Lacticaseibacillus paracasei N1115: AF91_12720
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Entry
AF91_12720 CDS
T03050
Name
(GenBank) UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase
KO
K01929
UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase [EC:
6.3.2.10
]
Organism
lpq
Lacticaseibacillus paracasei N1115
Pathway
lpq00300
Lysine biosynthesis
lpq00550
Peptidoglycan biosynthesis
lpq01100
Metabolic pathways
lpq01502
Vancomycin resistance
Brite
KEGG Orthology (KO) [BR:
lpq00001
]
09100 Metabolism
09105 Amino acid metabolism
00300 Lysine biosynthesis
AF91_12720
09107 Glycan biosynthesis and metabolism
00550 Peptidoglycan biosynthesis
AF91_12720
09160 Human Diseases
09175 Drug resistance: antimicrobial
01502 Vancomycin resistance
AF91_12720
Enzymes [BR:
lpq01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.10 UDP-N-acetylmuramoyl-tripeptide---D-alanyl-D-alanine ligase
AF91_12720
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Gene cluster
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Motif
Pfam:
Mur_ligase_M
Mur_ligase_C
Mur_ligase
Motif
Other DBs
NCBI-ProteinID:
AHJ33964
UniProt:
A0A806LBI4
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All DBs
Position
complement(2480900..2482288)
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AA seq
462 aa
AA seq
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MKMTLAEIARVVKAQPLSEADGSHVVTGLAFDSRKLKPGMLFVPLRGERDGHEFIPVAAT
AGAVATFVAADHLPVTTKLITLVVPDPLKAMQQLAQYYLLMKVNPKVVAITGSNGKTTTK
DMTAAILATQYHVVKTPDNYNNEIGVPMTILSMEPNTEVLVLEMGMDRPGQLHALSTLAE
PDVAVITMIGEAHIEFFKTRDKIADAKMEITDGLKDDGTFIFNGDEPLLQERAKKITQER
ETFGLHPENTIFAHSISGHRNHTEFTVEAWPDLTFSIPIMGEYNVVNALAALLVGRKFHV
KPEIMQKALAHFQVTANRTQWLIGDVGEQILSDVYNANPTAMKAVIHDFSEFTATGRHIA
VLGDMLELGEQSPALHASLAEALDPKEVQVVYLYGSDMKALADALAAKYPADQLHYYPLD
DKEQMTRDLQNDVNHDDMVLLKASHGLHLETVLSALVAGGRA
NT seq
1389 nt
NT seq
+upstream
nt +downstream
nt
atgaagatgacattggcagagattgcgcgagttgtgaaagctcaaccgctctctgaagca
gacgggtcgcatgtggtgaccggactggcttttgattcacgcaaattgaagccgggtatg
ctgtttgtgccgttacgcggtgaacgtgatggtcacgaatttattccggtggctgctacg
gctggcgcagtggcaacatttgttgcagctgatcatttacctgtcaccaccaagctgatt
acgctggtggtgccggatccgttgaaagcgatgcaacaattggcacaatattatctgttg
atgaaagtgaatcccaaagtggtggcgatcaccggcagcaatggcaaaacgacaacgaag
gacatgaccgctgcgatcttggccacacaatatcacgtcgttaaaacccctgataactat
aataatgaaattggcgtgccaatgactattctcagcatggaacccaataccgaagtcttg
gttcttgagatggggatggatcggccagggcaattacatgcactgtcaaccttagctgaa
ccggatgtggccgtgattacgatgatcggggaagcacatattgaatttttcaagacccgg
gataaaattgccgatgccaaaatggaaatcactgatggcctaaaggatgatggtacgttt
atttttaatggtgacgaaccattgttgcaggaacgggcgaagaagatcacgcaggagcgc
gaaacttttggcttgcatcctgaaaatacgatatttgcccattcaatcagcgggcatcgt
aaccacactgagttcacagttgaagcttggcctgatctgacgttctcgattccgattatg
ggtgaatataatgttgtcaatgcgttagcagccctgttagttggccgcaaattccatgtc
aaacccgaaatcatgcaaaaggcattggctcattttcaggtgacggctaaccggacacag
tggttgatcggggatgtgggtgaacagattctaagcgatgtgtataacgccaacccgacc
gcgatgaaagccgtcattcatgattttagcgaatttacggcaactggccgtcacattgca
gtgctgggggatatgctggagcttggtgaacaaagtcccgcgttgcatgcaagtctggca
gaggcactcgatcctaaggaagtgcaggttgtttatctatacggtagcgatatgaaagca
cttgccgatgcattggcagcaaaatatccagccgatcagttgcactattatccgcttgat
gacaaggaacagatgacgcgcgacttacaaaacgatgttaaccatgacgatatggttttg
ttgaaagcgagtcacggattgcatctggaaaccgttttgtcagctttggtcgctggtggt
cgtgcttaa
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