Lactuca sativa (garden lettuce): 111904148
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Entry
111904148 CDS
T05352
Name
(RefSeq) 2-oxoisovalerate dehydrogenase subunit alpha 2, mitochondrial isoform X1
KO
K00166
2-oxoisovalerate dehydrogenase E1 component subunit alpha [EC:
1.2.4.4
]
Organism
lsv
Lactuca sativa (garden lettuce)
Pathway
lsv00280
Valine, leucine and isoleucine degradation
lsv00640
Propanoate metabolism
lsv00785
Lipoic acid metabolism
lsv01100
Metabolic pathways
lsv01110
Biosynthesis of secondary metabolites
lsv01210
2-Oxocarboxylic acid metabolism
Module
lsv_M00036
Leucine degradation, leucine => acetoacetate + acetyl-CoA
Brite
KEGG Orthology (KO) [BR:
lsv00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00640 Propanoate metabolism
111904148
09105 Amino acid metabolism
00280 Valine, leucine and isoleucine degradation
111904148
09108 Metabolism of cofactors and vitamins
00785 Lipoic acid metabolism
111904148
Enzymes [BR:
lsv01000
]
1. Oxidoreductases
1.2 Acting on the aldehyde or oxo group of donors
1.2.4 With a disulfide as acceptor
1.2.4.4 3-methyl-2-oxobutanoate dehydrogenase (2-methylpropanoyl-transferring)
111904148
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Motif
Pfam:
E1_dh
DXP_synthase_N
TPP_enzyme_C
Motif
Other DBs
NCBI-GeneID:
111904148
NCBI-ProteinID:
XP_023755689
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All DBs
Position
1:11843162..11848530
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AA seq
486 aa
AA seq
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MAIWLASRKGADYFTKTLISTTFRSLRTSTTVIASFRDSDDSSTGSFRKPYLFFPCADSS
PSAVFRSRRFESSQAGPQLDFFSSDDDDEQIQGSMDFPGGKIGFTSEMRFLPESSEKRVQ
CYRVLDDNGYELSSPKQHMNKEVAMKMYSGMLTLDSLDTVLYEAQRQGRISFYVTSFGEE
AINLASAAALSSDDLIMPQYREPGILWWRGFTLQEFVNQCFGNKNDYGKGRQMPIHYGSK
KHNYFTVSSPLATQLPQAVGAAYSLKAEKKDACVVAFFGDGSSSEGDFHASLNFAAVLEA
PVVFICRNNGWAISTPTTDQFRSDGIVVKGHGYGIRSIRVDGNDALAVYNVVRVAREMAV
TEQRPILIEAMTYRVGHHSTSDDSTKYRPADEIEHWKTSRNPVSIFRKWVQRKGWWSDEQ
ESEFRADIRKQVINAIQVAEKTEKPSLENMFTDVYEELPSSLKDQERLIRNTIKRHPQDY
PTDVPL
NT seq
1461 nt
NT seq
+upstream
nt +downstream
nt
atggcaatatggctggccagtagaaaaggcgccgattatttcaccaaaacattgatatcc
accactttcagatcattacgaacttccactactgttattgcttccttccgtgattccgat
gacagcagcaccgggagcttcagaaagccttatttattctttccgtgcgccgattcatca
ccgtcggccgttttcagatctcgccgctttgaatcctcgcaagctgggccacaattggat
ttcttctctagcgatgatgacgacgaacaaattcagggtagtatggatttccctggtggt
aaaattgggttcacttctgaaatgaggtttcttccggagtcatctgagaagcgagtgcaa
tgttatcgagttcttgatgataacggctatgagctttcatctcccaaacaacatatgaat
aaggaagttgcaatgaagatgtatagtggcatgttgacacttgacagtttggatacggtt
ttgtatgaagcacaaaggcaaggaagaatatcgttttatgttacttcatttggtgaagaa
gctatcaatctagcatcagcagcagcactttcctccgatgatctcattatgccacagtat
cgagaaccaggaatcttgtggtggagaggttttacattgcaagaatttgtgaatcaatgc
tttggaaacaagaatgattatgggaaaggaagacaaatgccgattcattatggatccaag
aagcacaattacttcactgtctcatcacctttagcgacacaacttcctcaagccgttggt
gctgcatactctctaaaagcagagaaaaaagatgcatgtgtcgttgccttttttggtgat
ggcagttcaagtgagggagatttccatgcaagtttaaactttgcggcggttttggaagcc
ccggttgttttcatttgtcgcaataatggatgggctattagcactcctaccacagatcaa
tttcgaagtgatggaattgttgtgaagggacacgggtatggtatccgaagtatcagagtg
gatggaaatgatgctctcgcggtctataatgtagtacgcgtggcccgtgaaatggctgtc
accgaacaacgaccgatactaatcgaggctatgacttatagagtaggacatcactcgaca
tctgatgattcaacaaagtatcggcccgcagatgaaattgaacactggaaaacatcgcga
aacccggtatccatttttaggaaatgggttcagagaaaaggttggtggagtgatgaacaa
gaatctgaatttcgagccgacattagaaagcaggtgataaatgcaattcaagtagcggaa
aaaacagagaagccatcacttgaaaatatgtttactgatgtgtatgaagagttaccttca
agtctaaaggatcaagagagattgattagaaatactataaaaagacacccacaagactat
ccaacagatgtacctttatga
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