Legionella pneumophila subsp. pneumophila Philadelphia 1 (serogroup 1): lpg2618
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Entry
lpg2618 CDS
T00199
Symbol
murF
Name
(GenBank) UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diaminopimelate-D-alanyl-D-alanyl ligase
KO
K01929
UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase [EC:
6.3.2.10
]
Organism
lpn
Legionella pneumophila subsp. pneumophila Philadelphia 1 (serogroup 1)
Pathway
lpn00300
Lysine biosynthesis
lpn00550
Peptidoglycan biosynthesis
lpn01100
Metabolic pathways
lpn01502
Vancomycin resistance
Brite
KEGG Orthology (KO) [BR:
lpn00001
]
09100 Metabolism
09105 Amino acid metabolism
00300 Lysine biosynthesis
lpg2618 (murF)
09107 Glycan biosynthesis and metabolism
00550 Peptidoglycan biosynthesis
lpg2618 (murF)
09160 Human Diseases
09175 Drug resistance: antimicrobial
01502 Vancomycin resistance
lpg2618 (murF)
Enzymes [BR:
lpn01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.10 UDP-N-acetylmuramoyl-tripeptide---D-alanyl-D-alanine ligase
lpg2618 (murF)
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Gene cluster
GFIT
Motif
Pfam:
Mur_ligase_M
Mur_ligase_C
Mur_ligase
CBM_20
Motif
Other DBs
NCBI-ProteinID:
AAU28676
Pasteur:
lpg2618
UniProt:
Q5ZSA1
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All DBs
Position
complement(2954902..2956287)
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AA seq
461 aa
AA seq
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MSLSVSTLVFSTSQNTMNLITIASLLSQSCQINADITGVSIDTRTLKPGNLFFAIVGERF
DGHDFIKEAEAKGASAAVVNRSIDGVHIPQFVVASPLMALAKIAAAHRQEMSCPIIALTG
SNGKTTVKEMIATILPQPSHATKGNLNNHIGVPLSMLALNKQHRYAVFELGANHPGEIAH
TVGIVQPDVSLINNIAPAHVEGFGSIDGVARSKGEIHQGLSPTGVAIVNDDDAYAHFWDD
LIADKKILRFSSLHPADIYAQDIRLDTHGRAHFTLVLPNSRVEIELQVPGLHNVRNALAA
AACCYAVGISGNDIQRGLAHFGGVKGRMTMLSGQNQSTVIDDTYNANLRSVLTALEVLSG
RPGRKIFVFGDMGELGEWTTQHHREVGVAARQLGIDKLMSCGLHSELASQAFGEGGQHFC
SQEELIEVVKNDLTPDTTVLVKGSRSSAMENVVHRLVQVEG
NT seq
1386 nt
NT seq
+upstream
nt +downstream
nt
gtgagcctgagtgttagtacactagtcttttcgacatcacaaaatactatgaacctaatt
actattgcgtcacttctttctcagtcttgccagattaatgccgacattactggtgttagt
atagatacccgcacattaaagccaggaaatttattttttgcgatagtgggggaacgcttt
gatggtcatgattttattaaagaagccgaggctaaaggcgcttcagctgctgtagttaat
cgatcgattgacggtgttcatattcctcaattcgtggttgccagtcctttaatggctttg
gccaaaattgctgcggcacatcgacaggaaatgagttgccctattattgctttaacaggg
tcaaatggaaaaaccactgtcaaagagatgatagcgactattttaccgcagccatcacat
gctacgaaaggcaatttaaataatcacataggggttcctttaagcatgttagctttaaat
aagcagcaccgctatgctgtttttgagttgggagccaatcatcccggagaaatagcacat
acggtagggatagtgcagcctgatgtgtctttaattaataatattgccccggcacatgtc
gaaggctttggatcaatagacggagtcgctcgttccaaaggtgaaatccatcaaggctta
tccccgactggtgttgctatagtcaatgatgatgatgcctacgctcacttttgggatgat
ttgattgctgataaaaaaatattacgtttttcctcacttcatcctgcagatatttacgcc
caggatatacgcttggatacccatgggcgagctcattttacattggttttacctaatagc
agagtggagattgagttacaagtaccaggtttgcacaatgtccgaaatgctttggctgcc
gcagcttgttgttatgctgtaggaatatcaggcaatgacattcaaagaggactggctcat
tttggtggtgtaaaaggtcggatgacgatgttgtcagggcaaaatcaatcaacagttatt
gatgatacatacaatgctaatttacgctctgtcttaacagccctggaagttttatctggg
cgcccaggaagaaaaatttttgtattcggtgatatgggagagttgggtgaatggacgaca
caacatcacagagaagttggcgtagcggctcgccagctgggaatagataagttgatgagt
tgcggtttacatagtgaactggcatcccaggcgtttggtgagggaggtcagcatttttgc
agtcaagaagagttgattgaagtggtaaaaaatgatttaacacctgataccacggtattg
gtaaaaggatccaggtccagtgctatggaaaatgttgtgcaccggttggttcaggtagag
ggctaa
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