Limosilactobacillus reuteri subsp. reuteri JCM 1112: LAR_0234
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Entry
LAR_0234 CDS
T00735
Name
(GenBank) UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diamino pimelate--D-alanyl-D-alanine ligase
KO
K01929
UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase [EC:
6.3.2.10
]
Organism
lrf
Limosilactobacillus reuteri subsp. reuteri JCM 1112
Pathway
lrf00300
Lysine biosynthesis
lrf00550
Peptidoglycan biosynthesis
lrf01100
Metabolic pathways
lrf01502
Vancomycin resistance
Brite
KEGG Orthology (KO) [BR:
lrf00001
]
09100 Metabolism
09105 Amino acid metabolism
00300 Lysine biosynthesis
LAR_0234
09107 Glycan biosynthesis and metabolism
00550 Peptidoglycan biosynthesis
LAR_0234
09160 Human Diseases
09175 Drug resistance: antimicrobial
01502 Vancomycin resistance
LAR_0234
Enzymes [BR:
lrf01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.10 UDP-N-acetylmuramoyl-tripeptide---D-alanyl-D-alanine ligase
LAR_0234
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Gene cluster
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Motif
Pfam:
Mur_ligase_M
Mur_ligase_C
MurT_C
Mur_ligase
DUF3323
Motif
Other DBs
NCBI-ProteinID:
BAG24750
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All DBs
Position
277758..279137
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AA seq
459 aa
AA seq
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MKMKLAEIAKAINAQNDIEQWKDVEVTSVSFDSRHLDQGSLFVPLQGAQDGHQYVPSAFT
NGAVASLWASDHEITDQTHPLLVVSDPLAALQQLGKYYLHKINPIVVAVTGSNGKTTTKD
MIASILSTQFNVAKTYANFNNEIGVPVTLLNMESNTEAVVVEMGMDRFGQLDFLSKLVNP
DIAVITMIGEAHIEFFGTRDKIADAKMEITHGLKEDGTLVFNGDEPLLEERVKDLAQRQM
RFGRQLSNNLYATSVHDEPRQLSFTVNEWPDEEFTIPMVGEYNINNALAAMEVGKILHIT
PAHMKQALANVELTENRAEWVKGKNGEQILSDVYNSNPTAAKEVLKTIAETPVAGRRIAV
LGDMLELGDAAAKLHASLAEEIDHQKIASVYLVGEQMKNLKDKLIQEGYPAEDIHHYAAS
DLQQLIADLTATLTGEDIVLLKASHGIHLEEVLTALKAE
NT seq
1380 nt
NT seq
+upstream
nt +downstream
nt
atgaaaatgaaattagcggaaattgccaaggcgatcaacgcacaaaatgacattgaacaa
tggaaagacgtagaagtgactagtgtgtcatttgacagtcgacacttagatcaagggagc
ttatttgttccattgcaaggtgcccaagacggccaccaatacgtaccgagtgcttttacc
aatggtgcagtagctagtttatgggctagtgaccatgagataacggatcagacgcacccg
ctattagtcgttagtgatccactagcggcccttcaacaactagggaagtactacttgcat
aagatcaatccgattgttgttgcagttacaggcagtaatgggaagacgacgactaaagat
atgattgcgtcaatcttaagtacgcagtttaatgtcgcgaagacatatgctaattttaat
aatgagattggggttccagtaacgcttcttaacatggagtctaataccgaagcagtggta
gttgagatgggcatggaccgttttggtcagcttgacttcttaagtaagcttgtaaatcct
gacattgccgttattacaatgattggggaagcacatatcgaattcttcgggactcgtgat
aagattgctgatgcaaagatggaaattacccatggcctaaaggaagatggaacactagta
tttaatggggatgaaccattattagaggaacgggtaaaagatcttgcccaacgacagatg
cgctttggtcggcaactaagcaataatttgtatgcaacaagtgtccacgatgaaccacgg
cagttatcatttaccgtcaacgaatggccagatgaagaattcactatcccaatggttggt
gaatacaatattaataatgcgttagcggctatggaagtgggtaagattctgcatattact
cccgcccacatgaagcaagcgttggcaaacgttgaattaacggaaaatcgtgctgaatgg
gttaaaggaaagaatggtgaacagatcttaagtgatgtttacaattcaaacccgaccgct
gccaaggaagtccttaagacgattgcagaaacaccagtagctggtcgccggatcgccgta
ttaggggacatgctggaattaggggatgctgcggcaaagttgcatgctagcttagcagaa
gagattgaccaccaaaagattgctagtgtttaccttgtaggcgaacaaatgaaaaatctt
aaagataagttgatccaagaagggtacccagctgaagatatccatcattatgctgctagt
gaccttcaacaattaattgccgatcttacggctactttgacaggtgaggatattgttcta
ttgaaagcaagtcatggcattcacctagaagaagtcttgacggcattaaaagcagaatag
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