KEGG   Lynx rufus (bobcat): 124503878
Entry
124503878         CDS       T08475                                 
Name
(RefSeq) 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-1
  KO
K05858  phosphatidylinositol phospholipase C, beta [EC:3.1.4.11]
Organism
lruf  Lynx rufus (bobcat)
Pathway
lruf00562  Inositol phosphate metabolism
lruf01100  Metabolic pathways
lruf04015  Rap1 signaling pathway
lruf04020  Calcium signaling pathway
lruf04022  cGMP-PKG signaling pathway
lruf04062  Chemokine signaling pathway
lruf04070  Phosphatidylinositol signaling system
lruf04071  Sphingolipid signaling pathway
lruf04072  Phospholipase D signaling pathway
lruf04081  Hormone signaling
lruf04082  Neuroactive ligand signaling
lruf04261  Adrenergic signaling in cardiomyocytes
lruf04270  Vascular smooth muscle contraction
lruf04310  Wnt signaling pathway
lruf04371  Apelin signaling pathway
lruf04540  Gap junction
lruf04611  Platelet activation
lruf04613  Neutrophil extracellular trap formation
lruf04621  NOD-like receptor signaling pathway
lruf04713  Circadian entrainment
lruf04720  Long-term potentiation
lruf04723  Retrograde endocannabinoid signaling
lruf04724  Glutamatergic synapse
lruf04725  Cholinergic synapse
lruf04726  Serotonergic synapse
lruf04728  Dopaminergic synapse
lruf04730  Long-term depression
lruf04742  Taste transduction
lruf04750  Inflammatory mediator regulation of TRP channels
lruf04911  Insulin secretion
lruf04912  GnRH signaling pathway
lruf04915  Estrogen signaling pathway
lruf04916  Melanogenesis
lruf04918  Thyroid hormone synthesis
lruf04919  Thyroid hormone signaling pathway
lruf04921  Oxytocin signaling pathway
lruf04922  Glucagon signaling pathway
lruf04924  Renin secretion
lruf04925  Aldosterone synthesis and secretion
lruf04926  Relaxin signaling pathway
lruf04927  Cortisol synthesis and secretion
lruf04928  Parathyroid hormone synthesis, secretion and action
lruf04929  GnRH secretion
lruf04933  AGE-RAGE signaling pathway in diabetic complications
lruf04934  Cushing syndrome
lruf04935  Growth hormone synthesis, secretion and action
lruf04961  Endocrine and other factor-regulated calcium reabsorption
lruf04970  Salivary secretion
lruf04971  Gastric acid secretion
lruf04972  Pancreatic secretion
lruf04973  Carbohydrate digestion and absorption
lruf05010  Alzheimer disease
lruf05016  Huntington disease
lruf05017  Spinocerebellar ataxia
lruf05022  Pathways of neurodegeneration - multiple diseases
lruf05142  Chagas disease
lruf05143  African trypanosomiasis
lruf05146  Amoebiasis
lruf05163  Human cytomegalovirus infection
lruf05200  Pathways in cancer
lruf05415  Diabetic cardiomyopathy
lruf05417  Lipid and atherosclerosis
Module
lruf_M00130  Inositol phosphate metabolism, PI=> PIP2 => Ins(1,4,5)P3 => Ins(1,3,4,5)P4
Brite
KEGG Orthology (KO) [BR:lruf00001]
 09100 Metabolism
  09101 Carbohydrate metabolism
   00562 Inositol phosphate metabolism
    124503878
 09130 Environmental Information Processing
  09132 Signal transduction
   04015 Rap1 signaling pathway
    124503878
   04310 Wnt signaling pathway
    124503878
   04371 Apelin signaling pathway
    124503878
   04020 Calcium signaling pathway
    124503878
   04070 Phosphatidylinositol signaling system
    124503878
   04072 Phospholipase D signaling pathway
    124503878
   04071 Sphingolipid signaling pathway
    124503878
   04022 cGMP-PKG signaling pathway
    124503878
  09133 Signaling molecules and interaction
   04082 Neuroactive ligand signaling
    124503878
   04081 Hormone signaling
    124503878
 09140 Cellular Processes
  09144 Cellular community - eukaryotes
   04540 Gap junction
    124503878
 09150 Organismal Systems
  09151 Immune system
   04611 Platelet activation
    124503878
   04613 Neutrophil extracellular trap formation
    124503878
   04621 NOD-like receptor signaling pathway
    124503878
   04062 Chemokine signaling pathway
    124503878
  09152 Endocrine system
   04911 Insulin secretion
    124503878
   04922 Glucagon signaling pathway
    124503878
   04929 GnRH secretion
    124503878
   04912 GnRH signaling pathway
    124503878
   04915 Estrogen signaling pathway
    124503878
   04921 Oxytocin signaling pathway
    124503878
   04926 Relaxin signaling pathway
    124503878
   04935 Growth hormone synthesis, secretion and action
    124503878
   04918 Thyroid hormone synthesis
    124503878
   04919 Thyroid hormone signaling pathway
    124503878
   04928 Parathyroid hormone synthesis, secretion and action
    124503878
   04916 Melanogenesis
    124503878
   04924 Renin secretion
    124503878
   04925 Aldosterone synthesis and secretion
    124503878
   04927 Cortisol synthesis and secretion
    124503878
  09153 Circulatory system
   04261 Adrenergic signaling in cardiomyocytes
    124503878
   04270 Vascular smooth muscle contraction
    124503878
  09154 Digestive system
   04970 Salivary secretion
    124503878
   04971 Gastric acid secretion
    124503878
   04972 Pancreatic secretion
    124503878
   04973 Carbohydrate digestion and absorption
    124503878
  09155 Excretory system
   04961 Endocrine and other factor-regulated calcium reabsorption
    124503878
  09156 Nervous system
   04724 Glutamatergic synapse
    124503878
   04725 Cholinergic synapse
    124503878
   04728 Dopaminergic synapse
    124503878
   04726 Serotonergic synapse
    124503878
   04720 Long-term potentiation
    124503878
   04730 Long-term depression
    124503878
   04723 Retrograde endocannabinoid signaling
    124503878
  09157 Sensory system
   04742 Taste transduction
    124503878
   04750 Inflammatory mediator regulation of TRP channels
    124503878
  09159 Environmental adaptation
   04713 Circadian entrainment
    124503878
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    124503878
  09172 Infectious disease: viral
   05163 Human cytomegalovirus infection
    124503878
  09174 Infectious disease: parasitic
   05146 Amoebiasis
    124503878
   05142 Chagas disease
    124503878
   05143 African trypanosomiasis
    124503878
  09164 Neurodegenerative disease
   05010 Alzheimer disease
    124503878
   05016 Huntington disease
    124503878
   05017 Spinocerebellar ataxia
    124503878
   05022 Pathways of neurodegeneration - multiple diseases
    124503878
  09166 Cardiovascular disease
   05417 Lipid and atherosclerosis
    124503878
   05415 Diabetic cardiomyopathy
    124503878
  09167 Endocrine and metabolic disease
   04933 AGE-RAGE signaling pathway in diabetic complications
    124503878
   04934 Cushing syndrome
    124503878
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   04131 Membrane trafficking [BR:lruf04131]
    124503878
Enzymes [BR:lruf01000]
 3. Hydrolases
  3.1  Acting on ester bonds
   3.1.4  Phosphoric-diester hydrolases
    3.1.4.11  phosphoinositide phospholipase C
     124503878
Membrane trafficking [BR:lruf04131]
 Exocytosis
  Calcium ion-dependent exocytosis
   Phospholipases
    124503878
 Endocytosis
  Macropinocytosis
   Phospholipase C
    124503878
SSDB
Motif
Pfam: PI-PLC-X PLC-beta_C PI-PLC-Y PLCB1-4-like_EFh EF-hand_like
Other DBs
NCBI-GeneID: 124503878
NCBI-ProteinID: XP_046925124
LinkDB
Position
Unknown
AA seq 1157 aa
MQANASVIYIFQEWTNEVFSLATNLLAQNMSRDAFLEKAYTKLKLQVTPEGRIPLKNIYR
LFSADRKRVETALEACSLPSSRNDSIPQEDFTPEVYRVFLNNLCPRPEIDNIFSEFGAKS
KPYLTVDQMMDFINLKQRDPRLNEILYPPLKQEQVQVLIEKYEPNDSLAKKGQISVDGFM
RYLSGEENGVVSPEKLDLNEDMSQPLSHYFINSSHNTYLTAGQLAGNSSVEMYRQVLLSG
CRCVELDCWKGRTAEEEPVITHGFTMTTEISFKEVIEAIAECAFKTSPFPILLSFENHVD
SPKQQAKMAEYCRLIFGDALLMEPLEKYPLESGVPLPSPMDLMYKILVKNKKKSHKSSEG
SGKKKLSEQASNTYSDSSSVFEPSSPGAGEADTESDDDDDDDDCKKSSMDEGTAGSEAMA
TEEMSNLVNYIQPVKFESFETSKKRNRSFEMSSFVETKGLEQLTKSPVEFVEYNKMQLSR
IYPKGTRVDSSNYMPQLFWNAGCQMVALNFQTVDLAMQINMGMYEYNGKSGYRLKPEFMR
RPDKHFDPFTEGIVDGIVANTLSVKIISGQFLSDKKVGTYVEVDMFGLPVDTRRKAFKTK
TSQGNAVNPVWEEEPIVFKKVVLPSLACLRIAVYEEGGKFIGHRILPVQAIRPGYHYICL
RNERNQPLMLPAVFVYIEVKDYVPDTYADVIEALSNPIRYVNLMEQRAKQLAALTLEDEE
EVKKEADPGETPSEAPSEARTTPAENGVNHTTSLAPKPPSQAPHSQPAPGSVKAPAKTED
LIQSVLTEVEAQTIEELKQQKPFVKLQKKHYKEMKDLVKRHHKKTTDLIKEHTTKYNEIQ
NDYLRRRAALEKTAKKDSKKKSEPSSPDHGSSTIEQDLAALDAEMTQKLIDLKDKQQQQL
LNLRQEQYYSEKYQKREHIKLLIQKLTDVAEECQNNQLKKLKEICEKEKKELKKKMDKKR
QEKITEAKSKDKSQMEEEKTEMIRSYIQEVVQYIKRLEEAQSKRQEKLVEKHKEIRQQIL
DEKPKDSTSFEIIPLHIQYEALKFDIDMKESNKSRNNMESAVTQGNETDQQGTVPPHSCR
KLAMRIPLFPPTLLPPTLKLSSGDYHPSGQILIQEVWMGLEVCISNQLPGDALAATFPQT
AFDKQGSSTFLPPGCNT
NT seq 3474 nt   +upstreamnt  +downstreamnt
atgcaagctaatgcaagtgtgatttacatctttcaggaatggacaaatgaggttttcagt
ttggcaacaaacctgctggcccaaaacatgtccagagacgcatttctggaaaaagcctat
acgaagcttaagctgcaagtcactccagaagggcgcattcctctcaaaaacatataccgc
ttgttctcagcagaccggaagcgagttgaaactgctttagaggcttgtagtcttccatct
tcaaggaatgattcaatacctcaagaagatttcactccagaagtgtacagagttttcctg
aacaacctttgccctcgacctgaaattgataacatcttttctgaatttggtgccaaaagc
aaaccataccttacggttgatcagatgatggattttatcaacctgaagcagcgagatcct
cggctaaatgaaatactttacccacctttaaagcaagagcaagtccaagtactgattgag
aagtatgagcccaacgatagccttgccaaaaaaggacagatatcagtggatggctttatg
cgctatctgagtggagaagaaaatggagtcgtttcgcctgagaaactggatttgaatgaa
gatatgtctcagcccctttctcactatttcatcaattcctcacacaacacctacctcaca
gctggccagttggctggaaattcctctgttgagatgtatcgccaagtgctcctgtctggt
tgtcgctgtgtggagttggactgctggaaaggacggactgcggaagaggaaccagtcatc
acccatgggttcaccatgacaactgaaatatccttcaaggaagtgatagaagcaattgct
gagtgtgcatttaagacgtcaccttttccaattctgctttcatttgagaaccacgtagat
tccccaaagcagcaagccaagatggcagagtattgccgactgatctttggagatgctctt
ctcatggaaccactggaaaaatacccactggaatctggagttcctcttccaagccctatg
gatttaatgtacaaaattttggtgaaaaataagaagaaatcgcataagtcatcagaagga
agtggcaaaaagaagctctcagaacaagcctccaacacgtacagtgactcctccagcgtg
tttgagccctcatctccaggagccggggaagctgatactgagagtgacgacgatgatgat
gatgacgactgtaaaaaatcttcaatggatgagggtactgctggcagtgaggccatggcc
acagaagagatgtctaacctggtgaactatattcagccagtcaagtttgagtcctttgaa
acttcaaaaaaaagaaatagaagttttgaaatgtcttccttcgtggaaaccaaaggactc
gagcaactgacaaagtctccagtggaatttgtagaatataacaaaatgcagctcagcagg
atatatccaaaaggaacccgtgtggattcatccaactacatgcctcagctcttctggaat
gctggttgccaaatggttgcacttaattttcaaactgtggacctggctatgcaaataaat
atggggatgtatgaatacaatgggaaaagtggctacagattaaagccagagttcatgagg
agacccgacaagcactttgatccattcaccgaaggcatcgtagatgggatagtggccaac
actttatctgtgaagattatttcaggtcagtttctttctgataagaaagttgggacctat
gtggaagtggatatgtttggtttgcctgtggatacaaggaggaaggcatttaagaccaaa
acatcacaaggaaatgctgtaaatcctgtctgggaagaagagcccattgtgttcaaaaag
gtggttcttccttctctggcctgtttgaggatagcagtttatgaagaaggaggtaaattt
atcggtcaccggatcttgcctgtacaggcaattcggccaggctatcactacatctgtctg
cggaatgagaggaaccagcctctgatgctcccagctgtctttgtctacatagaggtgaaa
gactatgtcccagatacatatgcagatgtgattgaagctttgtcaaatccaatacgatat
gtgaatctgatggagcagagagcaaagcaactggctgctttgacactggaagatgaagaa
gaagtaaagaaagaggctgatcctggggaaacaccatcagaagctccaagtgaagccagg
acaactccagcagaaaacggagtgaatcacactacatccctggcacccaaaccaccctcc
caggctccccacagccaaccagctccaggttctgtaaaggcacctgccaaaacagaagat
cttattcagagtgttttaacagaagtggaagcacagactatcgaagagctaaagcaacag
aaaccgtttgtgaaacttcaaaagaagcactacaaagaaatgaaagacctggtgaaaaga
caccacaagaaaaccactgaccttatcaaagaacacactacaaaatataatgaaattcag
aatgactacttgagaaggagggcagctttggaaaagacagccaaaaaggatagtaagaaa
aaatcagaacccagcagtcctgaccatggttcatcaacaattgagcaagatcttgctgcc
ctagatgctgaaatgacccaaaagttaatagacttgaaggacaaacaacagcagcagctg
cttaatcttcgacaagaacagtattacagtgagaaataccagaagcgagaacatattaaa
ctgcttattcagaaattgacggatgttgccgaagaatgtcagaacaatcagctgaagaag
ctcaaagaaatctgtgagaaggagaagaaggaattaaagaagaaaatggataaaaaaagg
caggagaagatcacagaagctaaatccaaagacaaaagtcaaatggaagaggaaaagaca
gagatgatccggtcatacatccaggaggtggtacagtacatcaagaggttagaagaggca
caaagtaaacggcaagaaaaacttgtagagaaacacaaggagatccgtcagcagatcctg
gatgaaaagcccaaggatagcaccagctttgaaataatccctcttcacatccagtatgaa
gctttgaagtttgacatagatatgaaggaaagtaacaaaagcagaaacaatatggaaagt
gcagtaactcaagggaatgaaactgaccagcaggggacggttcctcctcattcttgtcgg
aaacttgccatgaggatccctctgtttcccccaactttactccccccaaccctcaagctc
tcaagtggtgactaccatccttccggccagattctgattcaggaggtctggatgggactt
gaggtctgcatttctaaccagcttccaggggatgcccttgctgccacatttccacagact
gcatttgacaagcagggatctagtacattcctacctcctggctgtaacacctag

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