Lipotes vexillifer (Yangtze River dolphin): 103084669
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Entry
103084669 CDS
T03090
Symbol
FPGS
Name
(RefSeq) folylpolyglutamate synthase, mitochondrial isoform X1
KO
K01930
folylpolyglutamate synthase [EC:
6.3.2.17
]
Organism
lve
Lipotes vexillifer (Yangtze River dolphin)
Pathway
lve00790
Folate biosynthesis
lve01100
Metabolic pathways
lve01240
Biosynthesis of cofactors
lve01523
Antifolate resistance
lve04981
Folate transport and metabolism
Brite
KEGG Orthology (KO) [BR:
lve00001
]
09100 Metabolism
09108 Metabolism of cofactors and vitamins
00790 Folate biosynthesis
103084669 (FPGS)
09150 Organismal Systems
09154 Digestive system
04981 Folate transport and metabolism
103084669 (FPGS)
09160 Human Diseases
09176 Drug resistance: antineoplastic
01523 Antifolate resistance
103084669 (FPGS)
Enzymes [BR:
lve01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.17 tetrahydrofolate synthase
103084669 (FPGS)
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Paralog
GFIT
Motif
Pfam:
Mur_ligase_M
Mur_ligase_C
Motif
Other DBs
NCBI-GeneID:
103084669
NCBI-ProteinID:
XP_007471802
UniProt:
A0A340YH75
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All DBs
Position
Unknown
AA seq
580 aa
AA seq
DB search
MSRARGHLRAALFLAAVSSRGATTGVAARRVLSAWPAPQEPGMEYQDAVRTLNTLQTNAN
YLEQVKRQRGDPQTQLEAMRLYLARSGLQVEDLDQLNIIHITGTKGKGSTCAFTERILRS
YGLKTGFFSSPHLVQVRERIRINGQPISPELFTKHFWRLYHRLEETKDDSSCVSMPGYFR
FLTLMAFHVFLQEKVDLAVMEVGIGGAYDCTNIVKKPVVCGVSSLGIDHTGLLGDTMEKI
AWQKGGIFKCGVPAFTVLQPDGPLAVLRDRAQQISCPLYLCPPLEALEEGGPLLTLGLEG
EHQQSNAALALQLARCWLQQKGYRDTGELKASRPSLLGQLPLAPVFQPTSHMQHGLRDTE
WPGRTQLLRRGPLTWYLDGAHTTSSMQACVRWFRQALQSRGRPSGGSEVRVLLFNSTGDR
DSAALLKLLQPCQFDYTIFCPNLTEVSSTDNADQQNFTVTLDQVLLRCLAHQQHWSRLHE
DQASPEPGGPAPLLLAPRPAHTHSASSLVFSCISHALQWISQGRDPVFQPPSPPRVLFAH
PVAGSGAIVLQEAAAIHVLVTGSLHLVGGVLKLLEPSLSQ
NT seq
1743 nt
NT seq
+upstream
nt +downstream
nt
atgtcgcgggcacgcggccacctgcgcgcggctctcttcctggcagcggtttcttcgcgt
ggtgcaacaaccggggtcgcagcgaggcgagtattgagcgcgtggcctgcgccgcaggag
cccggcatggagtatcaggatgctgtgcgcacactcaacaccctgcagaccaatgccaac
tacttggagcaggtgaagcgtcagcggggtgacccccagacacaactggaagccatgagg
ctatacttggcacggagtgggctgcaggtcgaggacttggaccaactgaacattatccac
atcactgggaccaaggggaagggctccacctgtgccttcactgaacgtatcctccgaagc
tatggcctgaagacgggattctttagctctccccacctggtgcaggtgcgtgagcggatc
cgaatcaatgggcagcccataagccccgagctcttcaccaagcacttctggcgcctctac
caccggctggaggagaccaaggatgacagcagctgtgtctccatgcctggctacttccgc
ttcctcacactcatggccttccatgtcttcctccaagagaaggtggacctggcagtgatg
gaagtgggcatcggcggggcttacgactgcaccaacatcgtcaagaagcctgtggtgtgt
ggggtctcctctcttggcatcgaccacactggccttctgggggacacgatggagaagatc
gcatggcagaaagggggcatttttaagtgtggcgtccctgccttcaccgtgctccagcct
gacgggcccctggcagtgctgagggaccgcgctcagcagatctcatgtcccctctacctg
tgcccaccactagaagccctggaggaaggggggccactgctgaccctgggcctggagggg
gagcatcagcagtccaatgccgccttggccttgcagctggctcgctgctggctgcagcaa
aagggctaccgggatactggggagctgaaggcgtccaggccaagcctcctggggcagctg
cccctggcacctgtgttccagcccacgtcccacatgcagcatgggcttcgggacacggag
tggccgggccggacgcagttgctgcggcggggccccctcacttggtacctggacggcgcg
cacaccaccagcagcatgcaggcctgcgtgcgctggttccgccaggcgctgcaaagccgc
gggaggccgagcggcgggtctgaggtgcgtgtcttgctcttcaactccactggggaccgg
gattccgcggccctgctgaagctgctgcagccctgccagtttgactataccattttctgc
cctaacctgacagaggtgtcatccacggacaacgcagaccaacagaacttcacagtgacc
ctggaccaggtgctgctccgctgccttgcgcaccagcaacactggagccgcctgcacgag
gaccaggcgagcccggagcctggtgggcctgcacccctgctgctggcaccccgcccagcc
cacacccacagcgccagctccctcgtcttcagctgcatttcccacgccttgcagtggatc
agtcaaggccgggaccctgtctttcagccaccaagtcccccacgggtcctctttgcccac
cctgtggcaggcagtggggccatcgtcctccaggaggctgctgccatccacgtgctggtc
acaggcagcctgcacctggtgggcggtgtgctgaagctgctggagccctccctgtcccag
taa
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