Legionella pneumophila subsp. pneumophila HL06041035 (serogroup 1): LPV_1455
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Entry
LPV_1455 CDS
T02174
Symbol
folC
Name
(GenBank) bifunctional folylpolyglutamate synthase and dihydrofolate synthase
KO
K11754
dihydrofolate synthase / folylpolyglutamate synthase [EC:
6.3.2.12
6.3.2.17
]
Organism
lph
Legionella pneumophila subsp. pneumophila HL06041035 (serogroup 1)
Pathway
lph00790
Folate biosynthesis
lph01100
Metabolic pathways
lph01240
Biosynthesis of cofactors
Brite
KEGG Orthology (KO) [BR:
lph00001
]
09100 Metabolism
09108 Metabolism of cofactors and vitamins
00790 Folate biosynthesis
LPV_1455 (folC)
Enzymes [BR:
lph01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.12 dihydrofolate synthase
LPV_1455 (folC)
6.3.2.17 tetrahydrofolate synthase
LPV_1455 (folC)
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GFIT
Motif
Pfam:
Mur_ligase_C
Mur_ligase_M
M157
Fe-ADH
Motif
Other DBs
NCBI-ProteinID:
CCD08609
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Position
1468780..1470066
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AA seq
428 aa
AA seq
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MHTPWSEWDLNHWLTHLETRNTQEIQLGLTRVLTVAQKLNLQRPNCKVITVAGTNGKGST
VTALETIYHQSGFRVGTYTSPHLLVFNERIRINLIPIQDKDLCKAFSVIEEARYPTNLTY
FEMATLAALWYFKQHDLDLIILEVGMGGRLDATNIVDTDLAIITTIDFDHQNFLGDTLEL
IGYEKAGILRKNKPFIYADLSPPKSVVEVALQLGASSYLYGKDYFYQEEADHWGVTCQGK
PFEQLTRPKIQLRSAAAAVMACHLMQNDLPVSYKNLKKAMELIYIPGRLQLQKGKTDILY
DVSHNPQSVRLLADTVKKINVKGQIHAVFSALKDKDLYGLIMPLRDCVNRWYPAQLHNKR
AASQEELLSVFREAEIFLDVCYNDPFTAFEMALKQASDDDLIIVYGSFFTVSHVMAAQHN
LLEQKENQ
NT seq
1287 nt
NT seq
+upstream
nt +downstream
nt
ttgcacacgccatggagtgaatgggatttaaatcactggttgactcatttggaaaccaga
aatacccaggaaatacagcttggtttgaccagagttttgactgtagcgcagaaattaaat
ttgcagcgaccaaattgcaaggtaataacggttgcaggaacaaacggtaaaggttctaca
gtcacagcacttgaaacaatctatcaccagtcaggttttagagttggtacctatacgtcg
ccccatcttcttgtgtttaatgaacgtattcgaattaatttaataccgattcaagataaa
gatttatgtaaggctttttctgtgattgaagaagcacgttaccctaccaatttaacctat
tttgaaatggcaacacttgctgccttatggtatttcaaacagcatgatctggatctgata
attcttgaagtaggcatgggaggacggttggatgctacaaacattgttgatactgattta
gcgatcattactactatcgactttgatcatcagaattttcttggtgacacacttgagttg
atagggtatgagaaagccggaatactacgaaaaaataaaccttttatctacgcggatctc
tcaccaccaaaaagtgtcgttgaggttgcattacaacttggagcatcatcttatttatac
ggtaaagactatttttatcaggaggaagctgaccattggggggttacctgtcaaggtaag
ccatttgagcaattgaccaggccaaaaattcaacttcgttctgcggcagcagctgtaatg
gcttgtcatttgatgcaaaatgatttgcctgtatcctataagaatctaaagaaagcgatg
gagctcatttatatcccggggcggttgcaattacaaaaaggaaagactgatattttgtac
gatgtatctcataatccgcagtcagttcgattacttgctgatacagtaaaaaaaatcaat
gtaaaagggcaaattcatgctgttttctccgctttaaaggataaagatctttatggattg
attatgcctttaagggattgtgttaatcgatggtatcctgcacaattacataataagcgc
gctgcaagtcaagaggaattgctttctgtattcagggaagcagaaatttttctagatgtt
tgttataatgacccatttacagcttttgaaatggcattaaagcaagcatcagatgacgat
ttaattattgtttatggttcattttttacggttagtcatgtaatggctgcccaacataat
cttttggagcagaaggagaatcaatga
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