Lipotes vexillifer (Yangtze River dolphin): 103072653
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Entry
103072653 CDS
T03090
Symbol
NF1
Name
(RefSeq) neurofibromin isoform X1
KO
K08052
neurofibromin 1
Organism
lve
Lipotes vexillifer (Yangtze River dolphin)
Pathway
lve01521
EGFR tyrosine kinase inhibitor resistance
lve04010
MAPK signaling pathway
lve04014
Ras signaling pathway
Brite
KEGG Orthology (KO) [BR:
lve00001
]
09130 Environmental Information Processing
09132 Signal transduction
04010 MAPK signaling pathway
103072653 (NF1)
04014 Ras signaling pathway
103072653 (NF1)
09160 Human Diseases
09176 Drug resistance: antineoplastic
01521 EGFR tyrosine kinase inhibitor resistance
103072653 (NF1)
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
PH_NF1
RasGAP
CRAL_TRIO_2
CRAL_TRIO
MIF4G_like_2
Motif
Other DBs
NCBI-GeneID:
103072653
NCBI-ProteinID:
XP_007452453
UniProt:
A0A340WSG9
LinkDB
All DBs
Position
Unknown
AA seq
2841 aa
AA seq
DB search
MAAHRPVEWVQAVVSRFDEQLPIKTGQQNTHTKVSTEHNKECLINISKYKFSLVISGLTT
ILKNVNNMRIFGEAAEKNLYLSQLIILDTLEKCLAGQPKDTMRLDETMLVKQLLPEICHF
LHTCREGNQHAAELRNSASGVLFSLSCNNFNAVFSRISTRLQELTVCSEDNVDVHDIELL
QYINVDCAKLKRLLKETAFKFKALKKVAQLAVINSLEKAFWNWVENYPDEFTKLYQIPQT
DMAECAEKLFDLVDGFAESTKRKAAVWPLQIILLILCPEIIQDISKDVVDENNMNKKLFL
DSLRKALAGHGGSRQLTESAAIACVKLCKASTYINWEDNSVIFLLVQSMVVDLKNLLFNP
SKPFSRGSQPADVDLMIDCLVSCFRISPHNNQHFKICLAQNSPSTFHYVLVNSLHRIITN
SALDWWPKIDAVYCHSVELRNMFGETLHKAVQGCGAHPAIRMAPSLTFKEKVTSLKFKEK
PTDLETRSYKYLLLSMVKLIHADPKLLLCNPRKQGPETQGSTAELITGLVQLVPQSHMPE
IAQEAMEALLVLHQLDSIDLWNPDAPVETFWEISSQMLFYICKKLTSHQMLSSTEILKWL
REILICRNKFLLKNKQADRSSCHFLFLYGVGCDVSSSGNTSQVSIDHEELLRTCTPGTSL
RKGKGNSSMDSAAGYSGTPPICRQAQTKLEVALYMFLWSPDTEAVLVAMSCFRHLCEEAD
IRCGVDEVSVHNFLPNYNTFMEFASVSNMMSTGRAALQKRVMALLRRIEHPTAGNTEAWE
DTHAKWEQATKLILNYPKAKMEDGQAAESLHKTIVKRRMSHVSGGGSIDLSDTDSLQEWI
NMTGFLCALGGVCLQQRSNSGLATYSPPMGPVSERKGSMISVMSSEGNADTPVSKFMDRL
LSLMVCNHEKVGLQIRTNVKDLVGLELSPALYPMLFNKLKNTISKFFDSQGQVLLTDTNT
QFVEQTIAIMKNLLDNHTEGSSEHLGQASIETMMLNLVRYVRVLGNMVHAIQIKTKLCQL
VEVMMARRDDLSFCQEMKFRNKMVEYLTDWVMGTSNQAADDDVKCLTRDLDQASMEAVVS
LLAGLPLQPEEGDGVELMEAKSQLFLKYFTLFMNLLNDCSEVEDENAQTGGRKRGMSRRL
ASLRHCTVLAMSNLLNANVDSGLMHSIGLGYHKDLQTRATFMEVLTKILQQGTEFDTLAE
TVLADRFERLVELVTMMGDQGELPIAMALANVVPCSQWDELARVLVTLFDSRHLLYQLLW
NMFSKEVELADSMQTLFRGNSLASKIMTFCFKVYGATYLQKLLDPLLRIVITSSDWQHVS
FEVDPTRLEQSESLEENQRNLLQMTEKFFHAIISSSSEFPPQLRSVCHCLYQATCHSLLN
KATVKEKKENKKSVVSQRFPQNSIGAVGSAMFLRFINPAIVSPYEAGILDKKPPPRIERG
LKLMSKVLQSIANHVLFTKEEHMRPFNDFVKSNFDAARRFFLDIASDCPTSDAVNHSLSF
ISDGNVLALHRLLWNNQEKIGQYLSSNRDHKAVGRRPFDKMATLLAYLGPPEHKPVADTH
WSSLNLTSSKFEEFMTRHQVHEKEEFKALKTLSIFYQAGTSKAGNPIFYYVARRFKTGQI
NGDLLIYHVLLTLKPYYAKPYEIVVDLTHTGPSNRFKTDFLSKWFVVFPGFAYDNVSAVY
IYNCNSWVREYTKYHERLLTGLKGSKRLIFIDCPGKLAEHIEHEQQKLPAATLALEEDLK
VFHNALKLAHKDTKVSIKVGSTAVQVTSAERTKVLGQSVFLNDIYYASEIEEICLVDENQ
FTLTIANQGTPLTFMHQECEAIVQSIIHIRTRWELSQPDSIPQHTKIRPKDVPGTLLNIA
LLNLGSSDPSLRSAAYNLLCALTCTFNLKIEGQLLETSGLCIPANNTLFIVSISKTLAAN
EPHLTLEFLEECISGFSKSSIELKHLCLEYMTPWLSNLVRFCKHNDDAKRQRVTAILDKL
ITMTINEKQMYPSIQAKIWGSLGQITDLLDVVLDSFIKTSATGGLGSIKAEVMADTAVAL
ASGNVKLVSSKVIGRMCKIIDKTCLSPTPTLEQHLMWDDIAILARYMLMLSFNNSLDVAA
HLPYLFHVVTFLVATGPLSLRASTHGLVINIIHSLCTCSQLHFSEETKQVLRLSLTEFSL
PKFYLLFGISKVKSAAVIAFRSSYRDRSFSPGSYERETFALTSLETVTEALLEIMEACMR
DIPTCKWLDQWTELAQRFAFQYNPSLQPRALVVFGCISKRVSHGQIKQIIRILSKALESC
LKGPDTYNSQVLIEATVIALTKLQPLLNKDSPLHKALFWVAVAVLQLDEVNLYSAGTALL
EQNLHTLDSLRIFNDKSPEEVFMAIRNPLEWHCKQMDHFVGLNFNSNFNFALVGHLLKGY
RHPSPAIVARTVRILHTLLTLVNKHRNCDKFEVNTQSVAYLAALLTVSEEVRSRCSLKHR
KSLLLTDISVENIPMDTYPIHHGDPSYRTLKESQPWSSPKGSEGYLAASYPPAGQTSPRA
RKSMSLDMGQPSQANTKKLLGTRKSFDHLISDTKAPKRQEMESGITTPPKMRRVAETDYE
METQRISSSQQHPHLRKVSVSESNVLLDEEVLTDPKIQALLLTVLATLVKYTTDEFDQRI
LYEYLAEASVVFPRVFPVVHNLLDSKINTLLSLCQDPNLLNPIHGIVQSVVYHEESPPQY
QTSYLQSFGFNGLWRFAGPFSKQTQIPDYAELIVKFLDALIDTYLPGIDEETSEESLLTP
TSPYPPAVQSQLSITANLNLSNSMTSLATSQHSPGIDKENVELSPTTGHCNSGRTRHGSA
SQVQKQRSAGSFKRNSIKKIV
NT seq
8526 nt
NT seq
+upstream
nt +downstream
nt
atggccgcgcataggccggtggaatgggtccaggccgtggtcagccgcttcgacgagcag
cttccaataaaaacaggacagcagaatacacataccaaagtcagtaccgaacacaacaag
gaatgtcttatcaatatttccaaatacaagttttctttggttataagcggcctcaccact
atcttaaagaatgttaacaatatgagaatatttggagaagctgctgaaaaaaatttatat
ctctctcagttgattatattggatacactggaaaaatgtcttgctgggcaaccaaaggac
acgatgaggttagatgaaacgatgctggtcaaacagttgctgccagaaatctgccatttt
cttcacacttgtcgtgagggaaaccaacatgcagctgaacttcggaattctgcctctggg
gttttattttctctcagctgcaacaacttcaatgcagtctttagtcgaatttctaccagg
ttacaggaattgactgtttgttcagaagacaatgttgatgttcatgatatagaattgtta
cagtatatcaatgtggattgtgcaaaattaaaacgactcctgaaggaaacagcatttaaa
tttaaagccctaaagaaagttgcacaattagcagttataaatagcctggaaaaagcattt
tggaactgggtagaaaattatccagatgaatttacaaagttataccagattccacagact
gatatggctgagtgtgcagaaaaactctttgacctagtggatggttttgctgaaagcacc
aaacgtaaagcagcagtttggccactacaaatcattctccttatcttgtgtccagaaata
atccaggatatatccaaggatgtggttgatgaaaacaacatgaataagaagttgtttctg
gacagtctacgaaaagcacttgccggccacggaggaagcaggcagctgactgaaagcgct
gcaattgcctgtgtcaaactgtgtaaagcaagtacttacatcaattgggaagataactct
gtcatcttcttactagttcagtccatggtggttgatcttaagaacctgctttttaatcca
agtaaaccattctcaagaggcagtcagcctgcagatgtggatctaatgattgactgcctt
gtttcttgctttcgtataagccctcacaacaaccaacactttaagatctgtctggctcag
aattccccttctacatttcactatgtgctggtaaattcactccatcgaatcatcaccaat
tctgcattggattggtggcctaagattgatgccgtatattgtcactcagttgaacttcga
aatatgtttggtgaaacacttcataaagcagtccagggttgtggagcgcacccagcaata
cgaatggcaccgagtcttacatttaaagaaaaagtaacaagccttaaatttaaagaaaaa
cctacagacctggagacaagaagctataagtatcttctcttgtccatggtgaaactaatt
catgcagatccaaagctcttgctttgtaatccgagaaaacaggggcctgaaactcaaggc
agtaccgcagaattaattacagggctcgtccaactggttcctcagtcacacatgccagag
attgctcaggaagcaatggaggctctgttggttcttcaccagttagatagcattgatttg
tggaatcctgatgctcctgtagaaacattttgggaaatcagctcacaaatgcttttttac
atctgcaagaaattaactagccatcaaatgcttagtagcacagaaattctcaaatggttg
cgggaaattttgatctgcaggaataaatttcttcttaaaaataagcaggcagatagaagt
tcctgtcactttctcttcctttatggagtaggatgtgatgtttcttcaagtggaaatacc
agtcaggtgtccatagatcatgaagaattactacgtacttgtactcctggaacctctctc
cgaaagggaaaaggaaattcatccatggatagtgcagcagggtacagtggaaccccgcca
atatgccgacaagcccagaccaaactagaagtggccctgtacatgtttctgtggagccct
gacactgaagctgttctggttgccatgtcctgttttcgtcacctctgtgaggaagcggat
atccggtgtggggtggatgaagtgtcagtgcacaacttcttgcccaactataacacattc
atggagtttgcctctgtcagcaatatgatgtcaacaggaagagcagcacttcagaaaaga
gtgatggcattactacggcgaattgagcatcccaccgcaggaaacactgaggcttgggaa
gatacacatgcaaagtgggaacaagctacaaaactaatcctcaactacccaaaagccaaa
atggaagatggccaggctgctgaaagccttcacaagaccatcgttaagaggcgaatgtct
catgtgagtggaggaggatccatagatttgtctgacacagactccctacaagaatggatc
aacatgactggcttcctttgtgcccttgggggagtatgcctgcagcagagaagcaattct
ggcctggcaacctatagcccacccatgggcccagtcagtgaacgcaagggttccatgatt
tcagtgatgtcctcagagggaaatgcagatacacctgtcagcaaatttatggatcggctg
ctatccttaatggtctgtaaccatgagaaagtgggacttcagatacggaccaatgttaag
gatctggtgggtctagaattgagtcctgctctttatccaatgctctttaacaaactgaag
aataccatcagcaagttttttgactcccaagggcaggttttattgactgacaccaatact
cagttcgtggagcaaaccatagctataatgaagaacttactagataatcatactgaaggc
agctctgaacatctggggcaagctagcattgaaacaatgatgttaaatctggtcagatat
gttcgtgtgcttgggaatatggtccatgcaattcaaataaaaacgaaactgtgtcagtta
gtggaggtaatgatggcaaggagagatgacctctcattttgtcaagagatgaaatttagg
aataagatggtagaatacctgacagattgggttatgggaacgtcaaaccaagcagcagat
gatgatgtaaaatgtcttacaagagatttggatcaggcaagcatggaagcagtagtttca
ctcctggctggtcttccgctgcagcctgaggaaggagatggtgtggaattgatggaagcc
aaatcacagttatttcttaagtatttcacattgtttatgaaccttttgaacgactgtagt
gaagttgaagatgaaaatgcacaaacaggtggcaggaaacgtggcatgtctcggaggctg
gcatcactgaggcactgtacagtcctggcaatgtcaaacttactcaatgctaacgtggac
agtggcctcatgcactccataggtttaggttatcacaaagatctccagacaagagctaca
tttatggaagttctgacaaaaatccttcaacaaggcacagaatttgacacacttgcagaa
acggtgttggcagatcgttttgagagactggtagagttggtcacaatgatgggtgatcaa
ggagagctcccaatagctatggctctggccaatgtggtcccttgttctcagtgggatgaa
ctagctcgagttctagtgactctatttgactctcggcatttactctaccaactgctctgg
aacatgttttctaaggaagtagaattggcagactccatgcagactcttttccgaggcaac
agcttggccagtaaaataatgaccttctgtttcaaggtatatggtgctacctacctacag
aaactcctggatcctttattacggattgtgatcacatcctctgattggcagcatgttagc
tttgaagtagatcctaccaggttagaacagtcagagagccttgaggaaaaccagcgaaac
ctccttcagatgaccgaaaagttcttccatgccatcatcagttcctcctccgaatttccc
cctcagctacgaagtgtgtgccactgtttgtaccaggcaacttgccactccctactgaat
aaagctacagtaaaagaaaaaaaggaaaacaaaaaatcagtggttagccagcgtttccct
cagaacagcatcggtgcagtgggaagtgccatgtttctcagatttatcaatcctgccatt
gtctcaccatatgaagcagggattttagataaaaagccaccacctagaatcgaaagaggc
ttgaagttaatgtcaaaggtacttcagagtattgccaatcatgtccttttcacaaaagaa
gagcacatgcggccttttaatgattttgtgaaaagcaactttgatgcagcacgaaggttt
ttccttgatatagcatccgattgtcctacaagtgatgcagtaaatcatagtctttccttc
atcagtgatggcaatgtgcttgctttacatcgtctgctctggaacaatcaagagaaaatt
ggccagtatctttccagcaacagggatcacaaagctgttggaagacgaccttttgataag
atggcaacacttcttgcatacctgggtcctccagagcacaaacctgtggcagatacacac
tggtccagccttaaccttaccagttcaaagtttgaggaatttatgactaggcatcaagta
cacgaaaaagaagagttcaaagctttgaaaactttaagtattttctaccaagctgggact
tccaaagctgggaatcctatattttattatgttgcacggaggttcaaaactggtcaaatc
aatggcgatttgctgatataccacgtcttacttactttaaagccatattatgcaaagcca
tacgaaattgtagtggaccttacccatactgggcctagcaatcgctttaaaacagacttc
ctctccaagtggtttgttgtttttcctggctttgcttatgataatgtctctgcagtctat
atctataactgtaactcctgggtcagggaatataccaagtatcacgagcggctgctgact
ggcctcaaaggcagcaaaagactcattttcatagactgtcctgggaaactggccgagcac
attgagcatgaacagcagaaactacccgctgccaccttggctttagaagaggacctgaag
gtattccacaatgctctcaagctagctcacaaagacacaaaggtttctattaaagttggt
tctactgctgttcaagtaacctcagcagagcgaacaaaagtcctggggcagtcagtcttt
ctaaatgatatctattatgcttcggaaattgaagagatctgcctagtggatgagaaccag
ttcaccttaactattgcaaaccagggcacaccactgaccttcatgcaccaggagtgtgaa
gccattgttcagtctatcattcacatccggacacgttgggagctgtcgcagcctgactcc
atcccccagcacaccaagattcgcccaaaagatgtccctgggacactgctcaatatcgca
ttacttaatttaggcagttcagaccctagtttacggtcagctgcctataatcttctgtgt
gccttaacttgtacctttaatttaaaaatcgagggccagttactagagacatcaggttta
tgtatcccagccaacaacaccctatttattgtctctattagtaagacactggcagccaat
gagccacacctcaccttagaatttttggaagagtgtatttctggatttagcaaatctagt
attgaattgaaacacctttgtttggaatacatgactccatggctgtcaaatctagtacgt
ttttgtaagcacaatgatgatgccaaaagacaaagagttactgcgattcttgataagctg
ataacaatgactataaacgagaaacagatgtatccatctattcaagcaaaaatatggggg
agccttgggcagattacagacctccttgatgttgtactagacagtttcatcaaaaccagt
gcaacgggtggcttgggatcaataaaagctgaggtgatggcagatactgctgtagctttg
gcttctggaaatgtgaaattggtttcaagcaaggttattggaaggatgtgcaaaataatt
gacaagacatgcttatctccaactcctactttagagcaacatcttatgtgggacgatatt
gctattctagcccgctacatgctgatgctgtccttcaacaattccctggacgtggcagct
catctcccctacctcttccacgtcgttactttcttagtagccacagggccactctccctt
agagcttccacacatggattggtcattaatatcattcactctctgtgtacttgttctcag
cttcattttagtgaagagaccaagcaagttttgagactcagtttgacagagttctcatta
cccaaattttacctgctgtttggcattagcaaagtcaagtcagctgctgtcattgccttc
cgctccagctaccgggacaggtcattctctcctggctcctatgagagggagacttttgca
ttgacgtccttggaaacggtcacagaagctttgttggagatcatggaggcatgtatgaga
gatattccaacatgcaagtggctggaccagtggacagaactagctcaaagatttgcattc
caatataatccatccctgcaaccaagagctcttgttgtctttggctgtattagcaaacga
gtgtctcatgggcagataaagcagattatccgtattctcagcaaggcgcttgagagttgc
ttaaaaggacctgatacttacaacagtcaagttctgatagaagccacagtaatagcacta
accaaattacaaccacttcttaataaggactcccctctgcataaagccctcttttgggta
gctgtggccgtgctgcagctcgatgaagtcaatttgtattcagcgggcaccgcacttctg
gaacaaaacctgcacaccttagacagtctccggatattcaatgacaagagtccagaggaa
gtattcatggcgatccggaatcctctggaatggcactgcaaacaaatggatcattttgtt
ggactcaatttcaactctaactttaacttcgcactggttggacacctcttaaaaggatac
aggcatccttcacctgccattgttgcaagaacagtcagaattttgcatacactactaact
ctggttaataaacatagaaattgtgacaaatttgaggtgaatacacagagcgtggcttac
ttggcagctttacttacagtgtctgaggaggttcgaagtcgctgtagcctaaaacataga
aagtctcttcttcttactgatatttcagtggaaaatattcctatggatacatatcccatt
catcatggtgaccctagctataggacactaaaggagagtcagccatggtcctctcccaaa
ggttctgaagggtaccttgcagccagctatccacctgcgggccagaccagtccccgagcc
aggaaatccatgagtttggacatggggcagccttctcaggccaacacgaagaagttgctt
ggaacaaggaaaagttttgatcacttgatatcagacacaaaggctcctaaaaggcaagaa
atggaatcagggatcacaacaccccccaaaatgaggagagtagcagaaactgattatgaa
atggaaactcaaaggatttcctcatcacaacagcacccacatttacgtaaagtttcagtg
tctgaatcaaatgttctcttagatgaagaagtacttactgatccgaagatccaagcactt
cttcttactgttctggctacgctggtgaaatacaccacggatgagtttgatcaacgaatt
ctttatgaatatttagcagaagctagtgttgttttccccagagtttttcctgttgtgcac
aatttgttggactctaagatcaacaccctgttgtcattgtgccaagatccaaatttgtta
aatccaatccatgggattgtgcaaagtgtggtgtaccatgaagaatccccaccacagtac
caaacatcttacctgcaaagttttggttttaatggcctgtggcggtttgcaggacccttt
tcaaagcaaacacaaatcccagactatgctgagcttattgttaagtttcttgatgccttg
attgacacgtatttgcctggaattgatgaagaaaccagtgaggagtccctcctgacaccc
acatctccttatcctcctgcagtgcagagccagcttagtattactgctaaccttaacctt
tctaattccatgacctcacttgcaacttcccagcattccccaggaatcgacaaggagaat
gttgaactctcccctaccactgggcactgtaacagtgggcgaactcgtcatggatccgca
agccaggtgcagaagcaaagaagcgctggcagtttcaaacgtaatagcattaagaagatc
gtgtga
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integrated database retrieval system
