Legionella pneumophila subsp. pneumophila Philadelphia 1 (serogroup 1): lpg2581
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Entry
lpg2581 CDS
T00199
Name
(GenBank) 2-oxoisovalerate dehydrogenase, E1 component, alpha and beta fusion
KO
K11381
2-oxoisovalerate dehydrogenase E1 component [EC:
1.2.4.4
]
Organism
lpn
Legionella pneumophila subsp. pneumophila Philadelphia 1 (serogroup 1)
Pathway
lpn00280
Valine, leucine and isoleucine degradation
lpn00640
Propanoate metabolism
lpn00785
Lipoic acid metabolism
lpn01100
Metabolic pathways
lpn01110
Biosynthesis of secondary metabolites
lpn01210
2-Oxocarboxylic acid metabolism
Brite
KEGG Orthology (KO) [BR:
lpn00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00640 Propanoate metabolism
lpg2581
09105 Amino acid metabolism
00280 Valine, leucine and isoleucine degradation
lpg2581
09108 Metabolism of cofactors and vitamins
00785 Lipoic acid metabolism
lpg2581
Enzymes [BR:
lpn01000
]
1. Oxidoreductases
1.2 Acting on the aldehyde or oxo group of donors
1.2.4 With a disulfide as acceptor
1.2.4.4 3-methyl-2-oxobutanoate dehydrogenase (2-methylpropanoyl-transferring)
lpg2581
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Gene cluster
GFIT
Motif
Pfam:
E1_dh
Transket_pyr
Transketolase_C
CARDS-D2_trefoil
PFOR_II
Motif
Other DBs
NCBI-ProteinID:
AAU28639
Pasteur:
lpg2581
UniProt:
Q5ZSD8
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All DBs
Position
complement(2908957..2911227)
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AA seq
756 aa
AA seq
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MVIAQFKQGVVMLDRASVVDEQFLKRVLQGDFPQLRSSMSPDTAELDKKTAIEFFDSQIK
SRLLDIIARQLKEKGLSFYTIGSSGHEGNAVLGQVFRASDMAFLHYRSGAFFLQRAKQLP
GIDGVKDILLSLVAAASDPISGGRHKVFGSVPLNIPPQTSTIASHLPKALGAALSITRAR
ELGLPSKLTPDSVILCSFGDASTNHATSQATLNACSWITQQNYPLPIVFICEDNGIGISV
PTPSSWIKSSVSSRPGIHYIECDGLNIADVFAKAQEADYLARVKKQPVFLHMRCVRLLGH
AGSDIESQYNTQEEIEQREANDPLLHTAGILYREGWMSLQAMVELYQDNRALIEAKALEA
IREPRMSSAEEIMASIVPRIDKKQKYSLPDDNRRAQVFAGAYNQLTLKRNLCQQINFALT
DLMMQYPNMLIFGEDVGKKGGVYRVTADLQARFGQRRVFDTLLDETTIIGTAIGLAHNGF
IPVPEIQFLAYLHNAEDQLRGEASTLSFFSSGQYQNPMVLRIASLAYQKGFGGHFHNDNS
IAVLRDLPGVIVACPSNGPDAAKMLRTCMRLAYEEGRVVVFLEPIALYMTKDLYSPGDNG
WLFEYPSPDEMISQGEVGVYGEGDTVILTYANGYYLSRQAEKVLREAHNISVKIIDLRWL
SPLPKDAILKEIAKAKRILIVDEGRQSGSISEGLMTLLMEEASPRLKIKRITGKDCFIPL
GTAWQYLLPSQESIIDAVIALQSDKREKESGRLVVS
NT seq
2271 nt
NT seq
+upstream
nt +downstream
nt
ctggtcattgcgcaatttaaacagggtgtggtgatgttagatagagcaagtgtagtggat
gaacaatttctgaaaagagtgttgcaaggggatttcccacaattaagaagcagcatgagc
cccgatacagcagagttggacaagaaaactgctatagaattttttgactcacaaattaaa
tcccggcttcttgatattattgcgagacaattaaaggaaaaaggcctctctttttatacg
ataggaagtagtggtcatgaaggcaatgcggttttgggtcaggtttttagagcgagtgat
atggcgtttttgcactatcgcagcggtgcctttttcttgcaacgagcaaagcaattacct
ggaatcgatggagtaaaggatattttattgtcattagtggctgcggcaagtgatcctatc
tcagggggcaggcataaagtctttggcagcgtccctttaaatatcccgccgcaaacatcg
actatcgcatctcatttaccaaaagctttaggcgctgctttatcaattaccagagcgcga
gagttaggattgccaagtaaactgacgcctgattccgtgatactttgttcctttggtgat
gcttcaaccaaccatgcaacgagccaagccacattgaatgcttgctcctggataacccag
caaaactatccactccccattgtgttcatttgtgaagataatggaatcggtatttcagta
cctactccatccagttggattaagtcatccgtttcttctcgtccaggaatacattacatt
gagtgtgatggattaaacattgcggatgtttttgccaaagcgcaggaagcggactatttg
gcaagagtaaaaaaacaacccgtgttcttgcacatgcgttgtgtccgtttgttgggccat
gccggttctgatattgaatcgcaatacaacactcaggaagaaattgagcaacgagaagca
aacgaccctttattgcatacagcaggaattttgtacagagaaggttggatgagtttacag
gcaatggttgagctttatcaggacaaccgggctttaattgaagccaaggcactcgaggca
atcagagaacccagaatgagttctgctgaagaaataatggcttcaattgtcccacgaatt
gataaaaagcaaaaatactcattgccagatgataataggcgagcgcaagtatttgccgga
gcttataatcaactcaccctaaagcgtaatttatgccagcagatcaattttgccttgacc
gatctgatgatgcagtatcctaatatgttgatttttggagaagacgtaggaaagaaaggt
ggagtttatcgagttacagctgatttacaggctcgttttgggcaacgcagggtttttgat
acccttctcgatgaaacgaccattataggtactgctattggtttggcacataatggcttt
attcctgttccggaaattcagttcttagcttatctgcataatgccgaagatcaattacgt
ggagaagcatccactttatcttttttttcaagtggccaatatcaaaaccctatggtactt
cgaatcgcctctcttgcttatcagaagggatttggcggtcattttcataacgataattcg
atagccgttttacgcgatttgccaggggttatagtggcttgcccctctaatggcccggac
gcagcaaaaatgttgagaacatgtatgcgccttgcctatgaggaagggcgggttgtcgtg
tttttagagcccattgccctctacatgaccaaggatttgtatagcccgggagataatggg
tggttatttgaatacccgtcacctgatgaaatgatttctcaaggagaggttggcgtatat
ggggagggggatactgttattttaacatatgccaatggatattatttatctcgccaggcg
gaaaaggtcttgcgtgaagcacataatatttctgttaagatcattgatttgcgctggctc
agccccttgccaaaagacgccattttaaaagaaattgccaaggcaaaacgtattttaatt
gttgatgagggtagacaaagcggctcaattagtgaaggattgatgacattattgatggaa
gaggcttcgccacggttaaaaataaagcggattacgggcaaagattgcttcataccatta
ggaactgcttggcagtatttattgccaagtcaggaaagtattatagacgcggtaatcgca
ttacagtcagataaaagggagaaggaaagtggacgacttgttgtttcttga
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