Lynx rufus (bobcat): 124527565 Help Entry 124527565         CDS       T08475                                  Name (RefSeq) GTPase HRas isoform X1   KO K02833   GTPase HRas Organism lruf  Lynx rufus (bobcat) Pathway lruf01521   EGFR tyrosine kinase inhibitor resistance lruf01522   Endocrine resistance lruf04010   MAPK signaling pathway lruf04012   ErbB signaling pathway lruf04014   Ras signaling pathway lruf04015   Rap1 signaling pathway lruf04062   Chemokine signaling pathway lruf04068   FoxO signaling pathway lruf04071   Sphingolipid signaling pathway lruf04072   Phospholipase D signaling pathway lruf04137   Mitophagy - animal lruf04140   Autophagy - animal lruf04144   Endocytosis lruf04150   mTOR signaling pathway lruf04151   PI3K-Akt signaling pathway lruf04210   Apoptosis lruf04211   Longevity regulating pathway lruf04213   Longevity regulating pathway - multiple species lruf04218   Cellular senescence lruf04360   Axon guidance lruf04370   VEGF signaling pathway lruf04371   Apelin signaling pathway lruf04510   Focal adhesion lruf04540   Gap junction lruf04550   Signaling pathways regulating pluripotency of stem cells lruf04625   C-type lectin receptor signaling pathway lruf04630   JAK-STAT signaling pathway lruf04650   Natural killer cell mediated cytotoxicity lruf04660   T cell receptor signaling pathway lruf04662   B cell receptor signaling pathway lruf04664   Fc epsilon RI signaling pathway lruf04714   Thermogenesis lruf04720   Long-term potentiation lruf04722   Neurotrophin signaling pathway lruf04725   Cholinergic synapse lruf04726   Serotonergic synapse lruf04730   Long-term depression lruf04810   Regulation of actin cytoskeleton lruf04910   Insulin signaling pathway lruf04912   GnRH signaling pathway lruf04915   Estrogen signaling pathway lruf04916   Melanogenesis lruf04917   Prolactin signaling pathway lruf04919   Thyroid hormone signaling pathway lruf04921   Oxytocin signaling pathway lruf04926   Relaxin signaling pathway lruf04929   GnRH secretion lruf04933   AGE-RAGE signaling pathway in diabetic complications lruf04935   Growth hormone synthesis, secretion and action lruf05010   Alzheimer disease lruf05022   Pathways of neurodegeneration - multiple diseases lruf05034   Alcoholism lruf05132   Salmonella infection lruf05160   Hepatitis C lruf05161   Hepatitis B lruf05163   Human cytomegalovirus infection lruf05165   Human papillomavirus infection lruf05166   Human T-cell leukemia virus 1 infection lruf05167   Kaposi sarcoma-associated herpesvirus infection lruf05170   Human immunodeficiency virus 1 infection lruf05200   Pathways in cancer lruf05203   Viral carcinogenesis lruf05205   Proteoglycans in cancer lruf05206   MicroRNAs in cancer lruf05207   Chemical carcinogenesis - receptor activation lruf05208   Chemical carcinogenesis - reactive oxygen species lruf05210   Colorectal cancer lruf05211   Renal cell carcinoma lruf05213   Endometrial cancer lruf05214   Glioma lruf05215   Prostate cancer lruf05216   Thyroid cancer lruf05218   Melanoma lruf05219   Bladder cancer lruf05220   Chronic myeloid leukemia lruf05221   Acute myeloid leukemia lruf05223   Non-small cell lung cancer lruf05224   Breast cancer lruf05225   Hepatocellular carcinoma lruf05226   Gastric cancer lruf05230   Central carbon metabolism in cancer lruf05231   Choline metabolism in cancer lruf05235   PD-L1 expression and PD-1 checkpoint pathway in cancer lruf05417   Lipid and atherosclerosis Brite KEGG Orthology (KO) [BR:lruf00001]  09130 Environmental Information Processing   09132 Signal transduction    04010 MAPK signaling pathway     124527565    04012 ErbB signaling pathway     124527565    04014 Ras signaling pathway     124527565    04015 Rap1 signaling pathway     124527565    04370 VEGF signaling pathway     124527565    04371 Apelin signaling pathway     124527565    04630 JAK-STAT signaling pathway     124527565    04068 FoxO signaling pathway     124527565    04072 Phospholipase D signaling pathway     124527565    04071 Sphingolipid signaling pathway     124527565    04151 PI3K-Akt signaling pathway     124527565    04150 mTOR signaling pathway     124527565  09140 Cellular Processes   09141 Transport and catabolism    04144 Endocytosis     124527565    04140 Autophagy - animal     124527565    04137 Mitophagy - animal     124527565   09143 Cell growth and death    04210 Apoptosis     124527565    04218 Cellular senescence     124527565   09144 Cellular community - eukaryotes    04510 Focal adhesion     124527565    04540 Gap junction     124527565    04550 Signaling pathways regulating pluripotency of stem cells     124527565   09142 Cell motility    04810 Regulation of actin cytoskeleton     124527565  09150 Organismal Systems   09151 Immune system    04625 C-type lectin receptor signaling pathway     124527565    04650 Natural killer cell mediated cytotoxicity     124527565    04660 T cell receptor signaling pathway     124527565    04662 B cell receptor signaling pathway     124527565    04664 Fc epsilon RI signaling pathway     124527565    04062 Chemokine signaling pathway     124527565   09152 Endocrine system    04910 Insulin signaling pathway     124527565    04929 GnRH secretion     124527565    04912 GnRH signaling pathway     124527565    04915 Estrogen signaling pathway     124527565    04917 Prolactin signaling pathway     124527565    04921 Oxytocin signaling pathway     124527565    04926 Relaxin signaling pathway     124527565    04935 Growth hormone synthesis, secretion and action     124527565    04919 Thyroid hormone signaling pathway     124527565    04916 Melanogenesis     124527565   09156 Nervous system    04725 Cholinergic synapse     124527565    04726 Serotonergic synapse     124527565    04720 Long-term potentiation     124527565    04730 Long-term depression     124527565    04722 Neurotrophin signaling pathway     124527565   09158 Development and regeneration    04360 Axon guidance     124527565   09149 Aging    04211 Longevity regulating pathway     124527565    04213 Longevity regulating pathway - multiple species     124527565   09159 Environmental adaptation    04714 Thermogenesis     124527565  09160 Human Diseases   09161 Cancer: overview    05200 Pathways in cancer     124527565    05206 MicroRNAs in cancer     124527565    05205 Proteoglycans in cancer     124527565    05207 Chemical carcinogenesis - receptor activation     124527565    05208 Chemical carcinogenesis - reactive oxygen species     124527565    05203 Viral carcinogenesis     124527565    05230 Central carbon metabolism in cancer     124527565    05231 Choline metabolism in cancer     124527565    05235 PD-L1 expression and PD-1 checkpoint pathway in cancer     124527565   09162 Cancer: specific types    05210 Colorectal cancer     124527565    05225 Hepatocellular carcinoma     124527565    05226 Gastric cancer     124527565    05214 Glioma     124527565    05216 Thyroid cancer     124527565    05221 Acute myeloid leukemia     124527565    05220 Chronic myeloid leukemia     124527565    05218 Melanoma     124527565    05211 Renal cell carcinoma     124527565    05219 Bladder cancer     124527565    05215 Prostate cancer     124527565    05213 Endometrial cancer     124527565    05224 Breast cancer     124527565    05223 Non-small cell lung cancer     124527565   09172 Infectious disease: viral    05166 Human T-cell leukemia virus 1 infection     124527565    05170 Human immunodeficiency virus 1 infection     124527565    05161 Hepatitis B     124527565    05160 Hepatitis C     124527565    05163 Human cytomegalovirus infection     124527565    05167 Kaposi sarcoma-associated herpesvirus infection     124527565    05165 Human papillomavirus infection     124527565   09171 Infectious disease: bacterial    05132 Salmonella infection     124527565   09164 Neurodegenerative disease    05010 Alzheimer disease     124527565    05022 Pathways of neurodegeneration - multiple diseases     124527565   09165 Substance dependence    05034 Alcoholism     124527565   09166 Cardiovascular disease    05417 Lipid and atherosclerosis     124527565   09167 Endocrine and metabolic disease    04933 AGE-RAGE signaling pathway in diabetic complications     124527565   09176 Drug resistance: antineoplastic    01521 EGFR tyrosine kinase inhibitor resistance     124527565    01522 Endocrine resistance     124527565  09180 Brite Hierarchies   09182 Protein families: genetic information processing    04131 Membrane trafficking [BR:lruf04131]     124527565   09183 Protein families: signaling and cellular processes    04147 Exosome [BR:lruf04147]     124527565    04031 GTP-binding proteins [BR:lruf04031]     124527565 Membrane trafficking [BR:lruf04131]  Exocytosis   Small GTPases and associated proteins    Other small GTPases and associated proteins     124527565  Endocytosis   Macropinocytosis    Ras GTPases     124527565 Exosome [BR:lruf04147]  Exosomal proteins   Exosomal proteins of other body fluids (saliva and urine)    124527565   Exosomal proteins of colorectal cancer cells    124527565 GTP-binding proteins [BR:lruf04031]  Small (monomeric) G-proteins   Ras Family    Ras [OT]     124527565 BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  Ras Roc Arf GTP_EFTU MMR_HSR1 RsgA_GTPase FeoB_N ATP_bind_1 Septin Ldh_1_N Motif Other DBs NCBI-GeneID:  124527565 NCBI-ProteinID:  XP_046956606 LinkDB All DBs Position Unknown AA seq 189 aa AA seqDB search MTEYKLVVVGAGGVGKSALTIQLIQNHFVDEYDPTIEDSYRKQVVIDGETCLLDILDTAG QEEYSAMRDQYMRTGEGFLCVFAINNTKSFEDIHQYREQIKRVKDSDDVPMVLVGNKCDL AARTVESRQAQDLARSYGIPYIETSAKTRQGVEDAFYTLVREIRQHKVRKLSPPDEGGPG CMSCKCLLS NT seq 570 nt NT seq  +upstreamnt  +downstreamnt atgacggaatataagctcgtggtggtgggcgctggaggtgtggggaagagtgccctgacc atccagctcatccagaaccacttcgtggacgagtatgaccccaccatcgaggactcctat cggaagcaagtggttatcgatggcgagacgtgcctactggacattttggacacggcgggc caggaggagtatagcgccatgcgggaccagtacatgcgcaccggagaaggcttcctctgt gtgtttgccatcaacaataccaagtcctttgaggacatccaccagtacagggagcaaatc aagcgagtgaaggactccgatgacgtgcccatggtgttggtggggaacaagtgtgacctg gccgcgcgcaccgtggagtcccggcaggcgcaggacctcgcccgcagctacggcatcccg tacattgagacgtcggccaagactcgccagggtgtggaggacgccttctacacgctggtc cgagagatccggcaacacaaggtgcggaagctgagcccgcccgacgagggtggccccggc tgcatgagctgcaagtgcctgctctcctga

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