Lacticaseibacillus rhamnosus Lc 705: LC705_00253
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Entry
LC705_00253 CDS
T00990
Symbol
iolA
Name
(GenBank) Methylmalonate-semialdehyde dehydrogenase
KO
K00140
malonate-semialdehyde dehydrogenase (acetylating) / methylmalonate-semialdehyde dehydrogenase [EC:
1.2.1.18
1.2.1.27
]
Organism
lrl
Lacticaseibacillus rhamnosus Lc 705
Pathway
lrl00280
Valine, leucine and isoleucine degradation
lrl00562
Inositol phosphate metabolism
lrl00640
Propanoate metabolism
lrl01100
Metabolic pathways
lrl01120
Microbial metabolism in diverse environments
lrl01200
Carbon metabolism
Brite
KEGG Orthology (KO) [BR:
lrl00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00640 Propanoate metabolism
LC705_00253 (iolA)
00562 Inositol phosphate metabolism
LC705_00253 (iolA)
09105 Amino acid metabolism
00280 Valine, leucine and isoleucine degradation
LC705_00253 (iolA)
09106 Metabolism of other amino acids
00410 beta-Alanine metabolism
LC705_00253 (iolA)
Enzymes [BR:
lrl01000
]
1. Oxidoreductases
1.2 Acting on the aldehyde or oxo group of donors
1.2.1 With NAD+ or NADP+ as acceptor
1.2.1.18 malonate-semialdehyde dehydrogenase (acetylating)
LC705_00253 (iolA)
1.2.1.27 methylmalonate-semialdehyde dehydrogenase (CoA-acylating)
LC705_00253 (iolA)
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Motif
Pfam:
Aldedh
DUF7266
Wtap
Motif
Other DBs
NCBI-ProteinID:
CAR89092
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Position
253900..255375
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AA seq
491 aa
AA seq
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MTTQQAVKTLKNFINGQWVDAKTDTFEDVYNPATGEVLARVPHSTSEDVADAVAAAKAAF
ETWKRVSIPKRAKILFKYQQLLVEHQEELGRIVTQENGKSLSEAIAEVGRGIENVEFAAG
VPTLMMGDSLSAVATDVEATNYRYPIGVVGGITPFNFPMMVPCWMFPMAVATGNTFVLKP
SEKTPLTSQRLVELFQEAGLPDGVLNIVNGAVDVVNGLLDHPDVKAISFVGSERVGEYVY
KRGSDHLKRVQALTGAKNHTIVLADADLDAAVKGIISSSFGSAGERCMATSVLVLEESIA
DKFMAKFTQAAKDIKIGNGLDKDVFLGPVIRQENQERTLNYIKTGVKEGAKLVLDGSAEA
EKRDGYFVGPTIFEDVKTDMTIWHDEMFAPVLSVMRAKDLPEAVAIANQSELANGACLFT
DSAASIRYFRENIDAGMLGINLGVPAPIAVFPFSGWKHSFFGTLHANGKDSVDFYTHKKV
VTARYDQHRFN
NT seq
1476 nt
NT seq
+upstream
nt +downstream
nt
atgacaacgcaacaagcagttaagaccttgaagaattttattaatggtcaatgggttgat
gctaagaccgatacttttgaagatgtttataatccggcgacgggagaggttttggcacgg
gtgccgcattcgactagcgaggatgtggcagatgcagttgcagcggccaaagcagcgttt
gaaacgtggaaacgggtgtcgattcctaaacgtgccaagattcttttcaaatatcaacag
ctgctggtggagcatcaagaagagttgggacgtattgtcacgcaggaaaatggtaaaagt
ctcagtgaagcgattgccgaagttgggcgcgggattgaaaatgttgagttcgcggcaggc
gtgccgactctgatgatgggggattcgctctcggcggttgcgactgatgttgaggccacg
aattatcgttatccaatcggtgttgttggcgggattaccccgtttaattttccgatgatg
gttccgtgttggatgttcccgatggcggttgcaacaggtaatacgtttgtgttgaaaccg
tcagaaaagacaccgcttaccagccagcgtctggttgagttattccaagaagctggtctg
cccgatggtgttttgaacatcgtcaacggggcggttgatgtcgtcaacggtctgttggat
catcccgatgtcaaggcaattagtttcgtgggatccgaacgggttggcgaatatgtttat
aagcgcggcagtgaccatttgaagcgcgttcaggcattaactggcgctaagaatcacacg
atcgttttagccgatgctgatctcgatgctgcagttaaaggcattatcagttcgtcattt
ggatccgccggcgaacgctgcatggcgacatcggttttggtactggaagaaagcatcgct
gacaagtttatggcgaaatttacgcaggcagctaaagacatcaaaatcggtaatggtctg
gataaagatgttttccttggaccagtgattcgtcaggagaatcaggaacggacgttgaac
tatatcaagaccggggttaaggaaggcgccaagctggtcttagacgggtcagcagaagcc
gagaagcgtgatggttatttcgttgggccaactatttttgaagatgtcaaaaccgacatg
accatttggcacgatgagatgtttgccccggtactgtccgtgatgcgtgcaaaagattta
ccggaagcggttgccattgccaatcagtccgagctagccaatggcgcttgcctgtttacg
gattcggccgcatctattcgctacttcagagaaaatattgatgcgggcatgctgggcatt
aacttgggcgttccggcaccgattgctgtcttcccattttctggctggaaacattcattc
tttggcaccttacacgctaacggcaaggatagtgtggacttctacacgcataagaaggtt
gtgacggcaagatatgaccagcatcgttttaattag
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