Lynx rufus (bobcat): 124528633
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Entry
124528633 CDS
T08475
Name
(RefSeq) glutamate--cysteine ligase catalytic subunit isoform X1
KO
K11204
glutamate--cysteine ligase catalytic subunit [EC:
6.3.2.2
]
Organism
lruf
Lynx rufus (bobcat)
Pathway
lruf00270
Cysteine and methionine metabolism
lruf00480
Glutathione metabolism
lruf01100
Metabolic pathways
lruf01240
Biosynthesis of cofactors
lruf04216
Ferroptosis
Module
lruf_M00118
Glutathione biosynthesis, glutamate => glutathione
Brite
KEGG Orthology (KO) [BR:
lruf00001
]
09100 Metabolism
09105 Amino acid metabolism
00270 Cysteine and methionine metabolism
124528633
09106 Metabolism of other amino acids
00480 Glutathione metabolism
124528633
09140 Cellular Processes
09143 Cell growth and death
04216 Ferroptosis
124528633
Enzymes [BR:
lruf01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.2 glutamate---cysteine ligase
124528633
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Paralog
GFIT
Motif
Pfam:
GCS
GCS2
Motif
Other DBs
NCBI-GeneID:
124528633
NCBI-ProteinID:
XP_046958295
LinkDB
All DBs
Position
Unknown
AA seq
637 aa
AA seq
DB search
MGLLSQGSPLSWEETKRHADHVRRHGILQFLHIYHAVKDRHKDVLKWGDEVEYMLVSFDH
ENKRVQLVLSGEEVLETLQEKGERTNPNHPTLWRPEYGSYMIEGTPGQPYGGTMSEFNTV
EDNMRKRRKEATSLLGENQALCTITSFPRLGCPGFTLPEFKPNPLEGGASKSLFFPDEAI
NKHPRFSTLTRNIRHRRGEKVVINVPIFKDKNTPSPFMETFPEDEEAARASKPDHIYMDA
MGFGMGNCCLQVTFQACSISEARYLYDQLATICPIVMALSAASPFYRGYVSDIDCRWGVI
SASVDDRTREERGLEPLKNNSYRISKSRYDSIDSYLSECGEKYNDIDLTIDKEIYEQLLQ
EGIDHLLAQHVAHLFIRDPLTLFEEKIHLDDANESDHFENIQSTNWQTMRFKPPPPNSDI
GWRVEFRPMEVQLTDFENSAYVVFVVLLTRVILSYKLDFLIPLSKVDENMKVAQKRDAVL
RGMFYFRKDICKGGNTVVDGYGKVQNTSELTTEDYTLMSIDTIINGKEGVFPGLIPILNS
YLENMEVDVDTRCSILNYLKLIKKRASGELMTVARWMREFISNHPDYKRDSVITDEMNYS
LILKCNQIADELCECPELLGPAFRKVKYSGSKTDPSN
NT seq
1914 nt
NT seq
+upstream
nt +downstream
nt
atggggctgctgtcccagggctcgccgctgagctgggaggagaccaagcgccacgccgac
cacgtgcggcggcacgggatcctccagttcctgcacatctaccacgccgtcaaggaccgg
cacaaggacgtgctcaagtggggcgacgaggtggaatacatgttggtgtcttttgatcat
gaaaataagagagtccagttggtcctgtctggagaagaagttcttgaaactctacaagaa
aagggggaaaggacaaacccaaaccatcctaccctgtggagaccagagtatggcagttac
atgattgaaggcacacctggacaaccgtacggaggaactatgtccgagttcaacacagtt
gaagacaacatgagaaaacgccggaaggaggcgacctctttattaggagaaaatcaggct
ctttgcacaataacttcatttcccagattaggctgtcctgggttcacgctgccagagttt
aaacccaatccactcgaaggaggagcttccaagtccctcttctttcctgatgaagccata
aacaagcatccccgcttcagtaccctaacaagaaatatccgacacaggagaggagaaaag
gttgtcatcaatgtaccaatatttaaggacaagaatacaccatctccatttatggaaaca
tttcctgaggatgaggaggcagcaagggcttccaagcctgatcatatttacatggatgcc
atgggatttgggatgggtaattgctgtcttcaggtaacgttccaagcctgcagcatatct
gaggccagatacctttatgatcagctggccaccatctgtccaattgtcatggctttgagt
gctgcgtctcctttttaccgaggctatgtgtcagacattgattgtcgctggggagtgatt
tctgcatctgtagatgatagaactcgggaggagagaggactggagccactgaagaacaat
agctataggatcagtaaatcccgatatgattcaatagacagttacttatctgagtgtggg
gagaaatacaatgacatcgacttgacaattgataaagaaatctacgaacagctgctgcag
gaaggcattgatcatctcctggctcagcatgtcgctcatctcttcatcagagacccactg
actctatttgaagagaaaatacacttggatgatgccaatgaatcagaccattttgagaac
attcagtccacaaattggcagacaatgagatttaagccccctcctccaaactctgacatt
ggatggagagtagaattccgacccatggaggttcagttaacagactttgagaactctgca
tatgtggtgtttgtggtgctgcttacaagagtgatcctttcatacaaactggattttctc
attccactatcaaaggttgatgaaaacatgaaagttgcacagaaacgagatgctgtcttg
cggggaatgttttatttcaggaaagatatttgcaaaggtgggaacactgtggtggatggc
tacgggaaggtccagaacacttcagaactgaccacggaggactacaccctgatgagcata
gacaccatcatcaacgggaaggagggtgtgtttcctgggctgatcccaattctgaactct
taccttgaaaacatggaggtggatgtggacactagatgtagtattctgaactacctaaag
ctaattaagaagagagcatctggagaactaatgacagttgcccgatggatgagagagttt
atctcaaaccatcctgactataagcgagacagtgtaatcactgatgaaatgaactatagc
ctcatcttaaagtgtaaccaaattgcagacgaattgtgtgagtgcccggagttacttgga
ccagcgtttaggaaagtaaaatacagtggaagtaaaacggacccttccaactga
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