Lynx rufus (bobcat): 124518489 Help Entry 124518489         CDS       T08475                                  Name (RefSeq) nitric oxide synthase, brain   KO K13240   nitric-oxide synthase, brain [EC:1.14.13.39] Organism lruf  Lynx rufus (bobcat) Pathway lruf00220   Arginine biosynthesis lruf00330   Arginine and proline metabolism lruf01100   Metabolic pathways lruf04020   Calcium signaling pathway lruf04081   Hormone signaling lruf04145   Phagosome lruf04371   Apelin signaling pathway lruf04713   Circadian entrainment lruf04730   Long-term depression lruf04926   Relaxin signaling pathway lruf04970   Salivary secretion lruf05010   Alzheimer disease lruf05014   Amyotrophic lateral sclerosis lruf05022   Pathways of neurodegeneration - multiple diseases lruf05410   Hypertrophic cardiomyopathy lruf05412   Arrhythmogenic right ventricular cardiomyopathy lruf05414   Dilated cardiomyopathy lruf05416   Viral myocarditis Brite KEGG Orthology (KO) [BR:lruf00001]  09100 Metabolism   09105 Amino acid metabolism    00220 Arginine biosynthesis     124518489    00330 Arginine and proline metabolism     124518489  09130 Environmental Information Processing   09132 Signal transduction    04371 Apelin signaling pathway     124518489    04020 Calcium signaling pathway     124518489   09133 Signaling molecules and interaction    04081 Hormone signaling     124518489  09140 Cellular Processes   09141 Transport and catabolism    04145 Phagosome     124518489  09150 Organismal Systems   09152 Endocrine system    04926 Relaxin signaling pathway     124518489   09154 Digestive system    04970 Salivary secretion     124518489   09156 Nervous system    04730 Long-term depression     124518489   09159 Environmental adaptation    04713 Circadian entrainment     124518489  09160 Human Diseases   09164 Neurodegenerative disease    05010 Alzheimer disease     124518489    05014 Amyotrophic lateral sclerosis     124518489    05022 Pathways of neurodegeneration - multiple diseases     124518489   09166 Cardiovascular disease    05410 Hypertrophic cardiomyopathy     124518489    05412 Arrhythmogenic right ventricular cardiomyopathy     124518489    05414 Dilated cardiomyopathy     124518489    05416 Viral myocarditis     124518489 Enzymes [BR:lruf01000]  1. Oxidoreductases   1.14  Acting on paired donors, with incorporation or reduction of molecular oxygen    1.14.13  With NADH or NADPH as one donor, and incorporation of one atom of oxygen into the other donor     1.14.13.39  nitric-oxide synthase (NADPH)      124518489 BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  NO_synthase FAD_binding_1 Flavodoxin_1 NAD_binding_1 PDZ PDZ_6 PDZ_2 Motif Other DBs NCBI-GeneID:  124518489 NCBI-ProteinID:  XP_046944457 LinkDB All DBs Position Unknown AA seq 1459 aa AA seqDB search MENQVFSVQQIQPNVISVRLFKRKVGGLGFLVKERVSKPPVIISDLIRGGAAEQSGLIQA GDIILAVNGQPLVDLSYDSALEVLRGIASETHVVLILRGPEGFTTHLETTFTGDGTPKTI RVTRPLAAPTTAVDLSHQSSASREHSPAVDRATGPGNGPQHAQDGGQEAGSLPHTKSRAP GPPGQDSAKKSIQGSQHSDLLKEIEPVLSLLTSGSKGINGGGPSKAETKDAEVQVDRGMD GKSHKPLPLGVENDRVFSDLWGKGHVPVVLNNPYSEKEQPPASGKQSPTKNGSPSKCPRF LKVKNWETDVVLTDTLHLKSTLEMGCTEHICMGSIMLPSQQIRRPEDVRTKEQLFPLAKE FIDQYYSSIKRFGSKAHTERLEEVNKEIETTGTYQLKDTELIYGAKHAWRNASRCVGRIQ WSKLQVFDARDCTTAHGMFNYICNHIKYATNKGNLRSAITIFPQRTDGKHDFRVWNSQLI RYAGYKQPDGSILGDPANVEFTEICAQQGWKPPRGRFDILPLLLQANGNDPELFQIPPEL VLEVPIRHPRFEWFKDLGLKWYGLPAVSNMLLEIGGLEFTACPFSGWYMGTEIGVRDYCD NSRYNILEEVAKNMNLDMRKTSSLWKDQALVEINIAVLYSFQSDKVTIVDHHSATESFIK HMENEYRCRGGCPADWVWIVPPMSGSVTPVFHQEMLNYRLTPSFEYQPEPWNTHVWKGTN GTPTKRRAIGFKKLAEAVKFSAKLMGQAMAKRVKATILYATETGKSQAYAKTLCEIFKHA FDAKVMSMEEYDIVHLEHETLVLVVTSTFGNGDPPENGEKFGCALMEMRHPNSVQEERKY PEPLRFFPRKGPPLPQGDTEVHGLAAARDSQQRSYKVRFNSVSSYSDSHKSSGDGPDLRD NFESAGPLANVRFSVFGLGSRAYPHFCAFGHAVDTLLEELGGERILKMREGDELCGQEEA FRTWAKKVFKAACDVFCVGDDVNIEKANNSLISNDRSWKRNKFRLTYVAEAPELTQGLSN VHKKRVSAARLLSRQNLQSPKSSRSTIFVRLHTNGNQELQYQPGDHLGVFPGNREDLVNA LMERLEDAPPVNQLVKVELLVERNTALGVISNWTDEHRLPPCTIFQAFKYYLDITTPPTP LQLQQFASLATSEKEKQRLLVLSKGLQEYEEWKWGKNPTIVEVLEEFPSIQMPTTLLLTQ LSLLQPRYYSISSSPDMYPDEVHLTVAVVSYHTRDGEGPIHHGVCSSWLNRIPADEVVPC FVRGAPSFHLPRNPQVPCILIGPGTGIAPFRSFWQQRQFDIQHKGMSPCPMVLVFGCRQS KIDHIYREETLQAKNKGVFRELYTAYSREPDKPKKYVQDILQEHLAEPVYRALKEQGGHI YVCGDVTMAADVLKAIQRIMTQQGKLSAEDAGVFISRLRDDNRYHEDIFGVTLRTYEVTN RLRSESIAFIEESKKDTDE NT seq 4380 nt NT seq  +upstreamnt  +downstreamnt atggagaatcaggtgttcagcgttcagcagatccaacccaacgtcatctccgtccgcctc ttcaagcgcaaggtggggggcctggggttcctggtgaaggagcgggtgagcaagccgccc gtgatcatctccgacctgattcgggggggtgccgcggagcagagcggcctcatccaggcc ggtgacatcatccttgcagtcaacggccagcccctggtggacctgagctatgacagcgcc ctggaggtgctcaggggcatcgcctctgagacccacgtggtcctcattctgaggggcccc gagggcttcaccactcacctggagaccaccttcaccggggacgggacccccaagaccatc cgcgtgacacggcctctggctgcccccaccaccgctgtcgatctgtctcaccagtcatcg gccagcagagagcactcaccggcagtggacagggccacgggtcctggcaatgggccgcag cacgcccaagacggtgggcaggaagccggctctctcccccataccaagagccgggctccc gggcccccgggccaggactctgccaagaagagtatccagggcagccagcacagtgatttg ctcaaagagatagaacctgtactgagccttctcaccagtgggagcaaagggatcaatggc gggggaccttccaaggcagagacgaaggatgcagaagtccaggtggacagaggtatggat ggcaagtcacacaagccactgcccctgggcgtggagaatgaccgagtcttcagtgacctg tgggggaagggccacgtgcctgtcgtcctcaacaacccgtattcagagaaggagcagccc cctgcctcgggaaaacagtctcctacaaagaacggcagcccctccaagtgcccccgcttc ctcaaggtcaagaactgggagaccgacgtggtcctcactgacacccttcaccttaagagc acattggaaatgggctgcaccgagcacatctgtatgggctccatcatgctcccctctcag cagatacgaaggcctgaagacgtccgcacaaaagaacagctcttccctctcgccaaagag ttcattgaccagtactactcatcaattaaaaggtttggctccaaagcccacacggagagg ctggaagaggtgaacaaagagatcgaaaccaccggcacctaccagctcaaagacacggag ctcatctacggggccaagcacgcctggcggaacgcctcccgctgcgtgggtaggatccag tggtccaagctgcaggtgttcgatgcccgcgactgcaccacggctcacgggatgttcaac tacatctgcaaccacatcaagtatgccaccaacaaggggaacctcagatccgccatcacc atattcccccagaggacggacggcaagcacgatttccgagtctggaactctcagctcatc cgctatgccggctacaagcagcctgatggctccatcctgggggacccagccaatgtggaa ttcacagagatctgtgcgcagcagggctggaaacccccaagaggccgcttcgatatcctg ccactcctgctccaggccaacggcaacgatcccgagctcttccagatccccccagagctg gtgttggaagtgcccatcaggcaccccaggtttgagtggttcaaggatctgggcctgaag tggtatggcctccccgctgtgtccaacatgctgctggagattggcggcctggagttcacc gcctgtcccttcagcggctggtacatgggcacagagattggcgtccgcgactattgtgac aactctcgatacaacatcctggaggaagtggccaagaacatgaacttggacatgaggaag acgtcctccctgtggaaggaccaagcactggtggaaatcaacattgctgttctctacagc ttccagagtgacaaagtgaccatcgttgaccaccactctgccaccgagtccttcatcaag cacatggagaatgaataccgctgccgggggggctgccccgccgactgggtgtggattgtg ccccccatgtctggcagtgtcacccctgtcttccaccaggagatgctcaactaccgactc accccgtccttcgaataccagcctgagccttggaacacccacgtctggaaaggcaccaat ggaacccccacaaagcggcgagccatcggcttcaagaagctggcagaagccgtcaagttc tcagccaagcttatggggcaggcaatggccaagagggtcaaggcgaccatcctttatgcc acagagacgggcaagtcgcaggcctatgctaaaaccttgtgtgagatcttcaaacatgcc tttgatgccaaggtgatgtccatggaagaatatgacattgtacacctggaacatgaaact ctggtcctagtggttaccagcacttttggcaatggcgaccccccagagaatggggagaaa ttcggctgtgctttgatggaaatgaggcaccccaactccgtgcaggaggaaaggaagtac ccggaacccttgcgtttctttccccgtaaagggcctcccctcccccaaggtgacacagaa gtccatggtctggctgcagcccgtgacagccagcagaggagctacaaggtccgattcaat agtgtttcctcgtattctgactcccataaatcatcaggcgacgggccagacctcagagac aactttgagagtgctggacccctggccaacgtgaggttctccgtatttggccttggctcc cgggcttaccctcatttctgcgcctttggacatgccgtggacaccctcctggaggaactg ggaggagagaggatcctgaagatgagggagggagacgagctctgtgggcaggaagaggct ttcaggacctgggccaagaaggtcttcaaggcagcctgcgatgtgttctgcgtgggagat gacgtcaacattgagaaggcaaacaactccctcatcagcaacgaccgcagctggaaaaga aacaagttccgcctcacctacgtggccgaagctccggaacttacacaaggtctatccaat gtccacaaaaagcgggtctcggccgctcgactcctcagccgccaaaaccttcagagccct aaatccagccgatcaacgatcttcgtgcgtctccacaccaatgggaatcaggagctgcag taccagcctggggaccacctgggcgtcttccctggcaaccgcgaggacctcgtgaacgcc ctgatggagcggctggaagatgctcccccagtcaaccagctggtgaaggtggaactgctg gtggagaggaacacggctttgggcgtcatcagtaactggacagatgagcaccgcctcccg ccctgcaccatcttccaggccttcaagtactacctggacatcaccacgccgcccacgcca ctgcagctgcagcagtttgcgtccctggccaccagcgagaaagagaagcagcgactgctg gtcctcagcaagggcttgcaggagtacgaggaatggaaatggggcaagaaccccaccatc gtggaggtgctggaagagttcccgtccatccagatgcccaccaccctgctcctgacccag ctgtccctgctgcagcctcgatactattccatcagttcttccccagacatgtaccctgac gaggtgcacctcaccgtggccgttgtctcctaccacacccgagatggagaaggaccaatt caccacggcgtgtgctcctcctggctcaaccggataccggctgacgaagtggtcccctgt ttcgtgagaggagcacccagcttccacctgccccgaaatccccaagtgccctgtatcctc atcggcccaggcactggcattgcccctttccgaagcttctggcaacagcgacaatttgat atccagcacaaaggaatgagcccctgccccatggtcctggtgtttgggtgccggcaatcc aagatagaccacatctacagggaggaaaccctacaggccaagaacaagggcgtcttcaga gaactctacacggcctactcgcgggagccagacaaaccaaagaagtacgttcaggacatc ctgcaggagcacttggcagaacccgtgtaccgagccctgaaggagcaagggggccacatt tacgtctgcggggacgtcaccatggccgccgatgtcctcaaagccatccagcgcatcatg acccagcaagggaaactctcagcggaggatgccggcgtgttcatcagcaggctgagggat gacaaccggtaccatgaggatattttcggggtcaccctgcgaacatatgaagtgaccaac cgccttagatctgaatccattgccttcattgaggagagcaaaaaagacactgatgagtaa

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