Lacticaseibacillus rhamnosus LOCK908: LOCK908_2618
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Entry
LOCK908_2618 CDS
T02731
Name
(GenBank) UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diaminopimelate-D-alanyl-D-alanine ligase
KO
K01929
UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase [EC:
6.3.2.10
]
Organism
lrc
Lacticaseibacillus rhamnosus LOCK908
Pathway
lrc00300
Lysine biosynthesis
lrc00550
Peptidoglycan biosynthesis
lrc01100
Metabolic pathways
lrc01502
Vancomycin resistance
Brite
KEGG Orthology (KO) [BR:
lrc00001
]
09100 Metabolism
09105 Amino acid metabolism
00300 Lysine biosynthesis
LOCK908_2618
09107 Glycan biosynthesis and metabolism
00550 Peptidoglycan biosynthesis
LOCK908_2618
09160 Human Diseases
09175 Drug resistance: antimicrobial
01502 Vancomycin resistance
LOCK908_2618
Enzymes [BR:
lrc01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.10 UDP-N-acetylmuramoyl-tripeptide---D-alanyl-D-alanine ligase
LOCK908_2618
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Motif
Pfam:
Mur_ligase_M
Mur_ligase_C
Mur_ligase
DUF7779
LpxD
Motif
Other DBs
NCBI-ProteinID:
AGP75225
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Position
complement(2603693..2605084)
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AA seq
463 aa
AA seq
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MMKMTLAEIARVVKAQPLSETVGSQVATGVAFDSRRLKPGMLFVPLHGERDGHEFIPAAA
AAGAVATFVAEDHLPMTTKLPTLVVPDPLAAMQKLAQYYLLMKVNPKVVAITGSNGKTTT
KDMTAAILATQYHVVKTPDNYNNEIGVPMTILSMEPNTEVLVLEMGMDRPGQLHALSSLA
EPDVAVITMIGEAHIEFFKTRAKIADAKMEITDGLKEDGTFIFNGDEPLLVSRAKQVTQS
QETFGLHPENTLFAHSISGHRNHTEFTVEQWPELTFSIPIMGEYNVVNALAALLVGRRFH
VKPEAMQKALAHFQVTANRTQWLIGDVGEQILSDVYNANPTAMKAVIHDFSEFQTAGRHI
AVLGDMLELGDQSRALHAGLADALDPHEIQEVYLYGSEMQALAEALTTKYPQDQVHYYPL
DAKSTMIRDLQNDVGHDDMVLLKASHGLHLETVLAALVAGGHA
NT seq
1392 nt
NT seq
+upstream
nt +downstream
nt
atgatgaaaatgacattggcagagatcgcacgtgtcgtaaaagcccagccactctctgaa
acagtcggttcgcaagtggcaaccggggtggcatttgattcgcggcgattgaagccggga
atgttatttgtcccattgcatggcgagcgtgacgggcacgagtttattccagcggcggct
gctgcgggggcagtcgcaacttttgtggcagaggaccatctgccaatgacgactaaactg
ccaacattggtggtcccggatccgctggcagccatgcagaagttagcccagtattatttg
ctaatgaaagtgaaccctaaagtcgttgccatcaccggcagcaatgggaagaccacgaca
aaagacatgactgcggcgattttggcaacgcaataccatgttgtgaagacgccggataat
tacaataatgaaatcggtgtcccaatgacgattctcagtatggagcccaataccgaagtg
ctggtgcttgagatggggatggatcggcccggccaattacatgcattgtcatcgttggcc
gaaccggatgtggcagtgattaccatgattggcgaggcccatattgaatttttcaagacg
cgcgctaagattgcagatgccaagatggaaattacggatggcttgaaagaggatggcacc
tttatttttaacggtgacgaaccgttattggtgagccgcgctaagcaagtcacccaatca
caagaaacatttggtttacatccggaaaatacgctttttgcccattcgattagcggccat
cgcaatcataccgaatttaccgtcgaacagtggccggaattgaccttttcaattcctatt
atgggtgaatacaatgtggtcaatgctttggctgcgttgctagtaggtcggcgtttccat
gtcaaaccggaagccatgcaaaaagcactggcgcattttcaggtgacggctaatcgcaca
caatggttaattggcgatgtcggcgagcagattctgagcgatgtttacaatgccaaccca
accgcgatgaaagcagtcatccatgattttagcgaatttcagacggcaggacgccacatt
gctgttttaggtgacatgcttgaacttggcgatcaaagccgggcgttgcatgcgggacta
gccgatgcacttgatccgcacgaaattcaggaggtttacttatacggttcggaaatgcag
gcacttgccgaagcgttaacgacaaagtatccgcaagatcaagtacactattacccgctg
gatgccaaaagtaccatgattcgcgatttgcaaaacgatgtcgggcacgatgacatggtg
ttgctaaaagcgagccatggtctgcatctggaaactgttttggctgcgctggtcgcaggc
ggacatgcgtga
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