Lynx rufus (bobcat): 124522605
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Entry
124522605 CDS
T08475
Name
(RefSeq) huntingtin
KO
K04533
huntingtin
Organism
lruf
Lynx rufus (bobcat)
Pathway
lruf05016
Huntington disease
lruf05022
Pathways of neurodegeneration - multiple diseases
Brite
KEGG Orthology (KO) [BR:
lruf00001
]
09160 Human Diseases
09164 Neurodegenerative disease
05016 Huntington disease
124522605
05022 Pathways of neurodegeneration - multiple diseases
124522605
09180 Brite Hierarchies
09182 Protein families: genetic information processing
03019 Messenger RNA biogenesis [BR:
lruf03019
]
124522605
04131 Membrane trafficking [BR:
lruf04131
]
124522605
03029 Mitochondrial biogenesis [BR:
lruf03029
]
124522605
Messenger RNA biogenesis [BR:
lruf03019
]
Eukaryotic type
mRNA surveillance and transport factors
mRNA cycle factors
Common to processing body (P body) and stress granule
124522605
Membrane trafficking [BR:
lruf04131
]
Endocytosis
Rab GTPases and associated proteins
Rab associated proteins
124522605
Mitochondrial biogenesis [BR:
lruf03029
]
Mitochondrial quality control factors
Regulator of mitochondrial biogenesis
Other regulator of mitochondrial biogenesis
124522605
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
Htt_C-HEAT
Htt_N-HEAT
Htt_bridge
Htt_N-HEAT_1
HEAT
HEAT_2
HEAT_EF3_N
Rad26-like_helical_rpts
Motif
Other DBs
NCBI-GeneID:
124522605
NCBI-ProteinID:
XP_046950102
LinkDB
All DBs
Position
Unknown
AA seq
3137 aa
AA seq
DB search
MATLEKLMKAFESLKSFQQQQQQQQQQQQQQPQPPPPPPQPPQPLPQAQPPLPQPQPPPP
PPPPPPPGPAVAEEPLHRPKKELSATKKDRVNHCLTICENIVAQSLRNSPEFQKLLGIAM
ELFLLCSDDAESDVRMVADECLNRVIKALMDSNLPRLQLELYKEIKKNGAPRSLRAALWR
FAELAHLVRPQKCRPYLVNLLPCLTRISKRPEESVQETLAAAVPKIMASFGNFANDNEIK
VLLKAFIANLKSSSPTIRRTAAGSAVTICQHSRRTQYFYSWLLNVLLGLLVPVEDEHSTL
LILGVLLTLRYLVPLLQQQVKDTSLKGSFGVTRKEMEVCPSTEQLIQVYELTLHYTQHQD
HNAVTGALELLQQLFRTPPPELLQALTAPGGGQRSGVQYGPGGRSRSGSIAELLAGGGSS
CSPVLSRKQKGKVLFGDAAALEDDSESRSEGSSPAFAASVKGEIGGELAASSGVSTPGSA
GSTADSVGHDIITEQPRSQHTLQPDSVDLTGCDLASAATDGDEEDILSHSSSQISAVPSD
PAIDLNDGTQASSPVSDSSQTTTEGPDSAVTPSDSSEIVLDGADSQYSGMQIGQPQDEDE
EAAGILPEEDVDAFRNSAAALQQAHLLKSMGHSRRPSDSSVDTFVSRDEAAEAGDQENKP
CRIKGDIGQSTDDDSVPLVHCVRLLSASFLLTGEKNVLVPDRDVRVSVKALALSCVGAAV
ALHPESFFSKLYKVPLDSVEYPEEPYVSDILNYIDHGDPQVRGATAVLCGTLISSTLSRS
RFQVGDWMGTVRALTGNTFSLEDCIPLLRKTLKDESSVTCKLACTAVRHCVMSLCSSSSS
ELGLQLITDVLSLRDSSYWLVRTELLETLAEIDFRLVSFLEAKAENLHRGAHHYTGLLKL
QDRVLHDVVIYLLGDEDPRVRHVAAAALMRLVPKLFYKCDQGQADPVVAVARDQSSVYLK
LLMHETQPPSHFSVSTITRIYRGYNLLPSMTDVTVENNLSRVIAAVSHELVTSTTRALTF
GCCEALCLLSTAFPVCVWSLGWHCGAPPLSVSGESRKSCTVGMATVILTLLSSAWFPLDL
AAHQDALVLAGNLLAASAPRSLRSSWTSEEEANPAAAKQEEVWPALGDRTLVPMVEQLFS
HLLKVINICAHVLDDVAPGPAIKAALPSLTNPPSLSPIRRKGKEKEPGEQASVPLSPKKG
SEASPASRQSDASGPVTANKSSSLGSFYHLPSYLKLHDVLKATHANYKVTLDLQNSAEKF
GGFLRSALDVLSQILELATLQDIGKCVEEILGYLKSCFSREPMMATVCVQQLLKTLFGTN
LASQFDGLSSNPSKSQGRAQRLGSSSVRPGLYHYCFMAPYTHFTQALADASLRNMVQAEQ
DHDASGWFDVLQKVSTQLKTNLTSTTKNRADKNAIHNHIRLFEPLVIKALKQYTTTTSVQ
LQRQVLDLLAQLVQLRVNYCLLDSDQVFIGFVLKQFEYIEVGQFRESEAIIPNIFFFLVL
LSYERYHSKQIIGIPKIIQLCDGIMASGRKAVTHAIPALQPIVHDLFVLRGANKADAGKE
LETQKEVVVSMLLRLIQYHQVLEMFILVLQQCHRESEDKWKRLSRQIADVILPMLAKQQM
HIDSHEALGVLNTLFEILAPSSLRPVDMLLRSMFVTPDTMAPVSTVQLWISGILAILRVL
ISQSTEDIVLSRIQELSFSPYLISCPIINRLREGDSTSTPEEHSEGRQMKSLPEETFSRF
LLQLVGILLEDIVTKQLKVEMSEQQHTFYCQELGTLLMCLIHIFKSGMFRRITAAASRLL
TVDSSDSSFYGLDRLNAQVRAMVPTHPALVLLWCQILLLVSHTDHRWWAEVQQTPRRRSL
SSTKSLSPQMSGEEGDSDAASKPGMCNREIVRRGALILFCDYVCQNLHDSEHLTWLIVNH
IQDLINLSHEPPVQDFISAVHRNSAASGLFIQAIQSRCENLSAPTTLKKTLQCLEGIHLS
QSGAVLTLYVDKLLCTPFRVLARMVDTLACRRVEMLLAANLQSSMAQLPVEELTRIQDYL
QSSGLAQRHQRLYSLLDRLRLATAPGSRGPSPPVTSHPLDGDGPLALETVIPDKDWYLRL
VKSQCWTRSDSALLEGAELVNRIPPSDMSTFMMNSEFNLSLLAPCLGLGMREVSGGQRSP
LFEAARLATLDRVTGLVQQLPAAHHVFQPFLPAEPTAYWNKLNDLFGDAVLYRSLTTLAR
ALAQYLLVFSKLPGHLHLPPEKERDTVKFVVMTLEALSWHLIHEQIPLSLDLQAGLDCCC
LALQLPSVWSALSSPEMVTHACSLIHCVRFILEAIVVQPGDQLLSPDRRMNTPKAAGEDE
VDSNTQNPAYITAACGMVAEMVEALPSVLALGHKRNSSTPAFLTSVLRNIIISLARLPLV
NSYTRVPPLVWKLGWSPKPGGDFGTSFPEIPVEFLQEKEVFKEFIYRINTLGWTSRTQFE
ETWATLLGVLVTQPLVMEQEESPPEEDTERTQINVLAVQAITSLVLSAMTVPVAGNPAVS
CLEQQPRNKPLKALDTRFGRKLSIIRGIVEQEIQAMVSKRENVATHHLYQAWDPVPSLSP
ATTGALIGHDKLLLQINPERELGNMSYKLGQVSIHSVWLGNSITPLREEEWEEEEEEEAD
VPTSASPPTSPVNSRKHRAGVDIHSCSQFLLELYSRWILPSGSARRTPIVLISEVVRSLL
VVSDLFTERTQFEMMYLTLTELRRAHPAEDEILIQYLVPATCKAAAVLGMDKAVAEPVSR
LLESTLRSSHLPSRVGALHGALYVLECDLLDETAKQLVPVISDYLLSNLKGAAPCVNVHS
QQHVLVMCATAFYLIENYPLDVGPEFSASVIQMCGVMLSGSEESTPSIIYHCVLRGLERL
LLSEQLCRLDAESLVKLSVDRVNVHSPHRAMAALGLMLTCMYTGKEKISPGRTSDPSPAA
PDSESVIVAMERVSVLFDRVRKGFPCEARVVARILPQFLDDFFPPQDVMNKVIGEFLSNQ
QPYPQFMATVVYKVFQTLHSSGQSSMVRDWVMLSLSNFTQRSPVAMAVWSLSCFFVSAST
SPWVSAVLPHVISRMGKLERVDVNLFCLVATDFYRHQIEEELDRRAFQSVFEVVAAPGNP
YHRLLTCLRNVHKVASC
NT seq
9414 nt
NT seq
+upstream
nt +downstream
nt
atggcgactctggaaaagctgatgaaggccttcgaatccctcaagtctttccagcagcag
cagcagcagcagcaacagcagcagcagcagcagccgcagccgccgccgccgccgcctcag
ccccctcagccgctgccgcaggcgcagccgccgctgcctcagcctcagccgccgcccccg
ccgccgcccccgccgccccccggcccggccgtggccgaggagccgcttcaccgaccaaag
aaagaactctcagccaccaagaaagaccgtgtgaatcactgtctgacgatatgtgagaac
atagtggcacagtcactcagaaattctccagaatttcagaaacttctgggcatcgctatg
gaactcttcctgctgtgcagtgatgatgcagagtcggatgtcaggatggtggctgacgag
tgcctcaacagagtcataaaagcgctgatggactcgaatcttccgcggttacagcttgaa
ctctataaggaaatcaaaaagaatggcgccccccggagcctgcgtgctgccctgtggagg
tttgcggagctggctcacctggttcggcctcagaaatgcaggccttacttggtaaacctt
ttgccctgcctgactcgaataagcaagagacccgaggaatctgttcaggagaccttggct
gcagcagtacctaaaattatggcttcttttggcaattttgcaaatgacaatgaaattaag
gttctattgaaggctttcatagcgaatctgaagtcaagctcgcctaccattcggcgtact
gcagctggctcagcagtgaccatctgccagcactccagaaggacgcagtacttctatagc
tggctactgaacgtgctcctgggcttgctggttcctgttgaggacgaacactctaccctc
ctgattctcggagtgctgctcacgttgaggtatttggtgcccttgctgcagcagcaggtc
aaggacacgagcctgaaaggcagctttggggtgacacggaaagaaatggaagtctgtccc
tcaactgagcagctcatccaggtttacgaactgaccttgcattacactcagcaccaagac
cacaacgccgtgactggggcgctggagctcctgcaacagctcttcaggacgcccccgccc
gagctcctgcaggccttgaccgcgccgggcggcgggcagcggagcggcgtgcagtatggg
cccggcggccggagccgcagcggcagcatcgcggagctcctagccggagggggttcttca
tgcagccctgtcctttcaagaaaacaaaaagggaaagtgctcttcggagacgcagcagcc
ttggaggatgactccgagtccaggtcggagggcagcagccccgccttcgcagcctcagtc
aagggtgagattggtggtgagctggcggcctcttctggagtctccactcctggctccgcc
ggttcaactgccgactccgtggggcacgacatcatcaccgagcagccccgctcacagcac
acgctgcagccggactcggtggatctgaccggctgtgacttggcgagcgctgccaccgac
ggggatgaggaggacatcctgagccacagctctagccagatcagtgctgtcccgtctgac
ccagccatagacctgaacgatggcacccaggcctcctccccagtcagtgacagttcccag
accaccaccgaagggcccgattcggctgtgactccttcagacagttctgaaatcgtgtta
gatggggccgacagccagtattcggggatgcagatcggacagccacaggacgaggatgag
gaggccgcgggcattcttccggaggaagacgtagatgctttccgaaactccgcagctgcc
cttcagcaagcacatttattgaaaagcatgggccacagccggcggccctccgacagcagt
gtggatacgtttgtctcaagagacgaagctgccgaagcaggagatcaagaaaacaagcct
tgccggatcaaaggtgacataggacagtctaccgatgacgattctgttcctcttgtccat
tgtgttcgccttctgtcggcttcgtttttgctgactggggagaagaatgtgttggttccg
gacagggacgtgagggtcagcgtgaaggcactggcactgagctgtgtgggagccgctgtg
gcccttcatcctgagtctttcttcagcaaactttacaaagtacctcttgactccgtggag
taccctgaggagccatatgtgtcagacatcctgaactacatcgatcatggagacccccag
gtcagaggagccacggccgttctctgtgggaccctcatctcctccaccctgagcaggtcc
cgcttccaagtgggagactggatgggcaccgttagagctctgacaggaaatacattttct
ctggaggattgcattcctttgctgcggaaaactttgaaggatgaatcttccgtcacttgc
aagttggcctgcacagctgtgaggcactgtgtcatgagtctgtgtagcagtagctccagt
gaactgggactgcagctgatcaccgatgtactgagcctgagggacagctcctactggctg
gtgaggacagagcttttggagacgctcgcagagattgactttaggttggtgagctttttg
gaggcaaaagcagaaaatctacacagaggggcccatcattacacggggcttttaaaactg
caggaccgagtgctccatgacgtcgtcatctacttgcttggggacgaagaccccagggtg
cgacacgttgccgcagctgcactgatgaggcttgtcccgaagctgttttataaatgtgac
caaggacaggccgacccagtggtggctgtggcgagagaccaaagcagcgtttacctgaaa
cttctcatgcacgagactcagcccccatctcacttctccgtcagcaccataaccagaata
tacagaggctataacctactgccgagcatgacagatgtcactgtggaaaataacctctcg
agagtcattgcggcagtttcccatgagctggtcacgtcgaccacgcgagcacttacgttt
ggatgctgcgaggctttgtgtcttctttccactgcctttccagtctgcgtttggagttta
ggctggcactgtggggcacccccgctgagcgtgtccggtgagtccaggaagagctgtact
gttggcatggccacggtcatcctcaccttgctctcgtcagcttggttcccgctggacctc
gcagcgcaccaggatgcgctggtgctggccggaaacctgctcgcagccagtgcccccaga
tctctgagaagttcgtggacctctgaggaagaggccaacccagcagccgccaagcaggaa
gaggtctggccggctctgggtgaccggaccctggtgcccatggtggagcagctcttctcc
cacctgctgaaggtgattaatatctgcgcacacgtgctggacgatgtggctcctggaccg
gcaataaaggcagccttgccgtccctaaccaaccctccttctctaagtccgatccgccgg
aagggaaaggagaaagagccgggagagcaggcctctgtgcccttgagccccaagaaaggc
agcgaagccagtccagcctctcgacaatccgatgcctcagggcctgttacagcaaataag
tcctcatcactggggagtttctaccaccttccttcatacctcaaattgcacgatgtcctg
aaagctactcacgctaactataaggttaccttggaccttcagaacagtgctgaaaagttt
gggggctttctgcgttctgccttggatgtgctctctcagatcctagaattggcaacgctg
caggacatcgggaagtgtgttgaggagatcctaggctacctgaaatcctgtttcagtcga
gaaccgatgatggcaactgtttgtgttcagcagttgctgaagactctctttgggacaaac
ttggcctcccagtttgatggcttgtcttccaaccccagcaagtcccagggccgagcgcag
cgtctgggctcctccagcgtgaggccgggcttgtaccactactgcttcatggctccctac
acgcacttcacccaggccttagccgacgccagcctgaggaacatggtgcaggcagagcag
gaccacgacgcctcagggtggtttgacgtgcttcagaaagtgtctacccagttgaagacg
aacctcaccagcaccactaagaaccgcgcagataagaacgctattcacaatcacattcgt
ttgttcgagcctctggttataaaagctttaaagcagtacacaaccacaacgtctgtgcag
ctacagaggcaggtcttagatttgctggcacagctggttcagttacgggtcaattactgt
cttctggattcagatcaggtgtttattggatttgtgctgaagcagttcgaatacattgaa
gtaggccagttcagggaatcagaggcaattattccaaacatctttttcttcctggtatta
ctgtcttacgagcgctatcattcaaaacagatcattggaatccctaaaatcattcagctc
tgtgacggcatcatggccagcgggaggaaggctgtgacacatgccataccggctctacag
ccgatagtccatgacctgttcgtactgagaggagccaataaagctgatgcaggaaaagag
ctcgaaacccagaaagaagtggtggtgtccatgctgctgagactcatccagtaccatcag
gtgctggagatgttcatcctggtcctgcagcagtgccacagggagagcgaggacaagtgg
aagcggctgtcccggcagatcgccgacgtcatcctcccgatgttggccaagcagcagatg
cacattgattctcacgaagcccttggcgtgttaaatactttatttgagattctggcccct
tcctccctccgtcccgtggacatgcttttacggagtatgttcgtcactccagacacaatg
gcacctgtgagcactgttcagctgtggatatcaggaatcctagccattttgagggttctc
atttcccagtcaactgaagacattgttctttctcgtattcaggagctctctttctctcca
tatttaatctcctgtccaataattaataggctaagagagggggacagtacttcgacacca
gaagaacacagtgaagggagacaaatgaagagcttgccggaagaaacattttcaagattt
ctactacaactagttggcattcttttggaggatattgttacaaagcagctcaaagtggaa
atgagtgaacagcaacatactttctactgccaagaactgggcactctgctgatgtgtctc
atccacatcttcaagtctggaatgttccgtaggatcacagcagccgcctccagactcctc
acggtggacagcagcgacagcagcttctatggcctggacaggctgaacgcgcaggtgcgc
gccatggtgcccacgcatccggcgctcgtgctgctctggtgccagatcctgctgcttgtc
agccacaccgaccaccgctggtgggcagaggtgcagcagacccccaggagacgtagtctg
tccagtacgaagtcactcagcccccagatgtccggagaggagggggactccgacgcggcc
agtaaacccggaatgtgcaacagagaaatagtgcggcggggagctctcattctcttctgc
gattatgtctgtcagaacctacacgattcagagcacttaacgtggctcatcgtgaatcat
attcaggacctgatcaatctgtcccatgagcctcccgtgcaggatttcattagtgctgtt
caccggaactccgccgccagcggcctcttcatccaggcaattcagtctcgttgtgagaac
ctttcagcccccaccaccctgaagaagacgcttcagtgcttggaagggatccacctcagc
cagtcgggcgccgtgttaacactgtatgtggacaagcttttgtgcaccccgttccgagtg
ctggctcgcatggtcgacacccttgcctgtcgccgcgtggaaatgcttttggccgcaaat
ttgcagagcagcatggcccagttgccggtggaggaactaaccagaatccaggactacctt
cagagcagcgggctggctcagagacaccagaggctgtactccctgctggacaggcttcgt
cttgctaccgcaccgggctcccgtggcccttctcctccggtcacgtcccacccgctggac
ggggatgggcccctggcactggagacagtcattccagacaaagactggtacctacgtcta
gtcaaatcccagtgctggactaggtcggattctgcgctgctggaaggggcagaactggtg
aatcggattcctcccagtgacatgagcacgttcatgatgaactcggaattcaacttaagc
ctgttggcgccgtgcctgggccttggcatgcgcgaagtctccggaggccagaggagtcca
cttttcgaagcagctcgcctggcgaccctggaccgtgtgaccggcctggtgcagcagctc
cctgccgcccaccacgttttccagccgttcctgcccgcagagcccaccgcctactggaac
aagttgaatgatctatttggggatgctgtgttgtatcgctccttgaccactctggcccgg
gctctggcccagtacctgctggtattctccaaactgcccggccacttgcaccttcctcct
gagaaggagagggacacggtgaagtttgtggtcatgaccctcgaggccctgtcgtggcat
ttgatccatgagcagatcccgctgagtctggaccttcaggcgggcctggactgctgttgc
ctggccctgcagctgcccagcgtctggagcgcactctcctccccagagatggtgacccac
gcctgttctctcatccactgtgtccgcttcatcctggaagccattgtggtgcagcctggg
gaccagcttcttagtccagaccgaaggatgaacaccccaaaggctgccggagaggacgaa
gtagattcaaacacacaaaacccggcctatattaccgcagcctgtgggatggtggcagaa
atggtggaggctttgccgtcggtgttggccttgggccataaaaggaatagcagcacccca
gcgtttctcacatcggtgctcaggaacatcatcatcagcctggctcgcttacccctcgtc
aacagctacacgcgcgtcccccccctggtttggaaacttggatggtcacccaaaccggga
ggggattttggtacatcgtttcctgagatcccagtggagttcctccaggagaaggaggtc
tttaaagagttcatctatcgcatcaacactctagggtggaccagccgcacccagtttgag
gaaacgtgggccaccctcctcggtgtcctggtgactcagcccctcgtgatggagcaggag
gagagcccgccggaagaagacacggagaggacccagatcaacgtcctggccgtgcaggcc
atcacctccctggtgctgagtgcgatgactgtgcccgtggccgggaacccggccgtgagc
tgcctggagcagcagccccggaacaagcccctgaaagctctcgacaccaggtttgggagg
aagctgagcattatcagaggaattgtggagcaagaaatccaagcaatggtttcgaagaga
gagaatgtcgccacccatcacttgtaccaagcgtgggaccccgtcccttctctctctcca
gctactacaggtgccctcatcggccacgacaagcttctgctgcagatcaaccctgagcgg
gagctggggaacatgagctacaagctcggccaggtgtccattcactccgtgtggctgggg
aacagcatcacgcccctgagagaggaagagtgggaggaggaggaggaggaggaggccgac
gtccccacgtccgcatcaccgcccacatcgccggtcaactccaggaagcaccgggctgga
gtcgacatccactcctgttcccagttcttgcttgaactgtatagtcgctggatcctgccg
tcagggtcagccagaaggacccccatcgtgctgatcagcgaagtggtccgatctctccta
gtggtctcagacttgttcactgagcgcacccagtttgagatgatgtatctgacgctgacc
gagctgaggagggcgcaccctgcagaagacgagattctcattcagtacctggtgcctgcc
acctgcaaggcggctgccgtcctcggaatggacaaggccgtggccgagcccgtcagccgg
ctgctggagagcacactgaggagcagccacctgcccagcagggtcggggccctgcacggc
gccctctacgtgctggagtgtgacctcctggatgagacggcgaagcagcttgtccctgtc
atcagcgactacctcctgtccaacctcaaaggggcagccccctgcgtgaatgttcatagc
caacagcacgtgctggtgatgtgtgccaccgccttctacctgattgagaactatcccctg
gacgtaggcccggaattctctgcgtcagtaattcagatgtgtggggtgatgctgtccggg
agtgaggagtccactccgtccatcatctaccactgcgtcctgcggggcctggagcgtctt
ctgctctccgaacagctgtgccggctggatgctgagtccctggtcaagctgagtgtggac
agagtgaacgtgcacagcccgcaccgggccatggctgccctgggcctgatgctcacctgc
atgtacacagggaaggagaaaatcagcccaggcagaacctcagaccccagccccgccgcc
ccagacagcgagtccgtgatcgtggctatggagcgtgtgtccgttcttttcgacagggtc
aggaaaggattcccctgtgaagccagagtggtggcacggatccttcctcagtttttagat
gacttcttcccaccccaggatgtcatgaacaaagtcattggggaatttctgtccaaccag
cagccatacccacagttcatggccaccgttgtgtacaaggttttccagaccctgcacagc
agtgggcagtcgtccatggtccgggactgggtcatgctgtccctctcgaacttcacccag
aggagcccggtggccatggctgtgtggagcctctcctgcttcttcgtcagtgcttccact
agcccctgggtctctgccgtccttccccacgtcatcagcaggatgggcaagctggagcga
gtggacgttaacctcttctgcctggtggccacagacttttacagacaccagatagaggag
gagctggaccgccgggccttccagtccgtgttcgaggtggtcgcggctccgggaaaccca
taccatcgactgttgacttgtttgcggaacgtccacaaagtcgcctcgtgctga
DBGET
integrated database retrieval system
