcg
gtagtgcttgagtatggaatggcttacccaggtatcattacgaatcactgtagtattatt
caaccgaatattagtgttattacaaatattgggttagcacacgttggtaattttgatgga
gatattaagggtgtggcaaaggcaaaatctgaattaattcatggaatggatcaaagtggt
ttattaatcttgaataaggatgatgataactctaggtttttagaaacacagcaatttaaa
gggaaaattataacggttggtattcatcgtcccgcagattataaagcctatgatattcaa
tataaggatgttggtatgacctttaaaataaagcttcagggacaggaaataacaatgtat
attcctattttaggagaacatcatgtttataatgctctgaatgccatcgcagttgcggat
accttagggtttagtccaatagatattcaagcagggctgaatttcaaaaaaccgcctaga
cggcttacgatttataattgtcgtgatagtattactgttattgatgatacagttcattct
catcctcagggtgtgcgtgcggcgattgacgtactgacaaatatagcgaagaaacgtaaa
attgccatcattggtcaaatgcgagaattaggggatttgcgagaagaagagtatcgtaag
ttgggtgaatatgtttatgagcaggacatagatctttttatcacatatggctttagaacg
gaggaaatgggcgccgctgcaaaggcaatagggatggacccagcgaaagtttatcatttt
ctaaataaagatgagctccatgcactgttagagaaaataatcgaaccacatgacaccatt
ttagttaagggtgctagtaaaacgaatatgtttgagacagttaaatttttagatgacact
tataaggtgtaa
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