Lactiplantibacillus plantarum WCFS1: lp_2336
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Entry
lp_2336 CDS
T00115
Symbol
gshAB
Name
(GenBank) glutathione biosynthesis bifunctional protein: glutamate-cysteine ligase; glutathione synthetase
KO
K01919
glutamate--cysteine ligase [EC:
6.3.2.2
]
Organism
lpl
Lactiplantibacillus plantarum WCFS1
Pathway
lpl00270
Cysteine and methionine metabolism
lpl00480
Glutathione metabolism
lpl01100
Metabolic pathways
lpl01240
Biosynthesis of cofactors
Brite
KEGG Orthology (KO) [BR:
lpl00001
]
09100 Metabolism
09105 Amino acid metabolism
00270 Cysteine and methionine metabolism
lp_2336 (gshAB)
09106 Metabolism of other amino acids
00480 Glutathione metabolism
lp_2336 (gshAB)
Enzymes [BR:
lpl01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.2 glutamate---cysteine ligase
lp_2336 (gshAB)
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Gene cluster
GFIT
Motif
Pfam:
Glu_cys_ligase
ATP-grasp_6
ATPgrasp_ST
Motif
Other DBs
NCBI-ProteinID:
CCC79530
UniProt:
Q88UW5
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Position
complement(2111070..2113325)
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AA seq
751 aa
AA seq
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MELDAVGKAIVQYHLVPLVHQANLGLEVTMHRVDAHGHLATTAHPQAFGSAQQNHQLRPG
FSASALKFTTPVRRDIPALMAYLKGLNTAARRSLDADERLWPLSSTPVLPDDLTNVPLAD
VDQVSYQRRRDLARKYELQRLMTTGSHVNMSLNEALFTRLYTETFHQQYHSYVDFRNAIY
LKVAQGLVRMNWLIQYLFGASPRLAVTDTTSRPQRSSVQHPDGRYSQVTGDYTSIDRYVA
KLTAAVRQQQLLSVNDFDGPVRLRSNGQLAMMARQGVYYLEYRGLDLDPTSPVGVDANAV
AFVRLLASYFVMMPALPAKMVSQVNAQADQLTRQVLGENPTTASAQAVPAVQVLDALADF
VKTYGLPNEDAVLLKQLKSWVTDPKKTLSAQIAMQADPLAWALERAARYQESSNERPFEL
AGFTALDLSSQQLAQQALTRGVQVDVVDPHANILRLTKLGRSQLVVNGSGTDLNPQALTT
VLTHKAAAKQILAEHGVPVPASQTYHTANQLIADYDRYVQAGGIVLKAADESHKVIVFRI
MPERGLFEQVVRQLFEQTSAVMAEEVVVASSYRFLVIDSRVQAIVERIPANIVGDGRSTV
KTLLDRKNGRALRGTAFKWPQSALQLGTIERYRLDSYHLTLDSVVSRGTQILLREDATFG
NGADVLDATADMHQSYVQAVEKLVADLHLAVAGVDVMIPNLYAELVPEHPEMAVYLGIHA
APYLYPHLFPMFGTAQPVAGQLLDALFKNED
NT seq
2256 nt
NT seq
+upstream
nt +downstream
nt
atggaattagatgccgttggtaaggcaattgtacagtatcacttagtcccactcgttcat
caggctaatttaggactagaggtcaccatgcaccgggtggacgcccatggtcacttagcg
acgacagcacacccgcaagcgtttggatcagcgcaacaaaatcatcagttacgtccgggc
ttttccgcaagtgctttaaagtttactacgccggtgcgtcgtgacattcctgcattgatg
gcgtatctgaagggcttgaataccgcagcacggcggtcactcgatgcggacgaacgactt
tggccactgtcgagtacgcctgtgttgccggatgatctaacgaacgtaccactggctgat
gttgatcaagtcagctatcagcgtcgtcgcgacttagctcgtaagtatgagttacagcga
ttaatgacgactggtagtcacgtgaatatgagcttgaatgaagctttattcacccgttta
tatactgagactttccatcagcagtatcacagttatgttgactttcgcaatgcaatttat
ctgaaagtcgctcagggattggtgcgcatgaactggctgattcagtatttatttggcgct
tcaccacgcctagccgttacggatactacgagtcgtccacagcgcagtagtgttcaacat
cccgatggtcgctacagtcaagtgacgggagactatacgtcaattgatcgctacgtggcc
aagttgacggcggctgttcgtcaacagcagttgttgtctgtcaatgattttgacgggcca
gttcggcttcggagtaatgggcagctagctatgatggcccggcagggggtctattatctt
gaataccggggcttggatctcgatccaactagtccagtcggggtggacgcgaacgcggtg
gcatttgttcgtttgttggcgagttatttcgtaatgatgccggcacttccagctaagatg
gtatcccaagtcaacgctcaagctgaccaattgacccgtcaagttttgggtgaaaatcca
acgacggctagtgctcaggccgtgccggctgttcaagttttagatgcacttgctgatttt
gttaaaacctatggcctaccaaatgaagatgccgtgttactcaaacagttgaagtcgtgg
gtcactgatccaaagaagacgctgagtgcgcagattgccatgcaagccgatccgttagca
tgggcactcgaacgggctgcacgctatcaggaatcgagcaatgaacgtccgtttgaactt
gcgggctttaccgcgctagatctatcgagccagcaactagcccagcaggccttgacgcgg
ggagtgcaggtggacgttgttgacccacacgctaacattttacgattgactaagttagga
cggtcgcaattagttgtgaatgggagcggaacggatttaaatccacaggcgctaacgacc
gtactgacacataaagcagcggccaaacaaattctggctgagcacggggttccggtgccg
gcttcacagacatatcatacagctaatcagttgattgctgattatgatcggtacgttcaa
gctggtgggatcgtattaaaagcggcggatgagtcgcacaaagtaattgtctttcggatt
atgcccgaacgcggactgtttgaacaagtcgtccggcaactattcgagcaaacgtccgcg
gtaatggccgaggaagtggtagtcgcatcaagttatcgctttttggttatcgatagtcgt
gtgcaagcaatcgtcgaacgaattccagccaatattgttggtgatggtcgctcaacggtc
aagacgttacttgatcgcaaaaatggtcgagcgttgcgcgggaccgcttttaagtggcct
caatcagcgctacagttaggaacgatcgaacggtatcgcctggactcatatcacttgacc
ttagattctgtggtcagccggggaactcagatcttattacgagaggatgcgacttttggt
aacggggcggacgtgctagacgcgacggctgatatgcatcaatcctatgtgcaggcggtg
gaaaagttggtagcagacttacacttggcggtcgctggggtcgacgtgatgattcccaat
ctctatgccgaattagtgccagagcatcctgaaatggcggtatacttgggtattcatgcg
gcgccgtacttgtatccgcacttgttcccaatgtttggtactgcccaaccagtggcgggg
cagttgttggatgcattgtttaaaaatgaagattaa
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