Lipotes vexillifer (Yangtze River dolphin): 103081332
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Entry
103081332 CDS
T03090
Symbol
TYK2
Name
(RefSeq) non-receptor tyrosine-protein kinase TYK2
KO
K11219
non-receptor tyrosine-protein kinase TYK2 [EC:
2.7.10.2
]
Organism
lve
Lipotes vexillifer (Yangtze River dolphin)
Pathway
lve04217
Necroptosis
lve04380
Osteoclast differentiation
lve04620
Toll-like receptor signaling pathway
lve04621
NOD-like receptor signaling pathway
lve04630
JAK-STAT signaling pathway
lve04658
Th1 and Th2 cell differentiation
lve04659
Th17 cell differentiation
lve05145
Toxoplasmosis
lve05160
Hepatitis C
lve05161
Hepatitis B
lve05162
Measles
lve05164
Influenza A
lve05165
Human papillomavirus infection
lve05167
Kaposi sarcoma-associated herpesvirus infection
lve05168
Herpes simplex virus 1 infection
lve05169
Epstein-Barr virus infection
lve05171
Coronavirus disease - COVID-19
Brite
KEGG Orthology (KO) [BR:
lve00001
]
09130 Environmental Information Processing
09132 Signal transduction
04630 JAK-STAT signaling pathway
103081332 (TYK2)
09140 Cellular Processes
09143 Cell growth and death
04217 Necroptosis
103081332 (TYK2)
09150 Organismal Systems
09151 Immune system
04620 Toll-like receptor signaling pathway
103081332 (TYK2)
04621 NOD-like receptor signaling pathway
103081332 (TYK2)
04658 Th1 and Th2 cell differentiation
103081332 (TYK2)
04659 Th17 cell differentiation
103081332 (TYK2)
09158 Development and regeneration
04380 Osteoclast differentiation
103081332 (TYK2)
09160 Human Diseases
09172 Infectious disease: viral
05161 Hepatitis B
103081332 (TYK2)
05160 Hepatitis C
103081332 (TYK2)
05171 Coronavirus disease - COVID-19
103081332 (TYK2)
05164 Influenza A
103081332 (TYK2)
05162 Measles
103081332 (TYK2)
05168 Herpes simplex virus 1 infection
103081332 (TYK2)
05167 Kaposi sarcoma-associated herpesvirus infection
103081332 (TYK2)
05169 Epstein-Barr virus infection
103081332 (TYK2)
05165 Human papillomavirus infection
103081332 (TYK2)
09174 Infectious disease: parasitic
05145 Toxoplasmosis
103081332 (TYK2)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
lve01001
]
103081332 (TYK2)
Enzymes [BR:
lve01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.10 Protein-tyrosine kinases
2.7.10.2 non-specific protein-tyrosine kinase
103081332 (TYK2)
Protein kinases [BR:
lve01001
]
Non-receptor tyrosine kinases
JAK family [OT]
103081332 (TYK2)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
PK_Tyr_Ser-Thr
Pkinase
Jak1_Phl
FERM_F2
FERM_F1
SH2_1
Kinase-like
Kdo
FERM_C_FAK1
ABC1
Haspin_kinase
RIO1
Motif
Other DBs
NCBI-GeneID:
103081332
NCBI-ProteinID:
XP_007460724
UniProt:
A0A340XN66
LinkDB
All DBs
Position
Unknown
AA seq
1186 aa
AA seq
DB search
MPLCQWGATTRGRKPDGNGAQPMATRGGLKVLLHWAGPGGGEPWVTFSEATLTAEEVCLH
IAHKVGITPPCFNLFALFDVQAQVWLPPNHILDMSRDSSLMLYFRMRFYFRNWHGMHPQE
PAVYRCGPPGSEPSSEQAEQGVQLLDPASFEYLFEQGKHEFVNDVAPLWELSSEEEIHHF
QNESLGMAFLHLCHLALCHGVPLEKVAKKISFKDCIPRSFRRQIRQHNALTRLRLRSIFR
KFLRAFQPGCLSQQVVMVKYLATLERLAPRFGTERVPVCHLELLAQAEGEPCYIRDGGQA
PPDPGPESAAGPPTHEVLVSGTDGIQWRLVQAEVSGAPLPSSSPGRVPHAGPSGKKAKAQ
EVGNQPVHRPQEAPWAYFCDFQDITHVVLKERRVSIHCQDNKCLELTLPSRAAALSLVSL
VDGYFRLTADSSHYLCHEVAPPRLVMSIQDGIHGPLLEPFVLARLQPEDGLYLIHWSTSH
LHRLILTVVQRDQAPGVKGLHLRKFPIQLQAGTVALEGWDRSFPSVRELRVALQGCSLRA
GDDCFSLHHCCLPQPGEISNLIVTRGPRASSRPLNLSHLRFHQVRQEDITQLSHLGQGTR
TNVYEGLLRVGGGGPEEDKVDGGDPPMPGAGCEQELRVVLKVLDPSHRDIALAFYETASL
MSQVSHVHLVFVHGIYMQGSDNIMVTEYVEHGPLDVWLRRERGHVPLAWKLAVAQQLASA
LSYLEDKRLVHSNVCGRNILLARLGLAEGTSPFIKLSDPGVGLSALSREERVERIPWTAP
ECLSGGANSLSTAADKWGFGATLLEICFDGEAPLQGRSPSEKECFYQKQHKLPEPSCPEL
AILTSQCLTYEPAQRPSFRTILRDLTQLQPQNLVDVLSVNPDSSVSDPTVFHKRYLKKIR
DLGEGHFGKVSLYCYDPTNDGTGEVVAVKALKAGCGPQLRTGWRREIEILRTLYHEHIVK
YKGCCEDQGEKSVQLVMEYVPLGSLRDYLPRHNVGLAQLLLFSQQICEGMAYLHAQHYVH
RDLAARNVLLDNNRLVKIGDFGLAKAVPEGHEYYCVREDGDSPVFWYAPECLKECKFYYA
SDVWSFGVTMYELLTYCDSTQSPPSKFIELIGLTQGQMTVLRLTELLERGERLPQPEKCP
CEIYGLMKNCWKAEASFRPTFQNLIPILKTVHEKYQGQAASAFSVC
NT seq
3561 nt
NT seq
+upstream
nt +downstream
nt
atgcctctgtgccaatggggggccaccaccaggggcagaaagcccgatgggaatggagct
cagcccatggccaccagaggaggcctgaaggtgcttctgcactgggccggccccggtggc
ggggagccctgggtcaccttcagcgaggccacactaactgcggaggaggtctgcctccac
attgcacacaaagtcggcatcactccaccctgcttcaatctttttgccctcttcgatgtc
caggcccaggtctggctgcctccaaaccacatcctggatatgtccagagactcgagcctg
atgctgtacttccgcatgaggttttatttccggaactggcatggcatgcatccccaggag
ccggctgtgtaccgctgcggtcccccagggtccgagccttcctcagaacaggccgagcag
ggggtgcaactcctggaccccgcctcctttgagtacctctttgagcagggcaagcatgag
tttgtaaatgatgtggcaccgctgtgggagctgtcaagcgaggaggagatccaccacttt
cagaacgagagcctgggcatggcctttttgcacctctgccacctcgctctctgccatggt
gtcccccttgagaaggtggccaagaagatcagcttcaaggactgcatcccacgctccttc
cggcggcagatccggcagcacaatgctctgacgcggctgcgcctgcggagcatcttccgc
aagttcctgcgggccttccagccgggctgcctctcccagcaggttgtcatggtgaagtac
ctggccacactcgagcggctggcgccccgcttcggcacagagcgcgtgcccgtgtgccac
ctggagctactggcccaggccgagggggagccctgctacatccgggatggtggacaggcc
cctcccgaccccgggcccgagtctgccgcaggaccccccacccacgaggtgctggtgtcg
ggcaccgacggcatccagtggcggctggtacaggcagaggtgagtggggcgccccttcca
tctagcagtccaggaagggtgccccatgctggcccatctgggaagaaagccaaggcccag
gaggtgggcaaccagccagtgcacagacctcaggaggccccatgggcctacttctgcgac
ttccaggacatcacccacgtggtgctgaaagaacgccgcgtcagcattcattgtcaggac
aacaagtgcctggagttgaccctgccttcccgggctgcggccctgtccttggtgtcactg
gtggatggctacttccgcctgacggccgactcaagccactacctatgccacgaggtggct
cctccacggctggtgatgagtatccaggatggtatccacggacccctgctggagccattt
gtgctggccaggctgcagcccgaggatggcctctacctcatccactggagcaccagccac
ctccaccgccttatcctcacggtggtccagcgcgaccaggcacccggcgtgaagggcttg
cacctgcggaagttccccatccagctgcaggctgggactgtcgcgctggagggctgggac
cggtccttccccagcgtgcgcgagctgcgggttgccctgcagggctgctccctgcgggcc
ggcgacgactgcttttccctgcaccactgctgcctgccacagccgggagagatctccaac
ctcatcgtcacgcggggacctcgggccagcagcaggccactcaacctcagccatctcaga
ttccaccaggtccgccaggaagacatcacccagctgtcccacttgggccagggcacgagg
accaacgtgtatgagggcctcttgcgagtggggggcggaggccccgaggaggacaaggtg
gatggcggggacccccccatgcccggggcgggctgtgaacaggagctgcgagtggtactc
aaggtgctagatcccagtcaccgtgacatcgccctggccttctacgagacagccagcctc
atgagccaggtctcccacgtgcacctggtcttcgtgcacggcatctacatgcagggctcc
gacaacatcatggtgacggagtacgtggagcacgggcccctggacgtgtggctgcggcgg
gagaggggccacgtgcccctggcctggaagctggcagtggcccagcagctggccagcgcc
ctcagctacctggaagacaagaggctggttcacagcaacgtgtgtggccggaacatcctc
ctggcacggctggggctggcggagggcaccagccccttcatcaagttgagtgaccccggt
gtgggcctgagcgccctctccagggaggaacgggtggagcggatcccctggacagcccct
gagtgcctgtccggtggagccaacagcctaagcactgcagccgacaagtggggctttggt
gccaccctcctggagatctgcttcgatggggaggcccccctgcagggccgcagcccctcc
gagaaagagtgcttctaccagaagcagcacaagctgcctgagccctcgtgcccagagctg
gccatactcaccagccagtgcctgacctatgagccagcccagcggccatccttccgcacc
atcctgcgtgacctcactcagctgcagccccaaaatctcgttgatgtcttgtctgtgaac
ccggactcatcggtgtcagatcctacggttttccacaagcgctatttgaaaaagatccgg
gatctgggtgagggtcacttcggaaaggtcagcttgtactgctacgatccaaccaatgac
ggcactggtgaggtggtggctgtgaaggccctcaaggcaggctgcggtccccagctccgt
acaggctggaggcgagagatcgaaatcttgcgcacactctaccacgagcacattgtcaag
tacaagggctgctgcgaggaccaaggcgagaagtcggtacagctggtcatggagtatgtg
cccctgggcagcctccgagactacttgccccggcacaacgtcgggctggcccagctgctg
ctcttctcccagcagatctgtgagggtatggcctacctgcacgcgcagcactacgtgcac
cgagacctggccgcacgcaatgtgctgctggacaacaacaggctggtcaagattggggac
ttcggcctcgccaaggccgtgcccgaaggccatgagtactactgcgtgcgcgaggatggg
gacagccccgtgttctggtatgccccggagtgcctgaaggagtgtaagttctactatgca
tccgacgtctggtcctttggggtcaccatgtatgagctgctgacctactgtgactccacc
cagagccccccctcgaaattcatcgagctcataggcctcacccaggggcagatgacagtg
ctgaggctcactgagctgctggaacgaggggagaggctgccacagccagagaaatgtccc
tgtgagatctatggcctcatgaagaactgctggaaagcagaggcctctttccgcccgaca
ttccagaacctcatacccatcctcaaaacggtccacgagaaataccaaggccaggcagcc
tcagcgttcagtgtctgctga
DBGET
integrated database retrieval system
