Ligilactobacillus salivarius JCM1046: LSJ_0340
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Entry
LSJ_0340 CDS
T03340
Symbol
murF
Name
(GenBank) UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase
KO
K01929
UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase [EC:
6.3.2.10
]
Organism
lsj
Ligilactobacillus salivarius JCM1046
Pathway
lsj00300
Lysine biosynthesis
lsj00550
Peptidoglycan biosynthesis
lsj01100
Metabolic pathways
lsj01502
Vancomycin resistance
Brite
KEGG Orthology (KO) [BR:
lsj00001
]
09100 Metabolism
09105 Amino acid metabolism
00300 Lysine biosynthesis
LSJ_0340 (murF)
09107 Glycan biosynthesis and metabolism
00550 Peptidoglycan biosynthesis
LSJ_0340 (murF)
09160 Human Diseases
09175 Drug resistance: antimicrobial
01502 Vancomycin resistance
LSJ_0340 (murF)
Enzymes [BR:
lsj01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.10 UDP-N-acetylmuramoyl-tripeptide---D-alanyl-D-alanine ligase
LSJ_0340 (murF)
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GFIT
Motif
Pfam:
Mur_ligase_M
Mur_ligase_C
Mur_ligase
Exop_C
HBS1_N
Motif
Other DBs
NCBI-ProteinID:
AIR10080
UniProt:
A0A089QBE1
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Position
372675..374045
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AA seq
456 aa
AA seq
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MKMQLAEVARALNIEAKEEWEDISITSVCFDSRKIESGALFIPLVAENDGHKYVEAAING
GAVATLWQEDHSENIPDSIAVLPVPDTLVALQQLGKHYLMKINPKVVAITGSNGKTTTKD
MTAAVLATQFNVHKTFANFNNEIGVPMTILSMEPNTEVLVVEMGMDRYGQLDFLSKLAEP
DVAVITMIGEAHIEFFGTRDHIADAKIEITHGLKEDGELVINGDEPLLTTKAKEVSQEVL
TFGSLDNNDMRAMDIVSDATKTSFKVATWPEVDFTINMIGAYNVFNALAALSVGNIYHIP
VDKMQKALASFDLTANRTEWLEAKNGAKILSDVYNSNPTAVKEVLYAFEQVPTEGKRIIV
LGDMLELGEKAAEMHSDLAQAINPDRIDSVYLCGELMGYLAEKLREKFDETQIHHYQKGD
LLTLTSDLKNELKADDIVLLKASHGIHLENVVSELI
NT seq
1371 nt
NT seq
+upstream
nt +downstream
nt
atgaaaatgcaattagccgaagtagcacgagcactcaatatcgaagctaaagaagaatgg
gaagatatttcaattacaagtgtttgcttcgatagccgtaaaatcgagtctggtgctttg
tttattcctttggtagctgaaaatgatggtcataagtatgtagaagctgcaatcaatggt
ggggcagttgctacactatggcaagaagatcattctgaaaatatcccagatagtattgca
gtattacctgttcctgatactttagttgctctacaacaattaggtaagcattatttaatg
aaaattaatcctaaagtagtagctattacaggaagtaacggaaaaactacaacaaaagat
atgacagcagcagtgttggctacacagttcaatgttcataagacttttgctaatttcaat
aatgaaattggagtacctatgacaatcttaagtatggaacctaatacagaagttctagta
gtagaaatgggtatggatcgttatggtcaattggattttttgagtaaattagctgaacct
gatgttgcagtaattactatgattggtgaagcgcatatagaattctttggaacaagagat
catattgctgacgctaagatagaaattacacatggtttaaaagaagatggagaattggta
attaatggtgacgaaccattattaactacaaaagctaaagaagttagtcaagaagtacta
acctttggtagccttgataataatgatatgcgtgcaatggatattgttagtgatgctact
aagacaagttttaaagtagcaacttggcctgaagtagatttcacgatcaatatgattggt
gcatataatgttttcaatgctttagcagctttaagtgtgggtaatatttatcatatacca
gtagataagatgcaaaaagctttagcatcatttgatttaacagctaatcgaacagaatgg
ttagaagctaaaaatggtgcaaagattttgagcgatgtatataattcaaatccaacagca
gttaaagaagttttatacgcttttgaacaagttccaactgaaggaaagagaattattgtt
ctaggtgatatgcttgaattaggtgagaaagctgctgaaatgcacagtgatttagcccaa
gctattaatcctgatagaatagacagtgtctatctatgtggagaacttatggggtattta
gctgaaaaattaagagagaaatttgatgaaactcaaattcatcactatcagaaaggtgat
ttattaacattaacttctgatttaaaaaatgaattaaaggcagatgacattgttttatta
aaagctagtcacggaattcatttggaaaacgttgtaagtgaattaatttaa
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