Limosilactobacillus reuteri subsp. reuteri JCM 1112: LAR_0134
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Entry
LAR_0134 CDS
T00735
Name
(GenBank) phosphoribosylformylglycinamidine synthase II
KO
K23269
phosphoribosylformylglycinamidine synthase subunit PurL [EC:
6.3.5.3
]
Organism
lrf
Limosilactobacillus reuteri subsp. reuteri JCM 1112
Pathway
lrf00230
Purine metabolism
lrf01100
Metabolic pathways
lrf01110
Biosynthesis of secondary metabolites
Module
lrf_M00048
De novo purine biosynthesis, PRPP + glutamine => IMP
Brite
KEGG Orthology (KO) [BR:
lrf00001
]
09100 Metabolism
09104 Nucleotide metabolism
00230 Purine metabolism
LAR_0134
Enzymes [BR:
lrf01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.5 Carbon-nitrogen ligases with glutamine as amido-N-donor
6.3.5.3 phosphoribosylformylglycinamidine synthase
LAR_0134
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Motif
Pfam:
AIRS
AIRS_C
FGAR-AT_linker
HFX_2341_N
Motif
Other DBs
NCBI-ProteinID:
BAG24650
UniProt:
B2G5B8
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All DBs
Position
165102..167330
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AA seq
742 aa
AA seq
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MKQAMTPEEIKEKKPYLDWSLTEAEYDYIRTQLLGRLPNYTETGLFSAMWSEHCSYKKSK
PVLRLFPNKNERVLQGPGEGAGVVDIDDGQAVVFKAESHNHPTTVEPYQGAATGVGGILR
DIFSMGARPIASLDSLHFGELDNSTTRMKVTNTVRGIGDYGNCMGIPTIAGETTFDPCYQ
GNILCNAMSVGLMDQKDIQQGRAAGIGNAVMYVGAKTGRDGIHGATFASADFNDENMTQR
SAVQVGNPFMEKLLLEACLDLIRNHPDWLVGIQDMGAAGIVSSSAEMASEGQSGMELNLD
LVPQREPGMSAYEIMLSESQERMLLCVKKGHEEDVKKIFDFYDLEAVTIGRITAGHDYVL
FHDGEEVCHIPVSSLTDDVLEEESLEKKPARIELAEQQPAWIPDIDNVAEVLTALLAQST
IADKSSLYQQYDSQVRTNTVAGPGSDAGVLRIRGTHKGLAMTTDGNGRFVYLSPEVGGQI
ALVEAAANIIASGAEPLAITDCLNYGDPTDPEIFWELHQSVQGMADACREFNTPVISGNV
SLYNENNGQAIHPTPMVGMVGLIKNIDRVIPSFVQHPGDKVYLVGQTRDDYAGSELQKMM
TGDISGIVESFDLHHVHQYMQRLLTTMENGLVSSAHDLSEGGLGVALAETVFKTDLGLKI
DLADQHTARLFSETPGRFIVTVAPEKATEFEQVLGKDAHLIGEVTNSHWLMVKLANGELN
ENVAKLQETWEEAIPCQLKSKD
NT seq
2229 nt
NT seq
+upstream
nt +downstream
nt
atgaaacaagcaatgaccccagaagagattaaagaaaagaaaccatacttagattggagc
ttgactgaagcagaatatgattacattcgtacccagctcttaggacgattaccaaattat
actgaaactggcttgttttctgcgatgtggagtgagcactgttcatataaaaagtcaaaa
ccggttctgcgtctcttccctaataaaaatgagcgagtattgcaaggtcccggagaagga
gcaggggttgttgatattgatgatggacaagcagtggtattcaaagctgaaagtcacaat
catccgacaactgttgaaccttatcaaggagcggcaactggtgtcggtgggattctacgg
gacattttcagcatgggtgcacgaccaattgcttcccttgattccctccatttcggtgaa
ttagataattcgacaacgcggatgaaagtaactaataccgttcggggaattggtgattac
ggtaattgtatgggaattcctacaattgcgggtgaaacaacatttgatccatgctaccag
ggcaatattctgtgtaatgcaatgagtgtcggcttaatggaccagaaagatatccagcag
ggtcgcgctgccggaattggaaatgcagtgatgtatgtcggtgctaaaactggccgtgac
ggaattcatggcgccacctttgcttcagcagactttaatgatgaaaatatgacgcagcgt
tcggcggttcaagttggtaatccttttatggaaaaactcttattagaagcttgccttgat
cttattagaaatcatcctgactggttagtaggaattcaagatatgggggcagcaggaatt
gtttcttcaagtgcggaaatggcttccgaaggtcaaagtggaatggagctaaatttggat
cttgttccgcaacgtgaacccgggatgtcggcttatgaaattatgcttagtgaatcccaa
gaacgaatgcttctttgcgtaaaaaaaggccatgaagaagatgtcaaaaagatttttgat
ttttacgatcttgaagcggtcacaattggccggattactgcgggtcatgattatgttctc
tttcatgatggtgaagaagtatgtcatatcccagtgtcgagtttaacggatgacgtacta
gaagaagaaagcctagaaaaaaagcctgcgcggattgaattagccgaacagcagccagcg
tggattccggatattgataacgttgctgaagttttaactgccttgcttgctcagtcaacg
attgcggataaaagtagtctttatcagcaatatgattctcaagtacggacgaatacagtg
gctggtcccgggagtgatgctggggttctgcggattcgtggaacacataaagggttagcg
atgacaactgatgggaacggtcggtttgtttaccttagtccagaagttggtggacaaatt
gccttagttgaagcggctgccaacataattgccagtggagccgaaccgttagcaattact
gactgcttaaattatggtgacccaactgatccagaaattttctgggaacttcatcaatct
gtccaagggatggctgatgcttgccgtgaatttaataccccagttatttctgggaatgtt
tctttatataacgaaaacaatgggcaagcaattcacccgacgccgatggttggaatggtc
ggcctgattaaaaatattgatcgcgtaattccttcgtttgtccaacacccgggagataag
gtttacctagtgggccaaactcgtgatgattatgcggggtctgagttgcaaaaaatgatg
accggtgatattagcggaattgttgaatcatttgaccttcatcatgttcatcaatatatg
caacggttattgacaacgatggagaacggccttgtttccagtgcgcatgatttgagtgaa
ggtggcctcggagtagctttagcagaaacggtcttcaaaactgatttagggttgaaaatt
gaccttgctgatcagcacacagctcgcctgtttagtgagactcctggaagatttatcgtg
acggttgctcctgaaaaagcaaccgaattcgaacaggtattaggaaaagatgcgcactta
atcggagaagttacgaatagtcactggttaatggttaaactggcaaatggtgaactcaat
gaaaatgttgcgaaattacaagaaacatgggaggaggcaattccgtgccaactgaaatca
aaggattaa
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