Lynx rufus (bobcat): 124526598
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Entry
124526598 CDS
T08475
Name
(RefSeq) TGF-beta receptor type-2 isoform X1
KO
K04388
TGF-beta receptor type-2 [EC:
2.7.11.30
]
Organism
lruf
Lynx rufus (bobcat)
Pathway
lruf04010
MAPK signaling pathway
lruf04060
Cytokine-cytokine receptor interaction
lruf04068
FoxO signaling pathway
lruf04144
Endocytosis
lruf04218
Cellular senescence
lruf04350
TGF-beta signaling pathway
lruf04380
Osteoclast differentiation
lruf04390
Hippo signaling pathway
lruf04520
Adherens junction
lruf04659
Th17 cell differentiation
lruf04926
Relaxin signaling pathway
lruf04933
AGE-RAGE signaling pathway in diabetic complications
lruf05142
Chagas disease
lruf05161
Hepatitis B
lruf05166
Human T-cell leukemia virus 1 infection
lruf05200
Pathways in cancer
lruf05202
Transcriptional misregulation in cancer
lruf05210
Colorectal cancer
lruf05212
Pancreatic cancer
lruf05220
Chronic myeloid leukemia
lruf05225
Hepatocellular carcinoma
lruf05226
Gastric cancer
lruf05415
Diabetic cardiomyopathy
Brite
KEGG Orthology (KO) [BR:
lruf00001
]
09130 Environmental Information Processing
09132 Signal transduction
04010 MAPK signaling pathway
124526598
04350 TGF-beta signaling pathway
124526598
04390 Hippo signaling pathway
124526598
04068 FoxO signaling pathway
124526598
09133 Signaling molecules and interaction
04060 Cytokine-cytokine receptor interaction
124526598
09140 Cellular Processes
09141 Transport and catabolism
04144 Endocytosis
124526598
09143 Cell growth and death
04218 Cellular senescence
124526598
09144 Cellular community - eukaryotes
04520 Adherens junction
124526598
09150 Organismal Systems
09151 Immune system
04659 Th17 cell differentiation
124526598
09152 Endocrine system
04926 Relaxin signaling pathway
124526598
09158 Development and regeneration
04380 Osteoclast differentiation
124526598
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
124526598
05202 Transcriptional misregulation in cancer
124526598
09162 Cancer: specific types
05210 Colorectal cancer
124526598
05212 Pancreatic cancer
124526598
05225 Hepatocellular carcinoma
124526598
05226 Gastric cancer
124526598
05220 Chronic myeloid leukemia
124526598
09172 Infectious disease: viral
05166 Human T-cell leukemia virus 1 infection
124526598
05161 Hepatitis B
124526598
09174 Infectious disease: parasitic
05142 Chagas disease
124526598
09166 Cardiovascular disease
05415 Diabetic cardiomyopathy
124526598
09167 Endocrine and metabolic disease
04933 AGE-RAGE signaling pathway in diabetic complications
124526598
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
lruf01001
]
124526598
Enzymes [BR:
lruf01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.11 Protein-serine/threonine kinases
2.7.11.30 receptor protein serine/threonine kinase
124526598
Protein kinases [BR:
lruf01001
]
Receptor serine/threonine kinases (RSTK): TKL group
TGFBR2 family [OT]
124526598
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
ecTbetaR2
PK_Tyr_Ser-Thr
Pkinase
ABC1
Haspin_kinase
Pkinase_fungal
Motif
Other DBs
NCBI-GeneID:
124526598
NCBI-ProteinID:
XP_046955613
LinkDB
All DBs
Position
Unknown
AA seq
569 aa
AA seq
DB search
MKSIHPLMHCGVFMSSRSKTGPLFGRTGGNSRMFNNGMMVTDNNGIIKFPQLCKFCDVRS
STCDSQKSCLSNCSITSICERPHEVCLAVWRKNDENITLETLCHDPKVTYHGIALEDSAS
PKCIMKEKKVLGETFFMCSCSTDECNDYIIFSEEYATNNPDLLLVIFQVTGVSLLPPLGI
AIAVIIIFYCYRVHRQQKLSPSWDTSKPRKLMEFSEHLAIILEDDRSDISSTCANNINHN
TELLPIELDTLVGKGRFAEVYKAKLKQNTSEQFETVAVKIFPYEEYASWKTEKDIFSDIN
LKHENILQFLTAEERKTELGKQYWLITAFHAKGNLQEYLTRHVISWEDLRTLGSSLARGI
AHLHSDHTLCGRPKMPIVHRDLKSSNILVKNDLTCCLCDFGLSLRLDPTLSVDDLANSGQ
VGTARYMAPEVLESRMNLENVESFKQTDVYSMALVLWEMTSRCNAVGEVKEYEPPFGSKV
REHPCVESMKDNVLRDRGRPEIPSSWLNHQGIQMVCETLTECWDHDPEARLTAQCVAERF
SELQHLDRLSGRSCSEEKIPEDGSLNTTK
NT seq
1710 nt
NT seq
+upstream
nt +downstream
nt
atgaaatctatacatccattgatgcattgtggagtatttatgtcatcaaggagcaaaacc
ggccctttatttggaaggactggggggaattcaaggatgtttaacaatggcatgatggtc
accgacaacaatggtatcatcaagtttccgcaactgtgcaaattttgtgacgtgagatct
tccacctgtgacagccagaaatcctgcctgagcaactgcagcatcacgtctatctgcgag
aggccgcacgaagtctgtctggccgtctggagaaagaacgatgagaacataaccctagag
acgctttgccatgaccccaaggttacctaccatggaattgctcttgaagactctgcttct
cccaagtgtattatgaaggaaaaaaaggtgttgggcgagactttctttatgtgttcctgt
agcaccgatgaatgcaatgactacatcatcttctcagaagaatacgccaccaacaaccct
gacctgttgttggtcatattccaagtgacaggcgtcagcctcctgccccccctggggatc
gccatagccgtcatcatcatcttctactgctaccgtgttcaccggcagcagaagctgagc
ccatcctgggataccagcaagccacgaaagctcatggagttcagcgagcaccttgccatc
attctggaagacgaccgctctgacatcagctctacctgcgccaacaacatcaaccacaac
acagagctgctgcccattgagctggacaccctggtggggaaaggccgcttcgccgaggtc
tacaaggccaagctgaagcagaacacttctgaacagttcgagaccgtggcggtcaagatc
ttcccttacgaggagtacgcctcctggaagacggagaaggacattttctcagacatcaac
ctgaagcacgagaacatactgcagttcctgacagccgaggagcgcaagacggagctgggg
aagcagtactggctgatcacggccttccatgccaagggcaacctgcaggagtacctgacg
cggcacgtcatcagctgggaggacctgcgcacgctgggcagctccctcgcccggggcatt
gcccacctgcacagcgaccacaccctgtgcgggaggcccaagatgcccatcgtgcacagg
gacctcaagagctccaatatcctcgtcaagaacgatctgacctgctgcctgtgtgacttt
gggctttccctgcgtctggacccgaccctgtctgtggatgacctggccaacagcgggcag
gtgggaactgcaagatacatggctccagaagtcctagagtccaggatgaatttggagaat
gttgagtcctttaagcagacggatgtctactccatggctctggtcctctgggaaatgaca
tctcgctgtaatgcggtgggagaggtgaaagagtacgagcctccatttggttccaaggtg
cgggagcatccctgtgttgagagcatgaaggacaatgtgctgagagaccgaggacgacca
gaaattcccagctcctggctcaaccaccagggcatccagatggtgtgcgagactctgacc
gagtgctgggaccatgacccggaggcccggctcacggcccagtgcgtggcagagcgcttc
agtgaactgcagcacctggacaggctctcggggaggagctgctccgaggagaagattccc
gaagatggctcgttgaacactaccaaatag
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