Lynx rufus (bobcat): 124504579
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Entry
124504579 CDS
T08475
Name
(RefSeq) folylpolyglutamate synthase, mitochondrial isoform X1
KO
K01930
folylpolyglutamate synthase [EC:
6.3.2.17
]
Organism
lruf
Lynx rufus (bobcat)
Pathway
lruf00790
Folate biosynthesis
lruf01100
Metabolic pathways
lruf01240
Biosynthesis of cofactors
lruf01523
Antifolate resistance
lruf04981
Folate transport and metabolism
Brite
KEGG Orthology (KO) [BR:
lruf00001
]
09100 Metabolism
09108 Metabolism of cofactors and vitamins
00790 Folate biosynthesis
124504579
09150 Organismal Systems
09154 Digestive system
04981 Folate transport and metabolism
124504579
09160 Human Diseases
09176 Drug resistance: antineoplastic
01523 Antifolate resistance
124504579
Enzymes [BR:
lruf01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.17 tetrahydrofolate synthase
124504579
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Ortholog
Paralog
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Motif
Pfam:
Mur_ligase_M
Mur_ligase_C
Motif
Other DBs
NCBI-GeneID:
124504579
NCBI-ProteinID:
XP_046925973
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Position
Unknown
AA seq
580 aa
AA seq
DB search
MSQARRHLRPALFLAAVSARVATTGVAARRGLSAWPAPQEPGMEYQDAVRALNTLQTNAG
YLEQVKRQRGDPQAQLEAMKLYLARSGLQVEDLDQLNIIHVTGTKGKGSTCAFTERILRS
YGLKTGFFSSPHLVQVRERIRINGQPISPELFTKHFWPLYHRLEETKDSSSYVSMPAYFR
FLTLMAFHVFLQEKVDLAVVEVGIGGAYDCTNIIRKPAVCGISSLGIDHTSILGDTVEEI
AWQKGGIFKRGVPAFTVLQPDGPLAVLRDRAQQISCPLYLCPPLEALEEGGPPLTLGLEG
EHQRSNAALALQLARCWLQQKDYRGIGELKVSRPSLLRQMPLAPVFQPTTHMRHGLRDTE
WLGRTQVLRRGPLTWYLDGAHTASSMQACVRWFRQALHRRPRPSRGSEVLVLLFNSTGDR
DPAALLKLLQPCQFDYAVFCPNLTEVSTVGNADQQNFMVTLDQVLLRCLAHQQHWSRLDE
EQAGPEPGEPTSSLLAPHPPEPRSTSSLVFSCISHALLWISQGRDPVFQPPSPPQGLFAH
PVAGSGAGVLREAAAIHVLVTGSLHLVGGVLKLLEPALSQ
NT seq
1743 nt
NT seq
+upstream
nt +downstream
nt
atgtcgcaggcacgccgccacctgcgacccgctcttttcctggcggcggtttctgcgcgc
gttgcaactaccggggtagcggctcggcgagggttgagcgcgtggcccgcgccgcaggag
cccggcatggagtaccaggatgctgtgcgcgcactgaacaccctgcagaccaatgctggc
tatctggagcaggtaaagcgccagcggggtgaccctcaggcacagctggaagccatgaag
ctgtacttggcacggagtgggctgcaggtggaagacttggaccagctgaacatcattcac
gtcactgggaccaaggggaagggttccacttgtgcctttactgaacgtattctccgaagc
tatggcctgaagacaggattctttagctctccccacctggtgcaggtgcgggagcggatc
cgcatcaacgggcagcccataagccctgagctcttcaccaagcacttctggcccctctac
caccggctggaggagaccaaggacagcagcagctatgtctccatgcccgcctacttccgc
ttcctcacgctcatggccttccacgtcttcctccaagagaaggtggacctggcagtggtg
gaggtgggcattggtggcgcttacgactgcaccaacatcatcaggaagcctgcggtgtgt
ggcatctcctctcttggcatcgaccacaccagcattctgggggacacggtggaggagatc
gcgtggcagaaagggggcatcttcaagcgtggcgtccccgccttcaccgtgctccagcct
gacggtcccctggccgtgctgagggaccgggcccagcagatctcatgtcctctctacctg
tgcccaccactggaagccctggaggaaggggggccgccgctgaccctgggcctggaggga
gagcaccagcggtccaatgccgccttggccttgcagctggctcgctgctggctacagcaa
aaggactaccggggcatcggggagctgaaggtgtccaggcccagtctcttgcggcagatg
cccctggcgcccgtgttccagcccacgacccacatgcggcatgggcttcgggacacggag
tggctgggccggacgcaggtgctgcggcgcgggcccctcacctggtacctggatggcgcg
cacaccgccagcagcatgcaggcctgcgtgcgctggttccgccaggcgctgcaccgccgc
ccgaggccaagccgcggctctgaggtgcttgtcctgcttttcaactccaccggagaccgg
gatcctgcagcactgctgaagctgctgcagccctgtcagtttgactatgctgttttctgc
cctaacctgacagaggtctcaactgttggcaatgcagaccagcagaacttcatggtgacc
ctggaccaggtgttgctccgctgccttgcacaccaacagcactggagccgcctggacgag
gagcaggccggcccggagcctggtgagcccacatcctcgctgctggctccccacccgccc
gagccccgtagcaccagctccctcgtcttcagctgcatctcccacgccttgctgtggatc
agtcaaggccgggaccctgtctttcagccacccagtcccccgcagggcctcttcgcccac
cctgtggcaggcagcggggccggcgtgctccgtgaggctgccgccatccacgtgctggtc
accggcagcctgcacctggtgggcggcgtcctgaagctgctggagccggccctgtcccag
tag
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