Lipotes vexillifer (Yangtze River dolphin): 103075672
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Entry
103075672 CDS
T03090
Symbol
ERBB2
Name
(RefSeq) receptor tyrosine-protein kinase erbB-2
KO
K05083
receptor tyrosine-protein kinase erbB-2 [EC:
2.7.10.1
]
Organism
lve
Lipotes vexillifer (Yangtze River dolphin)
Pathway
lve01521
EGFR tyrosine kinase inhibitor resistance
lve01522
Endocrine resistance
lve01524
Platinum drug resistance
lve04010
MAPK signaling pathway
lve04012
ErbB signaling pathway
lve04020
Calcium signaling pathway
lve04066
HIF-1 signaling pathway
lve04151
PI3K-Akt signaling pathway
lve04510
Focal adhesion
lve04518
Integrin signaling
lve04520
Adherens junction
lve04530
Tight junction
lve05200
Pathways in cancer
lve05205
Proteoglycans in cancer
lve05206
MicroRNAs in cancer
lve05212
Pancreatic cancer
lve05213
Endometrial cancer
lve05215
Prostate cancer
lve05219
Bladder cancer
lve05223
Non-small cell lung cancer
lve05224
Breast cancer
lve05226
Gastric cancer
lve05230
Central carbon metabolism in cancer
Brite
KEGG Orthology (KO) [BR:
lve00001
]
09130 Environmental Information Processing
09132 Signal transduction
04010 MAPK signaling pathway
103075672 (ERBB2)
04012 ErbB signaling pathway
103075672 (ERBB2)
04066 HIF-1 signaling pathway
103075672 (ERBB2)
04020 Calcium signaling pathway
103075672 (ERBB2)
04151 PI3K-Akt signaling pathway
103075672 (ERBB2)
09133 Signaling molecules and interaction
04518 Integrin signaling
103075672 (ERBB2)
09140 Cellular Processes
09144 Cellular community - eukaryotes
04510 Focal adhesion
103075672 (ERBB2)
04520 Adherens junction
103075672 (ERBB2)
04530 Tight junction
103075672 (ERBB2)
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
103075672 (ERBB2)
05206 MicroRNAs in cancer
103075672 (ERBB2)
05205 Proteoglycans in cancer
103075672 (ERBB2)
05230 Central carbon metabolism in cancer
103075672 (ERBB2)
09162 Cancer: specific types
05212 Pancreatic cancer
103075672 (ERBB2)
05226 Gastric cancer
103075672 (ERBB2)
05219 Bladder cancer
103075672 (ERBB2)
05215 Prostate cancer
103075672 (ERBB2)
05213 Endometrial cancer
103075672 (ERBB2)
05224 Breast cancer
103075672 (ERBB2)
05223 Non-small cell lung cancer
103075672 (ERBB2)
09176 Drug resistance: antineoplastic
01521 EGFR tyrosine kinase inhibitor resistance
103075672 (ERBB2)
01524 Platinum drug resistance
103075672 (ERBB2)
01522 Endocrine resistance
103075672 (ERBB2)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
lve01001
]
103075672 (ERBB2)
09183 Protein families: signaling and cellular processes
04147 Exosome [BR:
lve04147
]
103075672 (ERBB2)
04090 CD molecules [BR:
lve04090
]
103075672 (ERBB2)
Enzymes [BR:
lve01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.10 Protein-tyrosine kinases
2.7.10.1 receptor protein-tyrosine kinase
103075672 (ERBB2)
Protein kinases [BR:
lve01001
]
Receptor tyrosine kinases (RTK)
EGFR family [OT]
103075672 (ERBB2)
Exosome [BR:
lve04147
]
Exosomal proteins
Exosomal proteins of breast cancer cells
103075672 (ERBB2)
CD molecules [BR:
lve04090
]
Proteins
103075672 (ERBB2)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
PK_Tyr_Ser-Thr
Recep_L_domain
GF_recep_IV
Pkinase
Furin-like
TM_ErbB1
ABC1
Haspin_kinase
Kinase-like
CcmD
Tcell_CD4_C
CD34_antigen
APH
Motif
Other DBs
NCBI-GeneID:
103075672
NCBI-ProteinID:
XP_007465231
UniProt:
A0A340XV51
LinkDB
All DBs
Position
Unknown
AA seq
1255 aa
AA seq
DB search
MELAAWCRWGLLLALLPPGAAGTQVCTGTDMKLRLPASPETHLDMLRHLYQGCQVVQGNL
ELTYLPANASLSFLQEIQEVQGYVLIAHNRVSQVPLQRLRIVRGTQLFEDNYALAVLDNG
DLLESATSAARAALGGLQELQLRSLTEMLKGGVLIQRNPQLCHQDTILWKDIFHKNNQLA
LMLIDTNRSRACPPCSPACKAPRCWGESSKDCQSLTRTVCASGCARCKGPQPTDCCHEQC
AAGCTGPKHSDCLACLHFNHSGICELHCPALVTYNTDTFESMPNPEGRYTFGASCVTACP
YNYLSTDVGSCTLVCPLNNQEVTAEDGTQRCEKCSKPCARVCYGLGMEHLREVRAVTSAN
IQEFAGCKKIFGSLAFLPESFEGDRASNTAPLQPEQLRVFESLEEITGYLYISAWPDSLP
DLRVFQNLRVIRGRILHDGAYSLTLQGLGIRWLGLRSLRELGSGLALIHRNARLCFVHTV
PWDQLFRNPHQALLHSANRPEVECVGEGLACYPLCAHGHCWGPGPTQCVNCSQFLRGQQC
VEECRXLLRLPREYVKDRYCLPCHPECQPQNGSVTCFGSEADQCVACTHYKDPPFCVARC
PSGVKPDLSFMPIWKFADEEGMCQPCPINCTHSCVDLDDKGCPAEQRASPVTSIIAAVVG
ILLLVVVGLVFGILIKRRRQKIRKYTMRRLLQETELVEPLTPSGAMPNQAQMRILKETEL
RKVKVLGSGAFGTVYKGIWIPDGENVKIPVAIKVLRENTSPKANKEILDEAYVMAGVGSP
YVSRLLGICLTSTVQLVTQLMPYGCLLDHVREHRGRLGSQDLLNWCVQIAKGMSYLEDVR
LVHRDLAARNVLVKSPNHVKITDFGLARLLDIDETEYHADGGKVPIKWMALESILRRRFT
HQSDVWSYGVTVWELMTFGAKPYDGIPAREIPDLLEKGERLPQPPICTIDVYMIMVKCWM
IDSECRPRFRELVAEFSRMARDPQRFVVIQNEDLGPTSPLDSTFYRSLLEDDDMGDLVDA
EEYLVPQQGFFCPDPAPGSGGTAHRRHRSTSTRSGGGELTLGLEPSEEEPPRSPLAPSEG
AGSDVFDGDLGMGAAKGLQNLPQHDSSPLQRYSEDPTVPLPPETDGYVAPLTCSPQPEYV
NQPEVRPQPPSPLEGPRPPPRPAGSTLERPKTLSPGKNGVVKDIVAFGAAVENPEYLAPR
GRAAPQSHSSPAFSPAFDNLYYWDQDPSERGSPPSTFEGTPTAENPEYLGLDMPV
NT seq
3768 nt
NT seq
+upstream
nt +downstream
nt
atggagctggcggcctggtgccgctgggggctcctcctcgccctcctgccccccggagcc
gcgggcacccaagtgtgcaccggcacagacatgaagctgcggctgccggccagtcccgag
acccacctggacatgctccgccacctctaccagggctgtcaggtggtgcagggtaacctg
gagctcacctacctgcccgctaatgccagcctctccttcctgcaggagatccaggaggtg
cagggctacgtgctcatcgctcacaaccgagtgagtcaggtccccctgcagaggctgcgg
attgtgcgaggcacccagctgttcgaggacaactatgccctggccgtgctggacaatgga
gaccttctcgaaagtgccacgtctgctgcacgcgctgctctgggagggctgcaggagctg
cagctgcgaagcctcacagagatgctgaagggaggggtcttgatccagcggaacccccag
ctctgccaccaggacacgattttgtggaaggacatcttccacaagaacaaccagctggcc
ctcatgctgatagacaccaaccgctcacgggcctgcccaccctgttctccagcttgtaaa
gctccccgctgctggggagaaagttccaaggactgtcagagcttgacgcgaaccgtctgt
gccagcggctgtgcccgctgtaagggcccgcagcccactgactgctgccacgagcagtgt
gctgccggctgcacgggccccaagcactctgactgtctggcctgcctccacttcaaccac
agtggcatctgtgagctgcactgcccagctctggtcacctacaacacggacaccttcgag
tccatgcccaaccccgagggccgttataccttcggcgccagctgcgtgaccgcctgtcct
tacaactacctgtccacggacgtgggatcctgcaccctggtttgtcccctgaacaaccaa
gaggtgacagctgaggatggaacccagcggtgtgagaaatgcagcaagccctgtgcccga
gtgtgctatggtctgggcatggaacacctgcgggaggtgagggcggtcaccagtgccaac
atccaggagtttgctggctgcaagaagatctttgggagcctggcgtttctgccggagagc
tttgagggggaccgagcctccaacactgcccccctacagcctgagcagctcagagtattt
gagtctctggaggagatcacaggttacctgtacatctcagcgtggccagacagcctgccg
gacctccgcgtcttccagaatctgcgagtaatccggggacgaattctgcatgatggtgcc
tactcgctgaccctgcaagggctgggcatccgctggctggggctgcgctcgctgcgggaa
ctgggcagtgggctggccctcatccaccgcaacgcccgcctctgctttgtacacacggtg
ccctgggaccagctcttccggaacccccaccaggccctgctccacagtgccaaccggcca
gaggtcgagtgcgtgggcgagggcctggcctgctacccgctgtgtgcccacgggcactgc
tggggtccagggcccacccagtgcgtcaactgcagccagttccttcggggccagcagtgc
gtggaagaatgccgnnctctcctcaggctcccccgggagtacgtgaaggacaggtactgt
ctgccgtgccaccctgagtgtcagccccagaatggctcagtgacctgctttggctcggag
gctgaccagtgtgtggcttgcacccactacaaggatcctcccttctgcgtggctcgctgc
cccagtggtgtgaagcctgacctctccttcatgcccatctggaagtttgcagatgaggag
ggcatgtgccagccgtgccccatcaactgcacccactcctgtgtggacctggatgacaag
ggctgccccgccgagcagagagccagccctgtgacgtccatcattgccgctgtggtgggc
attctgctgctcgttgtcgtggggctggtcttcggcatcctcatcaagcgacggcggcag
aagatccggaagtatacgatgcggaggctgctgcaggagacagagctggtggagcccctg
acaccgagcggagcgatgccaaatcaggctcagatgcggatcctgaaagagacagagctg
aggaaggtgaaggtgcttggatccggagcttttggcaccgtctacaagggcatctggatc
cccgatggggaaaatgtgaaaatcccagtggccatcaaagtgttgagggaaaacacatcc
cccaaagccaacaaagaaatcttggacgaagcatatgtgatggctggtgtagggtcccca
tacgtgtcccgccttctgggcatctgcctgacatccacggtgcagctggtgacacagctt
atgccctatggctgcctcctagaccacgtccgggagcaccgcgggcgcctgggctcccag
gacctnctgaactggtgtgtgcagattgccaaggggatgagctacttggaggatgtgcgg
ctcgtgcacagggacctggctgcccggaatgtgctggtcaagagtcccaaccatgtcaag
attacagacttcgggctggctcggctgctggacattgatgagacagagtaccatgcggat
gggggcaaggtgcccatcaagtggatggcgttggagtccattctccgccggcggttcacc
caccagagtgatgtgtggagctatggtgtgactgtgtgggagctgatgacttttggcgcc
aaaccttacgatgggatcccagcccgggagatccctgacctcctggagaagggggaacgg
ctgccccagccccccatctgcaccattgatgtctacatgatcatggtcaaatgttggatg
attgactctgaatgtcggccgaggttccgggagttggtggccgaattctcccgcatggcc
agggacccccagcgctttgtggtcatccagaatgaagacttgggccctaccagccccttg
gacagcaccttctaccgctcactgctggaggatgatgacatgggggacctggtggatgct
gaggagtacctggtaccccagcaaggcttcttctgcccagaccctgccccgggctctggg
ggcacagcccaccgcaggcaccgcagcacatccaccaggagtggcggtggtgagctgacg
ctgggtctggagccctcggaggaggagccccccaggtctccgctggcaccttccgaaggg
gccggctctgatgtgtttgacggtgacttgggaatgggggcagccaaggggctgcagaac
ctcccccaacatgactccagccctctacagcggtacagcgaggaccccacagtaccgctt
cctcccgagaccgatggctacgttgcccccctgacctgcagcccccagcccgaatatgtg
aaccagccagaggttcggccacagcccccctcacccctagagggccctcggcctcctcct
cgacctgccggttccactctggaaaggcccaagactctctcccctgggaagaatggggtt
gtcaaagacattgttgcctttggggctgccgtggagaaccccgagtacttggcgccccgg
ggcagggctgcccctcagtcccactcttctccggccttcagcccagcctttgacaacctc
tattactgggaccaggacccatcagagcggggctctccacccagcacctttgaagggacc
cctacagcagagaaccctgagtacctgggtctggacatgccagtatga
DBGET
integrated database retrieval system
