Limosilactobacillus reuteri I5007: LRI_1910
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Entry
LRI_1910 CDS
T02701
Name
(GenBank) glutamate-cysteine ligase/gamma-glutamylcysteine synthetase
KO
K01919
glutamate--cysteine ligase [EC:
6.3.2.2
]
Organism
lrt
Limosilactobacillus reuteri I5007
Pathway
lrt00270
Cysteine and methionine metabolism
lrt00480
Glutathione metabolism
lrt01100
Metabolic pathways
lrt01240
Biosynthesis of cofactors
Brite
KEGG Orthology (KO) [BR:
lrt00001
]
09100 Metabolism
09105 Amino acid metabolism
00270 Cysteine and methionine metabolism
LRI_1910
09106 Metabolism of other amino acids
00480 Glutathione metabolism
LRI_1910
Enzymes [BR:
lrt01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.2 glutamate---cysteine ligase
LRI_1910
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Gene cluster
GFIT
Motif
Pfam:
Glu_cys_ligase
ATP-grasp_6
RimK
Dala_Dala_lig_C
ATP-grasp_3
ATPgrasp_ST
GARS_A
R2K_2
ATP-grasp
ATP-grasp_4
Motif
Other DBs
NCBI-ProteinID:
AGO00120
UniProt:
R9WJ08
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Position
pLRI01:17979..20321
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AA seq
780 aa
AA seq
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MYRGIEEKIMNIRNIIKDNELQSLFTEGNFGIEKEGLRTDPSDQLAMTDHPHVLGSRLYH
PYLLTDFSEAQPETVTPVQPSLKLTFNWLEALHDVLHRSMNPDEYLWPNSMPNLLPDEED
IPIVRYNDPDAISYRQHLADSYGKKKQTISGIHFNFSFSEDFIEAIFQNQTTHQTKTELQ
NELYTKLSGNFLKYEWLLLYLFGASPYADSGFYDSKSGRLLKKPTDYVRSLRNSSFGYHN
HDEVIVDYDSAESYVRDIENFVETGHLSEEREFYGNARLRGKGDSLREMLESGVQYVEFR
SFDLNPLDRLGISYEQGRFYHLFFLYMVWVENKATREEILQGQEKMLNTADENPYQVSAY
QKEGLKILAGMLDMVNDLSLNDEFEELIKKAQEKFHHPEETLSARVADKIEKQGYLAFNR
QLGLKFKEYSTERPYVLNGFADMELSTQLLMYDAIELGVEVKVVDRADHFLKLSHENVVE
YVRNGNMTSKDTTISHFIMENKTVTKKILAEAGYHVPGGGEYHSIKEALKHYANYQNQPI
VVKPKSTNYGIGISVFKKFPDKASYKEALEIAFQEDDTVLVEEYVAGTEYRFFVLDDEVG
AVLLRVPANVIGDGESTIDELIDQKNDDPLRGADHRAPMAYIEKGAIETLMLKEQNLSFE
SIPEKGQTVYLRENSNISTGGDSIDFTNEMDESYNAIAVGIAKALEVKVTGIDLIIPDYK
TPSTEENPGYSCIEANFNPAMNMHAYVTKGKGRRLTKGILKMLFPDLVQQQKQQLQQTNK
NT seq
2343 nt
NT seq
+upstream
nt +downstream
nt
atgtatagaggaattgaggaaaagataatgaatataagaaacatcataaaagataatgaa
cttcaatctttgtttacagaaggaaattttggaatagaaaaagaaggattacgaacagat
ccttctgaccaattagccatgaccgatcatccccatgttttagggagtcgtttatatcac
ccttatttattaaccgattttagtgaagctcaaccagaaaccgtaactcccgttcaaccg
tcattaaaattaacatttaattggttagaagctttacatgatgtgctccaccggtctatg
aatcccgatgaatatctatggccaaacagtatgccaaaccttctccctgatgaagaggac
attccaattgttcgctataatgatccggatgctatttcttatcgacaacatcttgcggat
agctatggcaagaaaaaacaaaccattagtggaattcattttaatttttcatttagtgaa
gattttattgaagcaatttttcaaaatcagacaacccatcaaacaaaaacagaacttcaa
aatgaactttacacgaaattatccggtaactttttaaaatatgaatggctattattatat
ttatttggagcaagcccttatgctgattcaggcttttatgattcaaaatccggacgttta
cttaaaaagcctacagattatgtacgtagtttacgaaatagttcttttggttaccacaat
catgatgaagtcattgtggattatgattcagcagaaagctatgttcgagatattgagaac
tttgtagagaccgggcatttgtccgaagagcgagaattttatggaaatgcacgtctccga
ggaaaaggggactctttacgagaaatgcttgaatcaggcgttcaatatgttgaatttcgt
tcatttgatttgaatcctctggatcgattaggtatttcctatgagcaaggacgcttttat
catttattctttttatatatggtctgggtagaaaataaagcgaccagagaagagatatta
caaggtcaagaaaaaatgttaaatacagcagatgaaaatccttaccaagtatcggcgtat
caaaaggaaggtttgaagatcttggcaggaatgctggatatggtaaatgacctctcttta
aatgatgaattcgaagagcttataaaaaaagcccaagaaaaattccatcatcccgaagaa
acactaagtgctcgtgtagccgataagattgaaaaacaaggatatttagcctttaaccgc
caactaggcttgaagtttaaagaatattcaactgaacgtccttatgttttaaatggattt
gcagatatggaattatcgactcaattattaatgtatgatgccattgaattaggagttgag
gtgaaagttgttgatcgcgcggatcatttcttaaaactgtctcatgaaaatgttgttgaa
tatgtaagaaatggaaatatgacaagtaaagacactacaatttcgcattttatcatggaa
aataaaacagttacgaaaaaaatcttagcagaagctggatatcatgtaccaggtggtggc
gaataccattcaataaaagaagccctgaaacattatgcaaattatcagaatcaaccgatt
gttgtaaaacccaaatcaacgaattatgggattggcatttcagtctttaaaaaatttcct
gataaggcttcttataaagaggcgctcgaaatcgcgtttcaagaagatgacacggtcctt
gttgaagagtatgtggcgggaacggaatatcgtttctttgttttagatgatgaagtaggg
gcggtattgttgcgtgtgccagcaaatgttataggggatggcgaatcgacaattgatgag
ctaattgaccaaaaaaatgatgatccactaagaggagccgaccatcgagcacccatggct
tatattgaaaaaggtgctattgaaacattgatgttaaaagaacaaaatctgtcctttgaa
tctatcccagaaaaaggccaaacggtatatttacgagagaattcaaatatttctacgggg
ggcgattcaattgattttacaaatgagatggatgagagttataatgctatagctgtaggg
attgcgaaagcattagaagtaaaggtgaccgggattgatttgattattccggattacaaa
accccaagtactgaagaaaatcccggatattcttgtatagaagcaaactttaatccagca
atgaatatgcatgcttatgtaacaaaagggaaaggccgccgtttaacgaaggggatcttg
aaaatgcttttcccagatttagtccaacaacaaaaacaacaattacaacaaacaaataag
taa
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