Lipotes vexillifer (Yangtze River dolphin): 103082965
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Entry
103082965 CDS
T03090
Symbol
GCLC
Name
(RefSeq) glutamate--cysteine ligase catalytic subunit isoform X1
KO
K11204
glutamate--cysteine ligase catalytic subunit [EC:
6.3.2.2
]
Organism
lve
Lipotes vexillifer (Yangtze River dolphin)
Pathway
lve00270
Cysteine and methionine metabolism
lve00480
Glutathione metabolism
lve01100
Metabolic pathways
lve01240
Biosynthesis of cofactors
lve04216
Ferroptosis
Module
lve_M00118
Glutathione biosynthesis, glutamate => glutathione
Brite
KEGG Orthology (KO) [BR:
lve00001
]
09100 Metabolism
09105 Amino acid metabolism
00270 Cysteine and methionine metabolism
103082965 (GCLC)
09106 Metabolism of other amino acids
00480 Glutathione metabolism
103082965 (GCLC)
09140 Cellular Processes
09143 Cell growth and death
04216 Ferroptosis
103082965 (GCLC)
Enzymes [BR:
lve01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.2 glutamate---cysteine ligase
103082965 (GCLC)
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Ortholog
Paralog
GFIT
Motif
Pfam:
GCS
GCS2
SANT_DAMP1_like
Motif
Other DBs
NCBI-GeneID:
103082965
NCBI-ProteinID:
XP_007460863
UniProt:
A0A340XHI5
LinkDB
All DBs
Position
Unknown
AA seq
637 aa
AA seq
DB search
MGLLSQGSPLSWEETQRHADHVRLHGILQFLHIYHAVKDRHKDVLKWGDEVEYMLVSFDH
ENKKAQLVLSGEELLETLQEKGERTNPNHPTLWRPEYGSYMIEGTPGQPYGGTMSEFNTV
EDNMRKRRKEATSLLGENQALCTITSFPRLGCPGFTLPEFKPNPVEGGASKSLFFPDEAI
NKHPRFSTLTRNIRHRRGEKVVINVPIFKDKNTPSPFIETFPEDDEAAKASKPDHIYMDA
MGFGMGNCCLQVTFQACSISEARYLYDQLATICPIVMALSAASPFYRGYVSDIDCRWGVI
SASVDDRTREERGLEPLKNNHYRISKSRYDSIDSYLSECGEKYNDIDLTKDKEIYEQLLQ
QGIDHLLAQHVAHLFIRDPLTLFEEKIHLDDANESDHFENIQSTNWQTMRFKPPPPNSDI
GWRVEFRPMEVQLTDFENSAYVVFVVLLTRVILSYKLDFLIPLSKVDENMKVAQKRDAVL
QGLFYFRKDICKGGNAMVDGRGKTTGSTEPAAEEYTLMTIDTIINGKEGVFPGLIPILNS
YLENMEVDVDTRCSILNYLKLIKKRASGELMTVARWMREFIANHPDYKQDSVITDEMNYS
LLLKCNQIANELCECPELLGPAFRKVKYSGSKTDSSN
NT seq
1914 nt
NT seq
+upstream
nt +downstream
nt
atggggctactgtcccagggctcgccactgagctgggaggagacccagcgccacgccgac
cacgtgcggctgcacgggatcctccagttcctgcacatctaccacgccgtcaaggaccgg
cacaaggacgtgctcaagtggggcgacgaggtggaatacatgttggtatcttttgatcat
gaaaataaaaaagcccaactggtactgtctggagaggaacttcttgaaactctgcaagaa
aagggggaaaggacaaacccaaaccaccctaccctttggagaccagagtatgggagctac
atgatcgaggggacacctggccagccgtacggagggaccatgtctgagttcaacacggtc
gaggacaacatgaggaagcgccgcaaggaagcgacatctctgctgggggaaaaccaggcc
ctctgcacaatcacttcgtttcccagattaggctgccctgggttcacgctgcccgagttc
aagcccaacccagtggaaggaggagcttccaagtccctcttctttcctgatgaagcgata
aacaagcacccgcgcttcagtaccctcaccaggaacatccggcacagaagaggagaaaag
gttgtcatcaacgtcccaatatttaaggacaagaatacaccatctccatttatagaaaca
tttcctgaggatgatgaggcagcaaaggcttctaagcccgaccacatttacatggatgct
atgggctttgggatgggcaattgctgtctgcaggtaacgttccaagcctgcagcatatct
gaggccagatacctttatgatcagttggccactatctgcccaattgtcatggctttgagc
gctgcgtctcctttttaccgaggctatgtgtcagacattgattgtcgctggggcgtgatt
tctgcatctgtagatgatagaactcgggaggagagaggactggagccactgaagaacaac
cactataggatcagtaagtcccgatacgattcaatagacagttacttatctgagtgcggt
gagaaatacaatgacatcgacctgacgaaagacaaagaaatctatgaacagcttttgcag
caaggcatcgatcatctcctggcccagcacgtggctcatctcttcattagagacccgctg
actctgtttgaagagaaaatccacctggacgatgccaatgagtccgaccattttgagaat
attcagtccacaaattggcagacaatgcgatttaaacctcctcctccaaactccgacatt
ggatggagagtggaattccggcccatggaggttcagttgacagacttcgagaactccgcg
tacgtggtgttcgtggtgctgctcaccagggtgatcctttcctacaaactggactttctc
atcccgctgtcaaaggttgatgagaacatgaaagtagcacagaagcgagatgccgtcctg
cagggattgttttatttcagaaaagatatttgcaaaggtggcaatgccatggtggacggc
cgcggcaagaccacgggcagcaccgagccagcagccgaggagtacacgctcatgaccatc
gacaccatcatcaacggcaaggaaggcgtgttccccgggctgatccccatcctgaactct
tacctggaaaacatggaggtggacgtggacaccagatgcagtattctgaactacctgaaa
ctgattaagaagagagcatccggagaattaatgacagttgccagatggatgagggagttc
atcgcaaaccatccagactacaagcaagacagtgtaataactgacgagatgaactatagc
cttcttttaaagtgtaaccaaatcgcaaatgaattatgtgaatgcccagagttacttgga
ccagcatttaggaaagtaaagtacagtggaagtaaaactgactcttccaactag
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