Lynx rufus (bobcat): 124513344 Help Entry 124513344         CDS       T08475                                  Name (RefSeq) DNA topoisomerase 2-alpha   KO K03164   DNA topoisomerase II [EC:5.6.2.2] Organism lruf  Lynx rufus (bobcat) Pathway lruf01524   Platinum drug resistance Brite KEGG Orthology (KO) [BR:lruf00001]  09160 Human Diseases   09176 Drug resistance: antineoplastic    01524 Platinum drug resistance     124513344  09180 Brite Hierarchies   09182 Protein families: genetic information processing    03032 DNA replication proteins [BR:lruf03032]     124513344    03036 Chromosome and associated proteins [BR:lruf03036]     124513344 Enzymes [BR:lruf01000]  5. Isomerases   5.6  Isomerases altering macromolecular conformation    5.6.2  Enzymes altering nucleic acid conformation     5.6.2.2  DNA topoisomerase (ATP-hydrolysing)      124513344 DNA replication proteins [BR:lruf03032]  Eukaryotic type   DNA Topoisomerases    124513344 Chromosome and associated proteins [BR:lruf03036]  Eukaryotic type   Chromosome condensation proteins    Other regulators of chromosome condensation     124513344   Centrosome formation proteins    Centriole proteins     124513344 BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  DNA_topoisoIV TOPRIM_C DNA_gyraseB DTHCT HATPase_c Toprim Microp_apicomplexa_20 Motif Other DBs NCBI-GeneID:  124513344 NCBI-ProteinID:  XP_046937217 LinkDB All DBs Position Unknown AA seq 1534 aa AA seqDB search MEVSPLQPVNENMLINKTKKNEDAKKRLSIERIYQKKTQLEHILLRPDTYIGSVELVTQQ MWVYDEDIGINYREVTFVPGLYKIFDEILVNAADNKQRDPKMSCIRVTIDPENNLISIWN NGKGIPVVEHKVEKMYVPALIFGQLLTSSNYDDDEKKVTGGRNGYGAKLCNIFSTKFTVE TASREYKKMFKQTWMDNMGRAGEMELKPFNGEDYTCITFQPDLSKFKMQSLDKDIVALMV RRAYDIAGSTKDVKVFLNGNKLPVKGFRSYVDMYLKDKVDETGNPLKIIHEQVNPRWEVC LTMSEKGFQQISFVNSIATSKGGRHVDYIADQIVTKLVEVVKKKNKGGVAVKAHQVKNHM WIFVNALIENPTFDSQTKENMTLQVKSFGSTCHLSEKFIKAAIGCGIVESILNWVKFKAQ VQLNKKCSAVKHNRIKGIPKLDDANDAGGRNSNECTLILTEGDSAKTLAVSGLGVVGRDK YGVFPLRGKILNVREASHKQIMENAEINNIIKIVGLQYKKNYEDEDSLKTLRYGKIMIMT DQDQDGSHIKGLLINFIHHNWPSLLRHRFLEEFITPIVKVSKNKQEMAFYSLPEFEEWKS STPNHKKWKVKYYKGLGTSTSKEAKEYFADMKRHRIQFKYSGPEDDAAISLAFSKKQIDD RKEWLTHFMEDRRQRKLLGLPEDYLYGQTTTYLTYNDFINKELILFSNSDNERSIPSMVD GLKPGQRKVLFTCFKRNDKREVKVAQLAGSVAEMSSYHHGEMSLMMTIINLAQNFVGSNN LNLLQPIGQFGTRLHGGKDSASPRYIFTMLSPLARLLFPPKDDHTLKFLYDDNQRVEPEW YIPIIPMVLINGAEGIGTGWSCKIPNFDIREVVNNIRRLMDGEEPLPMLPSYKNFRGTIE ELAPNQYVISGEVAILNSTTIEISELPIRTWTQTYKEQVLEPMLNGTEKTPPLITDYREY HTDTTVKFVVKMTEEKLAEAERVGLHKVFKLQTSLTCNSMVLFDHVGCLKKYDTVLDILR DFFELRLKYYGLRKEWLLGMLGAESAKLNNQARFILEKIDGKIIIENKPKKELIKVLIQR GYDSDPVKAWKEAQQKVPDEEENEESDNENEAEKGDSVKDSGPTFNYLLDMPLWYLTKEK KDELCKLRNEKEQELETLKRKSPSDLWKEDLAAFIEELEAVETKEKQEEQIGLPGKGGKA KGKKIQMAEVLPSPCGKRVIPRVTIEMKAEAEKKIKKKIKSENTEGSPQENGMELEGLKQ RLEKKQKREPGTKTKKQTTLPFKPVKKGKKRNPWSDSESDMSSNESDFDVPPREMEPRRA ATKTKFTVDLDSDDDFSDFDEKTQDEDFVPSDVSPVKTKTSPPVPTNKELKPQKSATSVT DLDAGGAKDSVPPSLDSPAADFSAETEIINPVSKKKVAVKKTAAKSQSSTSTAGAKKRAA PKGTKKEPGLNSDVSQKPDPPKTKNRRKRKPSTSDDSDSNFEKMISKTVTSKKSKGESED FHLDLDSAVAPRAKSGRAKKPIKYLEESDEDDLF NT seq 4605 nt NT seq  +upstreamnt  +downstreamnt atggaggtgtcaccactgcagcctgtaaatgaaaatatgctaatcaacaaaacaaagaaa aatgaagatgctaagaaaagactgtctattgaaaggatctatcaaaagaaaacccaactg gaacatattttgctccgcccagacacctatattggctccgtggaattagtgacccagcaa atgtgggtttacgatgaagatattggcattaactatagggaagtcacctttgtccctggg ttgtacaaaatctttgatgagattctagtcaatgctgcagacaacaaacaaagggaccca aaaatgtcttgtattagagtcacaattgacccggaaaacaatttaattagtatatggaat aatgggaaaggtattcctgttgttgaacacaaagttgagaagatgtatgtcccagctctc atctttggacagctcctaacttctagtaactatgatgatgatgaaaagaaagtaacaggt ggtcgaaatggctatggggccaaattgtgtaacatattcagtaccaaatttactgtggaa acagccagtagagaatacaagaaaatgttcaaacagacatggatggataacatgggaagg gctggtgagatggaactcaagcccttcaatggggaagattatacatgtattaccttccag cctgatttgtccaagtttaaaatgcaaagcctagacaaagatattgttgcactaatggtc agaagagcatatgatattgccggatccactaaagatgtcaaagtgtttctcaatggaaat aagctgccagtaaaaggattccgtagctatgtagatatgtatttgaaggataaggtagat gaaactggcaatccgttgaaaattatccatgaacaagtaaaccccaggtgggaagtatgc ttaacaatgagtgaaaaaggctttcagcaaattagctttgtcaacagcattgctacttcc aagggtggcagacatgttgattatatagctgatcagattgtgactaaacttgttgaggtt gttaaaaagaagaacaagggtggtgttgcagtaaaagcacatcaggtgaaaaatcacatg tggatttttgtgaatgccttaattgaaaacccaacctttgattctcagacaaaagagaac atgactttacaagtcaagagctttggatcaacctgccatttaagtgaaaaattcatcaaa gctgcaattggttgtggtattgtagaaagcatactaaactgggtgaagtttaaggcccaa gtccagttaaacaagaagtgttcagctgtaaaacataacaggatcaagggaattcccaaa ctcgatgatgccaatgatgcagggggtcgaaactccaatgagtgtacacttatcctgact gagggagactcagctaaaactttggctgtttcaggccttggtgtggttgggagagacaaa tatggggttttcccgcttagaggaaaaatactcaatgttcgagaagcttctcataaacag atcatggaaaatgctgaaattaacaatatcatcaagattgtgggtcttcagtacaagaaa aactatgaagatgaagattcattgaagactcttcgttatgggaagataatgattatgaca gatcaggaccaagatggttcccatatcaaaggcttgctgattaattttatccatcacaac tggccctctcttctgcgacaccgttttctggaagaatttatcactcctattgtaaaggtg tctaaaaacaagcaagaaatggcattctatagccttcctgaatttgaagaatggaagagt tctacaccaaatcataaaaaatggaaagtcaagtactacaaaggtttgggcacgagcaca tcaaaagaggctaaggaatactttgcagatatgaaaagacatcgtattcaattcaaatat tccggtcctgaagatgatgccgccatcagcctggcctttagcaagaaacagatagatgat cgaaaggaatggttaactcatttcatggaggacagaaggcaacggaagttacttggcctt cctgaggattacttgtatgggcaaactaccacatatctgacatacaatgacttcataaac aaggaacttatcctgttctcaaactctgataacgagagatctattccatctatggtggat ggtttgaaaccaggtcaaagaaaggttttgtttacctgtttcaaacggaatgacaagcga gaggtgaaggttgctcagttagctgggtcagtggctgagatgtcctcttatcatcatggt gagatgtcactaatgatgaccattatcaatttggctcagaattttgtgggtagcaataat ctgaacctcttgcaacccattggtcagtttggtaccaggctgcatggtggtaaggattct gctagtcctcgatacatcttcacaatgctcagccctttggctcggttgttatttccacca aaagatgatcatacattaaagtttttatatgatgacaatcaacgtgttgaacctgaatgg tacattcctattatacccatggtgctgataaatggtgctgaaggaatcggtactgggtgg tcctgcaaaatcccgaactttgatattcgtgaagttgtaaataatatcaggcgtctgatg gatggagaagaacctttgccaatgcttccgagttacaagaacttcaggggtacgattgaa gagctggctccaaatcaatatgtgattagtggtgaagtggctattcttaattccacaacc attgaaatctcagaacttcccatcagaacatggacccagacatataaagaacaggttcta gaacccatgttgaatggcactgagaagacaccacctctcataaccgattatagggaatac catacagacaccactgtgaagtttgttgtgaagatgactgaagagaaattggcagaggca gagagagtgggactacacaaagtcttcaaactccaaactagtctcacatgcaactctatg gtgctttttgaccatgtaggatgtttaaagaaatatgacacagtgttggatattctaaga gacttctttgaactcaggcttaaatattatggattaagaaaagaatggctactaggaatg cttggtgctgaatctgctaaactgaacaatcaggctcgctttatcttagagaaaatagat ggcaaaataatcattgaaaataagccaaagaaggaattaattaaagttctgattcagagg ggttatgattctgatcctgtgaaggcttggaaagaagcccagcaaaaggtaccagatgaa gaagaaaatgaagagagtgacaatgaaaatgaagctgaaaagggtgactctgtaaaagat tctggaccaaccttcaactaccttcttgatatgcctctttggtatctcaccaaggaaaag aaggatgaactgtgcaagctgagaaatgaaaaagaacaagagctagaaacattaaagaga aagagtccatcagatttgtggaaagaagacctcgctgcttttattgaagagctggaggct gttgaaacaaaggaaaaacaagaagaacaaataggactccctgggaaaggggggaaagca aaggggaaaaaaatacagatggctgaagttttgccttctccatgtgggaaaagagtcatc ccccgagtgaccatagagatgaaagcagaggcagaaaagaaaattaaaaagaaaattaag agtgaaaacactgaagggagccctcaagagaatggtatggaactagaaggtctgaaacaa aggttggagaagaaacagaaaagagaaccaggtaccaagacaaagaagcaaactacgttg ccatttaaaccagtcaaaaaaggaaagaagagaaacccctggtctgattcagaatcagat atgagcagtaatgaaagtgactttgatgttcccccacgagagatggagccacggagagca gcaacaaaaaccaaatttacagtggatttggattcagatgatgatttctcagattttgat gaaaaaactcaagatgaggattttgtcccatcagatgttagcccagttaagaccaaaact tccccaccagtacctactaacaaagaactgaagccacagaagagtgccacatcagtaacg gaccttgatgctggtggtgccaaggacagtgtaccaccttctctagattctccggccgct gatttctcagctgaaactgaaatcataaaccctgtttctaaaaagaaggtagcggtgaag aagacagcagcaaaaagtcagtcttccacctccactgcaggtgccaaaaaaagggctgca ccaaaaggaaccaaaaaggagccaggcttgaattctgatgtctctcaaaagcctgatcct cccaaaaccaaaaatcgccgcaaaaggaagccatccacttctgatgattctgactctaat tttgagaaaatgatttctaagacagtcacaagcaagaaatccaagggggagagtgaggat ttccatctggacttagactcagctgtggctcctcgggccaaatctggacgggcaaagaaa cctataaagtacctcgaagaatcagatgaagatgatctgttctaa

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