KEGG   Lynx rufus (bobcat): 124517572
Entry
124517572         CDS       T08475                                 
Name
(RefSeq) rho-associated protein kinase 1 isoform X1
  KO
K04514  Rho-associated protein kinase 1 [EC:2.7.11.39]
Organism
lruf  Lynx rufus (bobcat)
Pathway
lruf04022  cGMP-PKG signaling pathway
lruf04024  cAMP signaling pathway
lruf04062  Chemokine signaling pathway
lruf04071  Sphingolipid signaling pathway
lruf04270  Vascular smooth muscle contraction
lruf04350  TGF-beta signaling pathway
lruf04360  Axon guidance
lruf04510  Focal adhesion
lruf04520  Adherens junction
lruf04530  Tight junction
lruf04611  Platelet activation
lruf04670  Leukocyte transendothelial migration
lruf04810  Regulation of actin cytoskeleton
lruf04921  Oxytocin signaling pathway
lruf05135  Yersinia infection
lruf05163  Human cytomegalovirus infection
lruf05200  Pathways in cancer
lruf05205  Proteoglycans in cancer
lruf05206  MicroRNAs in cancer
Brite
KEGG Orthology (KO) [BR:lruf00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04350 TGF-beta signaling pathway
    124517572
   04071 Sphingolipid signaling pathway
    124517572
   04024 cAMP signaling pathway
    124517572
   04022 cGMP-PKG signaling pathway
    124517572
 09140 Cellular Processes
  09144 Cellular community - eukaryotes
   04510 Focal adhesion
    124517572
   04520 Adherens junction
    124517572
   04530 Tight junction
    124517572
  09142 Cell motility
   04810 Regulation of actin cytoskeleton
    124517572
 09150 Organismal Systems
  09151 Immune system
   04611 Platelet activation
    124517572
   04670 Leukocyte transendothelial migration
    124517572
   04062 Chemokine signaling pathway
    124517572
  09152 Endocrine system
   04921 Oxytocin signaling pathway
    124517572
  09153 Circulatory system
   04270 Vascular smooth muscle contraction
    124517572
  09158 Development and regeneration
   04360 Axon guidance
    124517572
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    124517572
   05206 MicroRNAs in cancer
    124517572
   05205 Proteoglycans in cancer
    124517572
  09172 Infectious disease: viral
   05163 Human cytomegalovirus infection
    124517572
  09171 Infectious disease: bacterial
   05135 Yersinia infection
    124517572
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases [BR:lruf01001]
    124517572
  09182 Protein families: genetic information processing
   03036 Chromosome and associated proteins [BR:lruf03036]
    124517572
Enzymes [BR:lruf01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.11  Protein-serine/threonine kinases
    2.7.11.39  ROCK-subfamily protein kinase
     124517572
Protein kinases [BR:lruf01001]
 Serine/threonine kinases: AGC group
  DMPK family [OT]
   124517572
Chromosome and associated proteins [BR:lruf03036]
 Eukaryotic type
  Centrosome formation proteins
   Kinases and associated factors
    124517572
SSDB
Motif
Pfam: Pkinase PK_Tyr_Ser-Thr Rho_Binding PH C1_1 Cortex-I_coil Pkinase_C APH DUF1192
Other DBs
NCBI-GeneID: 124517572
NCBI-ProteinID: XP_046942874
LinkDB
Position
Unknown
AA seq 1355 aa
MSTGDSFETRFEKIDNLLRDPKSEVNSDCLLDGLDALVYDLDFPALRKNKNIDNFLSRYK
DTINKIRDLRMKAEDYEVVKVIGRGAFGEVQLVRHKSTRKVYAMKLLSKFEMIKRSDSAF
FWEERDIMAFANSPWVVQLFYAFQDDRYLYMVMEYMPGGDLVNLMSNYDVPEKWARFYTA
EVVLALDAIHSMGFIHRDVKPDNMLLDKSGHLKLADFGTCMKMNKEGMVRCDTAVGTPDY
ISPEVLKSQGGDGYYGRECDWWSVGVFLYEMLVGDTPFYADSLVGTYSKIMNHKNSLTFP
DDNDISKEAKNLICAFLTDREVRLGRNGVEEIKRHLFFKNDQWAWETLRDTVAPVVPDLS
SDIDTSNFDDLEEDKGDEETFPIPKAFVGNQLPFVGFTYYSNRRYLSSANPNDNRSSPNV
DKSLQENLQKTIYKLEEQLHNEMQLKDEMEQKCRTSNIKLDKIMKELDEEGNQRRNLEST
VSQIEKEKMLLQHRINEYQRKVEQENEKRRNVENEVSTLKDQLEDLKKVSQNSQLANEKL
TQLQKQLEEANDLLRTESDTAVRLRKSHTEMSKSISQLESLNRELQERNRILENSKTQMD
KDYYQLQAVLEAERRDRGHDSEMIGDLQARITSLQEEVKHLKHNLERVEGERKEAQDMLN
HSEKEKNNLEIDLNYKLKSLQQRLEQEVNEHKVTKARLTDKHQSIEEAKSVAMCEMEKKL
KEEREAREKAENRVVQIEKQCSMLDVDLKQSQQKLEHLTENKERMEDEVKNLSLQLEQES
NKRVLLQNELKTQAFEADNLKGLEKQMKQEINTLLEAKRLLEFELAQLTKQYRGNEGQMR
ELQDQLEAEQYFSTLYKTQVKELKEEIEEKNRENLKKIQELQNEKETLTTQLDLAETKAE
SEQLARGLLEEQYFELTQESKKAASRNRQEITDKDHTVSRLEETNSMLTKDLELLRKENE
ELTDKMRRTEEEYKLKKEEEINNLKATYEKNISTERTLKTQAVNKLAEIMNRKDFKIDRK
KANTQDLRKKEKENRKLQLELNQEREKFNQMVVKHQKELNDMQAQLVEECTHRNELQMQL
ASKESDIEQLRAKLLDLSDSTSVASFPSADETDGNLPESRIEGWLSIPNRGNIKRYGWKK
QYVVVSSKKILFYNDEQDKEQSNPSMVLDIDKLFHVRPVTQGDVYRAETEEIPKIFQILY
ANEGECRKDVEMEPVQQAEKTNFQNHKGHEFIPTLYHFPANCEACAKPLWHVFKPPPALE
CRRCHVKCHRDHLDKKEDLISPCKVSYDVTSARDMLLLACSQDEQKKWVTHLVKKIPKNP
PSGFVRASPRTLSTRSTANQSFRKVVKNTSAKTSS
NT seq 4068 nt   +upstreamnt  +downstreamnt
atgtcgactggggacagttttgagactcggtttgaaaaaatcgacaacctgctgcgggat
cccaaatcggaagtgaattcggattgtttgctggatggattggatgctttggtatatgat
ttggattttcctgccttaagaaaaaacaaaaatattgacaactttttaagcagatataaa
gacacaataaataaaattagagatttacgaatgaaagctgaagattatgaagtagtgaag
gtgattggtagaggtgcatttggagaagttcaattggtaaggcataaatctaccaggaag
gtatatgctatgaagcttcttagtaaatttgaaatgattaagagatctgattctgctttt
ttctgggaagaaagagacatcatggcttttgctaacagtccttgggtcgttcagcttttt
tatgcattccaagatgatcgttatctctacatggtgatggagtacatgcctggtggagat
cttgtaaacttaatgagcaactatgatgtgcctgaaaaatgggcacgattctacactgca
gaagtagttcttgcattggatgcaatccattccatgggtttcattcatagagatgtgaag
cctgataacatgctgctggataaatctggacatttgaagttagcagattttggtacttgt
atgaagatgaataaggaaggtatggtacgatgtgatacagcagttggaacacccgattac
atttcccctgaagtattaaaatctcaaggtggtgatggttattatggacgagaatgtgac
tggtggtcagttggggtatttttatatgaaatgcttgtaggtgatacacctttttatgca
gattctctggttggaacttatagtaagattatgaaccataaaaattcacttactttccct
gatgataatgatatatcaaaagaagcaaaaaatcttatttgtgccttccttactgacaga
gaggtgagattaggacgaaatggtgtggaagaaatcaaacgacatcttttcttcaaaaat
gatcagtgggcttgggaaacactcagagacactgtagcgccagttgtacctgatttaagt
agcgacattgatacaagtaattttgatgacttggaagaagataaaggagatgaagaaaca
ttccctatacctaaagcttttgttggcaatcagttaccttttgtaggatttacgtattat
agcaatcgtagatacttatcttcagcaaatcctaatgataaccgaagtagccccaatgtg
gataaaagcttgcaggaaaatttgcaaaaaacaatttataagctggaagaacaactgcat
aatgaaatgcaattaaaagatgaaatggagcagaagtgcagaacttcaaacataaaacta
gacaagataatgaaagaattggatgaagagggaaatcaaagaagaaacctagagtctaca
gtgtctcagattgagaaagagaaaatgttgctacagcatagaattaatgagtaccaaaga
aaagtagaacaggaaaatgagaagaggagaaatgtagaaaatgaagtttctacattaaag
gatcagttagaagacttaaagaaagtaagtcagaattcacagcttgccaatgagaagctg
acacagttacaaaagcagctagaagaagccaatgacttacttaggacagaatcagacaca
gctgtaagattaaggaagagtcacacagagatgagtaagtcaattagtcagctagagtcc
ttaaacagagaattgcaggagagaaatagaattttagagaattccaagacacaaatggac
aaggactattaccagctgcaagctgtgttagaagctgaacgaagagacagaggtcatgat
tctgagatgattggagaccttcaagctcgaattacatctttacaagaagaggtaaagcat
ctcaagcataatcttgaaagagtggaaggagaaagaaaagaagctcaagacatgcttaat
cactcagaaaaggaaaagaataatttagagatagatttaaactataagcttaaatcatta
caacaaaggttagaacaagaggtaaatgaacataaagtaaccaaagctcgtttaactgac
aaacatcagtctattgaagaggcaaagtctgttgcaatgtgtgaaatggaaaagaagctg
aaggaagagagagaagctcgagagaaggctgaaaatagagttgttcagattgagaaacag
tgttcaatgctagatgttgatctgaaacaatctcagcagaagcttgagcatttgactgaa
aataaagaaaggatggaggatgaagttaagaatctatccctgcaactggagcaggaatca
aataagcgagtattgttacagaatgaattgaagactcaagcatttgaagcggacaattta
aaaggtctagaaaagcagatgaaacaggaaataaatactttattggaagcaaagagatta
ttagaatttgagttagctcagcttacaaaacagtatagaggaaatgaaggacagatgcgg
gagctacaagatcagcttgaagcagagcaatatttttcgacactttataaaacccaggta
aaggaacttaaggaagaaattgaagaaaaaaacagagaaaatttaaagaaaatacaggaa
ctacaaaatgaaaaagaaactcttactactcagttggatctagcagaaacaaaagccgag
tctgagcagttggctcgagggcttctggaagaacagtattttgaattgacccaagaaagc
aagaaagctgcctcaagaaatagacaggagattacagataaagatcacactgttagtcgg
cttgaagaaacaaacagcatgctaaccaaagatcttgaattattaagaaaagaaaatgaa
gagctaactgataaaatgaggaggacagaggaagaatataaactgaagaaagaggaagag
atcaataatcttaaggctacctatgaaaagaatatcagtacagaaagaacccttaaaaca
caggctgttaacaagttggcagaaataatgaatcggaaagattttaaaattgatagaaag
aaagctaatacacaggatttgagaaagaaagaaaaggaaaatcgaaagcttcaactggaa
ctcaaccaagaaagagagaaattcaaccagatggtggtgaaacatcagaaggaactgaat
gacatgcaagcgcaattggtagaagaatgtacacataggaatgagcttcagatgcaattg
gctagcaaagagagtgatattgagcaattgcgtgctaaacttttggacctttcggattct
acaagtgttgctagttttcctagtgctgatgaaactgatggaaaccttccagagtcaaga
attgaaggctggctttcaataccaaacagaggaaatatcaaacgatatggctggaagaaa
cagtatgttgtagtaagcagcaaaaaaattttgttctataacgatgagcaagataaggaa
caatccaatccatccatggtattggacatagataaattgtttcatgttcgacctgtaacc
caaggagatgtttacagagctgaaactgaagaaattcctaaaatattccagatactatat
gcaaatgaaggtgaatgtagaaaagatgtagagatggaaccagtacagcaagctgaaaag
actaattttcaaaaccacaaaggccatgagttcattcctacactctaccactttcctgcc
aactgtgaggcctgtgccaaacctctctggcatgtttttaagccacctcctgccctagaa
tgtcgaagatgccatgttaagtgccacagagatcacttagataagaaagaggacttaatt
tctccatgtaaagtcagttatgatgtaacatcagcaagagatatgctgctgttagcatgt
tctcaggatgaacaaaaaaaatgggtaacacatttggtgaagaagatccctaagaatcca
ccatctggttttgttcgtgcatcccctcgaacactttctacaagatccactgcaaatcag
tctttccgaaaagtcgtcaaaaatacatcagcaaaaactagcagttaa

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