Lynx rufus (bobcat): 124521338
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Entry
124521338 CDS
T08475
Name
(RefSeq) pyruvate dehydrogenase E1 component subunit alpha, somatic form, mitochondrial-like isoform X1
KO
K00161
pyruvate dehydrogenase E1 component subunit alpha [EC:
1.2.4.1
]
Organism
lruf
Lynx rufus (bobcat)
Pathway
lruf00010
Glycolysis / Gluconeogenesis
lruf00020
Citrate cycle (TCA cycle)
lruf00620
Pyruvate metabolism
lruf00785
Lipoic acid metabolism
lruf01100
Metabolic pathways
lruf01200
Carbon metabolism
lruf01210
2-Oxocarboxylic acid metabolism
lruf04066
HIF-1 signaling pathway
lruf04922
Glucagon signaling pathway
lruf05230
Central carbon metabolism in cancer
lruf05415
Diabetic cardiomyopathy
Module
lruf_M00307
Pyruvate oxidation, pyruvate => acetyl-CoA
Brite
KEGG Orthology (KO) [BR:
lruf00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00010 Glycolysis / Gluconeogenesis
124521338
00020 Citrate cycle (TCA cycle)
124521338
00620 Pyruvate metabolism
124521338
09108 Metabolism of cofactors and vitamins
00785 Lipoic acid metabolism
124521338
09130 Environmental Information Processing
09132 Signal transduction
04066 HIF-1 signaling pathway
124521338
09150 Organismal Systems
09152 Endocrine system
04922 Glucagon signaling pathway
124521338
09160 Human Diseases
09161 Cancer: overview
05230 Central carbon metabolism in cancer
124521338
09166 Cardiovascular disease
05415 Diabetic cardiomyopathy
124521338
Enzymes [BR:
lruf01000
]
1. Oxidoreductases
1.2 Acting on the aldehyde or oxo group of donors
1.2.4 With a disulfide as acceptor
1.2.4.1 pyruvate dehydrogenase (acetyl-transferring)
124521338
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GFIT
Motif
Pfam:
E1_dh
TPP_enzyme_C
DXP_synthase_N
Chal_sti_synt_N
Motif
Other DBs
NCBI-GeneID:
124521338
NCBI-ProteinID:
XP_046948394
LinkDB
All DBs
Position
Unknown
AA seq
391 aa
AA seq
DB search
MRKMLAAAVFRVLSGVTQKPASRVLVASCNYSNDAMFAIKKCDLYRLEEGPPVTTVLTRE
DGLRYYRMMQTVRRMELKADQLYKQKFIRGFCHLCDGQEACSVGLEAGINPTDHVITSYR
AHGLCYTRGLSVRSILAELTGRRGGCAKGKGGSMHMYVKNFYGGNGIVGAQGPLGAGIAL
ACKYKGNKEVCLALYGDGAANQGQIAEAHNMAALWKLPCVFICENNLYGMGTPVERASAS
TDYYKRGNFIPGLRVDGMDVLGVREATKFVADYCRSGKGPIVMELQTYRYHGHSMSDPGI
SYRTREEVQNVRRESDPIMLLKDRMVNSKLATVEELKDIDVEVRKEVEDAAQFAMTDPEP
PLEELAHHIYCNTPAFEVRGANQWIKFKSLS
NT seq
1176 nt
NT seq
+upstream
nt +downstream
nt
atgaggaagatgctcgctgccgctgtcttccgcgtgttgtccggggtcacgcagaagccc
gctagcagagtgctggtggcatcctgtaactattcaaatgatgcgatgtttgcaattaag
aaatgtgatctttatcgcttagaagagggtccccctgtcacaacagtgctcacccgggag
gatgggctcagatactacaggatgatgcagactgttcgccgaatggagctgaaggcagat
cagctgtataaacaaaagtttatccgtggcttctgtcacttgtgcgatggtcaggaagct
tgttctgtgggcctggaggccgggataaatcccaccgaccatgtcatcacatcctatcgg
gctcatggcttgtgctatactcgtggactctctgtccgatcaattcttgcagagctgaca
ggacgaaggggaggctgtgctaaaggaaaaggaggatcgatgcatatgtatgtcaagaat
ttctatgggggcaatggcattgttggcgcacaggggcccctgggagctggtattgctctg
gcctgtaaatacaagggaaacaaggaggtctgtttggctctttatggggatggtgctgcg
aatcagggtcagatagccgaagctcacaatatggcagctttgtggaaattaccctgtgtt
ttcatctgtgagaataacctctatggaatgggaacccctgttgagagagcatcagccagc
actgattactataagagaggaaattttatccctggactgagggtagacggaatggatgtt
ctaggtgttcgggaggcaactaagtttgtagctgactactgtagatctggaaaggggccc
atagtgatggagctgcagacctaccggtatcatggacacagtatgagtgaccctgggatc
agttatcgtacccgagaagaagttcagaatgtgagaagggagagcgatcctattatgctt
ctcaaagacagaatggtaaacagtaagcttgccactgttgaggaactaaaggatattgat
gttgaagtgaggaaagaagttgaggatgcagcccagtttgctatgactgatcctgaacca
cctttggaagaattagctcatcacatctactgcaatactccagcttttgaagttcgtggt
gcaaaccagtggatcaagttcaagtccctcagttaa
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