| Entry |
|
|---|
| Symbol |
LRP1
|
|---|
| Name |
(RefSeq) prolow-density lipoprotein receptor-related protein 1 isoform X1
|
|---|
| KO |
| K04550 | low-density lipoprotein receptor-related protein 1 (alpha-2-macroglobulin receptor) |
|
|---|
| Organism |
lrj Lethenteron reissneri (Far Eastern brook lamprey)
|
|---|
| Pathway |
|
|---|
| Brite |
KEGG Orthology (KO) [BR:lrj00001]
09140 Cellular Processes
09141 Transport and catabolism
04148 Efferocytosis
133344615 (LRP1)
09180 Brite Hierarchies
09182 Protein families: genetic information processing
04131 Membrane trafficking [BR:lrj04131]
133344615 (LRP1)
09183 Protein families: signaling and cellular processes
04090 CD molecules [BR:lrj04090]
133344615 (LRP1)
Membrane trafficking [BR:lrj04131]
Endocytosis
Clathrin-mediated endocytosis
Low-density lipoprotein receptor (LDLR) family proteins
133344615 (LRP1)
CD molecules [BR:lrj04090]
Proteins
133344615 (LRP1)
|
|---|
| SSDB |
|
|---|
| Motif |
|
|---|
| Other DBs |
|
|---|
| LinkDB |
|
|---|
| Position |
20:4440959..4749245
|
|---|
| AA seq |
4621 aa
MERRVSVRLLQLFTALHVIASATAAVGTLSPITDDEEGDDDEEDREEEEQGCLWNQFQCG
GGACVPRSWVCDWESDCSDGSDETSCPPKTCSPTQFVCKDGLTCISLGWRCDGEKDCPDG
SDESPEICQKPNEMKCQVNHYHCLGTELCIHMSKLCDGNNDCPDGYDEGTHCREFAENCT
VTLCRHKCAVTREGPACYCTVGHEVTPDEKGCKDFDECAVYGTCSQNCLNTDGSYSCSCV
EGYLLQPDSKSCKAKNDPVDRPAALLIANSQNIVATYLNGSIVPGLTPVATRQASAMDFS
YSEEMVCWVNVGDSPTESRLHCARMAGLKGFSGERVINISLNVHHVEQMAIDWLTGNFYF
MDDVDDRIFVCNKQGDTCVTLLDLELYNPKAIALDPTMGKLFFTDYGQIPKVERCDMDGG
NCSKLVDSKIVFPHGIALDLVSRLVYWADAYLDYIEVVDYEGRNRRTIIQGPSVEHLFGL
SVFENYLYATSIDNSNSPQNTTVIRVNRFNSTDYQVLTRVVKGGALHIYHRRRQPTVRSH
ACAPDQYGKPGGCSDICLLASSHKTRTCRCRSGFSLGSDGKSCKKPDHELFLLYGKGRPG
IIRGMDVTGRVQDEFMIPIENLVNPRAVDFHAETGYVYFADTTNFLVARQKIDGTERETI
LKTNINNVEGIAVDWMGYNLYWTDDGLKTINVARLEKASQARRTLIEGNMTHPRAIAVDP
VHGFMYWTDWEEDPKGTKRGKIEHAWMDGTHRSIFVSSKTVLWPNGLSLDIPNGILYWCD
AYFDQIERIKLDGTERKVVYDGQELSHPFGLTHHGHNIFWTEYRLGTVYRYDTISRNTTV
LRNERPPIFEIRTYDREQQKSGTNACHVNNGGCSILCLAIPDGRACACADDQLLDADNIT
CKPNPDYTPPPQCHPGEFACKNGRCIQERWRCDGDNDCLDNSDEAPEICHQHTCPSDRFK
CQNNRCIPLRWLCDGDNDCGNSEDESNTTCAARTCPPNQFSCASGHCIPMSWKCDLDDDC
GDRSDEPPSCAYPTCFPLTQFACNNGRCINMNWRCDADNDCADASDEIGCNHSCSISQFK
CNSGRCIPSHWTCDGDNDCGDFSDETNPNCTKLATRPPGGCHGDEFQCKADGQCIPLRWR
CDGDTDCIDTSDEKECDGVVRTCDPTLQFSCRDTGRCISKTWFCDGDNDCEDNSDEEGCE
TMLCKPPSHSCANDSSICLPPKKLCDGHSDCPDGSDEGMLCDQCQVNNGGCTHNCTVAPG
EGVVCSCPSGMQLGKDKKSCDFMDYCARHLRCSQRCEQEKSIVKCGCYDGWMLMPDGENC
QSLDPFVPFIIFSNRHEIRRIDLHKGDYNVLVPGLRNTIAIDFHLNQSSLYWTDVVEDKI
YHGKLSETGGLTSVEVVVQHGLATPEGLAVDWIAGNIYWVESNLDQIEVALLNGTMRSTL
VAGGIEHPRAIALDPRYGILFWTDWDSSFPRIEAISMSGTGRHVIHHEMGAGGWPNGLTV
DYLENRIMWIDARSDSIYSALYDGTELIEVLRGHEFLSHPFAVTLFGGEVYWTDWRTNTL
VRANKWTGQNVTVVQRTNTQPFDLHVFHPTRQPMANNPCGDNGGRGPCSHHCLINYNRTA
ACACPHLMKLQPDKRTCSEHWKFLLYARQMEIRGVDIDAPYYNFIISFTVPDIDNVTAVD
FHGAEQRIYWSDVRTQTIKRAFINGTNVETIVSADLANAHGLAVDWISGNLYWTSYDANK
KQINVARMDGSFKTAVLQGLDKPHGLALHPIKGKMYWTDGDTINVANMDGSEKAVLHNQQ
KGPVGLSIDYEESKLYWISSGNGTINRCELDGSGLEIVETMKSKLTKPSALAIMGEKLWW
ADQASEQLGTCSKRDGSNAVVLRNSTANVMHLRVYDRDLQKGTNPCSVNNGNCAQLCLPS
SETVRTCRCTAGYNLQADQRNCEAGIGAFLLYSVHEGIRGIPLDPADKTDALVPISGTSL
AVGIDFHAGNDTIYWVDMGLSSIHRAKRDQTWREDIITNGLGRVEGIAVDWIAGNIYWID
QGFDVIEVARLNGSFRYVVISQGLDKPRAIAVHPDKGYLFWTEWGQNPRIERSRLDGTER
TVLVNVSIAWPNGISVDYEEDKLYWCDARTDKIERIDLETGENREVVLSTSNMDMFSVSV
FGDYIYWSDRTHANGSIKRGSKENATDVVALRTGIGVQLKDVKVFNKERQKGTNVCARKN
GGCEQLCLYRGEGRRMCACAHGLLAEDGVSCRDYDGYLLYSERTILKSVHLFDELNLNAP
VRPFEDPEHMKNVIALAFDYGSGPRPTSGGVPYRRRRIFFSDIHFGNIQQLFNDGTGRRV
IVENVGSVEGLAYHRGWDTLYWTSYTTSTITRHTVDQARPGAFDRETVVTMSADDHPRAF
VMDECLNLMFWTNWNELSPSIMRSFLSGANVQVIVGSNIRTPNGLAIDHRAEKLYFSDAT
LDKIERCEYDGSHRYVILRSEPVHSFGLAVYGDFVFWTDWVRRAVLRANKFTGTDVKVLR
GEIPQQPMGMIALANDTNSCELSPCKVMNGGCEDLCHITEDGRFNCKCRGERVLVDGTRC
VARKNSCDLQTEFECNNGDCIRYHLTCDGVADCKDKSDEKPFYCTSRQCKNGYVNCLNGR
CMETAKLCNGVNDCGDNSDEIACNNSTCGADEFRCGDGSCIANVTRCNQVVDCDDISDET
GCGPMNCTHYHRLGVQASGYVSCNSTSLCVLPAWICDGANDCGDYADEKNCKKKSGSPGC
SPDYFNCPSGPCIPTAWKCDREPDCDDGADELNCDMLCAVDHFECDNGKCITKRWMCDGE
DDCGDRSDEKDAHCSAVTCGPDKFQCPNSRLCIPPLWVCDGDRDCPDGADESVTSSCLFR
NKCPPEEFQCANRRCILQRWVCDHDNDCGDNSDESPECDYPMCGPNQFRCANGRCLLKGS
WECDGDFDCHDRSDEAPINPHCSANNSKCNDSSSFPCANGRCVNESMLCNNQDDCEDGSD
ERNCNINECADRRISGCTQECTDLKIGYKCKCRAGFQLKDDGKTCVDRDECRTTYPCSQT
CLNSHGSFKCLCTDGYRQRVNDSTSCKAISDEEAILIFANRYYLRKVNLDGSNYTLLKQG
LNNAVALDFEWSEQWVYWTDVTTQGSMIRRMHMNGSDTQILHQSINSEDEHGVLHRTSLS
NPDGLAVDWIGGNLYWCDKGRDTIEVSKLNGLYRTVLLNNGLKEPRALAVDVRGGYLYWS
DWGEHPHIGRMGMDGSNRSVVIDTKITWPNGLSLDYVNNRIYWADAREDYIQFADMDGAN
RHTVVSEDIPHIFALSLFEDHVYWTDWETKTVNRAHKSTGADRTTLISTLHRPMDLHVYH
PFRQPDVPNHPCKVNNGGCSNLCLISPGGQYKCACPTNFYLASDGRTCLSNCTASQFVCK
NDKCIPFWWKCDTEDDCGDRSDEPADCPDFKCRPGQFQCKNGICTNPAFICDGDNDCGDG
SDEANCDVHVCLPSQFKCRTTHRCIPGIFRCNGQDNCGDGEDEKDCPEVTCAPNQFQCSS
TKRCIPRVWVCDRDNDCGDGSDEPANCTQMTCGQEEFRCKGTGRCIPSRWKCDGDDDCGD
TSDEPKEECEDRTCEPYQFRCKNNRCVPGRWQCDYDNDCGDNSDEEGCTPRPCSESEFSC
ANGRCIAGRWRCDGDHDCSDGSDEKDCSPRCDHDQFQCRNGHCIPQRWRCDADIDCIDGS
DEDNCAAIVRTCPHHEFQCNNTLCKPLSWKCDGEDDCGDNSDETPEMCLKFQCPPGRQFR
CRNNRVCFWAGRQCDGVDNCGDGSDEENCEKPSPKPRICNSSEFKCGGTERKCISTQLVC
NRFDDCGDGGSDEVACGGDQFVNECHRPLNPCGDDAICHDTLRGYYCECKPGFQRKATTS
ICEDVNECAQFGVCTQLCNNTKGSYKCNCSKNYIKGLHHSCKAEGSEQMVLYIADNNEIR
SLAPNNPNMAYEQAYQGDATVRIDAMDAHVKSNRIFWTNWHMGRISMLELYPAGEHRHRR
QASGTVVDLDISGLKMPRGVAVDWVADNLYWTDSGRDVIEVAQLRGRYRKTLVSGMIDEP
HAIVLDPIRGQMYWSDWGNNAKIEQASMDGTRRHNFVEKDLQWPTGLAIDFMNQRLYWAD
AKLSVIGSIRLDGTDRVVAVDSKQGLLHPFSIEIFEDYIYGVTYVNNRVFRIHKFGSGTV
VNITAGMSHATDIVVFHPLKQPEVINPCEQRKCEWLCLLNPNGATCSCPNGWALVNGTCL
EVPTPTSQPDGSTPGPCTLPCLNGGSCFLNERGLAKCKCQPRFSGERCELDQCKEYCQNG
GTCMASPSGMPTCRCPNRFTGAQCERKVCDGYCLNGGACSVNAGNQPVCRCTDAYKGDRC
QSTLCDSYCMNGGVCSFAKDGSPLCACHPRFLGTRCDTDRCGHCPGGQCELGPGAGDVRC
NCTGPACSRCLEFCYNGGLCFWDSVAGRPACQCQPGWEGSQCERNSPNRSTSPDEGKTLS
VVVPLVLLALIIVSVVAFFCYRRRVKGAKGFQHQRMTNGAMNVEIGNPTYNMFEGEAEDD
VGELLDADFTLDPDKPTNFTNPVYASLYLDGPSSRNSLGSTDEKKELLSKSPEEELAEAL
A |
|---|
| NT seq |
13866 nt +upstreamnt +downstreamnt
atggagaggagagtgtccgtgaggcttctccaactcttcacggcgctgcacgtgatagcc
tcggccacagcagcggttgggacattgagccccatcacagacgacgaggagggtgatgac
gatgaagaagacagggaggaggaggagcagggctgcctgtggaatcagttccagtgcggt
ggtggggcttgtgtgccacgcagctgggtgtgcgactgggaaagtgactgcagcgatggc
tccgatgagaccagctgccctcccaagacgtgcagcccgacgcagtttgtttgcaaggat
gggctgacgtgcatctccctgggctggcgctgcgatggggagaaggattgtcccgatggc
tcggatgaatcgccggagatctgtcagaagccgaatgagatgaagtgtcaggtcaatcac
taccactgccttggaaccgagctgtgcattcacatgagcaagctatgcgacgggaataat
gactgtccggatggctacgacgaaggaacgcactgccgagagtttgcagaaaactgcaca
gtgacactgtgtcgtcacaagtgtgcggtgacgagggaaggccccgcttgttactgcacc
gtcggtcacgaggttaccccggatgagaaaggctgcaaagactttgacgagtgtgccgtg
tatggcacgtgcagccagaattgcctaaacaccgacggctcttactcgtgcagctgcgtt
gaggggtacctcctgcagcccgacagcaagtcctgcaaggccaagaatgacccggtcgac
cggccagcggctctgctcatcgccaactcccagaatattgtggcaacgtacctgaacggc
agcatcgtgccgggcctaacacccgtggcgacgcggcaggcgagcgccatggacttcagc
tacagcgaggagatggtgtgctgggtcaacgtgggcgacagccccacggagagcaggctt
cactgcgcacgcatggcaggcttgaaaggcttctccggcgagcgtgtcatcaacatttct
ctcaacgttcaccatgttgagcagatggccattgactggctgacaggaaacttctacttc
atggatgatgtcgacgaccggattttcgtgtgcaacaagcagggggacacctgcgttact
cttctcgacttggagctgtacaatccgaaagccatcgccctggaccctaccatggggaaa
cttttctttaccgactacgggcagatcccaaaggtcgagcgctgtgacatggatggagga
aactgcagcaagctcgtggatagcaagattgtttttccgcatggcatcgcgcttgacctg
gtcagccggctggtttactgggcagacgcctacttggactacatcgaggtcgtggactac
gagggtcgtaacaggagaaccatcattcaggggccctccgtggagcacctgtttgggctg
agcgtcttcgagaactacctctacgccaccagcatcgacaacagcaactcgccgcagaac
accacagtcatccgggtcaaccgcttcaacagcaccgactaccaggtgttgacacgcgtg
gtcaagggcggcgccctgcacatctaccaccggcgtaggcaacccacagtacgcagccac
gcctgcgccccagaccagtacggaaagccgggcggctgctctgacatttgcctgctggcc
agcagtcacaagactcgaacgtgccgctgccgctcgggattcagcctgggcagcgacgga
aagtcctgcaagaagcccgaccacgagctcttcctcttgtatggcaagggccgcccgggc
atcatccgcggcatggatgtgacggggcgagtgcaggacgagttcatgatccccatcgag
aacctcgtgaaccctcgcgccgttgacttccacgccgagaccggatacgtctactttgcc
gacaccaccaatttcctcgtggcgcggcagaagattgacggcacagagcgggagactatc
cttaaaaccaacattaacaatgtggaaggcattgccgtggactggatgggctacaatctc
tactggaccgacgatggtctgaagaccatcaatgtagctcgtttggagaaggcctcgcag
gcacggagaacactcattgaggggaacatgactcatccacgggccatcgctgtcgatcct
gtgcacggattcatgtactggactgactgggaggaggaccctaagggcaccaagcgaggg
aaaattgagcacgcctggatggacggcacccaccgctctatcttcgtctcctccaagacg
gtgctgtggcccaatggcttgtcgctcgatatccccaatggcattctctactggtgtgac
gcctacttcgaccaaattgaacgcattaagctggatgggaccgaacgcaaggtggtctac
gatgggcaggagctgagccatccgtttggcctgacccaccatggccacaacatcttctgg
accgaataccgcctgggcaccgtgtaccgctacgacaccatcagccgcaacaccaccgta
ctgcgcaacgagcgaccgcccatcttcgaaatccgcacctatgaccgcgagcagcaaaaa
tccgggaccaacgcgtgccacgtcaacaacgggggctgcagcatcctctgccttgctatc
cccgacggacgcgcgtgtgcctgtgctgatgatcagctgttggacgccgacaacattacc
tgcaaaccgaacccagactacacgcctccaccccagtgccatcccggcgagtttgcctgc
aagaacggccgctgcattcaggagcgctggcggtgtgacggggacaatgactgcttggac
aatagcgacgaagcaccggagatttgccaccaacacacttgcccttctgaccgcttcaag
tgtcagaacaaccgctgcatcccactgcgctggctctgcgacggcgacaacgactgtggg
aacagcgaggatgaatccaacactacttgtgccgctcggacatgccctccaaaccagttc
tcctgtgccagtggtcactgcatccctatgtcctggaagtgtgacctggacgatgactgt
ggagatcgctcggacgagccaccttcctgtgcataccccacgtgcttcccgctcacgcag
tttgcttgcaacaacggccgctgcatcaacatgaactggcgctgcgacgcagacaacgac
tgcgcggacgcgagcgatgagattggctgcaaccactcgtgctcgatttcccagttcaag
tgcaacagcgggcgttgcatccccagccactggacctgcgacggggacaacgactgcggc
gacttcagcgatgaaaccaaccccaactgcaccaagctcgcgacccgaccaccgggtggc
tgccacggggacgagttccagtgcaaagcggacgggcagtgcattccacttcgctggcgc
tgcgatggtgacaccgactgcatcgacacgagcgacgagaaggagtgcgatggcgtcgtg
cgcacctgtgaccccacgttgcagttttcctgtcgggatacgggccgttgcatcagcaag
acgtggttctgcgatggtgacaatgactgcgaggacaactctgacgaggagggctgcgaa
accatgctgtgcaagccaccctcccattcctgcgccaacgattccagcatctgtctgcca
cccaagaagctgtgcgatggtcacagcgactgtcctgacggctctgacgaaggcatgctg
tgcgaccagtgccaggtgaacaatgggggctgcacgcacaactgcaccgtggcgccgggc
gaaggggtggtgtgctcgtgcccaagtggcatgcagctggggaaggacaagaagagctgc
gacttcatggactactgcgcccgtcacctccgctgcagccagcgctgcgaacaggagaag
agcatcgtcaagtgcggctgctatgacggctggatgctgatgcctgacggggagaattgc
cagagccttgaccctttcgtccctttcataatattctccaaccgccacgagatccggcgc
atcgacctgcacaagggcgattacaacgtcctggtgccgggtctccgcaacaccatcgcc
atcgacttccacctcaatcagagctccctctactggaccgacgttgtggaggacaagatc
taccacgggaagctctccgaaacgggaggcctgacgagcgtggaggtggtggtgcagcac
gggctggccacgccggagggactcgccgtggactggatcgcgggcaacatctactgggtt
gagagcaacctggaccagatcgaggtggcgctactcaacgggaccatgcgcagcaccctg
gtggcgggcggcatcgagcatccgcgcgccatcgcgcttgaccctcgatacgggattctc
ttctggactgactgggattcgtcgtttccccggattgaggccatctccatgagtggcaca
gggcggcacgtcatccaccatgagatgggagctggaggctggcccaacggcctcaccgta
gactacctggagaaccgcatcatgtggatagatgcccgctccgactccatctactctgcc
ctgtacgatggcacggagctcattgaggtgctgcggggccacgagtttctgtcgcacccc
ttcgccgtcaccctctttggaggagaggtgtactggaccgactggcgcaccaacacgctg
gtgcgtgcaaacaagtggacgggccaaaacgtgacggtggtgcagcgcaccaacacgcag
cccttcgacctgcacgtcttccatccaactcggcagccgatggccaacaatccatgtgga
gacaatgggggcagaggtccgtgctctcatcactgcctcatcaactacaaccgaacagct
gcctgtgcctgtccacacctcatgaagctacagcctgacaaacggacgtgctctgagcat
tggaagttccttctctacgcccggcagatggaaattcgcggagtggatatcgatgcccct
tactacaacttcatcatctcgtttactgtgcctgacattgacaatgtgactgctgttgat
ttccacggagcggagcagcgcatctattggtccgatgttcgcacgcagaccataaagcgt
gccttcatcaatggtaccaacgtagagaccatcgtttcagcagacttggcaaacgcacac
ggcttggctgtcgactggatatccgggaacctttactggaccagctacgacgcgaacaag
aagcagatcaatgtggctcgcatggacggctccttcaagacggctgtgttgcaagggctg
gacaagccccatgggctggcgctgcaccccataaaaggaaagatgtactggacagatggt
gacaccatcaatgtagctaacatggatggaagtgaaaaagctgttctccacaaccaacag
aaaggccctgttggattgtccattgactacgaggagagcaagttgtactggatcagctct
gggaacggcaccatcaaccgctgtgagctggacggctcggggctggaaattgtagaaacg
atgaaaagcaagctcaccaagccgtcggcactcgccatcatgggagagaagctctggtgg
gcagaccaggcctctgagcagcttgggacctgcagcaagcgcgatggctccaacgctgtc
gtcctgcgcaattccacagccaacgtgatgcacttgcgcgtgtacgaccgggacctgcag
aaaggcacgaacccgtgcagcgtgaacaacggaaactgtgcccagctgtgcctccccagc
tcggagacggtgcgcacctgccgctgcacggccggctacaacctgcaggctgaccagcgc
aactgcgaagcaggtatcggagccttcctgctgtactccgttcacgaaggcatccgtggc
atccccctggacccagccgataagaccgatgccttggtgccaatatccggcacctcgctc
gccgttggcattgattttcatgcaggaaacgatacaatctactgggtggacatgggatta
agcagcattcaccgtgcaaagcgagaccagacttggagagaggacatcatcaccaatggc
ctgggaagagtcgaaggaattgctgtggactggattgccggaaacatctactggattgac
cagggctttgacgtgattgaggtggccagattaaacggctccttccgctacgtggtcatc
tcgcaggggctggataagccccgggccatcgccgtgcacccagataaagggtacctcttc
tggactgagtggggccagaaccctcgcattgagcgatcccgtttggatggaacggagcgc
actgtcttggtcaatgtcagcatcgcgtggcccaatggcatctctgtcgattatgaggag
gacaagctgtactggtgcgatgcccgcacagacaagatcgagcgcattgacctggagacc
ggagagaatcgggaggtcgtgttgtccaccagcaacatggacatgttctccgtgtctgtc
ttcggagactacatctactggagtgatcggacccatgctaatggctccatcaagagaggc
agcaaggaaaatgccacagatgtggtggccctgagaacgggtattggcgtgcaactcaag
gatgtgaaagtcttcaacaaggagagacaaaagggcacaaacgtttgcgccaggaagaac
ggtggctgcgagcagctgtgcctgtaccgcggcgagggccggcggatgtgcgcgtgcgct
cacggcctcctggcggaggacggcgtctcgtgccgcgactacgacggctacctgctctac
tcggagcgaaccatcctcaagagtgtgcatctcttcgacgagctcaatctcaatgcgccg
gtgcggccctttgaagacccggagcacatgaagaacgtcatcgcgttggcctttgactac
ggctcaggaccacgccccacctcgggtggcgtcccttaccgccggcgcaggatctttttc
agcgacatccactttgggaacatccagcagctcttcaatgatggaactggccgacgagtc
atcgtggagaacgtgggctctgtggaggggctggcttaccaccggggctgggacactctc
tactggacgagctacaccacgtccaccatcacgcgccacacggtcgatcaggccagaccc
ggcgccttcgaccgagaaaccgtcgttaccatgtcagcagacgatcacccacgtgctttt
gtcatggacgaatgcctcaacctgatgttctggaccaactggaacgagctgagccccagc
atcatgcgctccttcctctcgggagccaacgtgcaggtgatcgtgggcagcaacatccgc
acgcccaatgggctggccatcgaccatcgagcagagaagctctacttctccgatgccacc
ctcgacaagatcgagcggtgcgagtacgacggctcccaccgatacgttatcctgcgctca
gagcccgtgcactccttcgggctggctgtgtacggagactttgtgttctggacggactgg
gtgcgacgcgctgtgctgcgtgccaacaagttcacgggcaccgacgtgaaagtgcttcgc
ggggagatccctcagcagcccatgggcatgatcgcgcttgccaacgacaccaacagctgc
gaactgtctccctgcaaagtaatgaatggaggctgcgaggacctgtgccacatcaccgag
gatggccggttcaactgcaagtgtcgcggagaacgagtgctggtggatggaacgcggtgc
gttgcgcggaagaactcctgcgacctgcagaccgagttcgagtgcaacaatggtgactgc
attcgctaccacctgacgtgtgatggcgttgctgactgcaaggacaagtcggacgagaag
cccttctattgcaccagccgtcagtgcaagaacggctacgtgaattgcctcaacggccgc
tgcatggagactgccaagctgtgcaatggtgtcaacgactgtggagataattcggatgag
attgcctgcaacaactccacctgtggcgcggatgagttccgatgcggcgacgggtcttgc
attgccaacgtcactcgctgcaaccaggtggtggactgcgacgatatctccgatgagacc
ggctgcggcccgatgaactgcacccattaccaccggctgggcgtgcaggcgtcgggctac
gtgagctgcaactccacgtcgctgtgcgtgcttcctgcttggatctgtgacggcgccaac
gattgcggagactacgcagatgaaaagaactgcaaaaagaagtcgggctcgcctggctgc
agcccggactacttcaactgccccagcggcccctgcatccccacggcctggaagtgcgac
cgcgagccggactgtgacgacggagcagacgagctcaactgtgatatgctctgcgctgtg
gatcattttgagtgtgacaacggaaaatgcattaccaagcgttggatgtgcgatggggaa
gatgactgtggagaccgctctgatgaaaaggacgcccactgcagtgcggtcacgtgtgga
cccgacaagttccagtgccccaactcgcgcttgtgcatcccaccgctctgggtgtgcgac
ggggatcgcgactgccctgacggcgccgacgagagcgtcaccagcagctgcctttttcga
aataagtgccctcccgaggagttccagtgcgccaacagacgctgcatcctgcagcgctgg
gtgtgcgaccacgacaacgactgtggggacaattctgacgagtctcccgaatgcgattac
cctatgtgtggacctaatcagttccgctgcgcaaatgggcgctgcctgctcaaaggcagt
tgggaatgcgacggagactttgactgccacgaccgatcggacgaggctcccatcaaccca
cactgcagtgctaacaacagcaagtgtaacgactcgtcctcgttcccgtgcgccaacggg
cggtgcgtgaacgagagcatgctgtgcaacaaccaggacgactgcgaggacggctctgat
gaaaggaactgcaacatcaatgagtgcgccgaccggcgcatcagcggctgcactcaggag
tgcaccgacctcaagattggctacaagtgcaagtgtcgtgctggatttcaacttaaggac
gatgggaagacgtgcgtcgacagggatgaatgccgaaccacatacccatgcagccagacc
tgtctcaacagccacggcagcttcaagtgcctctgcacggatggctataggcagcgggtt
aatgattccaccagctgcaaggccatttctgacgaggaagccattctcatatttgccaac
cgctactacttgcgaaaggttaacctggatggctcaaactacacgctactcaagcagggg
ctcaacaatgcagtggctctggattttgagtggagcgagcaatgggtttactggacggat
gtgaccacgcaaggaagtatgatccgacggatgcacatgaacggatccgacacacagata
ttgcatcagagtataaactctgaggacgaacatggggtcctgcaccgcaccagcctcagc
aacccagacggactcgcggtcgactggatcggtggcaatctctactggtgcgacaagggg
cgggacaccatcgaggtgtccaaactgaatgggctctatcgcaccgtgctgcttaataat
ggcctcaaggagccccgggccctcgctgtggatgtccgtggagggtacctgtactggtcg
gactggggtgagcacccgcacattggacgcatgggcatggacggcagcaaccgcagcgtg
gtcattgacaccaagatcacgtggcccaacgggctgtcgctggactacgtcaacaaccgc
atctactgggcggacgcgcgcgaggactacatccagtttgcggacatggacggagccaac
aggcacacagttgtgagcgaggacattccgcatatcttcgcgctgtccctcttcgaggac
cacgtctactggaccgactgggagacgaagacggtgaaccgagcgcacaagagcacgggc
gcagaccggacgacgctcatcagcacgctgcacaggcccatggacctgcatgtgtaccac
cccttccggcagcctgacgttcccaatcatccgtgcaaagtgaacaacggaggctgcagc
aacctgtgcctgatctcaccgggcggtcagtacaagtgtgcctgccccaccaatttctac
ctggccagtgatgggcgtacctgcctttcgaactgcactgcaagtcagttcgtgtgcaag
aatgacaagtgcatccccttctggtggaagtgcgacacggaggatgactgcggagaccgc
tcggatgagccagctgactgccctgattttaagtgccgtcctggccaattccagtgcaag
aacggcatctgcaccaatccagccttcatctgcgacggggacaatgactgcggggacggc
tctgatgaagccaactgtgatgttcacgtctgcctgccaagccaattcaagtgtcgcacc
acccatcgctgcatcccaggcatcttccgctgtaatggccaggataattgcggagacggc
gaggatgagaaggattgcccagaggtcacgtgcgcccctaaccagttccagtgttcgtcg
accaagcgatgcatcccgcgcgtgtgggtgtgcgaccgtgacaacgactgcggggatggc
tctgatgagcctgccaactgcacccagatgacgtgcggccaggaggagttccgctgcaag
ggcacaggacgctgcatcccgtcccggtggaagtgcgacggggacgacgattgcggcgac
acgtcggacgagcccaaggaggagtgcgaggacagaacctgtgagccgtaccagttccgc
tgcaagaacaaccgttgtgtgccggggcgctggcagtgtgactacgacaacgactgtgga
gacaactctgacgaggagggctgtactccgcggccgtgctctgagagcgagttctcgtgc
gcgaacggacgctgcatcgctggccgctggcgttgcgatggtgaccacgactgctccgat
ggctccgacgagaaggactgctctccccgttgcgaccacgatcaattccagtgccgtaat
ggccactgcatccctcagcgctggcgctgcgatgccgacatcgactgcatcgatggcagc
gacgaggataactgcgccgcaatcgtgcggacctgtcctcaccacgagttccagtgcaac
aacacactgtgcaagcctttgtcctggaaatgcgatggcgaggacgactgtggtgacaat
tcggatgagaccccggagatgtgcttgaagttccagtgtccaccaggaagacagtttcga
tgcaggaacaacagagtgtgcttctgggccggacggcaatgcgatggcgttgacaactgt
ggggacggttcggatgaagagaactgcgagaagccgagcccaaagccacgcatttgcaac
agcagtgagtttaagtgcggcggcacggagaggaagtgcatcagcactcagctcgtgtgc
aaccgttttgacgactgtggcgatggtggctccgatgaggtggcctgtggaggagaccaa
tttgtcaacgagtgccatcgtccattgaacccgtgcggcgatgatgcgatctgtcacgac
accttacgaggatactactgcgagtgtaaacctggcttccagcgcaaggccaccacctcc
atatgtgaagatgtgaatgagtgcgcacagtttggagtgtgcacacagctctgcaacaac
acgaaaggctcctacaagtgtaactgttccaagaactacatcaaggggctccatcacagc
tgcaaggcagaaggctcggagcagatggtgttgtacatcgccgacaacaacgagatccgc
agcctggcgccaaacaaccccaacatggcatacgagcaggcctaccagggagacgcgacc
gtccgcattgacgccatggacgcccacgtcaagtccaatcgcatcttctggaccaactgg
cacatgggccgcatctcaatgcttgagctgtacccggccggggagcacaggcaccgccgt
caggcgtccgggactgttgtcgacctcgacatctcgggcctaaagatgccacgcggagtg
gccgtggattgggtggccgacaacctgtactggaccgactctggccgcgacgtcatcgag
gtggcgcagcttcgcggccgctaccgcaagacgctcgtctctggcatgatcgacgagcca
cacgccatcgtgctcgaccccatccgcggccagatgtattggtcggactggggcaataat
gctaagattgagcaggcatccatggatggcacaaggcggcacaactttgtggagaaggac
ctgcagtggcctacgggcttggcaattgacttcatgaaccagcggttgtactgggctgat
gccaagctctcggtgattggcagcattcgtctggatggcactgaccgggtggtggctgtt
gacagcaagcaagggttattacatccgttcagcatcgaaatttttgaggattacatatac
ggcgtgacgtacgtaaacaaccgcgtgttccgcattcacaagttcggcagcggcacggtg
gtcaacatcaccgcaggaatgagccacgccactgatatcgtcgtcttccacccgctcaag
cagccggaagtgataaatccgtgtgagcagaggaagtgtgagtggctgtgtctgctcaac
cccaacggggcgacctgcagctgccccaatggctgggcacttgtgaacggcacatgcctg
gaagtaccaacacccacaagtcagccggacggatccaccccaggcccatgcaccctgcca
tgtctcaatgggggcagctgcttcttgaacgagcgtgggctcgccaagtgcaagtgtcaa
ccgcgcttctctggcgaacgctgcgagcttgaccagtgcaaggaatactgccagaatggg
ggcacctgcatggcgtctccatcgggaatgcccacctgccgttgccccaaccgcttcacg
ggggcgcagtgcgagcgcaaggtgtgcgacggctactgcctcaacggcggcgcctgcagt
gtcaacgctgggaaccagcccgtctgccgctgcactgatgcctacaagggagacagatgc
cagagcacgctgtgcgacagctactgcatgaacggtggcgtgtgctccttcgccaaggat
ggctcgccgctatgtgcctgccacccgcgcttcctgggcacgcgctgcgacaccgaccgc
tgtgggcactgtcccggagggcagtgcgagctgggtccaggggccggggatgtccggtgc
aactgcacaggaccagcctgcagcaggtgcctggagttctgctataacggaggtctgtgc
ttctgggactctgtcgcaggacgccctgcatgccaatgccagccaggctgggagggcagc
cagtgtgaacgaaattctccaaataggtccacgagcccggacgaaggaaaaacgctatca
gtggtggtgcccctggttctgctcgccctgattattgtcagtgtcgttgcgttcttctgc
tacaggagaagagtaaaaggagccaaagggttccagcaccagcgcatgacgaatggagcg
atgaatgtggagatcggtaatcctacctacaacatgtttgagggcgaagccgaggatgac
gttggtgaactgctcgatgctgactttaccctcgatcctgacaagccgacaaacttcaca
aacccggtttacgcttctctatacctggatgggcccagcagccgcaattcgctgggaagc
acggatgagaagaaggaattgctttccaagagtcccgaggaagagcttgcagaggccctg
gcatag |
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