KEGG   Lacticaseibacillus rhamnosus ATCC 8530: LRHK_1781
Entry
LRHK_1781         CDS       T01961                                 
Symbol
purH
Name
(GenBank) phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase
  KO
K00602  phosphoribosylaminoimidazolecarboxamide formyltransferase / IMP cyclohydrolase [EC:2.1.2.3 3.5.4.10]
Organism
lra  Lacticaseibacillus rhamnosus ATCC 8530
Pathway
lra00230  Purine metabolism
lra00670  One carbon pool by folate
lra01100  Metabolic pathways
lra01110  Biosynthesis of secondary metabolites
Module
lra_M00048  De novo purine biosynthesis, PRPP + glutamine => IMP
Brite
KEGG Orthology (KO) [BR:lra00001]
 09100 Metabolism
  09104 Nucleotide metabolism
   00230 Purine metabolism
    LRHK_1781 (purH)
  09108 Metabolism of cofactors and vitamins
   00670 One carbon pool by folate
    LRHK_1781 (purH)
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04147 Exosome [BR:lra04147]
    LRHK_1781 (purH)
Enzymes [BR:lra01000]
 2. Transferases
  2.1  Transferring one-carbon groups
   2.1.2  Hydroxymethyl-, formyl- and related transferases
    2.1.2.3  phosphoribosylaminoimidazolecarboxamide formyltransferase
     LRHK_1781 (purH)
 3. Hydrolases
  3.5  Acting on carbon-nitrogen bonds, other than peptide bonds
   3.5.4  In cyclic amidines
    3.5.4.10  IMP cyclohydrolase
     LRHK_1781 (purH)
Exosome [BR:lra04147]
 Exosomal proteins
  Exosomal proteins of other body fluids (saliva and urine)
   LRHK_1781 (purH)
SSDB
Motif
Pfam: AICARFT_IMPCHas MGS NSP2_assoc Corona_3 DUF440
Other DBs
NCBI-ProteinID: AER64550
LinkDB
Position
complement(1728284..1729807)
AA seq 507 aa
MKRALLSVSDKTGLVPFAKGLVERGFELISTGGTHRALAEAGVAVTGVEAVTGFPEMLDG
RVKTLHPKIHAGILARRDDPAHMQALADHDIQPIDVVCVNLYPFAATIQRAGVTRAEAIE
QIDIGGPSALRAAAKNSDSVWAVVDPADYADVLAGLDQNDADLRQRLAAKVFSVTAAYDA
QIAHYLDPEPFPEQFTPTYHKRQDLRYGENSHQQAAFYVEPNPDPTSLAAAKQLHGKELS
YNNIKDADAALAMLREFKQPAAVAVKHMNPCGIGLGDTLEAAWDKAYAADPMSIFGGIIA
LNRRVDLATAEKMHKLFLEIIMAPAFDDDAYEILAKKKNVRLLTINTADTPEELGTETTS
IYGGLLIQTRDDKAETPADMTVVTEVKPTEAQLKALAFAQTVVKHVKSNAIVVAQADQTL
GIGAGQMNRIGSVELALTQAQQNDNFAGAVMASDAFFPMDDCVDYAAKHDIKAIIQPGGS
IRDKDSIAKANEYGIAMVTTGVRHFRH
NT seq 1524 nt   +upstreamnt  +downstreamnt
gtgaagcgtgcattattaagtgtctctgataaaactggtttggtaccttttgcaaaaggt
ctggttgaacgcggttttgaactgatttcaaccggtggtacccatcgcgcactggctgaa
gctggggttgcggtgaccggcgtagaagcagtaaccggttttccagaaatgctcgatggt
cgagttaagacactgcatcctaagatccatgccggcatcttggcgcggcgggatgatcct
gcccatatgcaggcactagcagatcatgatattcagccaattgatgtggtttgtgtcaat
ctttatccgtttgccgcgaccattcagcgtgcgggtgtgacgcgtgccgaagcgattgaa
caaattgatattggtggcccgtctgcgttacgtgcggcagctaaaaatagtgacagtgtc
tgggccgtggttgatccagcagattatgcggatgttttagccggactcgatcaaaatgat
gctgatttgcggcaacggttggcagccaaagtcttctccgtcactgcagcttacgatgct
caaatcgcccattacttagatccagagccattcccagagcaattcacgccaacttatcac
aaacggcaggacttgcgttacggggaaaacagccatcaacaagctgccttttatgttgag
ccgaatcctgatccaactagtcttgccgctgctaagcaattacacggtaaagagctttct
tataacaatatcaaggatgcggatgcagcattggcaatgttgcgggaattcaaacaaccg
gcagccgtggccgttaaacatatgaacccatgcggcattggcttgggcgatacgcttgaa
gccgcttgggacaaggcatatgccgccgatccgatgtccatttttggcggcatcattgct
ttgaatcggcgggttgatcttgccactgccgagaaaatgcataaacttttccttgagatc
atcatggcaccggcatttgatgatgatgcctatgagattctggcgaagaagaaaaatgtg
cgcttattgacgattaatactgctgatacgccagaagaattgggaacagaaacgacttca
atttatggtgggttgttgattcaaacacgtgacgacaaagctgagacaccagccgatatg
acagtggtaacggaggtcaagccgactgaagctcaactcaaggcattggcatttgcgcag
acggtggtcaaacatgttaagagtaatgcgattgtcgtggcacaggctgatcagacgtta
gggattggcgccggtcaaatgaatcggattggctcggttgaattggcgttaacccaagcg
cagcaaaacgacaactttgccggtgcggtcatggccagcgatgcctttttcccgatggat
gattgcgtggattacgcggctaaacatgatattaaggcgattattcaaccgggtggcagc
attcgggataaggattcaattgcgaaggccaatgaatatggcattgcgatggtgacaaca
ggggttcggcatttccggcattaa

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