Lethenteron reissneri (Far Eastern brook lamprey): 133360009
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Entry
133360009 CDS
T09663
Name
(RefSeq) glutamate--cysteine ligase catalytic subunit-like
KO
K11204
glutamate--cysteine ligase catalytic subunit [EC:
6.3.2.2
]
Organism
lrj
Lethenteron reissneri (Far Eastern brook lamprey)
Pathway
lrj00270
Cysteine and methionine metabolism
lrj00480
Glutathione metabolism
lrj01100
Metabolic pathways
lrj01240
Biosynthesis of cofactors
lrj04216
Ferroptosis
Module
lrj_M00118
Glutathione biosynthesis, glutamate => glutathione
Brite
KEGG Orthology (KO) [BR:
lrj00001
]
09100 Metabolism
09105 Amino acid metabolism
00270 Cysteine and methionine metabolism
133360009
09106 Metabolism of other amino acids
00480 Glutathione metabolism
133360009
09140 Cellular Processes
09143 Cell growth and death
04216 Ferroptosis
133360009
Enzymes [BR:
lrj01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.2 glutamate---cysteine ligase
133360009
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Motif
Pfam:
GCS
Motif
Other DBs
NCBI-GeneID:
133360009
NCBI-ProteinID:
XP_061434559
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Position
66:complement(1863480..1906530)
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AA seq
626 aa
AA seq
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MAPQMRGTTLRWSDTKLCAGFVRARGLQQLVRGLTQRGHGDHPLLWGDEVEYMLVSFDHT
ARRARVLFNAEELINDLRAMDEEANPGYPSRWHLEYCSYMLEGIPAQPYGSSMAELASVE
PSMRLRRRDMLARLRSNETICSLTTFPRLGCPGFSEPECVPQHRDGQSASLFLPDEAITC
HPRFSALTRNIRERRGEKVVVNVPIFRDRNTPSPFIDQIPHGDEEAAIAVTADHIYMDAT
GFGLGNCCLQVTLQARNIEEARHIYDQLAPLCPIMMALGAAAPFYRGLVSDVDCRWSIAS
AANDDRTRQERGLEPLTTSKWRIPKSRFDSIDSFLSPGGAQFNDLELPKDEDVHLQLLDA
GIDPLLAQHFAHLFIRDPLVLFCEKIHADDDENEAYHFECIQSTNWQTLRFKPPPPNTNI
GWRVEFRPMDVQLTDFENAAYVVFVVLLTRAILSYGLNFLVPLSKVDQNIRKAQKRNAVL
EEMFYFRKDIQAEVDAPPADDTESEDEVGILMSIDTIINGKVGVFQGLIPIVNSFLEDME
VDVETWCTISHYMELISKRASGELGTTAQRLRAFVSGHPDYAHDSVISERVNYDLMLRCD
ALSRSGPHRHGADPLHELSHGACQTG
NT seq
1881 nt
NT seq
+upstream
nt +downstream
nt
atggcgccgcaaatgagagggacgacgctgcgctggagcgacacgaagctgtgcgcgggg
ttcgtgcgcgcacgcggcctccagcagctcgtgcggggcctcacgcagcggggccacggg
gaccacccgctcctctggggtgatgaggtcgagtacatgctcgtctccttcgatcacacg
gcgcgcagggcccgtgtcttgttcaacgcagaggagctgatcaacgacttgagagccatg
gacgaggaggccaacccggggtacccatcgcggtggcacctggagtattgcagctacatg
ctggaggggatcccagcgcagccgtacggaagctccatggccgagctggccagcgtggag
ccgagcatgaggctgcggcggagggacatgctggctcggctgcgctcgaacgagacgata
tgctctctcaccaccttccccagactcggctgcccaggtttctctgagcccgagtgtgtg
ccccagcaccgagatggacaatccgcgtccctgttcttgccggacgaggctatcacctgc
cacccacgcttcagcgcgcttacgaggaacatccgtgaaaggcgaggagagaaggtcgtg
gtgaacgtaccgatcttcagggacagaaacactccgtccccattcatcgaccaaatcccg
cacggtgacgaggaggcggccatcgcggttacggctgaccacatttacatggacgcgacg
ggattcggcttgggaaactgctgcctgcaggttacactgcaggccagaaacatagaagaa
gcgcgacatatctacgaccagctggctcctctgtgtcccatcatgatggcccttggcgcc
gccgcccccttctaccgggggctcgtgtcggacgttgactgccgttggagcatcgcctcc
gcggcaaacgacgaccgcacgcgacaggaaagagggctcgagcccctgacaacgtccaag
tggcgaatccccaagtcgcggtttgactccatcgatagcttcctgtcgcccggcggagcg
cagttcaatgacctggaactgcccaaggacgaggacgtccacctgcagctcctggatgca
ggcatcgatccgctgctcgctcagcactttgctcacctcttcatccgcgaccccctcgtg
ctgttctgcgagaagatccacgccgacgacgatgagaacgaggcctaccactttgaatgc
atccagtccacaaactggcagacgttgcgcttcaagcctccgccgccgaacaccaacatc
gggtggcgcgtcgagttccggccgatggacgtgcagctcacggacttcgagaatgcggcg
tacgtggtgttcgtggtgctgctcacgcgcgccatcctctcctatggcctcaacttcctc
gtgccgctctccaaggtagatcagaacatcaggaaggcgcagaagaggaacgctgtgctg
gaggagatgttttatttcaggaaggacattcaggcagaggtggacgctcccccagcagat
gacaccgagtccgaggacgaagtggggatcctcatgagcattgacaccatcatcaatggc
aaggtgggggtgttccagggcctcatccccatagtcaacagcttcctggaagacatggag
gtggacgtggagacttggtgcacgatctcccactacatggagctcatcagcaagcgtgcg
tctggggagctaggaacgacggcccagcggcttcgcgccttcgtgagcggccaccctgac
tacgcacacgacagcgtcatctcggagcgcgtcaactatgacctgatgctgcgctgtgac
gccctgtcgcgttcggggccccaccgccatggcgcggaccccttgcacgagctcagccac
ggcgcttgccagaccggatag
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