Lipotes vexillifer (Yangtze River dolphin): 103080650
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Entry
103080650 CDS
T03090
Symbol
GART
Name
(RefSeq) trifunctional purine biosynthetic protein adenosine-3
KO
K11787
phosphoribosylamine--glycine ligase / phosphoribosylglycinamide formyltransferase / phosphoribosylformylglycinamidine cyclo-ligase [EC:
6.3.4.13
2.1.2.2
6.3.3.1
]
Organism
lve
Lipotes vexillifer (Yangtze River dolphin)
Pathway
lve00230
Purine metabolism
lve00670
One carbon pool by folate
lve01100
Metabolic pathways
lve01523
Antifolate resistance
Module
lve_M00048
De novo purine biosynthesis, PRPP + glutamine => IMP
Brite
KEGG Orthology (KO) [BR:
lve00001
]
09100 Metabolism
09104 Nucleotide metabolism
00230 Purine metabolism
103080650 (GART)
09108 Metabolism of cofactors and vitamins
00670 One carbon pool by folate
103080650 (GART)
09160 Human Diseases
09176 Drug resistance: antineoplastic
01523 Antifolate resistance
103080650 (GART)
Enzymes [BR:
lve01000
]
2. Transferases
2.1 Transferring one-carbon groups
2.1.2 Hydroxymethyl-, formyl- and related transferases
2.1.2.2 phosphoribosylglycinamide formyltransferase 1
103080650 (GART)
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.3 Cyclo-ligases
6.3.3.1 phosphoribosylformylglycinamidine cyclo-ligase
103080650 (GART)
6.3.4 Other carbon-nitrogen ligases
6.3.4.13 phosphoribosylamine---glycine ligase
103080650 (GART)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
GARS_A
Formyl_trans_N
AIRS_C
GARS_N
GARS_C
AIRS
ATP-grasp
CPSase_L_D2
ATP-grasp_3
ATP-grasp_2
ATP-grasp_4
Dala_Dala_lig_C
LUD_dom
DUF3104
Motif
Other DBs
NCBI-GeneID:
103080650
NCBI-ProteinID:
XP_007469207
UniProt:
A0A340Y9U7
LinkDB
All DBs
Position
Unknown
AA seq
1010 aa
AA seq
DB search
MAAQVLVIGNGGREHTLAWKLAQSNHVKQVLVTPGNAGTACSEKISNTDISISDHTALAQ
FCKDEKIEFVVVGPEAPLAAGIVGSLTSAGVRCFGPTAEAAQLESSKRFAKEFMDRHGIP
TAQWRAFTKAEEACCFIMSADFPALVVKASGLAAGKGVVVAKSKEEACKAVQEIMQDKAF
GEAGETTVIEELLEGEEVSCLCFTDGKTVAPMPPAQDHKRLLEGDQGPNTGGMGAYCPAP
QVSKDLLLKIKNTILQRTVDGMQQEGVPYTGILYAGIMLTKNGPKVLEFNCRFGDPECQV
ILPLLKSDLYEVIQSTLDGLLCTSLPVWLDNRTAVTVVMASKGYPGDYTKGVEITGFPEA
QALGLEVFQAGTALKDGKVVTNGGRVLTVTAIRENLISALEGAKKGLAAIKFEGAIYRKD
IGYRAIAFLQQPRGLTYKDSGVDIAAGNMLVKKIKPLAKATSRPGCDVDLGGFAGLFDLK
AAGFNDPLLACGTDGVGTKLKIAQQCHKHETIGQDLVAMCVNDILAQGAEPLFFLDYFSC
GKLDPSTTEAVVAGIAKACKKAGCALLGGETAEMPDMYPPGEYDLAGFAVGAMERDQKLP
HLERITEGDAVIGIASSGLHSNGFSLVRKIVAKSSLQYSSPAPDGCGGQALGDLLLTPTR
IYSHSLLPVLRSGHVKAFAHITGGGLLENIPRVLPQKFGVDLDAQTWRIPRIFSWLQREG
HLSEEEMARTFNCGIGAALVVSKDLTQQILQDIQQHKEEAWVIGRVVACPEGSPRVKVKH
LIETMQINGSVLENGTLKNHFSVQPKKARVAVLISGTGSNLQALIDSTREPSSSAHIVVV
ISNKAAVSGLDKAERAGIPTRVINHKLYKNRIAFDTTVDQVLEEFSTDIVCLAGFMRILS
GPFVRKWNGKMLNIHPSLLPSFKGSNAHEQVLDAGVTVTGCTVHFVAEDVDAGQIILQEA
VPVKRGDTVETLSERVKLAEHKIFPSALQLVARGTVRLGENGKICWVKEE
NT seq
3033 nt
NT seq
+upstream
nt +downstream
nt
atggcagcccaagtacttgtaattggcaatggaggaagggaacatactctggcctggaaa
cttgcacagtctaatcatgtcaaacaagtgttagttaccccaggaaatgcaggcactgcc
tgctctgaaaagatttcgaacactgacatctcaatcagtgatcacactgcccttgcacag
ttctgcaaagatgagaaaattgaatttgtagttgttggaccagaggcacctctggctgct
ggaattgttgggagcctgacatctgcaggagtgcggtgctttggccctacagcagaagca
gctcagttagagtccagcaagagatttgccaaagagtttatggaccgacatggaatccca
actgcacagtggagagctttcaccaaagctgaagaagcctgctgcttcattatgagtgca
gacttccccgctttggttgtgaaggccagtggtcttgcagctgggaaaggggtagttgtc
gcaaagagcaaagaagaggcctgcaaagctgttcaggagattatgcaggataaagctttt
ggagaagctggagaaacaactgtcattgaagaacttcttgaaggtgaagaggtgtcttgt
ctgtgcttcactgatggaaagactgtggcccccatgcccccagcacaggaccataagcga
ttgctggagggagatcagggccccaacacagggggaatgggagcctattgtccagcacct
caggtttctaaggatttgttgctaaaaattaaaaatactattcttcagaggacagtggat
ggcatgcagcaggagggtgtgccatacacaggtatcctctatgctggtataatgctgacc
aagaatggcccaaaagttctggagtttaattgccgttttggtgatccagagtgccaagtg
atcctcccacttcttaaaagtgacctttatgaagtgattcagtctaccttagatggcctg
ctctgcacatctctgcctgtttggcttgacaaccgcactgccgtaactgtggtcatggca
agtaaaggttatccaggagactacaccaagggtgtagagataacagggtttcctgaggct
caagctttaggactagaggtgttccaagcaggcactgccctaaaagatggcaaagtggtg
actaacgggggtagggtccttacagtaacagccatccgggaaaatctcatctcagccctt
gaaggagccaagaaaggactagctgctataaagtttgagggagccatttataggaaggac
attggctatcgtgccatagctttcctccagcagcccaggggcctgacttacaaggactct
ggggtagacattgcagctggaaatatgctggtcaagaaaattaagcctttagcaaaagcc
acctccagaccaggctgtgatgttgatctcggaggttttgctggtctttttgatttgaaa
gcagccggtttcaacgatcctcttctggcctgtggaacagacggcgttggaactaaactg
aagattgcccagcagtgccataaacatgaaaccattggtcaagatttggttgcaatgtgt
gtaaatgatattctggcacaaggagcggagcccctctttttcctcgattacttttcctgt
ggaaaacttgaccccagtacaactgaagctgttgttgctggaatcgctaaagcttgtaaa
aaagccggatgtgctctcctcggaggtgaaacggcagaaatgcctgacatgtaccctcct
ggagaatatgatctagccggttttgccgttggtgcaatggaacgggatcagaaactccct
cacctggaaagaatcactgaaggggacgctgttattggaatagcttcatctggtcttcac
agcaatggatttagccttgtgaggaaaattgtagcaaaatcttcccttcagtactcctct
ccagcacctgatggctgtggtggccaggccttaggtgatttacttctaactccgaccaga
atctacagccattcactgttacctgtcctgcgttcaggacatgttaaggcctttgcacat
attaccggtgggggattgctagaaaacatccccagagtcctacctcagaaatttggggta
gatttagatgcccagacctggaggatccccaggatcttctcgtggttacagcgggaagga
cacctctctgaagaagagatggccagaacatttaactgtgggattggggctgcccttgtg
gtatcaaaggatctgacacagcagattctgcaggatattcagcagcacaaggaagaagcc
tgggtgatcggcagagtggttgcatgtcctgaaggttctcctcgtgtgaaagtcaagcat
ctgattgaaaccatgcaaataaatggatcagtattggagaatggcaccctgaaaaatcat
ttctctgttcaaccaaaaaaggcaagagtagctgtcttaatatctgggacaggatcaaac
ctccaagctctcatagacagtactagggagccaagtagctctgcacacattgttgttgtg
atctccaacaaagctgcagtgtctggcttagataaagcagaaagagccggaattcccacc
agagtaattaatcataaattatataaaaatcgtatagcatttgacactacagtagaccaa
gtccttgaagagttctccacagacatagtctgtcttgcaggattcatgagaattttatct
ggcccctttgtcagaaaatggaatgggaaaatgctcaacatccacccatccttgctccct
tcgtttaagggttcaaatgcccatgaacaagtcctggatgccggggtcaccgtcactggg
tgcaccgtgcactttgtagctgaagatgtagatgctggacaaattattttacaagaagct
gttccggtgaagaggggtgacactgttgaaactctatctgaaagagtaaaattagcagaa
cacaaaatatttccctcagccctccagctggtggcccgtggaactgtacggcttggagaa
aatggcaaaatctgttgggtcaaagaggaatga
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