Lipotes vexillifer (Yangtze River dolphin): 103081291
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Entry
103081291 CDS
T03090
Symbol
IGF1R
Name
(RefSeq) insulin-like growth factor 1 receptor
KO
K05087
insulin-like growth factor 1 receptor [EC:
2.7.10.1
]
Organism
lve
Lipotes vexillifer (Yangtze River dolphin)
Pathway
lve01521
EGFR tyrosine kinase inhibitor resistance
lve01522
Endocrine resistance
lve04010
MAPK signaling pathway
lve04014
Ras signaling pathway
lve04015
Rap1 signaling pathway
lve04066
HIF-1 signaling pathway
lve04068
FoxO signaling pathway
lve04081
Hormone signaling
lve04114
Oocyte meiosis
lve04140
Autophagy - animal
lve04144
Endocytosis
lve04150
mTOR signaling pathway
lve04151
PI3K-Akt signaling pathway
lve04152
AMPK signaling pathway
lve04211
Longevity regulating pathway
lve04213
Longevity regulating pathway - multiple species
lve04510
Focal adhesion
lve04520
Adherens junction
lve04550
Signaling pathways regulating pluripotency of stem cells
lve04730
Long-term depression
lve04913
Ovarian steroidogenesis
lve04914
Progesterone-mediated oocyte maturation
lve05200
Pathways in cancer
lve05202
Transcriptional misregulation in cancer
lve05205
Proteoglycans in cancer
lve05214
Glioma
lve05215
Prostate cancer
lve05218
Melanoma
lve05224
Breast cancer
lve05225
Hepatocellular carcinoma
Brite
KEGG Orthology (KO) [BR:
lve00001
]
09130 Environmental Information Processing
09132 Signal transduction
04010 MAPK signaling pathway
103081291 (IGF1R)
04014 Ras signaling pathway
103081291 (IGF1R)
04015 Rap1 signaling pathway
103081291 (IGF1R)
04066 HIF-1 signaling pathway
103081291 (IGF1R)
04068 FoxO signaling pathway
103081291 (IGF1R)
04151 PI3K-Akt signaling pathway
103081291 (IGF1R)
04152 AMPK signaling pathway
103081291 (IGF1R)
04150 mTOR signaling pathway
103081291 (IGF1R)
09133 Signaling molecules and interaction
04081 Hormone signaling
103081291 (IGF1R)
09140 Cellular Processes
09141 Transport and catabolism
04144 Endocytosis
103081291 (IGF1R)
04140 Autophagy - animal
103081291 (IGF1R)
09143 Cell growth and death
04114 Oocyte meiosis
103081291 (IGF1R)
09144 Cellular community - eukaryotes
04510 Focal adhesion
103081291 (IGF1R)
04520 Adherens junction
103081291 (IGF1R)
04550 Signaling pathways regulating pluripotency of stem cells
103081291 (IGF1R)
09150 Organismal Systems
09152 Endocrine system
04913 Ovarian steroidogenesis
103081291 (IGF1R)
04914 Progesterone-mediated oocyte maturation
103081291 (IGF1R)
09156 Nervous system
04730 Long-term depression
103081291 (IGF1R)
09149 Aging
04211 Longevity regulating pathway
103081291 (IGF1R)
04213 Longevity regulating pathway - multiple species
103081291 (IGF1R)
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
103081291 (IGF1R)
05202 Transcriptional misregulation in cancer
103081291 (IGF1R)
05205 Proteoglycans in cancer
103081291 (IGF1R)
09162 Cancer: specific types
05225 Hepatocellular carcinoma
103081291 (IGF1R)
05214 Glioma
103081291 (IGF1R)
05218 Melanoma
103081291 (IGF1R)
05215 Prostate cancer
103081291 (IGF1R)
05224 Breast cancer
103081291 (IGF1R)
09176 Drug resistance: antineoplastic
01521 EGFR tyrosine kinase inhibitor resistance
103081291 (IGF1R)
01522 Endocrine resistance
103081291 (IGF1R)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
lve01001
]
103081291 (IGF1R)
09183 Protein families: signaling and cellular processes
04090 CD molecules [BR:
lve04090
]
103081291 (IGF1R)
Enzymes [BR:
lve01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.10 Protein-tyrosine kinases
2.7.10.1 receptor protein-tyrosine kinase
103081291 (IGF1R)
Protein kinases [BR:
lve01001
]
Receptor tyrosine kinases (RTK)
INSR family [OT]
103081291 (IGF1R)
CD molecules [BR:
lve04090
]
Proteins
103081291 (IGF1R)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
PK_Tyr_Ser-Thr
Recep_L_domain
Furin-like
Pkinase
fn3
Ig_DSCAM-DSCAML_C
Kinase-like
Insulin_TMD
Motif
Other DBs
NCBI-GeneID:
103081291
NCBI-ProteinID:
XP_007470151
UniProt:
A0A340Y906
LinkDB
All DBs
Position
Unknown
AA seq
1367 aa
AA seq
DB search
MKSGSGGGSPTSLWGLLFFSAALSLWPTSGEICGPGIDIRNDYQQLKRLENCTVIEGYLH
ILLISKAEDYRSYRFPKLTVITEYLLLFRVAGLESLGDLFPNLTVIRGWKLFYNYALVIF
EMTNLKDIGLYNLRNITRGAIRIEKNADLCYLSTVDWSLILDAVSNNYIVGNKPPKECGD
LCPGTMEEKPLCEKTTINNEYNYRCWTTNRCQKMCPSTCGKRACTENHECCHPECLGSCS
APDNDTACVACRHYYYAGVCVPSCPPNTYRFEGWRCVDRDFCANIPNAESSDSEGFVIHD
GECMQECPSGFIRNGSQSMYCIPCEGPCPKVCEEEKKTKTIDSVTSAQMLQGCTIFKGNL
LINIRRGNNIASELENFMGLIEVVTGYVKIRHSHALVSLSFLKNLRQILGEEQLEGNYSF
YVLDNQNLQQLWDWDHRNLTIKAGKMYFAFNPKLCVSEIYRMEEVTGTKGRQSKGDINTR
NNGERASCESDVLHFTSTTTWKNRIIITWHRYRPPDYRDLISFTVYYKEAPFKNVTEYDG
QDACGSNSWNMVDVDLPPNKDVEPGILLHGLKPWTQYAVYVKAVTLTMVENDHIRGAKSE
ILYIRTNASVPSIPLDVLSASNSSSQLIVKWNPPSLPNGNLSYYIVRWQRQPQDSYLYRH
NYCSKDKIPIRKYADGTIDIEEVTENPKTEVCGGEKGPCCACPKTEAEKQAEKEEAEYRK
VFENFLHNAIFVPRPERKRREVMQVTNTTMSSRNRNTTVVDTYNITDPEELETEYPFFES
RVDNKERTVISNLRPFTLYRIDIHSCNHEAEKLGCSASNFVFARTMPAEGADDIPGPVTW
EPRPENSIFLKWPEPENPNGLILMYEIKYGSQVEDQRECVSRQEYRKYGGAKLNRLNPGN
YTARIQATSLSGNGSWTDPVFFYVQAKTTYENFIHLIIALPIAVLLIVGGLVIMLYVFHR
KRNNSRLGNGVLYASVNPEYFSAADVYVPDEWEVAREKITMSRELGQGSFGMVYEGVAKG
VVKDEPETRVAIKTVNEAASMRERIEFLNEASVMKEFNCHHVVRLLGVVSQGQPTLVIME
LMTRGDLKSYLRSLRPEMENNPVLAPPSLSKMIQMAGEIADGMAYLNANKFVHRDLAARN
CMVAEDFTVKIGDFGMTRDIYETDYYRKGGKGLLPVRWMSPESLKDGVFTTHSDVWSFGV
VLWEIATLAEQPYQGLSNEQVLRFVMEGGLLDKPDNCPDMLFELMRMCWQYNPKMRPSFL
EIISSIKDEMEPGFREVSFYYSEENKPPEPEELDLEPENMESVPLDPSASSSSLPLPDRH
SGHKAENGPGPGVLVLRASFDERQPYAHMNGGRKKERALPLPQSSTC
NT seq
4104 nt
NT seq
+upstream
nt +downstream
nt
atgaagtctggctccggaggagggtccccgacctcgctgtgggggctcctatttttctcc
gccgcgctctcgctctggccgacgagtggagaaatctgtgggccaggcatcgacatccgc
aacgactaccagcagctgaagcggctggagaactgcacggtgatcgagggctacctccac
atcctgctcatttccaaggctgaggactaccgcagctaccgcttccccaagctcacggtc
atcactgagtacctgctgctgttccgtgtggccggcctcgagagccttggcgacctcttc
cccaacctcacagtcatccgtggctggaagctcttttacaactacgccctggtcatcttc
gagatgaccaacctcaaggatattgggctctacaacctgcgaaacattacccgtggggcc
atccggatcgagaagaatgctgacctctgctacctctccacggtggactggtccctaatc
ctggatgccgtgtccaataactacatcgtggggaataagcccccaaaggagtgtggggac
ctgtgcccggggacgatggaggagaagccgctgtgcgagaagacgaccatcaacaacgag
tacaactaccgctgctggaccacaaaccgctgtcagaaaatgtgcccgagcacgtgcggg
aagcgggcgtgcacggagaaccacgagtgctgccaccccgagtgcctgggcagctgcagc
gcgcccgacaacgacacggcctgcgtggcctgccgccactactactatgccggtgtctgt
gtgcccagctgcccgcccaacacctaccgcttcgagggctggcgttgtgtggaccgtgac
ttctgcgccaacatccccaatgctgagagcagcgattccgagggcttcgtgatccacgac
ggcgagtgcatgcaggagtgcccatcgggcttcatccgcaacggcagccagagcatgtac
tgcatcccttgcgaaggcccttgtcccaaagtgtgtgaggaagagaaaaagacaaagacc
attgattctgtgacttctgctcagatgctccaaggatgcaccatcttcaagggcaatcta
ctcattaatatccgacgcggcaacaacatcgcttcggaactggagaacttcatgggactc
atcgaggtcgtgacgggctacgtgaagatccgccactctcatgccttggtctccttgtcc
ttcctgaagaaccttcgccagatcctaggagaggagcagctagaggggaattactccttc
tacgtcctcgacaaccagaacttgcagcagctgtgggactgggaccaccgcaacctgacc
atcaaagccgggaaaatgtactttgctttcaatcccaaactgtgtgtttccgagatttac
cgcatggaggaagtgacggggactaaagggcgccagagcaaaggggacataaacaccagg
aacaatggagagagagcctcctgtgaaagtgacgtcctgcacttcacctccaccaccacg
tggaagaaccgcatcatcatcacctggcaccggtaccggccccctgactacagggacctc
atcagcttcaccgtctactacaaggaagcaccctttaaaaacgtcacagagtatgacggg
caggatgcctgcggctccaacagctggaacatggtagatgtggacctcccacccaacaag
gacgtggagcccggcattttactgcacggactgaagccctggacacagtatgccgtttac
gtcaaggctgtgaccctcaccatggtggagaatgaccacatccgtggagccaagagcgag
atcttgtacattcgcaccaatgcttcagttccttccatccccctggatgtactctcagca
tcaaactcctcttctcagctgatcgtgaagtggaaccctccttccctgcccaacggcaac
ctgagctactacatcgtaaggtggcagcgccagccccaggacagctacctttaccggcac
aattactgctccaaagacaaaatccccatcaggaagtacgccgatggcaccatcgacatt
gaggaggtgacggagaatcccaagaccgaagtctgtggtggggagaaagggccgtgctgc
gcttgccccaaaaccgaagccgagaagcaggccgagaaggaggaggctgagtaccgcaag
gtcttcgagaatttcctgcacaacgccatcttcgtgcccagacctgaacggaagcggagg
gaggtcatgcaggtcaccaacaccaccatgtccagccggaacaggaacaccacggtggtg
gacacctacaacatcacagacccggaagagctcgagaccgagtaccctttcttcgagagc
agagtggataacaaggagagaactgtcatctccaacctccggccttttactctgtaccga
atcgatatccacagctgtaaccacgaagctgagaagcttggctgcagcgcctccaacttt
gtctttgcaagaaccatgcctgcagaaggagcagatgacattcctgggccagtgacctgg
gagccaaggcctgagaactccatctttttaaaatggccagaacctgagaatcccaatgga
ttgattttaatgtatgaaataaaatatggatcacaagtcgaggatcagcgggaatgtgtg
tccagacaggagtacaggaagtacggaggggccaagctaaaccggctcaacccggggaac
tacacggcccggatccaggccacctctctctctgggaacgggtcgtggactgatcctgtg
ttcttctatgtccaggccaaaacaacgtatgaaaacttcatccatctgatcattgctctg
cccattgccgttctgctgatagtaggagggttggttataatgctgtacgtcttccataga
aaaagaaataacagcaggctggggaacggagtgctgtatgcctctgtgaacccggagtac
ttcagtgcagccgatgtgtacgtgcctgacgagtgggaggtcgcccgggagaagatcacc
atgagccgggagttggggcagggctcgttcgggatggtttacgaaggtgtcgccaagggc
gtggtcaaggatgagcctgagaccagggtggccattaagacggtgaacgaggccgccagc
atgcgtgagaggattgagtttctcaacgaggcctcggtgatgaaggagttcaactgtcac
catgtggtgcgcttgctgggcgtggtatcccagggtcagccgacgctggtcatcatggaa
ctgatgacccggggggacctcaaaagttatctccggtctctgaggccagaaatggagaat
aatccagtcctagcacctcccagcctaagcaaaatgatccagatggctggagagattgca
gatggcatggcatacctcaacgccaataagtttgtccacagagacctcgctgcccggaac
tgcatggtggccgaagatttcacagtcaaaatcggagattttgggatgacgagagacatc
tatgagaccgactattaccggaagggagggaaggggctgctgcccgtgcgctggatgtcc
cctgagtccctcaaggatggagtcttcaccacgcactctgacgtctggtccttcggggtc
gtcctctgggaaatcgccacgctggccgagcagccataccagggcctgtccaatgagcaa
gtccttcgcttcgtcatggagggtggccttctggacaagccggacaactgtcctgacatg
ctgtttgaactgatgcgcatgtgctggcagtacaaccccaagatgaggccttccttcctg
gaaatcatcagcagcatcaaggacgagatggagcccggcttccgggaggtctccttctac
tacagcgaggagaacaagccacctgagccagaggagctggacctagagccggagaacatg
gagagtgtccccttggacccctcggcatcctcgtcctccctgccactgcccgacagacac
tcaggacacaaggccgagaacggtccgggccctggcgtgctggtccttcgagccagcttc
gacgagagacagccttatgcgcacatgaacgggggccgcaagaaggagcgggccttgcct
ctgccccagtcctcgacctgctga
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integrated database retrieval system
