KEGG   Lynx rufus (bobcat): 124510409
Entry
124510409         CDS       T08475                                 
Name
(RefSeq) voltage-dependent L-type calcium channel subunit alpha-1S
  KO
K04857  voltage-dependent calcium channel L type alpha-1S
Organism
lruf  Lynx rufus (bobcat)
Pathway
lruf04010  MAPK signaling pathway
lruf04020  Calcium signaling pathway
lruf04022  cGMP-PKG signaling pathway
lruf04024  cAMP signaling pathway
lruf04260  Cardiac muscle contraction
lruf04261  Adrenergic signaling in cardiomyocytes
lruf04270  Vascular smooth muscle contraction
lruf04723  Retrograde endocannabinoid signaling
lruf04725  Cholinergic synapse
lruf04726  Serotonergic synapse
lruf04727  GABAergic synapse
lruf04911  Insulin secretion
lruf04912  GnRH signaling pathway
lruf04921  Oxytocin signaling pathway
lruf04924  Renin secretion
lruf04925  Aldosterone synthesis and secretion
lruf04927  Cortisol synthesis and secretion
lruf04929  GnRH secretion
lruf04934  Cushing syndrome
lruf04935  Growth hormone synthesis, secretion and action
lruf05010  Alzheimer disease
lruf05020  Prion disease
lruf05022  Pathways of neurodegeneration - multiple diseases
lruf05207  Chemical carcinogenesis - receptor activation
lruf05410  Hypertrophic cardiomyopathy
lruf05412  Arrhythmogenic right ventricular cardiomyopathy
lruf05414  Dilated cardiomyopathy
Brite
KEGG Orthology (KO) [BR:lruf00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    124510409
   04020 Calcium signaling pathway
    124510409
   04024 cAMP signaling pathway
    124510409
   04022 cGMP-PKG signaling pathway
    124510409
 09150 Organismal Systems
  09152 Endocrine system
   04911 Insulin secretion
    124510409
   04929 GnRH secretion
    124510409
   04912 GnRH signaling pathway
    124510409
   04921 Oxytocin signaling pathway
    124510409
   04935 Growth hormone synthesis, secretion and action
    124510409
   04924 Renin secretion
    124510409
   04925 Aldosterone synthesis and secretion
    124510409
   04927 Cortisol synthesis and secretion
    124510409
  09153 Circulatory system
   04260 Cardiac muscle contraction
    124510409
   04261 Adrenergic signaling in cardiomyocytes
    124510409
   04270 Vascular smooth muscle contraction
    124510409
  09156 Nervous system
   04727 GABAergic synapse
    124510409
   04725 Cholinergic synapse
    124510409
   04726 Serotonergic synapse
    124510409
   04723 Retrograde endocannabinoid signaling
    124510409
 09160 Human Diseases
  09161 Cancer: overview
   05207 Chemical carcinogenesis - receptor activation
    124510409
  09164 Neurodegenerative disease
   05010 Alzheimer disease
    124510409
   05020 Prion disease
    124510409
   05022 Pathways of neurodegeneration - multiple diseases
    124510409
  09166 Cardiovascular disease
   05410 Hypertrophic cardiomyopathy
    124510409
   05412 Arrhythmogenic right ventricular cardiomyopathy
    124510409
   05414 Dilated cardiomyopathy
    124510409
  09167 Endocrine and metabolic disease
   04934 Cushing syndrome
    124510409
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04040 Ion channels [BR:lruf04040]
    124510409
Ion channels [BR:lruf04040]
 Voltage-gated cation channels
  Calcium channel, voltage-gated (Cav)
   124510409
SSDB
Motif
Pfam: Ion_trans Ca_chan_IQ GPHH PKD_channel CAC1F_C
Other DBs
NCBI-GeneID: 124510409
NCBI-ProteinID: XP_046933225
LinkDB
Position
Unknown
AA seq 1871 aa
MEPSSPQDEGLRKKQPKKPVPEILPRPPRALFCLTLQNPLRKACINIVEWKPFETIILLT
IFANCVALAVYLPMPEDDNNTLNLGLEKLEYFFLIVFSIEAAMKIIAYGFLFHQDAYLRS
GWNVLDFIIVFLGVFTVILEQVNVIQSNTAPMSSKGAGLDVKALRAFRVLRPLRLVSGVP
SLQVVLNSIFKAMLPLFHIALLVLFMVIIYAIIGLELFKGKMHKTCYFIGTDIVATVENE
KPSPCARTGSGRPCTINGSECRGGWPGPNHGITHFDNFGFSMLTVYQCITMEGWTDVLYW
VNDAIGNEWPWIYFVTLILLGSFFILNLVLGVLSGEFTKEREKAKSRGTFQKLREKQQLE
EDLRGYMSWITQGEVMDVEDLREGKLSLDEGGSDTESLYEIEGLNKIIQFVRHWRQWNRI
FRWKCHDVIKSRVFYWLVILVVALNTLSIASEHHNQPLWLTHLQDVANRVLLALFAVEML
LKMCGLGLRQYFMSIFNRFDCFVVCSGVLELLLVESGAMTPLGISVLRCIRLLRIFKITK
YWTSLSNLVASLLNSIRSIASLLLLLFLFIIIFALLGMQLFGGRYDFEDTEVRRSNFDNF
PQALISVFQVLTGEDWNSVMYNGIMAYGGPSYPGVLVCIYFIILFVCGNYILLNVFLAIA
VDNLAEAESLTSAQKAKAEEKKRRKMSKGLPDKSEEEKSVMAKKLEQKPKGEGIPTTAKL
KIDEFESNVNEVKDPYPSADFPGDDEEDEPEIPVSPRPRPLAELQLKEKAVPIPEASSFF
IFSPTNKIRVLCHRIVNATWFTNFILLFILLSSAALAAEDPIRAESVRNQILGYFDIAFT
SVFTVEIVLKMTTYGAFLHKGSFCRNYFNILDLLVVAVSLISMGLESSAISVVKILRVLR
VLRPLRAINRAKGLKHVVQCVFVAIRTIGNIVLVTTLLQFMFACIGVQLFKGKFFSCNDL
SKMTEKECRGYYYVYKDGDPTQMELRPRQWIHSDFHFDNVLSAMMSLFTVSTFEGWPQLL
YQAIDSYKEDTGPVYNNRVEMAIFFIIYIILIAFFMMNIFVGFVIVTFQEQGETEYKNCE
LDKNQRQCVQYALKARPLRCYIPKNPYQYQVWYVVTSSYFEYLMFALIMLNTICLGMQHY
NQSEEMNHISDILNVAFTIIFTLEMVLKLMAFKARGYFGDPWNVFDFLIVIGSIIDVILS
EIDTFLASSGGLYCLGGGCGNVDPDESARISSAFFRLFRVMRLIKLLSRAEGVRTLLWTF
IKSFQALPYVALLIVMLFFIYAVIGMQMFGKIAMVDGTQINRNNNFQTFPQAVLLLFRCA
TGEAWQEILLACSYGKLCDPESDYAPGEEYTCGTNFAYYYFVSFYMLCAFLIINLFVAVI
MDNFDYLTRDWSILGPHHLDEFKAIWAEYDPEAKGRIKHLDVVTLLRRIQPPLGFGKFCP
HRVACKRLVGMNMPLNSDGTVTFNATLFALVRTALKIKTEGNFEQANEELRAIIKKIWKR
TSMKLLDQVIPPIGDDEVTVGKFYATFLIQEHFRKFMKRQEEYYGYRPKKDTVQIQAGLR
TIEEEAAPEIRRTISGDLTAEEELERAMVEAAMEEGIFRRTGGLFGQVDNFMERTNSLPP
VMANQRPLQFAEIEMEELESPVFLEDFPQDPRTNPLAHANTNNANANVACDNSSHSNSQL
FSSIRYEREFPGETETPAARGGAFGQPRSVLGAHSKSCVEKLKGQLAQREMPGAQASPTP
CQRAGAEPPLPGERRDPTPGPEEASHHGRTKESSSRCQTPATARLIQEALVRGGLDTLAA
DADFVTVTGRALADACQMEPEDVEVAATELLKRQESPEGMASAQGRLSLGSSLGSLDQHQ
GSQETLIPRRL
NT seq 5616 nt   +upstreamnt  +downstreamnt
atggagccatcctcaccccaggatgagggcctgaggaagaaacagcccaagaagcccgtt
cctgagattctgccaaggccaccccgggccttgttctgcttgaccctccagaaccccctg
aggaaggcctgcatcaacatcgtggaatggaaacccttcgagacaatcatcttgctcacc
atctttgccaactgtgtggccctggctgtgtacctgcccatgcccgaagatgacaacaac
actctcaaccttggtctggagaaactggagtatttcttcctcatcgtcttctcaatcgaa
gccgccatgaagatcattgcctatggcttcctgttccaccaggatgcctacctgcgcagc
ggctggaatgtgctagacttcatcatcgtcttcctgggggttttcaccgtgattctggaa
caggttaacgtcatccaaagcaacaccgccccgatgagcagcaaaggggctggcctggac
gtcaaggccctgagagcctttcgtgtgctcagacccctccggcttgtgtcgggggtgccg
agcctgcaggtggtcctcaactccatcttcaaggccatgcttcccctgttccacatcgcc
ctgctcgtcctctttatggtcatcatctatgccatcatcgggctggagctcttcaagggc
aaaatgcacaagacctgctacttcattgggacagatatcgtggccacggtagagaacgag
aagccttcaccctgtgccaggacgggctcgggacgcccgtgcaccatcaatggcagcgag
tgtcggggcggctggccggggcccaaccacggcatcacgcactttgacaactttggcttc
tccatgctcaccgtgtaccagtgcatcaccatggaggggtggaccgatgtcctctactgg
gtcaatgatgccatcgggaacgagtggccctggatctattttgtcaccctcattctgctg
ggatccttcttcattctcaacctggtgctgggtgtcctgagcggggaattcactaaggag
cgggagaaggccaagtccaggggaaccttccaaaagctccgggagaagcagcagctggaa
gaggaccttcggggctacatgagctggatcacgcagggcgaggtcatggacgttgaggac
ttgagagaagggaagctgtctctggatgaaggaggctccgacacagagagcctgtatgaa
atcgagggcttgaacaaaatcatccagtttgtccgccactggaggcagtggaaccgcatc
tttcgctggaagtgccacgatgtgatcaagtccagagtcttctattggctggtgatcctg
gtcgttgccctcaacaccctgtctatcgcctcagagcaccacaaccagcctctctggttg
acccatttgcaagacgttgccaaccgcgtgctgctggccctcttcgccgtcgagatgctg
ctgaagatgtgcgggctgggcctgcgccagtacttcatgtccatcttcaaccgcttcgac
tgcttcgtggtgtgcagcggcgtcctggagctgctgctggtggagtcaggtgccatgacg
cccctgggcatctccgtgctgcgctgcatccgcctcctgcggatcttcaagatcaccaag
tactggacgtcgctgagcaacctggtggcatccctgctcaactccatccgctccatcgcc
tccctgctgctgctgcttttcctcttcatcatcatcttcgccctgctgggcatgcagctc
ttcgggggcaggtacgacttcgaggacacggaggtgcggcgcagcaactttgacaacttc
ccgcaggccctcatcagcgtcttccaggtcctaacaggtgaagactggaattctgtgatg
tacaacgggatcatggcctacggcgggccgtcctaccctggggtgctcgtgtgcatttat
ttcatcatcctttttgtctgtggcaattatatcctgctcaatgtcttcctggccatcgct
gtggacaacctggctgaggcagagagcctgacttctgcccagaaggccaaagctgaggag
aaaaaacgcaggaagatgtccaagggtcttccagataagtcagaggaagagaagtcagta
atggccaagaagctggaacagaaacccaagggtgaaggcatccctaccactgccaagctg
aaaattgatgaatttgaatctaatgtcaatgaagtgaaggatccctacccctcagctgac
ttcccaggagatgatgaggaagatgagcccgagatcccagtgagcccccgaccacgcccg
ctggctgagctgcagctcaaagagaaggcagtgcccatcccagaagccagctccttcttc
attttcagccccaccaacaagatccgtgtcttgtgtcatcgcattgtcaacgctacctgg
ttcaccaacttcatccttcttttcatcctgctcagcagtgccgcactggccgcggaggac
cccatccgcgccgagtccgtgaggaatcagatccttgggtatttcgacatcgcgttcacc
tctgtcttcactgtggagattgtcctcaagatgacgacctacggtgccttcctgcacaag
ggctccttctgccgcaactacttcaacatcctggacctgctggtggtggccgtgtccctc
atctccatgggactcgagtccagcgccatctccgtggtgaaaatcctgagggtgctgagg
gtgctccggcccctgcgggccatcaacagagccaaggggctgaagcacgtggtgcaatgt
gtgtttgtggccatccgcacaatcgggaacatcgtcctcgtcaccaccctcctgcagttc
atgtttgcctgcatcggcgtccagcttttcaaggggaagttcttcagctgcaatgactta
tccaagatgacagagaaggagtgcaggggctattactatgtgtacaaggatggggacccc
acccagatggagctgcgcccccgccagtggatacacagcgacttccatttcgacaacgtg
ctctcggccatgatgtcactcttcacggtctccacctttgagggatggcctcagctgctt
taccaggccatagactcatacaaggaagacacaggccccgtctacaacaaccgagtggag
atggccatcttcttcatcatctacatcatcctcattgccttcttcatgatgaacatcttt
gtgggcttcgttattgtcaccttccaggagcagggggagactgagtacaagaactgtgaa
ctggacaagaaccagcgccagtgtgtgcaatatgccctgaaggcccgcccgctgaggtgc
tacatccccaaaaacccataccagtaccaggtgtggtatgtcgtcacctcctcctacttt
gagtacctgatgtttgccctcatcatgctcaacaccatctgcctgggcatgcagcactac
aaccagtcagaggagatgaaccacatctcagacatcctcaacgtggccttcaccatcatc
ttcaccctggagatggtcctcaagctcatggcgttcaaggccaggggctattttggagac
ccctggaatgtgtttgacttcttgattgtcatcggcagcatcatcgatgtcattctcagt
gaaatcgacactttcctggcctccagcgggggactgtattgcctgggtggaggctgcggg
aacgttgacccagacgagagcgcccggatctccagcgccttctttcgcctgttccgggtc
atgaggctgatcaagctgcttagccgggcagagggagtgcgcactctgctgtggacgttc
atcaagtccttccaggccctgccatacgtggccctgctcatcgtcatgctcttcttcatc
tacgccgtcatcggcatgcagatgtttggtaagatcgccatggtggacgggacccaaata
aaccggaacaacaacttccagaccttcccacaagctgtgttgctgctcttcaggtgtgcg
acaggtgaggcgtggcaggagatcctcctggcctgcagctacggcaagttgtgtgacccc
gaatcggattatgccccgggtgaggagtacacgtgtggcaccaacttcgcctactattac
ttcgtcagcttctacatgctctgcgccttcctgatcatcaacctgtttgtagctgtcatc
atggacaactttgactacctcacccgggactggtccatcctgggcccccatcacctggat
gagttcaaagccatttgggcagagtatgacccggaggctaagggcagaatcaaacacctg
gatgtggtgaccctgctgagacggatccaaccccctctgggctttgggaagttctgccca
caccgggtagcatgtaagcggctggtgggcatgaacatgcccttgaacagtgacggcacg
gtcaccttcaacgccactctcttcgccctggtccgcacagcactcaagatcaagacggaa
ggtaactttgagcaggccaatgaggagctgagggccatcatcaagaagatctggaagaga
accagcatgaagctcctggaccaggtcattcctccaataggagatgatgaggtgactgta
gggaagttctacgccacgtttctcatccaggagcacttccggaagttcatgaagcgccag
gaagagtattatgggtatcggcccaagaaggacactgtacagatccaggccggactgcgg
accattgaggaagaggcagccccagagatccggcgcaccatctcaggagacctgacagct
gaagaggagctggagagagccatggtggaggctgcgatggaggaaggaatattccggagg
actgggggcctgtttggccaggtggacaacttcatggaaaggaccaactccctgccccct
gtgatggccaaccagcgacccctccagtttgctgagatagagatggaagagctggaatca
cccgtcttcttggaggatttccctcaagatccacgcaccaaccctcttgctcatgccaac
accaataatgccaatgccaatgttgcctgtgacaacagcagccatagcaacagccagcta
ttttccagcatccgctatgaaagagagttccctggagagacagagacgcctgctgccaga
ggaggagcctttggccagccccgaagcgtcctgggagcccacagcaaatcctgtgtggaa
aagctaaaaggacagctggcccagagagaaatgcccggggcccaggcgtctcctaccccc
tgccagcgtgccggtgcagagcctcccctgcctggggagaggagggaccccaccccgggg
cctgaggaagcatcccaccacggtaggaccaaggagagtagttccaggtgccagactcca
gcgacagcccggctgatacaagaggctctggttcgaggaggcctggacaccttggcggct
gatgctgactttgtcacggtgacaggccgggccctggcagatgcctgccagatggaacca
gaggatgtggaggtggcagcaacagagctactgaaaagacaagagtccccagagggcatg
gccagtgcccagggacgcttgagcctcgggtcctcgctggggagccttgaccagcatcag
ggctcccaggagaccctgatcccccgcaggctgtga

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