KEGG   Lynx rufus (bobcat): 124519495
Entry
124519495         CDS       T08475                                 
Name
(RefSeq) dual specificity mitogen-activated protein kinase kinase 4
  KO
K04430  mitogen-activated protein kinase kinase 4 [EC:2.7.12.2]
Organism
lruf  Lynx rufus (bobcat)
Pathway
lruf04010  MAPK signaling pathway
lruf04012  ErbB signaling pathway
lruf04620  Toll-like receptor signaling pathway
lruf04664  Fc epsilon RI signaling pathway
lruf04668  TNF signaling pathway
lruf04912  GnRH signaling pathway
lruf04926  Relaxin signaling pathway
lruf04935  Growth hormone synthesis, secretion and action
lruf04936  Alcoholic liver disease
lruf05132  Salmonella infection
lruf05135  Yersinia infection
lruf05142  Chagas disease
lruf05161  Hepatitis B
lruf05166  Human T-cell leukemia virus 1 infection
lruf05167  Kaposi sarcoma-associated herpesvirus infection
lruf05169  Epstein-Barr virus infection
lruf05208  Chemical carcinogenesis - reactive oxygen species
lruf05417  Lipid and atherosclerosis
lruf05418  Fluid shear stress and atherosclerosis
Brite
KEGG Orthology (KO) [BR:lruf00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    124519495
   04012 ErbB signaling pathway
    124519495
   04668 TNF signaling pathway
    124519495
 09150 Organismal Systems
  09151 Immune system
   04620 Toll-like receptor signaling pathway
    124519495
   04664 Fc epsilon RI signaling pathway
    124519495
  09152 Endocrine system
   04912 GnRH signaling pathway
    124519495
   04926 Relaxin signaling pathway
    124519495
   04935 Growth hormone synthesis, secretion and action
    124519495
 09160 Human Diseases
  09161 Cancer: overview
   05208 Chemical carcinogenesis - reactive oxygen species
    124519495
  09172 Infectious disease: viral
   05166 Human T-cell leukemia virus 1 infection
    124519495
   05161 Hepatitis B
    124519495
   05167 Kaposi sarcoma-associated herpesvirus infection
    124519495
   05169 Epstein-Barr virus infection
    124519495
  09171 Infectious disease: bacterial
   05132 Salmonella infection
    124519495
   05135 Yersinia infection
    124519495
  09174 Infectious disease: parasitic
   05142 Chagas disease
    124519495
  09166 Cardiovascular disease
   05417 Lipid and atherosclerosis
    124519495
   05418 Fluid shear stress and atherosclerosis
    124519495
  09167 Endocrine and metabolic disease
   04936 Alcoholic liver disease
    124519495
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases [BR:lruf01001]
    124519495
Enzymes [BR:lruf01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.12  Dual-specificity kinases (those acting on Ser/Thr and Tyr residues)
    2.7.12.2  mitogen-activated protein kinase kinase
     124519495
Protein kinases [BR:lruf01001]
 Serine/threonine kinases: STE group
  STE7 family
   124519495
SSDB
Motif
Pfam: Pkinase PK_Tyr_Ser-Thr Kinase-like ABC1 Seadorna_VP7 Pkinase_fungal Haspin_kinase Choline_kinase APH
Other DBs
NCBI-GeneID: 124519495
NCBI-ProteinID: XP_046945737
LinkDB
Position
Unknown
AA seq 400 aa
MAAPSPSGGGGGSGGGSGSGTPGPVGPPAPGHPAVSSMQGKRKALKLNFANPPFKSTARF
TLNPNPTGVQNPHIERLRTHSIESSGKLKISPEQHWDFTAEDLKDLGEIGRGAYGSVNKM
VHKPSGQIMAVKRIRSTVDEKEQKQLLMDLDVVMRSSDCPYIVQFYGALFREGDCWICME
LMSTSFDKFYKYVYSVLDDVIPEEILGKITLATVKALNHLKENLKIIHRDIKPSNILLDR
SGNIKLCDFGISGQLVDSIAKTRDAGCRPYMAPERIDPSASRQGYDVRSDVWSLGITLYE
LATGRFPYPKWNSVFDQLTQVVKGDPPQLSNSEEREFSPSFINFVNLCLTKDESKRPKYK
ELLKHPFILMYEERTVEVACYVCKILDQMPATPSSPMYVD
NT seq 1203 nt   +upstreamnt  +downstreamnt
atggcggctccgagcccgagcggcggcggcggcggctccgggggcggcagcggcagcggc
accccgggccccgtggggcccccggcgccgggccacccggccgtcagcagcatgcagggt
aaacgcaaagcactgaagttgaattttgcaaatccacctttcaaatctacagcaaggttt
actctgaatcccaatcctacaggagttcaaaacccacacatagagaggctgagaacacac
agcatcgaatcgtcgggaaaactgaagatctctcctgagcagcactgggatttcaccgcg
gaggacttgaaggaccttggagaaatcggacgaggagcttacggttccgtcaacaaaatg
gtccacaaaccaagtgggcagataatggcagttaaaagaattcggtcaacagtggatgaa
aaagaacaaaaacaacttcttatggatttggatgtagtaatgcgcagtagtgactgcccg
tacattgttcagttttatggtgcactcttcagagagggtgactgttggatctgtatggaa
ctcatgtctacctcgtttgataagttttacaaatatgtatatagtgtattagatgatgtt
attccagaagaaattttaggcaaaatcactttagcaactgtgaaagcactaaaccactta
aaagaaaacttgaaaatcattcacagagatatcaaaccttccaatattcttctggacagg
agcgggaatattaagctctgtgactttggcatcagtggacagctggtggactccattgcc
aagacaagagatgccgggtgtaggccatacatggcacctgaaagaatagacccaagtgca
tctcgacaaggatatgatgtccgctctgatgtctggagtttggggatcacattgtacgag
ttagccacaggccgatttccttacccaaagtggaatagtgtattcgatcaactaacacaa
gtcgtgaaaggagaccctccacagctgagtaactcagaggaaagggagttctcccccagt
ttcatcaactttgtcaacttgtgccttacgaaggatgaatccaaaaggccaaagtataaa
gaacttctgaaacatccctttattttgatgtatgaagaacgtaccgtagaggtcgcatgc
tacgtttgtaaaatcctggatcaaatgccagccactcccagctcccccatgtacgtcgac
tga

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