Legionella pneumophila subsp. pneumophila Lorraine (serogroup 1): LPO_2846
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Entry
LPO_2846 CDS
T02175
Name
(GenBank) 2-oxoisovalerate dehydrogenase, E1 component, alpha and beta fusion
KO
K11381
2-oxoisovalerate dehydrogenase E1 component [EC:
1.2.4.4
]
Organism
lpo
Legionella pneumophila subsp. pneumophila Lorraine (serogroup 1)
Pathway
lpo00280
Valine, leucine and isoleucine degradation
lpo00640
Propanoate metabolism
lpo00785
Lipoic acid metabolism
lpo01100
Metabolic pathways
lpo01110
Biosynthesis of secondary metabolites
lpo01210
2-Oxocarboxylic acid metabolism
Brite
KEGG Orthology (KO) [BR:
lpo00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00640 Propanoate metabolism
LPO_2846
09105 Amino acid metabolism
00280 Valine, leucine and isoleucine degradation
LPO_2846
09108 Metabolism of cofactors and vitamins
00785 Lipoic acid metabolism
LPO_2846
Enzymes [BR:
lpo01000
]
1. Oxidoreductases
1.2 Acting on the aldehyde or oxo group of donors
1.2.4 With a disulfide as acceptor
1.2.4.4 3-methyl-2-oxobutanoate dehydrogenase (2-methylpropanoyl-transferring)
LPO_2846
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Gene cluster
GFIT
Motif
Pfam:
E1_dh
Transket_pyr
Transketolase_C
PFOR_II
Motif
Other DBs
NCBI-ProteinID:
CCD06794
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Position
complement(2963768..2966005)
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AA seq
745 aa
AA seq
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MLDRASVVDEQFLKRVLQGDFPQLRSSMSPDTAELDKKTAIEFFDSQIKSRLLDIIARQL
KEKGLSFYTIGSSGHEGNAVLGQVFRASDMAFLHYRSGAFFLQRAKQLPGIDGVKDILLS
LVAAASDPISGGRHKVFGSVPLNIPPQTSTIASHLPKALGAALSITRARELGLPSKLAPD
SVILCSFGDASTNHATSQATLNACSWITQQNYPLPIVFICEDNGIGISVPTPSSWIKSSV
SSRPGIHYIECDGLNIADVFAKAQEADYLARVKKQPVFLHMRCVRLLGHAGSDIESQYNT
QEEIEQREANDPLLHTAGILYREGWMSLQAMVELYQDNRALIEAKALEAIREPRMSSAEE
IMASIVPRIDKKQKYSLPDDNRRAQVFAGAYNQLTLKRNLCQQINFALTDLMMQYPNMLI
FGEDVGKKGGVYRVTADLQARFGQRRVFDTLLDETTIIGTAIGLAHNGFIPVPEIQFLAY
LHNAEDQLRGEASTLSFFSSGQYQNPMVLRIASLAYQKGFGGHFHNDNSIAVLRDLPGVI
VACPSNGPDAAKMLRTCMRLAYEEGRVVVFLEPIALYMTKDLYSPGDNGWLFEYPSPDEM
ISQGEVGVYGEGDTVILTYANGYYLSRQAEKVLREAHNISVKIIDLRWLSPLPKDAILKE
IAKAKRILIVDEGRQSGSISEGLMTLLMEEASPRLKIKRITGKDCFIPLGTAWQYLLPSQ
ESIIDAVIALQSDKREKESGRLVVS
NT seq
2238 nt
NT seq
+upstream
nt +downstream
nt
atgttagatagagcaagtgtagtggatgaacaatttctgaaaagagtgttgcaaggggat
ttcccacaattaagaagcagcatgagccccgatacagcagagttggacaagaaaactgct
atagaattttttgattcacaaattaaatcccggcttcttgatattattgcaagacaatta
aaggaaaaaggcctctctttttatacgataggaagtagcggccatgaaggcaatgcggtc
ttgggtcaggtttttagagcgagtgatatggcgtttttgcactatcgcagcggtgccttt
ttcttgcaacgagcaaagcaattacctggaatcgatggagtaaaggatatcttgttgtca
ttagtggctgcggcaagtgatcccatctcagggggcaggcataaagtctttggcagcgtc
cctttaaatatcccgccgcaaacgtcgactatcgcatctcatttaccaaaagctttaggg
gccgctttatcaattacccgggcgagagagttaggattgccaagtaaactggcgcctgat
tctgtgatactttgttcctttggtgatgcttcaaccaaccatgcaacgagccaagccaca
ttgaatgcttgctcttggataacccagcaaaattatccgctaccgattgtgttcatttgt
gaagataatggaatcggtatttcagtacctactccatccagttggattaagtcatctgtc
tcctctcgtccaggaatccattacattgagtgtgatggattaaacattgctgatgtcttt
gccaaagcgcaggaagcggactatttggcaagagtaaaaaaacaacccgtgttcttgcac
atgcgttgtgtccgtttgttgggccatgccggttctgatattgaatcgcaatacaacact
caggaagaaattgagcaacgagaagcaaacgaccctttattgcatacagcaggaattttg
tacagagagggttggatgagtttgcaggcaatggttgaactttatcaggacaatcgggct
ttaattgaagcaaaagcactggaggcaatcagagagcccagaatgagttctgctgaagaa
atcatggcttcgattgtcccacgaattgataaaaagcaaaaatactcattgccagatgat
aatagacgagcgcaagtatttgccggagcttataatcaactcaccctaaagcgtaattta
tgccagcagatcaattttgctttgaccgatctgatgatgcagtatcctaatatgttgatt
tttggtgaagacgtaggaaagaaaggtggagtttatcgagttacagctgatttacaggct
cgttttgggcaacgcagggtttttgatacccttctcgatgaaacgaccattataggtact
gctattggtttggcacataatggctttattcctgttccggaaattcagttcttagcttat
ctgcataatgccgaagatcaattacgtggagaagcatccactttatcttttttttcaagc
ggccaatatcaaaatcctatggtactgcgaatcgcctctcttgcttatcagaagggattt
ggcggtcattttcataacgataattcgatagccgttttacgcgatttgccaggagttata
gtggcttgcccctctaatggcccggacgcagcaaaaatgttgagaacatgtatgcgcctt
gcctatgaggaagggcgggttgtcgtgtttttagagcccatcgccctctacatgaccaag
gatttgtatagcccgggagataatgggtggttatttgaatacccgtcacctgatgaaatg
atttctcaaggagaggttggcgtatatggggagggggatactgttattttaacatatgcc
aatggatattatttatctcgccaggcggaaaaggtcttgcgtgaagcacataatatttct
gttaagatcattgatttgcgctggctcagccccttgccaaaagacgccattttaaaagaa
attgccaaagcaaaacgtattttaattgttgatgagggtagacaaagcggctcaattagt
gaaggattgatgacattattgatggaagaggcttcgccacggttaaaaataaagcggatt
acgggcaaagattgcttcataccattaggaactgcttggcagtatttattgccaagtcag
gaaagtattatagacgcggtaatcgcattacagtcagataaaagggagaaggaaagtgga
cgacttgttgtttcttga
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