KEGG   Labeo rohita (rohu): 127182802
Entry
127182802         CDS       T09007                                 
Symbol
plcb4
Name
(RefSeq) 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-4 isoform X1
  KO
K05858  phosphatidylinositol phospholipase C, beta [EC:3.1.4.11]
Organism
lroh  Labeo rohita (rohu)
Pathway
lroh00562  Inositol phosphate metabolism
lroh01100  Metabolic pathways
lroh04020  Calcium signaling pathway
lroh04070  Phosphatidylinositol signaling system
lroh04081  Hormone signaling
lroh04082  Neuroactive ligand signaling
lroh04261  Adrenergic signaling in cardiomyocytes
lroh04270  Vascular smooth muscle contraction
lroh04310  Wnt signaling pathway
lroh04371  Apelin signaling pathway
lroh04540  Gap junction
lroh04621  NOD-like receptor signaling pathway
lroh04912  GnRH signaling pathway
lroh04916  Melanogenesis
Module
lroh_M00130  Inositol phosphate metabolism, PI=> PIP2 => Ins(1,4,5)P3 => Ins(1,3,4,5)P4
Brite
KEGG Orthology (KO) [BR:lroh00001]
 09100 Metabolism
  09101 Carbohydrate metabolism
   00562 Inositol phosphate metabolism
    127182802 (plcb4)
 09130 Environmental Information Processing
  09132 Signal transduction
   04310 Wnt signaling pathway
    127182802 (plcb4)
   04371 Apelin signaling pathway
    127182802 (plcb4)
   04020 Calcium signaling pathway
    127182802 (plcb4)
   04070 Phosphatidylinositol signaling system
    127182802 (plcb4)
  09133 Signaling molecules and interaction
   04082 Neuroactive ligand signaling
    127182802 (plcb4)
   04081 Hormone signaling
    127182802 (plcb4)
 09140 Cellular Processes
  09144 Cellular community - eukaryotes
   04540 Gap junction
    127182802 (plcb4)
 09150 Organismal Systems
  09151 Immune system
   04621 NOD-like receptor signaling pathway
    127182802 (plcb4)
  09152 Endocrine system
   04912 GnRH signaling pathway
    127182802 (plcb4)
   04916 Melanogenesis
    127182802 (plcb4)
  09153 Circulatory system
   04261 Adrenergic signaling in cardiomyocytes
    127182802 (plcb4)
   04270 Vascular smooth muscle contraction
    127182802 (plcb4)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   04131 Membrane trafficking [BR:lroh04131]
    127182802 (plcb4)
Enzymes [BR:lroh01000]
 3. Hydrolases
  3.1  Acting on ester bonds
   3.1.4  Phosphoric-diester hydrolases
    3.1.4.11  phosphoinositide phospholipase C
     127182802 (plcb4)
Membrane trafficking [BR:lroh04131]
 Exocytosis
  Calcium ion-dependent exocytosis
   Phospholipases
    127182802 (plcb4)
 Endocytosis
  Macropinocytosis
   Phospholipase C
    127182802 (plcb4)
SSDB
Motif
Pfam: PI-PLC-X PH_14 PI-PLC-Y PLCB1-4-like_EFh PLC-beta_C EF-hand_like C2 EF-hand_7 EF-hand_6 EF-hand_PLCG2
Other DBs
NCBI-GeneID: 127182802
NCBI-ProteinID: XP_050994363
LinkDB
Position
20:complement(33746428..33800330)
AA seq 1248 aa
MTKSYEFNWQKHVPDFLQEGAVFDRFDEDPFVFEPSCHFKVDEFGFFLTWKSDGKEGQLL
ECSLINSIRPGVVPKDPKILASLEAAGKSEADLDGRIICICSGPDLVNLSFMYMVTDNTE
TAKKWMEGLRSVIHNFKANNVCPMTCLKKHWMRLSFLTNVNGKIPVRGITRTFGSGKTEK
GIFQALKELGLPSGKNDEIEHSAFTFDIFYALTQKICPRTDIEELFKKINGDKSDYLTVE
QLVSFLNENQRDPRLNEILFPFYDAKRVMQIIEKYERDADLKKKGRMSCDGFCRYLMSDE
NAPVFLDRLDLCQEMEHPLAHYFISSSHNTYLTGRQFGGKSSVEMYRQVLLSGCRCVELD
CWDGKGEDQEPIITHGKAMCTDILFKDVIQAIKETAFVTSEYPVILSFENHCSKPQQYKM
AKYCEEIFGDLLLKQPLEGFPVRDILFPRTQIQTRPALVSVENIESGQPLPSPNDLKRKI
LIKNKRLKPEVEQKQLESFKKHMEAGEMSIQAGEDENDEDLDSALDGKELNSDMKTSNTL
SLSEDPSDPDAQDSSLRKKIPDDDVTEISEATEITDATDVSEASDLENKKKGVETAEDAD
AEQQLIASYKYEGATTNIHPYLSAMVNYAQPVKFQGFEVAEERNIHHNMSSFNESVGLGY
LKTNAIEFVNYNKRQMSRIYPKGGRVDSSNYMPQIFWNAGCQMVSLNFQTPDLGMQLNQG
KFEYNGACGYLLKPDFMRRADRMFDPFSETPVDGVIAATCSVQVFSGQFLSDKKIGTYVE
VDMYGLPTDTIRKEFRTRMVMNNGLNPYYNEEPFVFRKVILPDLAVLRIAVYDDNNKLIG
QRILPLDGLQAGYRHISLRNEGNKPLSLPTVFCNIVLKTYVPDGFGAIVDALSDPKKFLT
IAEKRADQMRALGIETSDIADVPNENCKSDKKGKVSQVKTNVTPQSSSEVNATQNNISES
KRDNSAIVNQVNIEDLKQMKTFIKLMKKQQKELNTLKKRHAKEHNAMQKSHCTQVDKMVA
QHDKEKFTLEKLLEKAIKKRGENNCSDLKKETAIKVETLTTDHKEKVKDMVAQHTKEWSE
MINCHSTEEQEMKDAHVTQQCELLRKLLASVQEQQTLQLKLIHERQSKEMKANQAKTSME
NSKAISQDKSIKNKAERERRVRELNCSNTKKFLEERKRLAMKQAKELEQLQKSQREQLEK
LEKFNEQLLKSHHANSQTQGQRHAEDGEAGGGHGPQTSHGGVGAPSVN
NT seq 3747 nt   +upstreamnt  +downstreamnt
atgaccaaatcatacgagttcaactggcagaaacacgttcctgatttcctgcaggaagga
gccgtgtttgaccgattcgatgaggatcccttcgtctttgagcccagctgccatttcaaa
gtggacgagtttggcttctttctcacatggaagagtgacggaaaggaaggtcaacttctg
gaatgttctctgatcaacagcatccgtccaggagtcgtgccgaaggacccgaagatcctg
gcgtctctggaagcggcggggaagagcgaggcggatctggacggtcgcatcatctgcatc
tgcagcggaccggacctggtcaacctcagcttcatgtacatggtgacggacaacacggaa
acggccaagaaatggatggaaggcctaagatctgtgattcacaatttcaaggcgaataac
gtgtgtccaatgacgtgcctgaagaaacactggatgagactgtccttcctaacgaatgtc
aacggcaaaatcccggtccgaggcataacacggacgttcggctcgggtaaaacggagaaa
ggaatcttccaggcgctgaaggagctcggtctccccagtgggaagaatgacgaaatcgag
cattcggccttcacgttcgacatcttctacgctctgacgcagaaaatctgccctcgcacg
gacatcgaggagctcttcaagaagatcaacggcgacaaaagtgattatttaaccgtagag
cagttagtcagctttctgaatgaaaaccagcgggaccctcgactcaacgagatcctcttt
cccttctacgatgccaaacgagtcatgcagatcatcgagaagtacgagagagacgccgac
ttaaaaaagaaaggtcgcatgtcctgcgacggcttctgccgctatctgatgtcggatgag
aacgcgccggtgtttctggaccgtctggatctgtgtcaggagatggagcatccgctggct
cattacttcatcagctcgtcacataacacttacctgacgggccggcagttcggcgggaag
tcttcagtggagatgtaccgacaggtgctgctgtccggatgcaggtgtgtggagctggac
tgctgggatggtaaaggtgaggatcaggagcccatcattactcatgggaaggccatgtgc
accgacatcctgttcaaggatgtaattcaagccataaaggaaacggcgtttgtaacgtct
gaatatcccgttattctgtcgtttgagaaccactgcagtaagccgcagcagtataagatg
gccaagtattgcgaggagatctttggagacctgttgctgaagcagccgctggagggattc
ccagtacgtgacatcctatttccccgcacacaaatccagaccagacctgctttagtctcc
gtggaaaatattgaatccgggcagccgctgccgtcgcccaacgacctcaaacgcaaaata
ctcatcaaaaacaagcgcttaaaacctgaagtggagcagaagcagctggagtcctttaag
aagcacatggaggctggagagatgagcatacaggctggagaagatgagaatgatgaagat
ctggacagtgcgctggacggtaaagagctgaactcagacatgaagaccagcaacactctg
tctctgtcggaggatcccagcgatccggacgcgcaggacagcagcctcaggaagaagatc
ccagatgacgacgtcaccgagatctcagaagcgactgaaatcacggacgccaccgacgtg
tctgaagcgtcagacctcgaaaacaagaagaagggcgtggaaacggctgaagatgccgac
gccgaacagcagctcatcgcctcgtataagtatgaaggagccacgaccaacatccacccg
tacctgtcggccatggtcaactacgctcagcccgtcaagttccagggcttcgaggtcgcc
gaggagaggaacatccatcacaacatgtcgtccttcaacgagtctgtgggtttgggctat
ctgaagacgaacgccattgagtttgtgaactacaacaagcggcagatgagccgcatctac
cccaaaggaggccgcgtggactccagcaattacatgcctcagatcttctggaacgccggc
tgccagatggtgtctctgaacttccagactccagatctgggcatgcagctgaaccagggg
aagttcgagtacaacggcgcatgcgggtacctcctgaaaccagacttcatgcgccgcgca
gacaggatgttcgacccgttctctgagacgccagtagatggagtgatagcagcgacctgc
agcgtacaggtgttctcgggtcagttcttatcggataagaagatcggcacgtacgtggag
gtggacatgtacggccttcccaccgacaccatccggaaagagttccgcacgcgtatggtg
atgaacaacggcctgaacccgtactacaacgaggagccgtttgtcttcaggaaggtgatc
ctgccggatttggcggtgttgcgtatcgccgtgtacgacgacaacaataagctgatcggt
cagaggatcctgccgctggacgggctgcaggcgggttaccggcacatatcgctgcgcaac
gagggcaacaagccgctgtcgctgcccaccgtcttctgcaacatcgtcctgaagacatac
gtgcccgacggcttcggcgccatcgttgatgctctttccgatccaaagaagttcctcacc
atcgcagaaaaacgcgccgatcagatgcgagcactcgggatcgaaacgagcgacatcgca
gacgtgcccaacgaaaactgcaagagtgataagaagggaaaagtgagtcaagtgaagacc
aacgtgacgccacagagcagctctgaggtgaacgccacacaaaacaacatcagcgagagc
aaacgcgataattctgccatcgtgaatcaggtgaacatcgaagatttgaagcagatgaag
accttcattaaactgatgaagaagcagcagaaggaactgaacacgctaaagaaacgacac
gctaaggaacacaacgccatgcagaaatcgcactgcacgcaggtggacaaaatggtggct
cagcatgacaaggagaagttcacgctggagaagctgctggagaaggccatcaagaagaga
ggagaaaacaactgctccgacttaaagaaggaaacggccataaaggtcgagacgctcacc
acagaccataaagaaaaggtgaaggacatggtggcgcagcacactaaagaatggtcagag
atgatcaactgtcacagcacagaggaacaggaaatgaaggacgcccatgtgacgcagcag
tgtgagctcctcagaaagctgctggccagcgttcaggagcagcagacgctgcagctcaag
ctcatccacgaacggcaaagcaaagagatgaaggccaaccaggcgaagacgtcgatggag
aacagcaaagccatcagccaggacaagagcatcaaaaacaaggcggaacgcgagaggaga
gttcgggagctgaactgcagcaacaccaaaaagttcctggaggagagaaagaggctggcc
atgaagcaggcgaaagagctggagcagctgcagaaatctcaacgagagcagctggagaaa
ctcgagaagttcaacgagcagcttttgaaatcacatcatgcaaacagtcagactcaaggc
caaagacatgcagaagatggtgaagctggaggaggacatggaccgcagaccagccacggt
ggtgtaggcgctccatccgtcaactga

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