Leclercia pneumoniae: KQ929_17205
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Entry
KQ929_17205 CDS
T08189
Symbol
murF
Name
(GenBank) UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase
KO
K01929
UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase [EC:
6.3.2.10
]
Organism
lpnu
Leclercia pneumoniae
Pathway
lpnu00300
Lysine biosynthesis
lpnu00550
Peptidoglycan biosynthesis
lpnu01100
Metabolic pathways
lpnu01502
Vancomycin resistance
Brite
KEGG Orthology (KO) [BR:
lpnu00001
]
09100 Metabolism
09105 Amino acid metabolism
00300 Lysine biosynthesis
KQ929_17205 (murF)
09107 Glycan biosynthesis and metabolism
00550 Peptidoglycan biosynthesis
KQ929_17205 (murF)
09160 Human Diseases
09175 Drug resistance: antimicrobial
01502 Vancomycin resistance
KQ929_17205 (murF)
Enzymes [BR:
lpnu01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.10 UDP-N-acetylmuramoyl-tripeptide---D-alanyl-D-alanine ligase
KQ929_17205 (murF)
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Gene cluster
GFIT
Motif
Pfam:
Mur_ligase_M
Mur_ligase_C
Mur_ligase
LpxD
Motif
Other DBs
NCBI-ProteinID:
QWW78956
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Position
complement(3511060..3512418)
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AA seq
452 aa
AA seq
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MISVSLSQLAGILHGELQGQDLTCDAVTTDTRKITPGCLFVALKGERFDAHDFADQAKEA
GAGALLVSRKLNVDLPQVVVKDTRQAFGELAAWVRQQVPTRIVALTGSSGKTSVKEMTAA
ILSQCGNTLYTAGNLNNDIGVPMTLLRLTPEHEYAVIELGANHQGEIAWTVSLTKPEAAL
VNNLAAAHLEGFGSLEGVAKAKGEIYTGLPQNGIAIMNADNNDQLNWKSVIGDRKTWRFS
PNAANSDFTATNIHVTSHGTEFTLQTPTGSTDVLLPLPGRHNIANALAATALAMAVGAPL
SAIKTGLANLTAVPGRLFPVPLGENKLLLDDSYNANVGSMTAAVQVLSEMPGYRVLVVGD
MAELGDESVACHRQVGEAAKASGIDRVLSTGALSQTLSEASGAGEHFADKAALITRLKAL
IQEKQIITVLVKGSRSAAMEDVVRVLQENGTC
NT seq
1359 nt
NT seq
+upstream
nt +downstream
nt
atgattagcgtatcgctaagccaactcgccggcattttgcacggtgaactgcagggacag
gatctgacctgtgatgcggtaacaacggacacccgtaaaatcaccccagggtgcctgttt
gtggcgctgaagggcgagcgttttgacgctcatgattttgccgatcaagccaaagaggcc
ggcgctggcgcactgttagtgagtcgtaagctgaatgtcgatttgccccaggtggtggtg
aaagatacccgccaggcgtttggtgaactggcggcatgggtgcgccaacaggtccctacg
cggatcgtggcgctgaccggttcatccggtaaaacttcggttaaagagatgaccgcggcc
attttgagccaatgcggtaacaccctctacactgccgggaacctgaataatgacatcggt
gtgccgatgactctgctgcgtctgacgccagagcatgagtatgccgtgattgagcttggc
gctaaccaccagggagaaatcgcctggaccgtcagcctgactaaaccggaggcggcgtta
gtcaataatctggcggccgctcacctcgaagggtttggctcgctcgaaggcgtggcgaaa
gcgaagggcgaaatctataccggtctgccgcagaacggtatcgccatcatgaacgccgat
aataacgaccagttgaactggaagagcgtgattggcgatcgcaaaacctggcgattttca
ccgaatgctgccaacagcgactttacggcaaccaatatccatgtgacctcgcacggtaca
gagttcaccttacaaacgccaaccggcagcacggacgttctgctgccgttgccggggcgc
cataacatcgccaacgcgctggccgcgacggcgctggccatggcggtcggtgctcccctg
agcgctatcaaaaccggactggcaaatttgaccgcggtaccaggtcgtctgttcccggtc
ccactgggtgaaaacaaactgctgctggacgactcctataacgccaacgtcgggtcgatg
accgctgcggttcaggtgctgtccgaaatgccgggctaccgcgtgctggtggtcggtgac
atggcagagctgggtgatgaaagcgtagcgtgtcaccgccaggtgggggaagcagcgaaa
gcttcaggtattgatcgcgtgttaagcaccggagcattaagccagacacttagtgaggca
agcggcgcaggtgagcactttgctgacaaagccgccctgatcacccgcctgaaggcgttg
attcaggaaaaacaaatcatcaccgttttggtgaaaggttcacgtagcgcagccatggaa
gacgttgtgcgcgtattacaggagaatgggacatgttag
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