Labeo rohita (rohu): 127160574
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Entry
127160574 CDS
T09007
Symbol
tyk2
Name
(RefSeq) non-receptor tyrosine-protein kinase TYK2
KO
K11219
non-receptor tyrosine-protein kinase TYK2 [EC:
2.7.10.2
]
Organism
lroh
Labeo rohita (rohu)
Pathway
lroh04217
Necroptosis
lroh04620
Toll-like receptor signaling pathway
lroh04621
NOD-like receptor signaling pathway
lroh05168
Herpes simplex virus 1 infection
Brite
KEGG Orthology (KO) [BR:
lroh00001
]
09140 Cellular Processes
09143 Cell growth and death
04217 Necroptosis
127160574 (tyk2)
09150 Organismal Systems
09151 Immune system
04620 Toll-like receptor signaling pathway
127160574 (tyk2)
04621 NOD-like receptor signaling pathway
127160574 (tyk2)
09160 Human Diseases
09172 Infectious disease: viral
05168 Herpes simplex virus 1 infection
127160574 (tyk2)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
lroh01001
]
127160574 (tyk2)
Enzymes [BR:
lroh01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.10 Protein-tyrosine kinases
2.7.10.2 non-specific protein-tyrosine kinase
127160574 (tyk2)
Protein kinases [BR:
lroh01001
]
Non-receptor tyrosine kinases
JAK family [OT]
127160574 (tyk2)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
PK_Tyr_Ser-Thr
Pkinase
FERM_F2
FERM_F1
SH2_1
Jak1_Phl
Kinase-like
ABC1
Motif
Other DBs
NCBI-GeneID:
127160574
NCBI-ProteinID:
XP_050959173
LinkDB
All DBs
Position
3:complement(8167381..8197366)
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AA seq
1160 aa
AA seq
DB search
MSRRGRSKKSRAHTLTGQCEGPGVHVFLFWTKEGERCLSYKEGEVTVEDLTIDAAKAVGI
TPVCHALFALYDPASSCWYSPNHKFSSEDQSGLLLHFRMRFYFRNWHGLGEKEPVVTRYA
LRTGTGAEPVTAPLLEMTSLEYLFAQAKYDFVNDLTCLDALKGEEEISRFKNECLGMAVL
HLSYTALQSGSSLQDVAKQTSFLHCIPQSFSRHIARNNVLTRFRIRRVFTNFVKTFQQHT
VGMGKLGSQEVMYKYISTLERLAPNFGVETFPVFSLDLRPDGDGSGSYLIASRTQTPSET
VNSQPTYEIRVSGSTGIWWRKRSAQWGNDYIHNQDREPQSPDEQEVAWNTFCDFPEISLI
AIQGINVCISRQDNMSMDMRLCSSLQARSLVSLLDGYFRLTTDAHHYLCHEVAPPRVVLS
ETNDLHGPILDEFVLHKLKKEAEEGAFIVRWSVLDYHRIILASLSRTKDGENPTYKQFRI
TQKGSIFKLEGWDQEFSSIKELTNSLKTFVLKSGEDSFTLKKCCLPRLGELSNLLVMRKG
ANSSIKTLSETLNLSQLRFHQIKDKEITKEQHLGRGTRTNIYAGWLKVHGSLEDEDDESN
NNHRNVKGIRVVLKILDQSHKDIALAFFETASLMSQVSHCHLVFVHGVSVKGSENIMVEE
FVEFGPLDVFLHREKARVTPQWKFTVAKQLASALCYLETKRLVHGNVCGKNILVVKKGLE
EGTSPFVKLSDPGISLSALSRGERVERIPWIAPECIADGARIGSAADQWSFGATLLEICN
NGDLPISGSTLPEKERFYETQSRLAVPSSQELASFISMCLTYDPAARPSFRTILRELTEI
QIKNPDISSECESLPDRDPSIFYKRYLKKIRDLGEGHFGKVMLYVYDPGNDGTGEYVAVK
ALKQESGSSLHDSWMKEIEILKSLYHNNIVKYKGCCTELGGQIVQLIMEYLPLGSLREYL
PKHRLGIAQSLLFAQQICMGMDYLHSKRYIHRDLAARNVLVENEGVVKIGDFGLTKYIPE
GEIYYRVREDGDSPVFWYAIECLKESKFSFASDVWSFAVTLYEILTHCNHRQSPPSKFFE
MMGLVHGQMTVVKLISLLEKNERLPCPRDCPREVYLLMEQCWDFNPGQRPSFNSLAESLK
DIRRTYKQQPSVQLAQLNHR
NT seq
3483 nt
NT seq
+upstream
nt +downstream
nt
atgtctagacgaggacgttcaaaaaaatccagagctcacacgctcacaggacagtgtgag
ggtcctggggtccacgtgtttctgttctggaccaaagagggagagcgctgcctgtcttac
aaggagggtgaggtgaccgttgaagatctcaccatcgacgcagcaaaggctgtggggatc
actccagtctgtcatgccttgtttgctctgtatgaccctgcatcctcgtgttggtacagt
ccaaatcacaaatttagttcagaagaccagtctggccttttgctgcatttccgtatgcga
ttttacttccgtaattggcacggattaggggaaaaggaaccggtagtgacacgttatgca
ttacggactggaacaggggcagagccggtgacggctcctttgctggagatgacctccctg
gagtacctctttgctcaggcgaaatatgattttgtgaatgacttgacatgtttggatgcg
ttgaagggagaggaagagatcagtcgctttaagaatgaatgtctaggtatggctgtgctt
cacctctcttacacggcactgcagagtggctcttctctacaggatgtggccaagcagacc
agctttctccattgcatccctcaatccttttcccgacacattgcccggaacaacgtcctg
acaaggttccgtattcggcgtgttttcacgaactttgtgaaaactttccagcagcacaca
gtgggcatgggaaaactcggatcacaagaggtcatgtacaagtatatatccacgctggag
cgcctggcaccgaattttggcgtcgagaccttccctgtgttcagtcttgatctgagacct
gatggagacggcagtgggtcgtacctcattgcctctcgaacacaaactccctctgaaacc
gtgaacagtcaacctacatatgagatcagagtgtctggatccaccggcatatggtggagg
aagagatcagcacaatgggggaatgactatattcataatcaggacagagaaccacagtca
ccagatgaacaggaagtggcctggaataccttctgcgacttccctgagatctctcttatt
gccattcaaggcataaacgtctgtatcagtcgccaagacaacatgtcaatggacatgcgt
ttgtgctccagtcttcaagctcggtctctggtttcactgctggatggatatttccgcctc
acaactgacgcgcatcattatctttgtcacgaagtggcaccgcccagagtggttctcagt
gagaccaatgacctgcacggtcccatactggatgagtttgtgctccacaaactgaagaaa
gaagcagaggagggagcgtttattgtgcgctggagtgttttggattaccatcgcataatc
ctggcatctctgagtcggacaaaggatggagaaaatccaacatacaaacagttcagaatt
acacaaaagggctccattttcaagctggaaggctgggatcaagagttctccagcataaag
gagctcaccaacagcttaaagaccttcgtgctgaagtctggagaagacagcttcactttg
aagaaatgctgcctgcccaggctaggagagctatcaaatcttctcgtaatgagaaagggt
gcgaacagtagcattaaaacgctctcggaaaccctaaacctgagccaactgcggtttcat
caaattaaggacaaggaaattacaaaggagcagcacttgggacgaggcaccaggactaac
atttacgcgggctggctgaaggttcacggttcacttgaggacgaagacgatgagtctaat
aacaatcaccgcaacgtaaaaggcatccgggttgtcctcaaaattctggaccagagccac
aaggatatagcactagcattcttcgaaacggctagtctcatgagtcaggtgtcacactgt
catctggtctttgtgcatggagtttcagtcaagggatctgagaacattatggtggaggag
tttgtggagttcggcccattagatgtgttcctgcacagagagaaggcgcgtgtcactcct
cagtggaagtttactgtggccaaacaacttgccagtgctctttgctatcttgaaacaaag
cgtttggtccatggaaatgtctgcggcaagaatattctggtggtcaagaagggtttggag
gagggcacgtccccttttgtgaagctcagtgaccctggcatttctctgtcggctctgtct
cgtggagaacgcgtggaacgcatcccgtggatcgctccggagtgtatcgccgacggggcc
cgtataggaagcgctgccgaccagtggagcttcggagcgactctgctggaaatctgcaac
aacggagatcttcctatcagtggcagcacactgcctgagaaagagcgattctatgagacg
cagagtcgcctggcggtgccgtcttctcaagagctggcgagctttatcagcatgtgtctg
acatatgaccctgctgcacggccgtccttccggaccattctgagagagctaacagagatt
cagattaaaaatccagacatttcgtccgaatgtgagtcactccctgacagagaccccagc
atcttttacaaacgctacctaaagaagatcagggatctgggagagggacatttcggaaag
gtgatgctgtacgtctatgaccctggcaatgacggaacgggagaatatgtggcggtgaag
gccttgaaacaagagagtggaagtagcctccatgattcctggatgaaggagatcgaaata
ctcaaatcactttaccacaacaatatcgtcaaatacaaggggtgctgtactgaactgggt
ggacagattgttcagttaatcatggagtatcttccactgggaagcctcagagagtacctg
cctaaacatcggttgggaatcgctcaaagtctcctgtttgcacagcagatctgtatgggg
atggactatctgcactccaaacgctacatccacagggatttggctgcacggaatgttttg
gtggagaatgaaggtgtggttaagatcggtgacttcggcttgacaaagtacattcccgaa
ggagagatctactatcgtgttcgtgaggacggagacagccctgtgttctggtatgccata
gagtgcctgaaggagagcaagttttcctttgcctctgatgtttggtcctttgctgtgacc
ctctatgagattttgacacactgcaatcatcgtcaaagccccccttcgaaattctttgag
atgatgggattggtccatggtcagatgactgtagttaaacttatttcccttctggagaaa
aacgagagactgccgtgccctcgagactgcccgcgtgaggtttatttactgatggagcaa
tgctgggatttcaaccctgggcagcgtccatcgttcaattccctggctgagtctctgaag
gacatccggcgaacgtacaaacagcagccgtctgtgcaactcgcgcagctcaaccatcgc
tga
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