Ligilactobacillus salivarius UCC118: LSL_0355
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Entry
LSL_0355 CDS
T00337
Symbol
murF
Name
(GenBank) UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase
KO
K01929
UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase [EC:
6.3.2.10
]
Organism
lsl
Ligilactobacillus salivarius UCC118
Pathway
lsl00300
Lysine biosynthesis
lsl00550
Peptidoglycan biosynthesis
lsl01100
Metabolic pathways
lsl01502
Vancomycin resistance
Brite
KEGG Orthology (KO) [BR:
lsl00001
]
09100 Metabolism
09105 Amino acid metabolism
00300 Lysine biosynthesis
LSL_0355 (murF)
09107 Glycan biosynthesis and metabolism
00550 Peptidoglycan biosynthesis
LSL_0355 (murF)
09160 Human Diseases
09175 Drug resistance: antimicrobial
01502 Vancomycin resistance
LSL_0355 (murF)
Enzymes [BR:
lsl01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.10 UDP-N-acetylmuramoyl-tripeptide---D-alanyl-D-alanine ligase
LSL_0355 (murF)
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GFIT
Motif
Pfam:
Mur_ligase_M
Mur_ligase_C
Mur_ligase
Exop_C
HBS1_N
Motif
Other DBs
NCBI-ProteinID:
ABD99168
UniProt:
Q1WV17
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All DBs
Position
387857..389227
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AA seq
456 aa
AA seq
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MKMQLAEVARALNIEAKEEWEDISITSVCFDSRKIESGALFIPLVAENDGHKYVEAAING
GAVATLWQEDHSENIPDSIAVLPVSDTLVALQQLGKHYLMKINPKVVAITGSNGKTTTKD
MTAAVLATQFNVHKTFANFNNEIGVPMTILSMEPNTEVLVVEMGMDRYGQLDFLSKLAEP
DVAVITMIGEAHIEFFGTRDHIADAKMEITHGLKEDGELVINGDEPLLTTKAKEVSQEVL
TFGSLDNNDMCAMDIVSDATKTSFKVATWPEVDFTINMIGAYNVFNALAALSVGNIYHIP
VDKMQKALASFDLTANRTEWLEAKNGAKILSDVYNSNPTAVKEVLYAFEQVPTEGKRIIV
LGDMLELGEKAAEMHSNLAQAINPDRIDSVYLCGELMGHLAEKLREKFDETQIHHYQKDD
LLTLTSDLKNELMSDDIVLLKASHGIHLENVVSELI
NT seq
1371 nt
NT seq
+upstream
nt +downstream
nt
atgaaaatgcaattagccgaagtagcacgagcactcaatatcgaagctaaagaagaatgg
gaagatatttcaattacaagtgtttgcttcgatagccgtaaaatcgagtctggtgctttg
tttattcctttggtggctgaaaatgatggtcataagtatgtagaagctgcaatcaatggt
ggggcagttgctacactatggcaagaagatcattctgaaaatatcccagatagtattgca
gtattacctgtttctgatactttagttgctctacaacaattaggtaagcattatttaatg
aaaattaatcctaaagtagtagctattacaggaagtaacggaaaaactacaacaaaagat
atgacagcagcagtgttggctacacagttcaatgttcataagacttttgctaatttcaat
aatgaaattggagtacctatgacaatcttaagtatggaacctaatacagaagttctagta
gtggaaatgggtatggatcgttatggtcaattggactttttgagtaaattagctgaacct
gatgttgcagtaattactatgattggtgaagcgcatatagaattctttggaacaagagat
catattgctgacgctaagatggaaattacacatggtttaaaagaagatggagaattggta
attaatggtgacgaaccattattgactacaaaagctaaagaagttagtcaagaagtacta
acctttggtagccttgataataatgatatgtgtgcaatggatattgttagtgatgctact
aagacaagttttaaagtagcaacttggcctgaagtagatttcacgatcaatatgattggt
gcatataatgttttcaatgctttagcagctttaagtgtgggtaatatttatcatatacca
gtagataagatgcaaaaagctttagcatcatttgacttaacagccaatcgaacagaatgg
ctagaagctaaaaatggtgcaaaaattttgagcgatgtatataattcaaatccaacagca
gttaaagaagttttatacgcttttgaacaagttccaactgaaggaaagagaattattgtt
ctaggtgatatgcttgaattaggtgagaaagctgctgaaatgcacagtaatttagcccaa
gctattaatcctgatagaatagacagtgtttatctatgtggagaattaatgggacattta
gctgaaaaattaagagagaaatttgatgaaactcaaattcatcactatcaaaaagatgat
ttactaactttaacttctgatttaaaaaatgaattaatgtctgatgatattgttttatta
aaagctagtcacggaattcatttggaaaacgttgtaagtgaattaatttaa
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