Legionella pneumophila subsp. pneumophila Lorraine (serogroup 1): LPO_1913
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Entry
LPO_1913 CDS
T02175
Symbol
gshA
Name
(GenBank) Glutamate--cysteine ligase
KO
K01919
glutamate--cysteine ligase [EC:
6.3.2.2
]
Organism
lpo
Legionella pneumophila subsp. pneumophila Lorraine (serogroup 1)
Pathway
lpo00270
Cysteine and methionine metabolism
lpo00480
Glutathione metabolism
lpo01100
Metabolic pathways
lpo01240
Biosynthesis of cofactors
Module
lpo_M00118
Glutathione biosynthesis, glutamate => glutathione
Brite
KEGG Orthology (KO) [BR:
lpo00001
]
09100 Metabolism
09105 Amino acid metabolism
00270 Cysteine and methionine metabolism
LPO_1913 (gshA)
09106 Metabolism of other amino acids
00480 Glutathione metabolism
LPO_1913 (gshA)
Enzymes [BR:
lpo01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.2 glutamate---cysteine ligase
LPO_1913 (gshA)
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Motif
Pfam:
GshA
RimK
Motif
Other DBs
NCBI-ProteinID:
CCD05925
UniProt:
A0AAN5SRZ7
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Position
complement(1977827..1979122)
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AA seq
431 aa
AA seq
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MNKHEIPVPHLTTAHSGPLYHVEKIILNKLAEIESWFRKKWQETPAPLTSSVDLRHAGFK
LAPVDTNLFPAGFNNLNPEFLPLCIQAAQSALIEYIPDCTKILLLPESHTRNKYYLQSLN
VLKTIFVKAGFIVRIGSLDPDIKEPTEIILEQGETLLIEPLQRQGDKVGLDNFSPCLLLL
NNDLSSGVPEILQDVQQRIRPTAKLGWASRLKSSHFQFFEEVAIEFAELVGIDPWLINPY
FSAIEGVDFMAQEGIETLAQEVDKILSLINDKYTTYGIENKPFAVVKADNGTYGMSVMMV
HNGDEIRQLNRKQRTRMSTSKGSRKVDRVIIQEGVYTFETMPDGSVAEPVVYMIGQFVVG
GFYRVHKGRGIDENLNAPGMHFEPLAFAQACNMPCDDLEVVDCPNRFYVYGVIARLAALA
AAREIAAIGGE
NT seq
1296 nt
NT seq
+upstream
nt +downstream
nt
atgaataagcatgaaatccccgttccgcatctgactactgctcattcaggtcctttgtat
catgtggaaaaaataatattaaataaacttgctgaaatagaatcctggttcagaaaaaag
tggcaggaaacaccggcacctctaacgtcatctgttgatttgcgacatgctggctttaaa
ttggctcccgtcgataccaatttatttccagctggttttaataatttaaacccggagttc
cttcccctgtgtatacaagctgctcaatctgccttgatagagtatatccctgattgtact
aaaattttgcttcttccagaaagccatactcggaataagtattatttacagagtttgaat
gtattaaaaacaatttttgtaaaagctggttttatagttcgaataggcagtttagatcca
gacattaaagaacctacagaaataatactcgaacaaggtgaaactttattaattgaacca
ttacaaagacaaggtgataaggtaggactggataatttcagcccttgccttttgttattg
aataacgatttgtcttcaggcgttcctgaaatattacaggatgtgcaacagcgaattaga
cctacagccaaattaggatgggcttctcgattaaaatcgagtcattttcaattttttgaa
gaagtagctattgagtttgctgaattagtcggtattgatccgtggttaattaatccctat
tttagcgctatagagggggtcgattttatggcccaggaagggattgaaaccttagctcaa
gaagtcgataagatattatcgttaataaacgataaatacactacttacggaatagaaaat
aaaccgttcgcagtagtaaaggcagataatggtacttatggcatgagcgttatgatggtt
cataatggagatgaaattcgacaattgaatagaaagcagcgtaccaggatgtctaccagt
aaaggaagcaggaaggtagacagagtcattattcaggaaggtgtttatacttttgaaacg
atgcctgatggttctgttgctgaacctgtagtttatatgattggtcaatttgttgttggt
ggattttatcgtgttcataaaggcagaggaattgatgagaacctcaatgctccaggcatg
cattttgagccgttagctttcgcacaggcttgtaatatgccatgtgatgatttagaggta
gttgactgcccaaatcgtttttatgtttatggggttatagctcgtttggctgcactggct
gcagctcgagaaattgctgcaattggaggcgaatga
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