Leminorella richardii: NCTC12151_02686
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Entry
NCTC12151_02686 CDS
T05503
Symbol
thrA
Name
(GenBank) Aspartokinase I/homoserine dehydrogenase I
KO
K12524
bifunctional aspartokinase / homoserine dehydrogenase 1 [EC:
2.7.2.4
1.1.1.3
]
Organism
lri
Leminorella richardii
Pathway
lri00260
Glycine, serine and threonine metabolism
lri00261
Monobactam biosynthesis
lri00270
Cysteine and methionine metabolism
lri00300
Lysine biosynthesis
lri01100
Metabolic pathways
lri01110
Biosynthesis of secondary metabolites
lri01120
Microbial metabolism in diverse environments
lri01230
Biosynthesis of amino acids
Module
lri_M00016
Lysine biosynthesis, succinyl-DAP pathway, aspartate => lysine
lri_M00017
Methionine biosynthesis, aspartate => homoserine => methionine
lri_M00018
Threonine biosynthesis, aspartate => homoserine => threonine
lri_M00526
Lysine biosynthesis, DAP dehydrogenase pathway, aspartate => lysine
Brite
KEGG Orthology (KO) [BR:
lri00001
]
09100 Metabolism
09105 Amino acid metabolism
00260 Glycine, serine and threonine metabolism
NCTC12151_02686 (thrA)
00270 Cysteine and methionine metabolism
NCTC12151_02686 (thrA)
00300 Lysine biosynthesis
NCTC12151_02686 (thrA)
09110 Biosynthesis of other secondary metabolites
00261 Monobactam biosynthesis
NCTC12151_02686 (thrA)
Enzymes [BR:
lri01000
]
1. Oxidoreductases
1.1 Acting on the CH-OH group of donors
1.1.1 With NAD+ or NADP+ as acceptor
1.1.1.3 homoserine dehydrogenase
NCTC12151_02686 (thrA)
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.2 Phosphotransferases with a carboxy group as acceptor
2.7.2.4 aspartate kinase
NCTC12151_02686 (thrA)
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Gene cluster
GFIT
Motif
Pfam:
Homoserine_dh
AA_kinase
ACT_9
NAD_binding_3
ACT_7
ACT
Motif
Other DBs
NCBI-ProteinID:
SQI42733
UniProt:
A0A2X4UV32
LinkDB
All DBs
Position
1:complement(2834175..2836634)
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AA seq
819 aa
AA seq
DB search
MRVLKFGGTSVANSERFVRVADIIENNARQGQVATVLSAPAKITNHLVAMIEKTVAGQDV
MTNMRDAEQIFSELLSGLEKIQPGFDAEGLRRLVEQEFAQLKHVLHGISLLGQCPDSVNA
SIISRGEKLSIAIMESVFKARGYGVTVINPVAMLLAHGHYLESTVDIAESSRRLVEMAIP
QDHIILMAGFTAGNEKGELVVLGRNGSDYSAAVLAACLRADSCEIWTDVDGVYTCDPRSV
PGARLLKSMSYQEAMELSYFGAKVLHPRTIAPIAQFQIPCLIKNTANPQAPGTLISRESG
DDRYPVKGITNLNNMAMINVSGPGMKGMVGMAARVFSVMSRAGISVVLITQSSSEYSISF
CIPQGELSRAKKALEDEFYLELKDGLLDTLDVVERLAIISVIGDNMRTLRGMSARFFTAL
ARANINIVAIAQGSSERSISAVVNNDSAITAVRASHQVLFETNQVLDVFVIGVGGVGGAL
LDQIQRQQPWLKQKNIDLRVCGIANSRGMVTSTLGVPLENWREALAAAEEPFNLGRLIRL
VKEFHLLNPVIVDCTSSEEVASQYADFLADGFHVVTPNKKANTGSMNYYHQLRQAASAGN
RKFMYDTNVGAGLPVIENLQNLLNAGDELLRFSGILSGSLSFIFGKLDEGLSLSEATRLA
KEKGYTEPDPRDDLSGMDVARKLLILAREAGYALELEDIKVDSVLPASFDASGDTAAFMQ
RLPQLDAEFAQRVQAAAKEGKVLRYVGAIEDGQCSVKIEAVDDNDPLFKVKNGENALAFY
TRYYQPLPLVLRGYGAGNDVTAAGVFADVLRTLSGKLGV
NT seq
2460 nt
NT seq
+upstream
nt +downstream
nt
atgcgagttctgaaatttggcggtacatcagtagcaaactccgaacgctttgtgcgcgtc
gcggatatcatcgagaacaacgcgcgtcagggccaagtggctaccgtgctttccgctccg
gcaaaaataaccaatcatctggtggcgatgattgaaaagaccgtcgccggtcaggacgtt
atgaccaacatgcgtgatgcagagcagattttttcagaattgctgagcggtttggaaaaa
atccagccgggatttgatgcagagggtcttcgtcgtcttgtggagcaggaattcgcgcag
ctcaagcacgtgctgcacggcatttctctgcttggccaatgcccggacagcgtaaatgct
tccatcatcagccgcggtgaaaagctgtctatcgccatcatggagtctgtctttaaggcg
cgcggttatggggtgacagtgatcaatccagtcgccatgctattggctcacggccactac
ttagaatcgactgtagatatcgcagagtccagccgccgcctagtggagatggcaattcct
caggatcacattatcctgatggccggctttactgccggtaacgagaagggggaattagtc
gttctggggcgcaacggctccgactattccgccgcggtgctggctgcctgcctgcgcgct
gacagctgtgaaatctggactgacgtcgacggcgtatacacctgtgacccgcgctctgtg
ccgggggcgaggctgttaaaatcgatgtcctatcaggaggctatggagctgtcttacttc
ggtgccaaagtccttcaccctcgcactatcgcccctatcgcccagttccaaattccctgt
ctgattaagaacaccgccaatcctcaggctcccggcacgctgattagccgtgaaagcggt
gacgatcgctatccggtcaagggcattaccaacctgaacaacatggcgatgattaacgtt
tccggtccgggcatgaagggcatggtcggcatggcggcgcgggtgttttctgtgatgtcc
cgcgctgggatttcagtggtgctgatcactcagtcttcatctgaatacagcatcagcttc
tgtattcctcagggtgagctgtcgcgcgctaagaaagcgctggaagatgagttctatctg
gagctgaaagacggcctgctggatacgctggacgtggttgagcggctggcaatcatttcc
gtcataggcgacaacatgcgcacgctgcgcggcatgtcagcgcgcttttttaccgcgttg
gctcgcgccaatatcaacattgtcgctatcgctcagggctcgtcagagcgctctatctcg
gctgtcgttaacaacgattcggcgatcactgcggtcagagcgagtcatcaggtgctgttt
gaaaccaatcaggtactggacgtgttcgttatcggtgtcggtggggttggcggcgcgctg
ctggaccaaattcagcgtcagcagccctggctgaagcagaaaaatatcgatctgagagtg
tgcggcatcgctaactcgcgcggcatggtcactagcactctgggggtgccgctagaaaac
tggcgcgaagcgctggcggcggcagaagagccgtttaatctggggaggctgatccgtctg
gtgaaagagttccacctgcttaatcccgtgattgttgactgtacgtcgagcgaagaagtg
gcttcccagtatgcagacttcctggccgacggcttccacgtggtgacgccgaacaagaaa
gccaacaccggctcgatgaactattatcatcagctacggcaggctgccagtgcaggcaac
cgcaagtttatgtacgatactaacgttggcgccgggctgccggttatcgagaacctgcaa
aacctgctgaacgccggggacgagctgctgcgcttttccggtatcctgtccggctcgctg
tcgtttatcttcggtaagcttgatgaagggttgagcctgtcagaggcgactcggctggcg
aaagagaagggctatactgagccggatccgcgcgacgatttgtccggtatggacgtggcg
cgcaagttgctgattttagctcgtgaggcgggctatgcgctggaactggaagatatcaag
gtagactctgtactgcctgcgtcctttgacgccagtggtgacaccgcagcgtttatgcag
cgactgccgcagctggacgcagaatttgcgcaacgcgttcaggctgctgccaaagagggc
aaagtgctgcgctatgtcggcgcgattgaggacggacagtgcagtgtgaaaattgaagcc
gtggacgataacgatccgctgtttaaagtgaagaacggtgaaaacgcgctggcgttttac
actcgctactatcagcctctgccgctggtgctgcgaggctacggtgcaggcaatgacgta
acggcagcgggcgtatttgctgacgttctgcgtaccctgtcaggaaaactgggagtttga
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