Lynx rufus (bobcat): 124525643
Help
Entry
124525643 CDS
T08475
Name
(RefSeq) probable helicase senataxin isoform X1
KO
K10706
ATP-dependent RNA/DNA helicase, senataxin [EC:
5.6.2.5
5.6.2.3
]
Organism
lruf
Lynx rufus (bobcat)
Pathway
lruf05014
Amyotrophic lateral sclerosis
Brite
KEGG Orthology (KO) [BR:
lruf00001
]
09160 Human Diseases
09164 Neurodegenerative disease
05014 Amyotrophic lateral sclerosis
124525643
09180 Brite Hierarchies
09182 Protein families: genetic information processing
03021 Transcription machinery [BR:
lruf03021
]
124525643
Enzymes [BR:
lruf01000
]
5. Isomerases
5.6 Isomerases altering macromolecular conformation
5.6.2 Enzymes altering nucleic acid conformation
5.6.2.3 DNA 5'-3' helicase
124525643
5.6.2.5 RNA 5'-3' helicase
124525643
Transcription machinery [BR:
lruf03021
]
Eukaryotic type
RNA polymerase II system
Other transcription-related factors
Transcription termination factor
124525643
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
AAA_11
AAA_12
AAA_19
UvrD-helicase
AAA_30
AAA_22
ResIII
nSTAND3
SLFN-g3_helicase
Helicase_RecD
AAA_16
UvrD_C_2
Motif
Other DBs
NCBI-GeneID:
124525643
NCBI-ProteinID:
XP_046954128
LinkDB
All DBs
Position
Unknown
AA seq
2669 aa
AA seq
DB search
MSTCCWCTPGGISTADFLKRYASRTHAGEFQTADEDLCYCLECVAEYHKARDDLPFLHEV
LWELETLRLINHFEKSMKAEIGDDDELYIVDNNGEAQLFDFTGQDFENKLRVPLLEILKY
PYLLLHERVNELCVEALCRMEQANCSFQVFDKHPGIYLFLVHPNEMVRRWAILTARNLGK
VDRDDYYDLQEVLTCLFKVIELGLLEDPDIYTSSVLEKGKLILLPSHMYDTTNYKNYWLG
ICMLLTILEEQAMDSLLLGSDKQNDFMQSILHTMERQADDDSVDPFWPALHCFMVILDRL
GSKVWGQRIDPIEAFQTIINNMSYNREIQNIRNSSVRTKSEPESYLGDTVTCSQMVYNYN
PEKTKKDSGWRSAICPDYCPNMYEEMETLASVLQSDIGQDMRVHNSTFLWFIPFVQSLMD
LKDLGVAYIVEVIHHLHSEVKDVLNQTDAVCDKVTEFFLLILVSVIELHRNKKCLHLLWV
SSQQWVEAVVKCAKLPTAAFARSSEKSSGNCSKGAAVISSLSLHSMPSNSVQLACVQLIR
SLLKEGYQLGQQTLCKRFWDKLNLFLRGNLSLGWQLTTQETHELQTCLKQIIRNIKFKVP
QCSTFVDLAPVCKTPPASYNKEESEQTGKKSKKGLHCLENSSPTFSKGPMKAEAFQMPEN
RLVKAGNASEEDSEHNYIKDLKLEGRLSAESCIKQGSKRLVPERAQDAVKTSKGKQKSVK
ENPTDSRNGPERGCDRGVIIAARSWTDSGTDSLEKASTSTEDFSFKDDVLGKTSKGKTKG
QKAEICAKLSHVIKKQHRKSTLIDDGNLEEKLTVSTIDSFFSRKDSGGQKGDGFINHLSL
DPDDVPDDKNGERKSQNSLLLKKKQFKSKELDIFSSHENSCQIQECQADGKDLVSFTEMT
DTCVKKTSPFKDPVTLLESRDKEVGKSTTSQVSSHLREQVPSLSPQSNTLTDSQIDRDLH
NLSLIAQASVIKFPSESTQKSSSQLQRKVRDKRCFTANPNNAGEACRGQVIIISDSDDDD
GDEGILGFEKHVQRDKIGIKKEYPEEHSSAASTNAEQKLTEEEGAKSLLEFEESDSQFFE
FESPHEVFSVWQDQEPDNKNSVQEDENNSRLTHINDVTNDWGYDTDYVSEEVIKKVAEGI
EKHTEPQSGSSVGEFCETEVKKRKRKRYEKPVAEDPLRPSPSERNEDQSDNERGLTENDP
KSIELRSSSRSNLQRATTDSLKKSSPKLRTYSKPVRRVPHSKTKKTHSDTKKGQNKSSNY
ISCRTTPAIVPPKILRQCPEPTSAVEKLGLKKAPRRAFDLSQRSLGYLVQLRDHGKTVGV
VDTRKKTKLISPQTLSVRNNKKLLTSQDLQSRRQAKHKSKQKRQGSLGSESRAPTRAGLR
SAKNPDTLVPESDSSDCRAKGGAEVGANNTGKPSIKRASSEPEPVKTKRVSQAADDPCLS
NQCASVVLNGRKATHEAIVSTSADPLGGGDLTEHRLELTALKEGEPRSNSDSEDENIFLT
QHDPADMDLCSQMENGNEKLIEIVHGKDTALMEEESWSSTKCKYKDCVEAAQNQGEYCSK
HCEAKAVDEGVFRKPGLPPSASKRPSTAKVFSSSSTSRIANLSKSLESTSAPPPALKQKS
NGVPSGLRVAQPASVLSPKPVGEVKSLSDVLRPQTLNNSNKPGYKLTFGESRSLSASSAV
NVLLSSQSISDTFVKEVLKWKYEMFVNFDQCGPPTSLCQSISRPVPVRFQDCGDYFNVFF
PLMILNTFETVAQEWISSPNKEKFYQLHVRKFPADYKKYWEFVVHLEECELTKQLHPKEN
DLVFLVLEKQNGEKKNTERNRMPDLHEYHCGYVHKFRRTSVMRNGKSECSLSIQTQDNLP
LSLNELVKCTVISSLVTTQRKLKAMSLLSGRNQLARAVLNPNPMDFCTKDLLTTTSERII
AYLKDFNEDQKKAIETAYAMVKHSPSVAKICLIHGPPGTGKSKTIVGLLYRLLTENQRKG
RSDENSNAKIKQNRVLVCAPSNAAVDELMKKIILEFKEKCKDKKNPLGNCGDINLVRLGP
EKSINNEVLRFSLDSQVNHRMKKDLPSHVQEMHRRKEFLDHQLDELSRQRALCRGGKETQ
RQELDEKIAKVSKERQELASKIKEVQGRPQKTQSIIILESHVICCTLSTSGGLLLESAFR
GQGGVPFSCVIVDEAGQSCEVETLTPLIHRCNKLILVGDPKQLPPTVISMKAQEYGYDQS
MMARFCKLLEDSVEHNVIGRLPVLQLTVQYRMHPDICLFPSNYVYNRSLKTNRLTETNRC
SSDWPFQPYLVFDVGDGSERRDNDSYINVQEIKLVMEIIKLIKDKRRDVTFRNIGIITHY
KAQKTMIQKDLDKEFDRKGPAEVDTVDAFQGRQKDCVIVTCVRANAMQGSIGFLASLQRL
NVTITRAKYSLFILGHLRTLMENQHWNHLIQDAQKRGAIVKTCDKNYRHDAAKILKLKPV
LQRSLTHPPTVAPEVARPQGGLPSSKPDGEFAKTSFPSSLYHVPSGCKESTGAVTTKDPE
RPPIQDRLRDPRLLRRLGIDPEAKGTCPRDPQPLSPQHPGATPPSGEPGFPLSHQDLGGA
QLSTARGATLSNQNPPVQWEPPAAGTDVSASKRACDWEGGLSRRRETRAFSEGDRETQSP
ESRHPKRRSGWDNRRLEEEDRGSKRRKFL
NT seq
8010 nt
NT seq
+upstream
nt +downstream
nt
atgagcacatgttgttggtgtacgcccggtggtatttccaccgctgacttcctcaagcgc
tatgcgtccaggactcatgccggggaatttcagacagccgacgaagacctctgctactgc
ctggagtgtgtggccgagtaccacaaagcacgcgacgacctgcccttcctgcatgaggtt
ttgtgggaattagaaaccttacgtctcataaatcattttgaaaaatccatgaaggcagaa
attggagacgatgatgaattgtacatagtagacaacaatggagaggcacagctgtttgac
ttcactggccaagactttgaaaataagcttcgagttcctcttcttgaaatcctgaagtat
ccgtatctgcttttacacgagcgtgttaacgaattgtgtgttgaagcactttgtcggatg
gaacaagctaattgctcctttcaggtttttgacaaacatccaggcatttatttgtttctg
gtccatcccaatgaaatggttcggcgttgggctatcctgaccgcaaggaacttgggaaaa
gtggacagagatgattattatgatctgcaggaggttttgacttgtctttttaaagtcatt
gagttggggcttctggaagatccagacatctacacttcttctgtcctcgagaagggtaaa
ctgattcttctgccttcgcacatgtacgataccaccaactacaagaactattggctaggt
atttgcatgttgctgaccattcttgaggagcaggctatggactccctgttgctgggctca
gacaaacagaatgatttcatgcaatcaatacttcacaccatggagaggcaagcagatgat
gatagcgtggatcctttctggccagcattacactgtttcatggtgattctggatcgcctc
ggatcaaaggtctggggtcaacgcatcgatcctattgaggcgtttcagaccattatcaat
aacatgagctacaatagagagatccaaaatatacggaacagctctgtaaggaccaaatcg
gaaccggagtcgtatttgggtgatacagtgacttgtagccagatggtgtacaattacaac
cctgaaaagaccaaaaaggattccgggtggagatcagccatttgcccagattactgtcct
aacatgtacgaagagatggaaacgttagccagtgtgcttcagtcagatattggtcaagac
atgcgtgttcacaatagcacgtttctgtggttcatcccctttgttcagtccctcatggat
cttaaggatttgggtgtggcttacatagtagaggtgattcaccatctgcactctgaagtc
aaagatgtcctcaaccaaacagatgccgtgtgtgacaaagttactgagtttttccttctg
attttggtgtccgtgattgaactgcacagaaataaaaaatgtttgcacttgctgtgggtt
agttcccagcagtgggtggaggctgttgtaaaatgcgccaagcttcccaccgccgcgttt
gcacggagttctgagaagtcatctggaaattgctccaaaggagcagcagtgatatcgtct
ctgtcactgcattcgatgccgtctaattctgtccagctggcttgtgtgcagctgatcaga
agtctccttaaagaagggtatcagcttgggcagcagactctgtgcaagcgattctgggac
aagctcaacttatttctgcgtgggaatttatctctaggttggcagttgactactcaggaa
acccatgagttacaaacttgtttaaagcaaattattagaaacataaaattcaaagtacct
cagtgtagcacttttgtggatctggctcccgtatgtaaaacccctcctgcgtcttacaat
aaagaagaaagtgaacagacagggaagaaatctaaaaaaggcctgcactgtctggaaaac
tccagcccaacattttctaaaggaccaatgaaagctgaggcgtttcagatgccagagaat
agattggtcaaagcaggtaacgctagcgaagaggatagtgagcacaattacataaaagat
ttgaaactagaaggccgtctctcagcagagtcatgcataaagcagggtagcaaaaggctt
gtcccggaaagagctcaagatgcagttaaaacaagtaaagggaagcagaagtctgtgaag
gagaatcctacggattccagaaatggtccggaaaggggatgtgacagaggggtgataata
gccgcacgttcgtggactgattctggcaccgactctctggagaaggcgtccacatcaact
gaggatttctctttcaaggatgatgttcttggcaaaacctcgaaaggaaaaactaaggga
cagaaagctgaaatctgtgctaagttatctcatgtaataaagaagcaacacaggaaaagt
actttgatcgatgatggcaatttagaggaaaaactgacggtgtctaccattgacagtttc
ttctcaaggaaagattcaggaggtcagaaaggggatggcttcataaaccatctctcttta
gaccctgatgacgttcccgatgataaaaacggggagcgaaaatctcaaaacagtttattg
ctgaagaagaaacaattcaagagcaaagagttagatattttctcttcccatgaaaatagc
tgtcaaatacaggaatgccaagcagatggtaaagatttggtctcgtttacggaaatgacc
gatacttgtgtgaagaaaacgtctcccttcaaagaccccgtgactcttcttgagtcgaga
gataaggaagttggcaagagtaccaccagtcaggtgtcttctcacttgagggaacaggtt
cctagcctcagtccacagtccaacaccttgacagattcccagatagaccgagacctccac
aacttatctttgatagcccaagccagtgttattaagtttccatcagagtcaactcaaaaa
agctcgtcccagctacaaagaaaagtcagagataaaaggtgtttcacagctaacccgaat
aatgctggagaagcctgccggggccaggtgattattatttcagattctgatgatgatgat
ggtgatgaagggattctgggttttgagaaacacgttcaacgagataaaataggcatcaag
aaagaatatccagaggagcatagttcagcagctagtacaaacgcggaacagaagctgacg
gaggaagaaggggcaaagtccctattggagtttgaggagtcggattcgcagttttttgag
tttgaaagtccgcacgaggtgttttcagtttggcaagatcaggaaccagacaacaagaat
tcagttcaagaggatgaaaacaattcacgtctgacccacataaacgatgtcacgaatgac
tggggttatgatacagattatgtatctgaagaggttattaagaaagtagcagagggcatt
gaaaaacacacagaaccacagagtggtagttctgtcggggaattttgtgaaactgaagtg
aaaaaacgtaagagaaaacgatacgaaaaacctgtagctgaagatcctctgaggccttca
ccttctgagagaaatgaggaccagtctgataatgagagaggtctgactgaaaatgatcct
aaaagtatagagctgaggtcaagttccaggtcgaatcttcaaagagccactacagattca
ctaaagaagtcttctccaaagcttcgtacttactccaaacccgttaggagagtcccgcat
tctaaaactaagaaaacacattcagataccaaaaaagggcagaataaaagttcgaattac
ataagttgtaggacgactcctgctatagtcccaccgaagatacttcgccagtgccctgaa
ccaacttcagctgttgaaaaacttggtctgaaaaaggctcctcgtagggcattcgattta
tctcagcgatctctagggtatttagttcagttacgggaccatggcaaaaccgtgggagtg
gttgataccagaaaaaagactaagctaatttctcctcagactctctctgtcagaaataat
aagaaactgttgacaagtcaagatcttcagtcgcgaaggcaggcgaaacacaaatcaaag
cagaagaggcaaggctctctgggttctgaaagcagagctcctacaagagcagggctgcgt
tcagcaaagaatcctgacactcttgtcccagaatccgatagctcagattgtcgtgctaaa
ggaggcgccgaggtgggtgctaacaatactgggaagccatcaataaaacgcgcgtcttct
gaaccagaacccgtgaaaacgaaacgtgtttctcaggcggctgatgatccttgcctctcg
aaccagtgcgcttctgtcgtgttaaatggaagaaaagcaacacatgaagccatcgtctct
acgtcagctgaccctttaggtggaggcgacctaacagaacatcgtttagagttgaccgct
ctgaaagagggagagcccagatccaacagtgactcggaagatgagaatatatttctaacc
cagcacgatcccgcagatatggatttatgttcacaaatggaaaatggtaacgagaaactc
attgaaatagttcatggaaaagatacagctctgatggaggaagaatcttggagcagcaca
aaatgtaagtacaaggattgtgtcgaagccgcgcaaaaccagggtgaatactgctccaaa
cactgcgaagctaaagcagtggatgaaggtgtgtttcgtaaaccgggcttgcccccctct
gcgtccaagagaccctccactgccaaggtctttagctcaagtagtacttcacgaattgct
aatctttcgaagtctttggagagtacctccgcaccgccaccggccctcaaacagaagtca
aacggggtgccatctggtttgagagtcgcacagccagcctctgtgttgtctccaaagcca
gtgggtgaggtgaagagtttgtctgatgttctccgtcctcagactctgaataattccaac
aagccaggttacaagcttacctttggcgaaagcagatctctttcggcttcctctgcggta
aacgttctcttgtcctcacagtctatctcggacacctttgttaaagaggtcttaaagtgg
aagtacgaaatgtttgtgaactttgatcagtgtgggccccctaccagcctttgtcagtcc
atctcaagaccggtgcctgtcagatttcaagattgtggagattatttcaatgtttttttc
cctttgatgatactgaatacttttgaaacggtggcacaggagtggatcagctctccaaac
aaagagaagttctatcagttgcatgtacggaaatttcctgctgattataaaaagtactgg
gagtttgtggttcatcttgaggaatgtgaactaactaaacagctgcatccaaaggaaaat
gatttggtgtttttggttcttgaaaaacaaaatggagagaagaagaacacagagagaaat
cgcatgccggatctccacgaatatcactgcggttatgttcataaatttcgccgcacttca
gtcatgcgtaatgggaaatctgagtgttccctttccatccagactcaagataatttgcca
ctcagtttaaatgaactcgtgaaatgcactgtaatcagttctctggtaactacacaaagg
aagttgaaagccatgtctttgttgagtggacggaaccaactagccagagctgttctgaac
ccaaaccccatggacttctgtacgaaagatttactgactacgacgtctgagagaatcatc
gcctacttgaaagatttcaacgaagaccaaaagaaagcgatagaaactgcctacgccatg
gtcaaacactccccgtcagttgccaagatctgtttgattcatggaccacctggaacagga
aaatcaaaaactatcgttggcctcctgtaccgcctgctgacagagaaccagaggaagggg
cgttcagatgaaaactccaatgccaaaatcaaacaaaaccgtgtccttgtgtgtgcgcct
tccaacgcggctgttgatgaacttatgaaaaaaatcatcctcgaatttaaagagaagtgt
aaagacaagaagaatcctttgggaaactgtggagatataaatttagtacgtctgggtcca
gaaaagtctattaataatgaggtcctaagatttagtttggacagccaagttaaccacaga
atgaaaaaagacttaccttctcatgttcaggagatgcatagaagaaaggaatttctggat
catcagctagatgaactttcccgccagcgtgctttatgccgaggtggaaaggaaacacag
aggcaagaattagatgaaaaaattgcaaaagtttcaaaagagaggcaggaactagcttct
aaaattaaagaggttcaaggacgcccacaaaaaacacagagcatcatcatcttagagtcc
cacgtcatctgctgcacactgagcacgagtggcggtttactgctcgagtctgcttttcgt
gggcaagggggtgtccccttcagttgtgtcatcgtcgatgaggctgggcagtcttgtgaa
gtggagactcttaccccgctcatccatcgatgtaacaagctgatcctcgtcggagaccca
aaacagctccctcccacggtcatctccatgaaagcacaggagtatggctatgaccagtca
atgatggctcgcttctgcaagctgctggaagacagcgtagagcacaatgtgatcggcagg
ctgcctgttttacagcttactgttcagtacaggatgcacccagacatatgtctcttcccc
tctaattacgtttataacagaagcttgaaaacaaatagactgactgaaaccaatcggtgt
tcatcagactggccatttcaaccttacctcgtgtttgatgtcggagacggttcagaaaga
cgggataatgactcatatataaatgttcaagaaataaaactggtaatggaaataattaaa
cttattaaagacaaaagaagggatgttactttccggaacattggcataataacccattac
aaggctcagaagacgatgattcagaaggatttggacaaagagtttgatagaaaagggccg
gcagaagtagataccgtggacgcgttccagggccgccagaaagattgtgttatcgtcacg
tgtgtcagagcaaacgccatgcaaggctccattggatttctggcaagtttgcaaagattg
aatgtcaccattacacgagccaagtacagcctcttcatcctcggacatttaaggaccttg
atggaaaatcagcactggaatcacctgattcaggacgcacagaagcggggtgccattgtc
aagacgtgcgacaaaaactacaggcacgacgcagccaagattctgaaactcaagcccgtc
ctgcagagaagtctgactcacccgcccaccgtggccccggaggtggccagaccccagggt
ggcttgcccagcagcaagccagacggtgaatttgccaagacgtctttcccttcctccctg
tatcacgtgccttctggctgtaaggaatccactggtgctgttaccaccaaggaccctgaa
agacctcctattcaggaccggcttcgggacccacgactgcttaggaggctgggcatagac
cccgaagccaaagggacgtgcccgagggatccgcagcccctgagcccccagcatcctggg
gccacgcctccctcgggggagcccggcttccctctgagtcaccaggacctgggtggtgcc
cagctgtccaccgccagaggggccacgctgagcaaccagaaccctcccgtgcagtgggag
cctccagctgccggtacggatgtctccgcgagtaaaagagcgtgtgactgggaaggaggg
ctcagccgcaggagagagaccagggctttcagcgaaggggaccgggagacgcagagccct
gagagccgtcacccgaagaggcgctccggctgggacaacaggagactggaggaggaagac
cgtggttccaagagaagaaagtttttatag
DBGET
integrated database retrieval system
