Limosilactobacillus reuteri SD2112: HMPREF0538_20899
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Entry
HMPREF0538_20899 CDS
T01551
Symbol
cobA
Name
(GenBank) uroporphyrinogen-III C-methyltransferase
KO
K13542
uroporphyrinogen III methyltransferase / synthase [EC:
2.1.1.107
4.2.1.75
]
Organism
lru
Limosilactobacillus reuteri SD2112
Pathway
lru00860
Porphyrin metabolism
lru01100
Metabolic pathways
lru01110
Biosynthesis of secondary metabolites
lru01120
Microbial metabolism in diverse environments
lru01240
Biosynthesis of cofactors
Module
lru_M00924
Cobalamin biosynthesis, anaerobic, uroporphyrinogen III => sirohydrochlorin => cobyrinate a,c-diamide
Brite
KEGG Orthology (KO) [BR:
lru00001
]
09100 Metabolism
09108 Metabolism of cofactors and vitamins
00860 Porphyrin metabolism
HMPREF0538_20899 (cobA)
Enzymes [BR:
lru01000
]
2. Transferases
2.1 Transferring one-carbon groups
2.1.1 Methyltransferases
2.1.1.107 uroporphyrinogen-III C-methyltransferase
HMPREF0538_20899 (cobA)
4. Lyases
4.2 Carbon-oxygen lyases
4.2.1 Hydro-lyases
4.2.1.75 uroporphyrinogen-III synthase
HMPREF0538_20899 (cobA)
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Paralog
Gene cluster
GFIT
Motif
Pfam:
TP_methylase
HEM4
Motif
Other DBs
NCBI-ProteinID:
AEI57110
UniProt:
F8DQ04
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All DBs
Position
complement(887554..888948)
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AA seq
464 aa
AA seq
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MSGRVTLLGAGPGNPELLTLIGKRRLGEADVVLYDRLIDPSLLSFTNDDATLVDVGKMPL
HHKVKQSQINEMLVDYANLGKKVVRLKAGDPYVFGRGGEEAQILQQQGINFEIIPGITSA
IAGLAAAGIPITHRDFASSFHVITGHHKKDGQQLDWENIANQEGTLVFLMGMAQLPNICH
QLIAHGKAVETPVAIIQWATQWRQKMVSGDLSNIVELVNKNGLSSPALIVVGNVVKLSKQ
LNVAKPLAGVHVLVPYSKRQRLFNCLEDLGATADFYQRSIVESAPAKLPVLDSYSSILFD
DYLAYKEFIKLLTASKKDIRALVGKKILAGNQSVANHLAKQGLLVDEVVATNKLSDDVLE
VGGQNSSYSHKEFLSLYQRKEQTHELPFDLAEFNAVIFPSTASLRDFKSTLNEEQFKQLK
DLTAFVMGQSIYDLATQNGFKKVINCQPNIKATIEQVKEELASE
NT seq
1395 nt
NT seq
+upstream
nt +downstream
nt
atgagtggtagagtaacgctcctcggtgcaggtcctgggaatcctgaactattaacatta
atcggtaaacggcggctgggagaggctgacgtagtattatatgatcggttaattgatcca
tcattattatcatttacaaatgatgatgcgaccctagttgatgttggaaaaatgcctctg
caccataaagtgaagcagtcccaaatcaatgagatgttagttgattatgcaaacttaggg
aaaaaagtggttcggttaaaagctggcgacccatatgtctttggccgtggtggcgaagag
gctcagatactacaacagcagggaattaactttgaaattattcctggaattactagtgcc
attgctgggttagcggctgcgggaattccgattacccatcgtgattttgcgtcgagcttc
cacgtgattacgggacatcataaaaaggatgggcagcaactcgattgggaaaacatcgct
aaccaagaaggaacgcttgttttcttgatggggatggcgcaacttcctaatatatgtcat
caattgatagctcatggaaaagcggtggaaacccccgttgcaattattcaatgggcaact
caatggcgacaaaagatggtcagtggtgatctttcaaatattgtggaattggtaaataaa
aacgggttatcatcaccagcattaatagtggtagggaatgttgttaagcttagtaagcag
ttgaatgttgctaagccgcttgcaggagtccatgtattagtaccatatagtaagaggcag
cgattatttaactgcttggaagatttaggcgcaactgcggacttttatcagcgatcaata
gtagaatccgccccagctaagttacccgttcttgattcatattcgtcaatcctatttgat
gattatcttgcttataaagaatttattaaattgcttacagcaagcaaaaaagatattcgc
gcattggtaggtaaaaagattcttgcaggtaatcaaagtgttgccaaccatcttgcaaaa
caggggttgttggtagatgaagttgttgcaacgaacaaactttctgatgatgtacttgaa
gttggtggccaaaattcgtcttattcacataaagaatttcttagtctctaccaacgaaaa
gaacaaacacatgagttaccgtttgaccttgcagaatttaatgcagtgattttccctagc
actgctagtctacgggattttaagagtacgttaaatgaagagcagtttaagcaattaaag
gacctaacagcctttgtgatgggacaatccatttatgatcttgcaacgcagaatggtttt
aaaaaagtaatcaattgtcagccaaatattaaagcaacaattgagcaggtaaaggaggag
ttagcgagtgaataa
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